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Increased Oxidant Stress and Inflammation in Patients with Chronic Schizophrenia

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International Journal of Clinical Medicine 2012年第5期3卷 368-376页

作者： aysenur Yegin Nurullah ay Ozgur aydin Nedim Yargici Esin Eren Necat Yilmaz Central Laboratory Ataturk Hospital of Ministry of Health Antalya Turkey Central Laboratory Department of Biochemistry Antalya Educational and Research Hospital Antalya Turkey Department of Psychiatry Antalya Educational and Research Hospital Antalya Turkey

Background: Several lines of evidence, including postmortem studies, suggest increased oxidative stress and inflammation in patients with schizophrenia. Alteration of oxidative stress markers has been reported in schizoprenia studies, but with inconsistent results. Oxidized low-density lipoproteins (oxLDL) have been reported to be capable of eliciting neurocytotoxicity. On the other hand, paraoxonase (PON1), an arylesterase(ARE), plays a role in protection against oxidative modifications of LDL and is considered to be one of the antioxidant enzymes. There are no studies showing the changes in oxidative stress and inflammation together, nor the activities of PON1 and ARE in schizophrenic patients. In this study, we examined PON1, ARE activities and oxidative/anti-oxidative markers in patients with chronic schizophrenia and healthy controls. Methods: We recruited 30 male chronic schizophrenic patients and 30 male healthy control subjects and examined C-reactive protein(CRP), fibrinogen, PON1, ARE and plasma total antioxidant status (TAS) and total oxidant status (TOS), oxidative stress index(OSI) in both groups. Schizophrenia symptoms were assessed using the positive and negative syndrome scale (PANSS). The related routine lipid profile parameters including HDL were also examined. Results: Patients had significantly higher CRP, fibrinogen, TOS and OSI levels;but the patients and control subjects did not differ on activities of the antioxidant enzymes PON1 and ARE. Interestingly, there were not any group differences in the lipid profile parameters except the triglyceride levels, that increased significantly in the patient group. Conclusions: In the present study, reporting the ARE activities besides the PON1 activities in schizophrenic patients for the first time, we showed that PON1 and ARE enzyme activities were not statistically different in patients with chronic schizophrenia. This study provides additional evidence of increased oxidative stress and inflammation in

关键词： Oxidative Stress Antioxidant Status Inflammation Paraoxonase Schizophrenia

Effect of Moisture Content and Feed Rate on Size Reduction of Pearl Millet

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Journal of Food Science and Engineering 2011年第2期1卷 93-99页

作者： S. Balasubramanian R. Sharma S. R. Vii ay Kumar Central Institute of Post Harvest Engineering and Technology Ludhiana 141004 Punjab India College of Agricultural Engineering UAS Raichur 584102 Karnataka India

Pearl millet at various moisture content （6.2, 9.4 and 12.3%, d.b.） and feed rates （3, 6 and 9 kg/h） was ground using hammer mill and its physical properties viz. arithmetic mean diameter, geometric mean diameter, thousand grain weight, aspect ratio, specific surface area, surface area and bulk density were studied. Sieve analysis results showed that the increase in moisture content produced more medium sized particles with decreased percent weight retained in pan. Bond＇s work index, Kick＇s constant and average particle size were increased with the decrease in total surface area at higher moisture levels. The highest energy （2.34 KWh/kg） was consumed for 12.3% moisture content. Various grinding characteristics were significantly affected by moisture content and feed rate either individually or in combination and correlated in terms of Bond＇s work index, Kick＇s constant, total surface area, average particle size, effectiveness of milling and bulk density. Milling loss was found to be higher at lower moisture level and decreased with the increase of moisture content as well as feed rate. The loose and compact bulk density was ranged between 46.8-199.5 kg m^-3and 53.5-254.1 kg m^-3, respectively among the entire sieve fractions. Water absorption capacity increased with the decrease in particle size,

关键词： Pearl millet grinding size reduction particle size sieve analysis hammer mill moisture content.

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新指环王宝应湖大闸蟹

美食与美酒 2013年第10期 148-155页

作者： ay 小黑(摄影)

“宝应湖大闸蟹”以其清水出芙蓉的天生丽质，在一些蟹农们斗蟹的盲品比赛上，实实在任凭味道力压群雄”、“新指环王”就此诞生。

关键词：大闸蟹指环芙蓉

土耳其Pütürge变质地体晚白垩世岩浆作用与变质作用的年代学研究(英文)

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岩石学报 2015年第5期31卷 1485-1493页

作者： ayse Didem KILI Cihat ATES Department of Geological Engineering Faculty of EngineeringFīrat University

Pütürge变质地体位于新特提斯构造带南部的土耳其Anatolia逆冲推覆构造带内,形成于欧亚板块与阿拉伯板块之间晚白垩纪碰撞造山事件。Pütürge变质地体主要由变质泥质片岩及片麻岩、花岗质片麻岩、石英岩、角闪岩和大理岩组成,发育类... 详细信息

Pütürge变质地体位于新特提斯构造带南部的土耳其Anatolia逆冲推覆构造带内,形成于欧亚板块与阿拉伯板块之间晚白垩纪碰撞造山事件。Pütürge变质地体主要由变质泥质片岩及片麻岩、花岗质片麻岩、石英岩、角闪岩和大理岩组成,发育类似巴罗型递增变质带的变质带序列,变质程度达高绿片岩相至低角闪岩相。此前该变质地体一直缺乏精确的年代学约束,为此我们采用了二次离子质谱锆石U-Pb测年方法和黑云母40Ar/39Ar测年方法,对该变质地体进行了年代学研究。结果表明,区内花岗片麻岩原岩形成于84.2±1.1Ma,变质泥质片麻岩中黑云母40Ar/39Ar年龄所代表的变质时代为83.21±0.1Ma。这说明早白垩世期间岩浆侵入事件不久,Pütürge变质地体就发生了区域变质作用。

关键词： Pütürge变质地体 U-Pb定年 40Ar/39Ar定年新特提斯土耳其

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牛海绵状脑病

国外兽医学（畜禽传染病） 1991年第4期11卷 3-5页

作者： И.А.Бayдcв

Clinical predictors of severe gallbladder complications in acute acalculous cholecystitis

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世界胃肠病学杂志：英文版 2003年第12期9卷 2821-2823页

作者： ay-Jiun Wang Tsang-En Wang Ching-Chung Lin Shee-Chan Lin Shou-Chuan Shih Division of GastrOenterology Department of Internal MedicineMackay Memorial HospitalTaipeiTaiwanChina

AIM: To evaluate the relationship between clinical information (including age, laboratory data, and sonographic findings) and severe complications, such as gangrene,perforation, or abscess, in patients with acute acalculous cholecystitis (AAC).METHODS: The medical records of patients hospitalized from January1997 to December 2002 with a diagnosis of acute cholecystitis were retrospectively reviewed to find those with AAC, confirmed at operation or by histologic examination. Data collected included age, sex, white blood cell count, AST, total bilirubin, alkaline phosphatase,bacteriology, mortality, and sonographic findings. The sonographic findings were recorded on a 3-point scale with 1 point each for gallbladder distention, gallbladder wall thickness ＞3.5 mm, and sludge. The patients were divided into 2 groups based on the presence (group A) or absence (group B) of severe gallbladder complications, defined as perforation, gangrene, or ***: There were 52 cases of AAC, accounting for 3.7% of all cases of acute cholecystitis. Males *** patients were diagnosed by ultrasonography (48 of 52) or computed tomography (17 of 52). Severe gallbladder complications were present in 27 patients (52 %, group A) and absent in 25(group B).Six patients died with a mortality of 12 %.Four of the 6 who died were in group *** in group A were significantly older than those in group A were significantly older than those in group B (mean 60.88 y vs. 54.12 y, P=0.04) and had a significantly higher white blood cell count (mean 15 885.19 vs. 9 948.40,P=0.0005). All the 6 patients who died had normal white blood cell counts with an elevated percentage of band *** most commonly cultured bacteria in both blood and bile were E. Coli and Klebsiella pneurnoniae. The cumulative sonographic points did not reliably distinguish between groups A and B, even though group A tended to have more ***: Older patients with a high white cell count are more li

关键词：急性胆囊炎并发症临床特点早期诊断急腹症

小行星／彗星巨型冲击可能触发重要的地壳演化幕

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地质科技动态 1996年第2期 41-42页

作者：格利.,ay

China’s New Development Philosophy

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China Today 2021年第7期70卷 44-46页

作者： JUAN CARLOS CAPUNay 不详

THIS year marks the first centenary of the founding of the Communist Party of China(CPC).The achievements made by China during the last 100 years are the result of the efforts of several generations of Chinese people under the leadership of the CPC,which has tasked itself with the mission to seek happiness for the Chinese people and rejuvenation for the Chinese nation since its birth.

关键词： founding Communist leadership

Comparison of Biopsy Results and Imaging Methods,in the Diagnosis of Breast Cancer

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Surgical Science 2012年第9期3卷 445-451页

作者： Mehmet Ali Eryilmaz Ozgur Oner Ahmet Okus Omer Karahan Said Bodur Serden ay Seher Civcik General Surgery Clinic Konya Training and Research HospitalKonyaTurkey Radyology Clinic Konya Training and Research HospitalKonyaTurkey Department of Public Health Meram Faculty of MedicineSelcuk UniversityKonyaTurkey Konya Early Diagnosis of Cancer-Screening and Education Center Kanser Erken Teshis-Tarama ve Egitim Merkezi(KETEM)KonyaTurkey

Purpose: In this study, we aimed at comparing the sensitivity and selectivity rates of Ultrasonography (USG), Mamography (MG) and Magnetic Resonance (MR), based on the biopsy results of breast mass lesions. Materials and methods: Between January 2009 and December 2010 in Konya Training and Research Hospital the biopsy results and reports of imaging tecniques such as USG, MG and MR, were obtained from the hospital automation. The sensitivity and selectivity of the USG, MG and MR were calculated. Results: The avarage age of the 112 patients included in this study is 49 ± 10 (23 - 71). 27 (24%) of the patients were found to have breast cancer after the histopathologic examination. USG was used with the 95 (94%) of the patients and 17 (18%) of the patients were diagnosed to have cancer. MG was used with the 75 (67%) of the patients and 15 (20%) of the patients were diagnosed to have cancer, and MR was used with the 112 (100%) of the patients and 25 (22%) of the patients were diagnosed to have cancer. In the pathologic diagnosis of cancer, the sensitivity of USG was found 85%, the sensitivity of MG was found 89%, and the sensitivity of MR was found 92%. The selectivity of these tecniques were 58%, 87% and 57% respectively. Conclusion: MR and MG have similar sensitivity rates in the diagnosis of breast cancer. Breast MR is an appropriate imaging tecnique that can be used in suitable indications in addition to USG and MG.

关键词： Breast Cancer Magnetic Resonance Mamography Ultrasonography