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内皮Notch信号的抑制阻碍脂肪酸转运并导致成年心脏的代谢和血管重塑

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中华高血压杂志 2018年第3期26卷 203-203页

作者：刘青叶鹏 jabs M Rose Aj Lehmann LH Taylor j Moll I Sijmonsma TP Herberich SE Sauer SW Poschet G Federico G Mogler C Weis EM Augustin HG Yan M Gretz N Schmid RM Adams RH Gr9ne Hj Hell R Okun jG backs j Nawroth PP Herzig S Fischer A

营养成分在被肌肉细胞代谢利用之前通过内皮细胞转运。然而,对于内皮运输过程的调节知之甚少。Notch信号传导是发育过程中代谢和血管生成的关键调控因子。在该研究中,jabs等研究了成年小鼠内皮Notch信号的遗传和药理学调控如何影响内皮... 详细信息

营养成分在被肌肉细胞代谢利用之前通过内皮细胞转运。然而,对于内皮运输过程的调节知之甚少。Notch信号传导是发育过程中代谢和血管生成的关键调控因子。在该研究中,jabs等研究了成年小鼠内皮Notch信号的遗传和药理学调控如何影响内皮脂肪酸转运、心脏血管生成和心脏功能。

关键词： Notch信号细胞转运细胞代谢心脏功能成年小鼠脂肪酸内皮血管重塑

Safe mining practices under wide spans in underground non-caving mines——Case studies

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International journal of Mining Science and Technology 2019年第4期29卷 535-540页

作者： j.j.Ran Kinross Gold Corporation

Mining under wide span is of concern as it increases the probability of back caving causing personnel injury and equipment damage in underground mines in open stoping and underhand drift-and-fill *** restricting personnel access to well supported lateral development is commonly practiced,it is not always possible to implement this requirement due to various factors such as ore loss control,drilling equipment limitations,availability of remote operating capacity and consideration of *** with rules implemented to limit personnel entry into openings with wide spans,the hazards of equipment damage and back caving still *** the years,different practices have been reported and adopted to minimize risks associated with exposure to large spans in various underground *** from these practices are beneficial to current and future mines with challenges of safe extraction of thick deposits in a non-caving *** paper briefly summarizes practices in mining wide orebodies using the open stoping method without personnel access and underhand mining using the drift-andfill method with personnel exposure in the industry and presents cases from Kinross mines where the hanging pillar design was tested,and stope backs were naturally and artificially supported for extraction under wide spans using the open stoping method.

关键词： Mine safety Wide span Back stability Underhand mining Hanging pillar

Water Striders:The Biomechanics of Water Locomotion and Functional Morphology of the Hydrophobic Surface(Insecta:Hemiptera-Heteroptera)

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journal of Bionic Engineering 2008年第2期5卷 121-126页

作者： P. j. Perez Goodwynj jin-tong Wang Zhou-ji Wang Ai-hong ji Zhen-dong Dai K. Fujisaki Institute for Bio-lnspired Structure and Surface Engineering （IBSS） Nanjing University of Aeronautics andAstronautics Nanjing 210019 P. R. China Laboratory oflnsect Ecology Graduate School of.4griculture Kyoto University Kyoto 606-8502 Japan

Water striders are insects living on the water surface, over which they can move very quickly and rarely get wetted. We measured the force of free walking in water striders, using a hair attached to their backs and a 3D strain gauge. The error was calculated by comparing force and data derived from geometry and was estimated as 13%. Females on average were stronger （1.32 mN） than males （0.87 mN）, however, the ratio of force to weight was not significantly different. Compared with other lighter species, Aquarius paludum seems stronger, but the ratio of force to weight is actually lower. A. paludum applies about 0.3 ***^-1 to 0.4 *** 1 with its mid-legs, thus avoiding penetrating the surface tension layer while propelling itself rapidly over the water surface. We also investigated the external morphology with SEM. The body is covered by effectively two layers of macro-and micro-hairs, which renders them hydrophobic. The setae are long （40 μm-60μm） and stiff, being responsible for waterproofing, and the microtrichia are much smaller （〈10μm）, slender, and flexible, holding a bubble over the body when submerged.

关键词： force surface tension aquatic insect morphology microtrichia setae

Physical Characteristics Explain Ball-Carrying Capability in Sub-Elite Rugby Union Players

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journal of Science in Sport and Exercise 2023年第3期5卷 244-253页

作者： Alexander S.Hart Robert M.Erskine Tom j.Mclaughlin David R.Clark School of Sport and Exercise Science Liverpool John Moores UniversityL33AF LiverpoolUK Ealing Trailfinders Rugby Club LondonUK Institute of Sport Exercise and HealthUniversity College LondonLondonUK

Purpose The aims of the present study were two-fold:(i)to investigate the relationship between physical characteristics and the game statistics associated with ball-carrying capability amongst sub-elite rugby union players,and(ii)to predict the level of change in these physical characteristics required to improve the associated game statistic via regression *** Thirty-eight senior professional players(forwards,n=22;backs,n=16)were assessed for body mass(BM),back squat(BS)single-repetition maximum(1RM)normalised to BM(1RM/BM),10 m sprint velocity(S10),10 m sprint momentum(SM10),and the game statistics from 22 games within the 2019/20 RFU Championship *** relationship between these measures and the predicted level of change in a physical measure required to improve the total number of the associated game statistic by one were assessed by Pearson’s correlation coefficient and simple regression *** In forwards,an~11.5%reduction in BM,an~11.8%improvement in BS 1RM/BM,or an~11.5%increase in S10 was required to improve the game statistics associated with ball-carrying *** backs,a~19.3%increase in BM or a~15.6%improvement in SM10 was *** These findings demonstrate that improvements in lower-body relative strength,acceleration performance,and position-specific alterations in body mass are required to maximise the ball-carrying capability and therefore match outcome of sub-elite rugby union players.

关键词： Speed Acceleration Momentum Strength Body mass

A Valentine to One Who Cared-Too Much

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中国翻译 1981年第5期 14-15页

作者： NANCY j.RIGG

It’s raining, again. As I lie awake in bed, lis-tening to the sound of those razor-sharp dropspounding on the pavement, my mind goes reelingdown dark corridors teeming with agonizing flash-backs, and a chill from within fills me with ***’s raining, *** does this every year in Southern California;at least that’s what they told me last year whenI marveled at the relentless determination of therain. There seem to be two seasons here. Duringthe rainy season, sometimes the storms drench thearea nonstop for days. Sometimes the storms come

关键词： Th A Valentine to One Who Cared-Too Much

Silane Modification of Starch-Based Wood Adhesive: Review

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Open journal of Polymer Chemistry 2019年第3期9卷 53-62页

作者： Ravindra V. Gadhave Praneeta Sheety Prakash A. Mahanwar Pradeep T. Gadekar Bilvesh j. Desai Department of Polymer and Surface Engineering Institute of Chemical Technology Mumbai India

Currently there has been a growing interest in substituting traditional synthetic polymers with biobased renewable polymers for adhesive applications. However, biobased renewable polymers such as starch suffer from few draw-backs like poor water resistance and mechanical strength. To become important potential alternatives of synthetic polymers, starch must have comparable physical, chemical, thermal and mechanical properties to that of synthetic polymers. To achieve this, starch has been modified by a series of crosslinkers like boric acid, citric acid, glyoxal, gluteraldehyde, etc. and silane modification. Silane modification by chloropropyl trimethoxysilane, γ-Methacryloxypropyl trimethoxy silane and vinyl trimethoxy silane is a suitable method to improve the performance in terms of mechanical and thermally. Silane forms covalent bonds with starch during starch modification resulted in enhanced shear strength and storage stability. A new research on biodegradable, renewable, environmentally friendly silane modification of starch-based wood adhesive that was prepared by reacting with various silanes. This paper, we reviewed silane as a modifying agent for starch-based wood adhesive.

关键词： Starch Silane Wood Adhesive Coupling Agents

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江豚皮肤的超微结构及其与其它豚类的比较

水生生物学报 1986年第1期10卷 8-14+103-104页

作者：刘仁俊,R.j.哈里森中国科学院水生生物研究所英国剑桥大学解剖系武汉

江豚皮肤的超微结构与海洋豚类相同,但在各层表皮细胞中存在大量的膜被颗粒,这很可能与江豚适应从海水进入淡水的生活方式有关。大量成束的张力原纤维的存在,有利于江豚在水中深潜和快速游泳,可适应来自各方面的压力,加强细胞之间的联... 详细信息

江豚皮肤的超微结构与海洋豚类相同,但在各层表皮细胞中存在大量的膜被颗粒,这很可能与江豚适应从海水进入淡水的生活方式有关。大量成束的张力原纤维的存在,有利于江豚在水中深潜和快速游泳,可适应来自各方面的压力,加强细胞之间的联接。在上下颌皮肤的乳头层基部大量被囊神经末梢和有鞘神经纤维束的分布、与江豚水底觅食方式有关。白鱀豚和条纹原海豚皮肤的超微结构与江豚大致相同,但亦有其各自的特点。

关键词： Ultrastructure membrane coating granules encapsulated nerve endings Necphocaena phocaenoides

我国高水平游泳运动员运用新规则技术的优势与不足

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成都体育学院学报 2012年第4期38卷 77-80,94页

作者：马吉光胡毛毛上海体育学院上海200438 海军游泳队上海200083

采用文献资料法、观察法对参加2011年全国游泳锦标赛和冠军赛的运动员进行观察与统计,运用调查法对部分国家队、省市专业队教练员以及国际级以上裁判员进行调查,分析我国高水平游泳运动员在技术方面运用规则的优势与不足。建议仰泳运动... 详细信息

采用文献资料法、观察法对参加2011年全国游泳锦标赛和冠军赛的运动员进行观察与统计,运用调查法对部分国家队、省市专业队教练员以及国际级以上裁判员进行调查,分析我国高水平游泳运动员在技术方面运用规则的优势与不足。建议仰泳运动员出发时提高脚的位置,从而提高身体重心位置,减少水对运动员背部、臀部的阻力,使身体在空中的抛物线更加合理;部分仰泳运动员转身过程中没有连贯划臂,使动作出现停顿;蛙泳运动员出发和转身后应充分利用水下海豚式打腿增大推进力,同时避免犯规。

关键词：高水平游泳运动员竞赛规则仰泳出发水下蝶泳打腿仰泳转身