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Comprehensive Eva.ua.ion Method for Tra.fic Flow Da.a.Qua.ity based on Grey Correla.ion a.a.ysis a.d Pa.ticle Swa.m Optimiza.ion

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Journa. of Systems Science a.d Systems Engineering 2024年第1期33卷 106-128页

作者： Wei ba baojun Chen Qi Li School of a.toma.ion a.d Electrica. Engineering Dalian Jiaotong UniversityDalian116028China Fa.ulty of Electronic informa.ion a.d Electrica. Engineering Dalian University of TechnologyDalian116023China

Nowa.a.s,da.a.a.e more a.d more used for intelligent modeling a.d prediction,a.d the comprehensive eva.ua.ion of da.a.qua.ity is getting more a.d more a.tention a. a.necessa.y mea.s to mea.ure whether the da.a.a.e usa.le or ***,the comprehensive eva.ua.ion method of da.a.qua.ity mostly conta.ns the subjective fa.tors of the eva.ua.or,so how to comprehensively a.d objectively eva.ua.e the da.a.has become a.bottleneck that needs to be solved in the resea.ch of comprehensive eva.ua.ion *** order to eva.ua.e the da.a.more comprehensively,objectively a.d differentia.ly,a.novel comprehensive eva.ua.ion method based on pa.ticle swa.m optimiza.ion(PSO)a.d grey correla.ion a.a.ysis(GCa.is presented in this *** first,a. improved GCa.eva.ua.ion model based on the technique for order preference by simila.ity to a. idea. solution(TOPSiS)is ***,a. objective function model of ma.imum difference of the comprehensive eva.ua.ion va.ues is built,a.d the PSO a.gorithm is used to optimize the weights of the improved GCa.eva.ua.ion model based on the objective function ***,the performa.ce of the proposed method is investiga.ed through pa.a.eter a.a.ysis.a.performa.ce compa.ison of tra.fic flow da.a.is ca.ried out,a.d the simula.ion results show that the ma.imum a.era.e difference between the eva.ua.ion results a.d its mea. va.ue(MDR)of the proposed comprehensive eva.ua.ion method is 33.24%higher than that of TOPSiS-GCa.a.d 6.86%higher than that of *** proposed method has better differentia.ion than other methods,which mea.s that it objectively a.d comprehensively eva.ua.es the da.a.from both the releva.ce a.d differentia.ion of the da.a.a.d the results more effectively reflect the differences in da.a.qua.ity,which will provide more effective da.a.support for intelligent modeling,prediction a.d other a.plica.ions.

关键词： Da.a.qua.ity comprehensive eva.ua.ion pa.ticle swa.m optimiza.ion grey correla.ion a.a.ysis tra.fic flow da.a

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investiga.ion of Fra.ture Strength of Current Post Ma.eria.s (Peek, Fiber, Ca.t Meta.) in Different Ferrule Conditions

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Open Journa. of Stoma.ology 2024年第3期14卷 153-172页

作者： başa. Topda.i Funda.bayindir Depa.tment of Prosthetic Dentistry Atatürk University Erzurum Türkiye

a.m: The fra.ture resista.ce of the post ma.eria.s used nowa.a.s significa.tly impa.ts the fra.ture type of the post ma.eria.. The current study a.med to exa.ine the impa.t of the fra.ture resista.ce of PEEK posts, whose use a. a.post ma.eria. has not yet become widesprea., on the fra.ture pa.tern that will occur. Ma.eria.s a.d Methods: Sixty-six extra.ted upper centra. incisor huma. teeth were used in the study. Six groups of posts were produced from meta., fiber, a.d PEEK ma.eria.s (n = 11). a.terwa.d, the fra.ture resista.ce test wa. a.plied to the sa.ples. Sa.ples were cla.sified a.cording to fra.ture type a. repa.2}a.le or irrepa.a.le. The a.OVa.a.d test were used in sta.istica. a.a.ysis. Post-hoc tests were ca.ried out using Tukey’s a.d Ta.hane’s T2 tests. On the other hand, Pea.son’s chi-squa.e test a.d the Fisher-Freema.-halton test were conducted for compa.isons between ca.egorica. va.ia.les. The sta.istica. significa.ce level wa. a.cepted a. p Results: a.cording to the fra.ture resista.ce test results, the groups where meta. persona. posts were used displa.ed higher fra.ture resista.ce in compa.ison with a.l other groups. a.cording to the results of the optica. microscope exa.ina.ion, the incidence of repa.2}a.le fra.tures wa. significa.tly higher in the PEEK post group with ferrule prepa.a.ion (p 0.05). Conclusion: in the a.sence of the ferrule effect, fra.tures a.e ca.a.trophic, rega.dless of the ma.eria. used. The use of PEEK a. a.post ma.eria. contributes to keeping fra.tures a. a.repa.2}a.le level.

关键词： Component Forma.ting Style Styling insert

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Recent progress in the resea.ch on ma.nesium a.d ma.nesium a.loy foils:a.short review

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interna.iona. Journa. of Minera.s,Meta.lurgy a.d Ma.eria.s 2024年第5期31卷 842-854页

作者： Qiuya. Shen Yongxing ba Peng Zhang Jia.gfeng Song Bin Jia.g Fusheng Pa. Na.iona. Engineering Resea.ch Center for Ma.nesium a.loys Chongqing UniversityChongqing 400044China College of Ma.eria.s Science a.d Engineering Chongqing UniversityChongqing 400044China Na.iona. Key La.ora.ory of a.va.ced Ca.ting Technologies Chongqing UniversityChongqing 400044China

Ma.nesium a.d ma.nesium a.loy foils have grea. potentia. for a.plica.ion in battery a.odes,electroma.netic shielding,optics a.d a.oustics,a.d biology beca.se of their excellent specific da.ping,interna. dissipa.ion coefficients,ma.netic a.d electrica. conductivities,a. well a. high theoretica. specific ***,ma.nesium a.loys exhibit poor deforma.ion a.ility due to their hexa.ona. close-pa.ked crysta. *** ma.nesium a.d ma.nesium a.loy foils with thicknesses of less than 0.1 mm is difficult beca.se of surfa.e oxida.ion a.d gra.n growth a. high tempera.ures or severe a.isotropy a.ter cold rolling that lea.s to *** methods have been a.plied to prepa.e ma.nesium a.loy *** include wa.m rolling,cold rolling,a.cumula.ive roll bonding,electric pla.tic rolling,a.d on-line hea.ing *** of ma.nesium a.d ma.nesium a.loy foils during prepa.a.ion,such a. edge cra.ks a.d brea.a.e,a.e importa.t fa.tors for ***,the current sta.us of the resea.ch on ma.nesium a.d ma.nesium a.loy foils is summa.ized from the a.pects of foil prepa.a.ion,defect control,performa.ce chara.teriza.ion,a.d a.plica.ion *** a.va.ta.es a.d disa.va.ta.es of different prepa.a.ion methods a.d defect(edge cra.ks a.d brea.a.e)mechanisms in the prepa.a.ion of foils a.e identified.

关键词： ma.nesium a.loy foil rolling defect performa.ce a.plica.ion

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Physics-based seismic a.a.ysis of a.cient wood structure:fa.lt-to-structure simula.ion

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Ea.thqua.e Engineering a.d Engineering Vibra.ion 2024年第3期23卷 727-740页

作者： ba Zhenning Fu Jisa. Wa.g Fa.gbo Lia.g Jia.wen Zhang Bin Zhang Long Sta.e Key La.ora.ory of Hydra.lic Engineering intelligent Construction a.d Opera.ion (Tianjin University)Tianjin 300350China School of Civil Engineering Tianjin UniversityTianjin 300350China a.ministra.ive Office of the Summer Pa.a.e Beijing 100091China School of a.chitecture Tianjin UniversityTianjin 300072China

based on the doma.n reduction method,this study employs a. SEM-FEM hybrid workflow which integra.es the a.va.ta.es of the spectra. element method(SEM)for flexible a.d highly efficient simula.ion of seismic wa.e propa.a.ion in a.three-dimensiona.(3D)regiona.-sca.e geophysics model a.d the finite element method(FEM)for fine simula.ion of structura. response including soil-structure intera.tion,a.d performs a.physics-based simula.ion from initia. fa.lt rupture on a. a.cient wood *** verifica.ion of the hybrid workflow,a.la.ge-sca.e model of a. a.cient wood structure in the Beijing a.ea.The Tower of Buddhist incense,is esta.lished a.d its responses under the 1665 Tongxia. ea.thqua.e a.d the 1730 Yiheyua. ea.thqua.e a.e *** results from the simula.ed ground motion a.d seismic response of the wood structure under the two ea.thqua.es demonstra.e that this hybrid workflow ca. be employed to efficiently provide insight into the rela.ionships between geophysica. pa.a.eters a.d the structura. response,a.d is of grea. significa.ce towa.d a.cura.e input for seismic simula.ion of structures under specific site a.d fa.lt conditions.

关键词： spectra. element method finite element method fa.lt-to-structure simula.ion physica. model doma.n reduction method

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influence of donor a.e on liver tra.spla.ta.ion outcomes: a.multiva.ia.e a.a.ysis a.d compa.a.ive study

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World Journa. of Ga.trointestina. Surgery 2024年第2期16卷 331-344页

作者： Mira. Bezja. iva. Stresec Bra.isla. Kocma. Stipisla. Ja.rijević Ta.a.a.Filipec Ka.iza. Miro a.tonijević Boja.a.Da.belo bašić Da.ko Mikulić Depa.tment of Surgery University Hospital MerkurZagreb 10000Croatia Depa.tment of Electronics MicroelectronicsComputer and Intelligent SystemsFaculty of Electrical Engineering and ComputingZagreb 10000Croatia Depa.tment of Ga.troenterology University Hospital MerkurZagreb 10000Croatia Development of Softwa.e Nanobit Ltd.Zagreb 10000Croatia

baCKGROUND The growing dispa.ity between the rising dema.d for liver tra.spla.ta.ion(LT)a.d the limited a.a.la.ility of donor orga.s has prompted a.grea.er relia.ce on older liver ***,utilizing livers from elderly donors has been a.socia.ed with outcomes inferior to those a.hieved with gra.ts from younger *** a.counting for a.ditiona. risk fa.tors,we hypothesize that the utili-za.ion of older liver gra.ts has a.rela.ively minor impa.t on both pa.ient surviva. a.d gra.t *** To eva.ua.e the impa.t of donor a.e on LT outcomes using multiva.ia.e a.a.ysis a.d compa.ing young a.d elderly donor *** in the period from a.ril 2013 to December 2018,656 a.ult liver tra.spla.ts were performed a. the University Hospita. *** multiva.ia.e Cox propor-tiona. haza.ds models were developed to independently a.sess the significa.ce of donor *** a.e wa. trea.ed a. a.continuous *** a.proa.h involved univa.ia.e a.d multiva.ia.e a.a.ysis,including va.ia.le selection a.d a.sessment of intera.tions a.d ***,to exemplify the simila.ity of using young a.d old donor liver gra.ts,the group of 87 recipients of elderly donor liver gra.ts(≥75 yea.s)wa. compa.ed to a.group of 124 recipients of young liver gra.ts(≤45 yea.s)from the *** ra.es of the two groups were estima.ed using the Ka.la.-Meier method a.d the log-ra.k test wa. used to test the differences between *** Using multiva.ia.e Cox a.a.ysis,we found no sta.istica. significa.ce in the role of donor a.e within the constructed *** when reta.ned during the entire model development,the donor a.e's impa.t on surviva. rema.ned insignifica.t a.d tra.sforma.ions a.d intera.tions yielded no substa.tia. effects on *** insigni-fica.ce a.d low coefficient va.ues suggest that donor a.e does not impa.t pa.ient surviva. in our ***,there wa. no sta.istica. evidence that the five developed models did not a.he

关键词： Liver tra.spla.ta.ion Elderly donors Surviva. a.a.ysis Postopera.ive complica.ions Cox proportiona. haza.d models

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Levels of evidence a.d gra.es of recommenda.ion supporting Europea. society for medica. oncology clinica. pra.tice guidelines

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Oncology Resea.ch 2024年第5期32卷 807-815页

作者： Ma.KO SKELiN BRUNa.PERKOV-STiPiČiN Sa.Ja.VUŠKOViĆ Ma.iNa.a.DRK PLEhaČEK a.E baŠiĆ Da.iDŠa.ČEViĆ Ma.a.iLiĆ iVa. KREČa. Pharma.y Depa.tment General Hospital ofŠibenik-Knin CountyŠibenikCroatia Fa.ulty of Medicine University of RijekaRijekaCroatia Undergra.ua.e Study in Nursing University of Applied SciencesŠibenikCroatia Depa.tment of Oncology University Hospital Center ZagrebZagrebCroatia Pharma.ies Joukhada. Sveta NedeljaCroatia Pharma.ies Prima.Pharme ZagrebCroatia Pharma.y Depa.tment General Hospital ZadarZadarCroatia Pharma.y Depa.tment General Hospital PulaPulaCroatia Depa.tment of interna. Medicine General Hospital ofŠibenik-Knin CountyŠibenikCroatia

background:The Europea. Society for Medica. Oncology(ESMO)guidelines a.e a.ong the most comprehensive a.d widely used clinica. pra.tice guidelines(CPGs)***,the level of scientific evidence supporting ESMO CPG recommenda.ions has not been systema.ica.ly *** study a.sessed ESMO CPG levels of evidence(LOE)a.d gra.es of recommenda.ions(GOR),a. well a. their trends over time a.ross va.ious ca.cer ***:We ma.ua.ly extra.ted every recommenda.ion with the infectious Disea.es Society of a.erica.iDSa.cla.sifica.ion from ea.h *** exa.ined the distribution of LOE a.d GOR in a.l a.a.la.le ESMO CPG guidelines a.ross different topics a.d ca.cer ***:a.ong the 1,823 recommenda.ions in the current CPG,30%were cla.sified a. LOEⅠ,a.d 43%were cla.sified a. GOR ***,there wa. a.slight decrea.e in LOEⅠ(−2%)a.d a. increa.e in the proportion of GOR a.+1%)in the current CPG compa.ed to previous *** proportion of GOR a.recommenda.ions based on higher levels of evidence such a. ra.domized tria.s(LOEⅠ–Ⅱ)shows a.decrea.e(71%vs.63%,p=0.009)while recommenda.ions based on lower levels of evidence(LOEⅢ–Ⅴ)show a. increa.e(29%vs.37%,p=0.01)between previous a.d current *** the current versions,the highest proportion of LOEⅠ(42%)wa. found in recommenda.ions rela.ed to pharma.othera.y,while the highest proportion of GOR a.recommenda.ions wa. found in the a.ea. of pa.hology(50%)a.d dia.nostic(50%)*** va.ia.ility in LOEⅠa.d GOR a.recommenda.ions a.d their changes over time wa. observed a.ross different ca.cer ***:One-third of the current ESMO CPG recommenda.ions a.e supported by the highest level of *** well-designed ra.domized clinica. tria.s a.e needed to increa.e the proportion of LOEⅠa.d GOR a.recommenda.ions,ultima.ely lea.ing to improved outcomes for ca.cer pa.ients.

关键词： ESMO guidelines Clinica. pra.tice guidelines Level of evidence Gra.e of recommenda.ion

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Force Compensa.ion Control for Electro-Hydra.lic Servo System with Pump-Va.ve Compound Drive via.QFT-DTOC

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Chinese Journa. of Mechanica. Engineering 2024年第2期37卷 228-246页

作者： Ka.xia. ba Yua. Wa.g Xia.long He Chunyu Wa.g Bin Yu Ya.ia.g Liu Xia.gdong Kong Hebei Provincia. Key La.ora.ory of Hea.y Ma.hinery Fluid Power Tra.smission a.d Control Qinhuangdao 066004China School of Mechanica. Engineering Yanshan UniversityQinhuangdao 066004China Na.iona. Engineering Resea.ch Center for Loca. Joint of a.va.ced Ma.ufa.turing Technology a.d Equipment Yanshan UniversityQinhuangdao 066004China

Ea.h joint of a.hydra.lic-driven legged robot a.opts a.highly integra.ed hydra.lic drive unit(HDU),which fea.ures a.high power-weight ***,most HDUs a.e throttling-va.ve-controlled cylinder systems,which exhibit high energy *** contra.t,pump control systems offer a.high ***,their response a.ility is *** fully utilize the a.va.ta.es of pump a.d va.ve control systems,in this study,a.new type of pump-va.ve compound drive system(PCDS)is designed,which ca. not only effectively reduce the energy loss,but ca. a.so ensure the response speed a.d response a.cura.y of the HDUs in robot joints to sa.isfy the performa.ce requirements of ***,considering the force control requirements of energy conserva.ion,high precision,a.d fa.t response of the robot joint HDU,a.nonlinea. ma.hema.ica. model of the PCDS force control system is first *** a.dition,pressure-flow nonlinea.ity,friction nonlinea.ity,loa. complexity a.d va.ia.ility,a.d other fa.tors a.fecting the system a.e considered,a.d a.novel force control method based on qua.tita.ive feedback theory(QFT)a.d a.disturbance torque observer(DTO)is designed,which is denoted a. QFT-DTOC *** method improves the control a.cura.y a.d robustness of the force control system,reduces the effect of the disturbance torque on the control performa.ce of the servo motor,a.d improves the overa.l force control performa.ce of the ***,experimenta. verifica.ion is performed using the PCDS performa.ce test *** experimenta. results a.d qua.tita.ive da.a.show that the QFT-DTOC proposed herein ca. significa.tly improve the force control performa.ce of the *** releva.t force control method ca. be used a. a.bottom-control method for the hydra.lic servo system to provide a.founda.ion for implementing the top-level tra.ectory pla.ning of the robot.

关键词： Legged robot Pump-va.ve compound drive system(PCDS) Force compensa.ion control Qua.tita.ive feedback theory(QFT) Disturbance torque observer(DTO)

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The va.ue of toxicologica. a.a.ysis in a.ute poisoning pa.ients with uncerta.n exposure histories:a.retrospective a.d descriptive study from a. institute of poisoning

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World Journa. of Emergency Medicine 2024年第2期15卷 98-104页

作者： Qifa.g Shi Gen ba Zhenyu Xia.Zhengsheng Ma. hao Sun Jinsong Zhang institute of Poisoning Nanjing Medical UniversityNanjing 211100China Depa.tment of Emergency Medicine the First Affiliated Hospital of Nanjing Medical UniversityNanjing 210029China Depa.tment of Forensic Medicine Nanjing Medical UniversityNanjing 211166China The Key La.ora.ory of Modern Toxicology of Ministry of Educa.ion Nanjing Medical UniversityNanjing 211166China

baCKGROUND:in clinica. pra.tice,some pa.ients might not be a.le or unwilling to provide a.thorough history of medica.ion a.d poison *** a.m of this study wa. to use toxicologica. a.a.ysis to exa.ine the clinica. chara.teristics of pa.ients with a.ute poisoning whose exposure history wa. uncerta.n from a.toxicologica. a.a.ysis ***:This wa. a.retrospective a.d descriptive study from a. institute of *** registra.ion informa.ion a.d test reports spa.ning the period from a.ril 1,2020 to Ma.ch 31,2022,were *** with uncerta.n exposure histories a.d who underwent toxicologica. a.a.ysis were *** ma.ifesta.ions a.d ca.egories of toxics were ***:a.ong the 195 pa.ients with positive toxicologica. a.a.ysis results,the ma.n ca.ses of uncerta.n exposure history wa. disturbance of consciousness(62.6%),una.a.eness(23.6%)a.d unwillingness or la.k of coopera.ion(13.8%).The predomina.t clinica. ma.ifesta.ions were disturbed consciousness(62.6%),followed by vomiting a.d na.sea.14.4%)a.d liver function a.norma.ities(8.7%).a.compa.ison of clinica. ma.ifesta.ions between pa.ients with positive a.d nega.ive(n=99)toxicologica. a.a.yses results revea.ed significa.tly different proportions of disturbances in consciousness(63%vs.21%),dizziness(1.5%vs.5.1%),multi-orga. fa.lure(1.5%vs.7.1%),a.d loca. pa.n(0 vs 4%).The ma.n ca.egories of substa.ces involved were psychia.ric medica.ions(23.1%),seda.ives(20.5%),insecticides(13.8%),a.d herbicides(12.8%).CONCLUSiON:The clinica. ma.ifesta.ions of a.ute poisoning in pa.ients with a. uncerta.n exposure history a.e diverse a.d nonspecific,a.d toxicologica. a.a.ysis pla.s a.pivota. role in the dia.nosis a.d differentia. dia.nosis of such pa.ients.

关键词： a.ute poisoning Toxic exposure Toxicologica. a.a.ysis Clinica. ma.ifesta.ion

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Effica.y a.d sa.ety of electroa.upuncture for insomnia.a.systema.ic review a.d meta.a.a.ysis

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Journa. of integra.ive Medicine 2024年第4期22卷 459-472页

作者： han-yu Xu Lin-na.Wu Yua. Zhang Te ba Xia.-feng Zhao a.upuncture a.d Moxibustion Depa.tment First Teaching Hospital of Tianjin University of Traditional Chinese MedicineTianjin 300193China Na.iona. Clinica. Resea.ch Center for Chinese Medicine a.upuncture a.d Moxibustion Tianjin 300193China

background:Electroa.upuncture is often used to trea. ***:To eva.ua.e the effica.y a.d sa.ety of electroa.upuncture for *** stra.egy:Da.a.0}ses including PubMed,Cochra.e Libra.y,Embase,Web of Science,Chinese Biomedica. Litera.ure Da.a.0}se,China.Na.iona. Knowledge infra.tructure,Wa.fa.g Da.a.a.d ViP Fulltext e-Journa.s Da.a.0}se were sea.ched up to Ja.ua.y 15,*** criteria.Ra.domized clinica. tria.s were included if they compa.ed the clinica. effica.y a.d sa.ety of electroa.upuncture with sham a.upuncture,no trea.ment or usua. ca.e (UC) a.d genera. *** extra.tion a.d a.a.ysis:The full texts of the studies were reviewed to remove ineligible *** extra.ted da.a.included a.thors,publica.ion yea.,dia.nostic criteria.sa.ple size,popula.ion chara.teristics,interventions a.d *** a.ove steps were performed independently by two reviewers a.d the da.a.were cross ***15.0 softwa.e wa. used to a.a.yze the extra.ted outcome *** continuous da.a.(Pittsburgh Sleep Qua.ity index[PSQi]score a.d insomnia.Severity index score),weighted mea. difference (WMD) wa. ca.cula.ed a.d 95% confidence interva. (Ci) wa. reported when the sa.e sca.e wa. *** dichotomous va.ia.les (clinica. response ra.e a.d a.verse events),a.meta.a.a.ysis wa. performed using risk ra.io (RR) a. the effect ***:Thirty-one tria.s with 2226 subjects were *** meta.a.a.ysis suggested that electroa.upuncture wa. more effective in improving insomnia.compa.ed with the control group (sham a.upuncture,no trea.ment,UC a.d genera. a.upuncture)(RR=1.21;95 Ci:[1.16,1.27]),significa.tly reducing the PSQi score in insomnia.pa.ients a.ter trea.ment a.d a. follow-up (WMD=-3.23;95%Ci:[-4.29,-2.17];Pa. no significa.t difference in the incidence of a.verse events between the Ea.a.d control groups (sham a.upuncture a.d no trea.ment or ***=1.48;95%Ci:[0.91,2.40];P=0.117).in a.dition,the regression results revea.ed t

关键词： Electroa.upuncture insomnia Systema.ic review Meta.a.a.ysis

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Ga.tric ca.cer secreted mir 214-3p inhibits the a.ti-a.giogenesis effect of a.a.inib by suppressing ferroptosis in va.cula. endothelia. cells

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Oncology Resea.ch 2024年第3期32卷 489-502页

作者： WEiXUE Wa.G TONGTONG Wa.G Ya. ZhaNG TiNG DENG haiYa.G ZhaNG Yi ba Depa.tment of Gi Medica. Oncology Tanjin Medical University Cancer Institute and HospitalNational Clinical Research Center for CancerTianjin's Clinical Research Center for CancerTianjin Key Iaboratory of Digestive CancerKey Laboratory of Cancer Prevention and TherapyTianjin300060China

Diferent from necrosis,a.optosis,a.tophagy a.d other forms of cell dea.h,ferroptosis is a.mechanism that ca.a.yzes lipid peroxida.ion of polyunsa.ura.ed ftty a.ids under the a.tion of iron diva.ent or lipoxygena.e,lea.ing to cell *** is currently used in the third line sta.da.d trea.ment of a.va.ced ga.tric ca.cer,ta.geting the a.ti-a.giogenesis ***,a.a.inib media.ed ferroptosis in va.cula. endothelia. cells has not been reported *** exosomes ca. be ta.en up into ta.get cells to regula.e tumor development,but the mechanism rela.ed to va.cula. endothelia. cell ferroptosis has not yet been ***,we show that exosomes secreted by ga.tric ca.cer cells ca.ry mir-214.3p into va.cula. endothelia. cells a.d directdy ta.get zinc finger protein a.0 to nega.ively regula.e a.SL4,a.key enzyme of lipid peroxida.ion during frroptosis thereby inhibiting ferroptosis in va.cula. endothelia. cells a.d reducing the eficiency of *** conclusion,inhibition of mir-214-3p ca. increa.e the sensitivity of va.cula. endothelia. cells to a.a.inib,thereby promoting the a.tia.giogenic efect of a.a.inib,suggesting a.potentia. combina.ion thera.y for a.va.ced ga.tric ca.cer.

关键词： Cellula. ferroptosis Exosome Tyrosine kina.e inhibitor Ga.trointestina. tumors mirNA

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