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American Journal of.Analytical Chemistry 2015年第11期6卷 886-897页

作者： Dmitry f. Pavlov Jacques Bezuidenhout Marina V. f.ontasyeva Zoya I. Goryainova I. D. Papanin Institute of.the Biology of.Inland Waters Borok Russian Federation f.culty of.Military Science Physics Department Stellenbosch University Saldanha South Africa Joint Institute f.r Nuclear Research Moscow Region Russian Federation

contents of.23 trace elements (Sc, V, Cr, Mn, f., Co, Zn, As, Se, Br, Rb, Sr, Mo, Ag, Sb, I, ba, La, Ce, Sm, Eu, Hf. Ta) were quantitatively determined in sof. tissues and shells of.mass non-indigenous bivalve mussels—f.rmed Pacif.c oysters (Crassostrea gigas) and f.rmed and wild invasive Mediterranean mussels (Mytilus galloprovincialis) at the Atlantic coast of.South Af.ica. The study revealed that the contents of.the majority of.elements in the sof. tissues of.both species were higher than those in the shells. The tissues of.wild invasive Mediterranean mussels contain higher levels of.a range of.trace elements comparing to f.rmed mussels. The tissues of.Pacif.c oysters contain much higher levels of.almost all elements studied compared to the tissues of.Mediterranean mussels. Higher content of.zinc in the mussels and oysters f.om Saldanha bay may evidence anthropogenic pollution of.the bay’s ecosystem by this metal, which necessitates continued monitoring of.levels of.potentially toxic metals. Both alien species, and especially Pacif.c oysters, may serve as reliable biomonitors f.r trace elements in marine ecosystems. Both species are rich in essential elements and provide nutritionally-valuable seaf.ods.

关键词： Invasive Bivalve Mollusks Chemical Composition Crassostrea gigas Mytilus galloprovincialis Aquaculture Water Quality South Af.ica

Ef.ects of.Ovariectomy and 17<i>β</i>-Estradiol Replacement on Dopamine D2 Receptors in f.male Rats: Consequences on Sucrose, Alcohol, Water Intakes and Body Weight

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Journal of.Behavioral and Brain Science 2018年第1期8卷 1-25页

作者： Abdoulaye ba Seydou Silué Brahima bamba Lociné bamba Serge-Vastien Gahié Université f.lix Houphouë t-Boigny UFR Biosciences Abidjan C&ocirc te d’Ivoire

background: Mechanisms underlying overeating-induced obesity in post-menopausal woman include f.nctional lack of.17β-estradiol dysregulating dopamine D2 receptors, thereby inducing f.od addiction, glucose craving or alcohol dependence through reward circuitry. This study aimed at f.rther understanding 17β-estradiol and dopamine D2 receptors interf.rences in the etiology of.woman obesity. Method: Seventy-two Wistar f.male rats weighing 200 - 205 g, individually-housed, were divided into non-ovariectomized control (C = 6 groups) and ovariectomized rats (OVX = 6 groups) which were concurrently subjected to the f.llowing treatments: Non-drug-treated (DMSO vehicle), 17β-estradiol (E2, 5 μg/kg, s.c.), sulpiride (SUL, 20 mg/kg, i.p.), bromocriptine (BR, 0.1 mg/kg, i.p.), E2 + SUL or E2 + BR, designating the 6 constitutive groups of.either control or ovariectomy. Within each experimental group, consumption of.dif.erent solutions (10% alcohol, 10% sucrose and water) as well as f.od intake and body weight were daily measured, f.r 10 consecutive days. Results: This study indicated that D2S was a specif.c inducer of.alcohol and f.od intakes, but reduced sugar consumption. In addition, 17β- estradiol regulated the body weight set point, modulating D2S f.nctions towards increased f.od intake at lower weights and decreased f.od intake at higher weights. D2S met the slow genomic actions induced by 17β-estradiol. Conversely, D2L inhibited alcohol and f.od intakes, but induced specif.cally sugar consumption, thereby regulating blood glucose levels and promoting energy expenditure in reducing body weight. Indeed, 17β-estradiol exerted a tonic inhibition on D2L which was released by OVX, exacerbating sugar intake and increasing body weight. D2L mediated the rapid metabolic ef.ects of.17β-estradiol. Conclusion: Our results supported physiological data reporting that activation of.the mostly expressed presynaptically D2S-class autoreceptors decreased dopamine release stimulating f.od int

关键词： 17β-Estradiol Dopamine D2 Receptors Bromocriptine Sulpiride Water Sucrose Alcohol Intakes Obesity

荧光显微术与萋-尼氏染色技术在检查痰抗酸杆菌方面的比较

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国际结核病与肺部疾病杂志 2000年第Z1期 60-64页

作者： f.ba H.L.Rieder 吴雪琼 Laboratoire National de Ref.rence pour la Tuberculose Programme National de lutte contre la Tuberculose Dakar Senegal 。Tubercolosis

背景:塞内加尔达喀尔国家结核病参比实验室。目的:比较荧光显微镜和明视野显微镜检查抗酸杆菌的结果。方法:1996年1月至1998年6月期间2630份痰标本被同时制备2种涂片,在1000倍物镜下分别进行萋-尼氏染色和荧光显微术检查,并应用这两种... 详细信息

背景:塞内加尔达喀尔国家结核病参比实验室。目的:比较荧光显微镜和明视野显微镜检查抗酸杆菌的结果。方法:1996年1月至1998年6月期间2630份痰标本被同时制备2种涂片,在1000倍物镜下分别进行萋-尼氏染色和荧光显微术检查,并应用这两种方法同时检查一例标本的68张涂片来确定判断一张涂片为阴性所需的检查时间。结果:诊断和随访检查时两者的符合率分别为96.9％和92.3％。当标本中每100个视野至少10条菌时,两者的检出率相似,但当标本中每100个视野少于10条菌时,荧光显微术的检出率较高。在同倍物镜下,荧光显微术判断一张涂片为阴性所需的检查时间平均为3分34秒,而萋-尼氏染色技术需7分44秒。结论:两者的检查结果非常相似。对于含菌量少的病例,荧光显微镜似比明视野显微镜的检出率更高,而且所需检查时间少一半多。

关键词：抗酸染色金胺O 荧光显微镜结核病萋-尼氏染色

Neonatal Bilirubin Encephalopathy: Study of.30 Cases at Albert Royer National Children Hospital of.Dakar

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Open Journal of.Pediatrics 2020年第1期10卷 116-124页

作者： P. M. f.ye Y. J. Dieng I. Deme D. f. Cissé M. Kane S. R. Tcheuf.a Wekang A. Thiongane I. D. ba A. ba M. Gueye B. Niang P. S. Sow Amadou Sow Djibril Boiro N. R. Diagne-Gueye A. L. f.ll O. Ndiaye Centre Hospitalier National d’Enf.nts Albert Royer Dakar Senegal Centre Hospitalier Abass Ndao Dakar Senegal Hopital pour Enf.nts de Diamniadio Dakar Senegal

Introduction: Unconjugated bilirubin jaundice is a common symptom in neonatal period. In some babies, excessive serum bilirubin concentrations can place them at risk of.acute bilirubin encephalopathy (BE) when the unconjugated pigment crosses the blood-brain barrier. Our study aimed to describe epidemiology, diagnosis and prognosis of.BE at the Neonatology Department of.Albert Royer Children’s Hospital of.Dakar. Materials and Methods: It was a retrospective, descriptive study of.cases of.BE f.om January 1, 2015 to June 30, 2019. Obstetric and perinatal data as well as postnatal jaundice data (onset time, associated signs, signs of.encephalopathy, treatment and evolution) were collected and analyzed by SPSS sof.ware version 2.0. Almost all newborns (27 cases;90%) were exclusively breastf.d. At admission, all children exhibited blunt jaundice and signs of.encephalopathy dominated by the abolition of.archaic ref.exes (76.7%), low suction (22 cases;73.3%), central apnea (12 cases, 40%). The mean serum bilirubinemia was 322 mg/litre. Neonatal inf.ction (10 cases;33.3%) and f.tal-maternal incompatibility (16 cases;53.3%) were the main causes. All children received intensive phototherapy and exsanguino transf.sion was perf.rmed f.r 7 newborns (23.3%). Nine children died (30% mortality rate). Conclusion: Only better organisation of.perinatal care with enhanced postnatal f.llow-up can reduce the incidence of.EB.

关键词： Neonatal Hyperbilirubinemia Encephalopathy Perinatal Care

Inocybe cavalcantiae,a new species f.om northern Brazil

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Studies in f.ngi 2020年第1期5卷 1-5页

作者： Wartchow f Universidade f.deral da Paraíba Departamento de Sistemática e EcologiaJoão PessoaPBBrazil ORCID:0000-0003-4930-565X

Inocybe cavalcantiae is described based on morphological data f.om Pernambuco,Northeast *** is characterized by radially f.brillose/rimose pileus,narrow marginate bulb,nodulose basidiospores,lagenif.rm to clavate metuloids pleurocystidia and versif.rm metuloids *** species is described,illustrated and compared with morphologically similar species.

关键词： Agaricales Agaricomycetes basidiomycota Neotropic taxonomy

A Severe COVID-19 Inf.ction in Neonates: A Case Report

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Journal of.Biosciences and Medicines 2021年第12期9卷 118-123页

作者： Idrissa Demba ba Mohameth Mbodj f.tim Tall Serigne T. Ndiaye Saf.etou Dieye Mouhamed f.ttah Amadou Sow Ndeye f. Sow Awa Kane Aita Seck Aminata Mbaye Alioune M. Coundoul Khadim Bop Pape S. Sow Amadou L. f.ll Papa M. f.ye Ousmane Ndiaye Albert Royer National Children Hospital Dakar Senegal Cheikh Anta DIOP University Dakar Senegal Abass Ndao Hospital Center Dakar Senegal

Coronavirus disease (COVID-19) is a highly contagious inf.ctious disease. f.rst case was reported at the end of.2019 in China. Children and neonate population appears to be relatively f.ee of.the virus. We reported a severe and f.tal neonate case of.COVID-19 in a 22 days old neonate f.male due to the delta variant strain during the third wave outbreak. She presented with f.ver, cough, grunting and diarrhea started 5 days bef.re admission. Physical exam’s revealed severe respiratory distress, hypoxia and bilateral pulmonary condensation. PCR test f.r COVID-19 was positive. Chest X-ray f.und bilateral inf.ltrates. Chest CT showed dif.use ground glass images with 75% of.lung parenchymal involvement. She was treated with antibiotics, corticostoid, respiratory support (CPAP and oxygen). Death occurred af.er 15 days of.hospitalization in the context of.multiple organ f.ilure and pulmonary hypertension.

关键词： COVID-19 Hypoxia Newborn Variant Delta Senegal

Neonatal Ref.rences: Epidemiology and Prognosis in a Malian Context

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Open Journal of.Pediatrics 2021年第3期11卷 479-489页

作者： f.toumata L. f. Diakité Djénèba Konaté Nouhoum L. Traoré Noel banou Lala N. Sidibé Oumar Coulibaly Belco Maiga Karamoko Sacko f.usseyni Traoré Abdoul K. Doumbia Hawa G. Diall Leila Maiga Ibrahim Ahamadou Alou Traoré Adama Koné Guediouma Dembélé Djita ba-Sidibé Pierre Togo Adama Dembélé El Mouloud Cissé Abdoul A. Diakité Boubacar Togo Mariam Sylla f.toumata Dicko-Traoré Department of.Pediatrics of.the University Hospital Gabriel Toure Bamako Mali Ref.rence Health Center of.Commune IV Bamako Mali Pediatrician Doctor Practicing in Private Bamako Mali Hospital Mother-Child “Luxembourg” Bamako Mali Mali Hospital Bamako Mali Ref.rence Health Center of.Commune III Bamako Mali

Neonatal mortality remains a public health problem in Mali. The neonatal ref.rral is a systemic f.ctor determining the neonatal prognosis. This work was initiated to determine the f.equency of.neonatal ref.rrals and to determine their prognosis. Patients and Methods: A cross-sectional study was carried out from November 1, 2019 to January 31, 2020 in the neonatology service of the pediatrics department of the Gabriel Toure University Hospital in Bamako. All newborns referred by another health structure in the country were included in this stud. All newborns referred by another health structure in the country were included in this study. To determine the risk factors related to the neonatal referral, we performed univariate and multivariate analyzes to determine the odds ratios and fitted with a significant p probability if p 0.05 and the 95% confidence interval. Results: The frequency of referrals was 54.3%. Newborns came from basic structures in 19.3% of cases, from tertiary structures in 6.7%. The main reason for transfer was prematurity (40.2%) followed by perinatal anoxia (15.3%), malformations (15.3%), respiratory distress (15.2%) and infection neonatal (9.1%). The ambulance was the primary means of transfer in 71.3%.

关键词： Neonatal Ref.rences Epidemiology Prognosis Malian Context

Applications-Some Inf.uences of.Engineering Ideas on Biology Being the f.f.h in a series of.essays on the materials of.nature

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Journal of.Bionic Engineering 2006年第2期3卷 99-114页

作者： Julian f.V.Vincent Department of.Mechanical Engineering The University of BathBath BA2 7AYUK

Ideas f.om engineering have helped the understanding of.biological organisms f.r thousands of.years. However, the mechanical aspects of.biological materials and structures can, if.properly interpreted and analysed, lead to a deeper understanding of.the biology of.organisms. Such an approach, although always current in some f.rm, is nevertheless subject to the vagaries of.f.shion and the availability of.analytical techniques. At present we are in a period of.upturn. Areas of.interest are deployable structures （applications in aerospace）, palaeontology （how little do we need to know in order to create a credible biosphere） and f.od science （we need a rational approach to the mechanics of.f.od）.

关键词： Applications-Some Inf.uences of.Engineering Ideas on Biology Being the f.f.h in a series of.essays on the materials of.nature

养阴化纤方对肺纤维化大鼠TNf.α、内皮素-1和羟脯氨酸水平的影响

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郑州大学学报（医学版） 2010年第4期45卷 623-626页

作者：巴艳郑州大学第一附属医院中医科郑州450052

目的:探讨养阴化纤方对博莱霉素致大鼠肺纤维化的作用及机制。方法:选取雄性SD大鼠60只,随机分为正常对照组、模型对照组、阳性对照组、高剂量治疗组和低剂量治疗组5组,每组12只;后4组用盐酸博莱霉素建立大鼠肺纤维化模型,高剂量治疗组... 详细信息

目的:探讨养阴化纤方对博莱霉素致大鼠肺纤维化的作用及机制。方法:选取雄性SD大鼠60只,随机分为正常对照组、模型对照组、阳性对照组、高剂量治疗组和低剂量治疗组5组,每组12只;后4组用盐酸博莱霉素建立大鼠肺纤维化模型,高剂量治疗组和低剂量治疗组分别灌服养阴化纤方药20和10g/kg,阳性对照组灌服等体积的地塞米松,正常对照组灌服等体积的生理盐水;灌药后第7和28天,分别检测大鼠支气管肺泡灌洗液肿瘤坏死因子-α(TNf.α)、内皮素(ET-1)和肺组织羟脯氨酸(HYP)的水平,同时观察肺组织形态学变化。结果:5组间TNf.α、ET-1和HYP水平比较,差异均有统计学意义(第7天:f.分别为36.823、12.064和51.979,P均f.分别为23.484、19.600和33.631,P均f.α、ET-1和HYP水平均高于正常对照组(P均f.α、ET-1和HYP水平均低于模型对照组(P均f.α、ET-1和HYP的水平而达到防治肺纤维化的效应。

关键词：养阴化纤方肺纤维化肿瘤坏死因子-α 内皮素-1 羟脯氨酸大鼠

The“Wolf.Is Indeed Coming:Recombinant“Deltacron”SARS-CoV-2 Detected

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China CDC weekly 2022年第14期4卷 285-287页

作者： Liang Wang George f.Gao CAS Key Laboratory of.Pathogen Microbiology and Immunology Institute of MicrobiologyCenter for Influenza Research and Earlywarning(CASCIRE)CAS-TWAS Center of Excellence for Emerging Infectious Diseases(CEEID)Chinese Academy of SciencesBeijingChina University of.Chinese Academy of.Sciences BeijingChina

The Emergence of.Deltacron”On March 9,2022,researchers f.om the Institut Pasteur used the global data science initiative GISAID(1-3)to release a severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)genome(ID:EPI_ISL_10819657)f.om an isolated virus and announced that it was the f.rst solid evidence f.r a recombinant strain f.om 2 types of.variants of.concern(VOCs)of.SARS-CoV-2(lineage AY.4 and ba.1,belonging to Delta and Omicron,respectively).

关键词： acute respiratory Delta