检索结果-南通市图书馆

Erratum to Treatment strategies for patients with HER2-positive gastric cancer

在线全文

学校读者我要写书评

暂无评论

Cancer Biology & Medicine 2024年第3期21卷 F0003-F0003页

作者： Feixue Wang Yi ba Department of GI Medical Oncology Tianjin Medical University Cancer Institute and HospitalNational Clinical Research Center for CancerTianjin's Clinical Research Center for CancerTianjin Key Laboratory of Digestive CancerKey Laboratory of Cancer Prevention and TherapyTianjin Medical UniversityTianjin 300060China Department of Medical Oncology Department of Cancer CenterPeking Union Medical College HospitalChinese Academy of Medical SciencesBeijing 100032China

For the affiliation information,the affiliation for author Feixue Wang should be Department of GI Medical Oncology,Tianjin Medical University Cancer Institute and Hospital,National Clinical Research Center for Cancer,Tianjin's Clinical Research Center for Cancer,Tianjin Key Laboratory of Digestive Cancer,Key Laboratory of Cancer Prevention and Therapy,Tianjin Medical University,Tianjin 300060,China.

关键词： Cancer Clinical Medical

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

中日韩合作的发展、困境与前景

国际问题研究 2024年第1期 110-129,134页

作者：巴殿君左天全吉林大学东北亚研究中心吉林大学东北亚研究院

自1999 年举行首次领导人会晤以来,中日韩在内生需求、政治引领和外部危机的共同驱动下,逐渐形成“峰会-部长级-工作级” 三级合作模式,不断深化各领域合作,持续拓展在中日韩自贸区设想和“RCEP+”框架等多种路径下的合作。同时,中日韩... 详细信息

自1999 年举行首次领导人会晤以来,中日韩在内生需求、政治引领和外部危机的共同驱动下,逐渐形成“峰会-部长级-工作级” 三级合作模式,不断深化各领域合作,持续拓展在中日韩自贸区设想和“RCEP+”框架等多种路径下的合作。同时,中日韩合作的发展也面临严峻的现实困境,包括美国干扰牵制增强、合作收益预期受损、集体认同缺失等一系列问题。尽管如此,中日韩合作有深厚的民意基础和显著的政治意愿,仍存发展潜力。为更有效把握中日韩合作的回暖势头,三国应致力于深化沟通交流,调适相互认知;扩大共同利益,增强相互依赖;加强战略协作,实现机制对接。历史经验证明,三国相互影响、彼此互动, 是促进地区稳定与繁荣的核心变量;三国和平共处,合力促进地区经济发展、文化融合,符合三方国家利益与地区合作需求,也是东北亚地区合作共赢、构建和平与稳定东亚的前提条件。

关键词：中日韩合作区域一体化东北亚秩序

Respiratory Flow Rates of Metal Welders Compared to a Population Not Exposed to Metal Welding Dust

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

Open Journal of Respiratory Diseases 2024年第2期14卷 51-59页

作者： Robert Faomowe Foko Abdou Khadir Sow Awa ba.Mor Diaw Fatoumata ba. Mame Saloum Coly Absa Lam Cheikh Diop Aminata Toure Abdoulaye ba.Abdoulaye Samb Arame Mbengue Mathilde Cabral Mamadou Fall Laboratory of Toxicology and Hydrology Faculty of Medicine Pharmacy and Odontostomatology Cheikh Anta Diop University of Dakar Dakar-Fann Senegal Laboratory of Physiology and Functional Exploration Faculty of Medicine Pharmacy and Odontostomatology Cheikh Anta Diop University of Dakar Dakar-Fann Senegal Laboratory of Physiology and Functional Exploration Alioune DIOP University of Bambey Bambey Senegal Laboratory of Physiology UFR of Health Sciences Functional Exploration Department Thies Regional Hospital Center Thies Senegal

ba.kground: The welding trade includes many industrial activities in both the formal and informal sectors. Workers in this professional environment do not have access to individual and collective means of protection adapted to the activity, which exposes them to the dust emitted during their activity and therefore contributes to increasing the risk of developing respiratory disorders in this population. Objective: Our study aimed to evaluate the ventilatory function of metal welders in the city of Dakar. Method: This was a comparative study ba.ed on the analysis of the spirometric parameters of metal welders working in the city of Dakar (Senegal) with those of a control group of the same kind, selected from the general population. Measurements of forced expiratory volume in the first second (FEV1), forced vital capacity (FVC), peak expiratory flow (PEF) and maximum mid expiratory flow (MMEF) were measured. Results: A total of 75 men between the ages of 19 and 61 were recruited and divided into two groups (43 controls and 32 welders). The welding population had more frequent distal and central obstructions and pulmonary restriction compared to the control group. The metals most commonly used by welders were aluminum for welders who had an obstruction, while for those who had a restriction, iron was the most used metal. Signs of metal fever were frequently found in welders, especially those with ventilatory disorders. Conclusion: The prevalence of respiratory disorders observed is close to that observed in industrial environments, where exposure levels are the highest. The lack of personal protective equipment could also be a significant risk factor in the development of these disorders.

关键词： Welder Occupational Exposure Spirometric Disorder Metal Fever Dakar

硅谷银行破产、声誉风险跨国传染与股价异动——来自中国A股上市银行的证据

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

投资研究 2024年第6期43卷 4-21页

作者：邵磊巴曙松天津财经大学金融学院北京大学汇丰金融研究院

本文在对硅谷银行破产事件前因后果进行梳理的基础上,首次运用事件研究法将硅谷银行破产所引发声誉风险对A股上市银行的影响及其异质性进行识别和检验。研究发现,该影响确实存在且异质性明显。具体而言:中国国有大型银行所受到声誉风险... 详细信息

本文在对硅谷银行破产事件前因后果进行梳理的基础上,首次运用事件研究法将硅谷银行破产所引发声誉风险对A股上市银行的影响及其异质性进行识别和检验。研究发现,该影响确实存在且异质性明显。具体而言:中国国有大型银行所受到声誉风险竞争效应的影响远高于传染效应,投资者对其信心增强。与之相反,区域性农商行与城商行受到的负面冲击幅度最大也最为严重,呈现出显著的声誉风险传染效应。全国性股份制银行的表现介于二者之间。

关键词：银行破产声誉风险股票市场事件研究法

Nanomaterials for refining tumor microenvironment and enhancing therapy in head and neck squamous cell carcinoma: a review

在线全文

学校读者我要写书评

暂无评论

Oncology and Translational Medicine 2024年第4期10卷 151-161页

作者： Kaifeng Zheng Ruibiao Song Ruifeng Li Mengli Liu Yunpeng ba.Wei Jiang Kelong Fan Department of Rhinology The First Affiliated Hospital of Zhengzhou UniversityZhengzhouHenanChina Application Center for Precision Medicine Academy of Medical SciencesZhengzhou UniversityZhengzhouHenanChina CAS Engineering Laboratory for Nanozyme Key Laboratory of Biomacromolecules(CAS)CAS Center for Excellence in BiomacromoleculesInstitute of BiophysicsChinese Academy of SciencesBeijingChina Zhongyuan Nanozyme Laboratory ZhengzhouHenanChina

Head and neck squamous cell carcinoma (HNSCC) is a prevalent and lethal solid tumor with a high mortality rate. Conventional cancertreatments, including surgery, radiotherapy, and chemotherapy, primarily target cancer cell eradication. However, uncontrolled proliferation and metabolic activities of these cells result in abnormalities in nutrient levels, hypoxia, and immunosuppression within the tumor microenvironment (TME). These factors constrain the efficacy of traditional treatments by promoting drug resistance, recurrence, and metastasis. Nanomaterials (NMs), such as nanozymes, can exhibit enzymatic activity similar to that of natural enzymes and offer a promising avenuefor the direct modification of the TME through catalytic oxidation-reduction processes. Moreover, they can serve as sensitizers or drug deliverycarriers, enhancing the efficacy of traditional treatment methods. Recently, NMs have garnered significant attention from oncologists. Thisreview begins with an overview of the composition and unique characteristics of the TME. Subsequently, we comprehensively exploredthe application of NMs in the treatment of HNSCC. Finally, we discuss the potential prospects and challenges associated with usingNMs in biomedical research.

关键词： Nanomaterials Tumor microenvironment Antitumor therapy Tumor diagnosis Head and neck squamous cell carcinoma

Southwest Boundary of Yangtze and Cathaysia Blocks:Constraints from the Luojiashan Gabbro in Yingyangguan Region,Northeastern Guangxi

在线全文

学校读者我要写书评

暂无评论

Journal of Earth Science 2024年第5期35卷 1447-1463页

作者： Ya Qin Zuohai Feng Jiaming Zhu Yonggao Huang jie Wu Yun Zhou Yunfeng Xue Chunzeng Wang Collaborative Innovation Center for Exploration of Nonferrous Metal Deposits and Eficient Utilization of Resources by the Province and Ministry Guilin University of TechnologyGuilin 541004China Jiangsu Tuojia Engineering Design and Research Co. Ltd.Nanjing 211100China China Chemical Geology and Mine Bureau Henan Branch Zhengzhou 450000China University of Maine at Presque Isle Presque IsleMaine 04769USA

The Luojiashan gabbro is a newly discovered mafic pluton emplaced in the Neoproterozoic Yingyangguan Formation in Yingyangguan region of northeastern Guangxi,South *** whole-rock geochemical and zircon geochronological and Hf isotopic analyses are performed on the gabbro and comparisons are made with the coeval mafic-ultramafic sills and dikes located in Longsheng region of northern Guangxi in order to understand the magmatic origin,evolution,and tectonic setting of the Luojiashan gabbro and to address the location of the suture zone of the Southwestern Jiangnan Orogen(SJO).LA-ICP-MS zircon U-Pb ages obtained from the Luojiashan gabbro show that it was emplaced at~770 *** gabbro contains abundant inherited zircons aged at 0.9-1.3 Ga,consistent with age spectrum of the Cathaysia ***-normalized REE pattern,primitive mantle-normalized trace element spider diagram,incompatible element ratios of Nb/Ta,Zr/Hf,La/Nb,ba.Th,Th/La,and ba.La,and Th/Yb-Ta/Yb discrimination diagram of the gabbro are indicative of OIB-like geochemical characteristics and of derivation from partially melted garnet peridotite of the asthenospheric *** discrimination ba.ed on the trace and rare earth elements also indicate that the Luojiashan gabbro was emplaced in a within-plate extensional rift setting,proba.ly as a result of Rodinia supercontinent dismantling,lithospheric thinning,and underplating and upwelling of the asthenospheric *** on zircon age,Hf isotopic data and comparison between northern and northeastern Guangxi,it is suggested that the Yingyangguan region was tectonically situated in a different tectonic locale from the Longsheng region of northern Guangxi at about 770 Ma during the post-orogenic mafic-ultramafic magmatic event,with the former within the Cathaysia Block and the latter along the southeast margin of Yangtze *** suture between the Yangtze and Cathaysia blocks must be located between Yingyangguan of northeastern Gua

关键词： geochronology inherited zircon Luojiashan gabbro suture Yingyangguan tectonic

作业车间调度的多工序精确联动邻域结构混合进化算法

在线全文

学校读者我要写书评

暂无评论

计算机集成制造系统 2024年第2期30卷 537-552页

作者：巴智勇袁逸萍裴国庆王波新疆大学机械工程学院新疆乌鲁木齐830017 卓郎新疆智能机械有限公司新疆乌鲁木齐830057

针对作业车间调度问题,以最小化最大完工时间为优化目标,提出一种基于多工序精确联动邻域结构的混合进化算法。从理论上给出了关键块中工序无效移动的判定条件,据此设计了3对工序精确联动的邻域结构。为避免算法过早收敛,引入基于邻域... 详细信息

针对作业车间调度问题,以最小化最大完工时间为优化目标,提出一种基于多工序精确联动邻域结构的混合进化算法。从理论上给出了关键块中工序无效移动的判定条件,据此设计了3对工序精确联动的邻域结构。为避免算法过早收敛,引入基于邻域惩罚的交叉父本匹配选择算子与基于动态惩罚阈值的种群更新策略。通过与其他先进算法在车间调度问题基准算例上进行对比实验,验证了所提算法的有效性与稳定性。

关键词：作业车间调度精确多工序联动邻域结构混合进化算法多样化搜索

Evaluation of the Care of Children Aged 0 to 10 Years Hospitalized for Severe Malaria at the Tamba.ounda Health Center, Senegal

在线全文

学校读者我要写书评

暂无评论

Advances in Infectious Diseases 2024年第3期14卷 581-594页

作者： Tidiane Gadiaga Aminata Fall Alioune ba.ara Gueye Siré Sagna ba.al Cissé Mouhamadou Faly ba.Médoune Ndiop ba.acar Gueye Samba.Cor Sarr Sylla Thiam Elhadji ba.Konko Ciré Jean Louis Abdou Ndiaye Issa Wone Directorate of Research Planning and Statistics Ministry of Health and Social Action Dakar Senegal Faculty of Medicine Assane Seck University of Ziguinchor Ziguinchor Senegal Presidents Malaria Initiative USAID Dakar Senegal Tamba.ounda Health District Ministry of Health and Social Action Tambacounda Senegal Institute of Health and Development Faculty of Medicine Cheikh Anta Diop University Dakar Senegal National Malaria Control Program (NMCP) Dakar Senegal UFR Sant Faculty of Medicine Iba Der Thiam University of This This Senegal

Introduction: Malaria remains a public health priority in Senegal, particularly in Tamba.ounda, where it is one of the main causes of child mortality. The objective of this work was to evaluate the care of children under 10 years of age hospitalized at the Tamba.ounda Health Center and the factors associated with recovery. Methods: An analytical, retrospective, and descriptive cross-sectional study with exhaustive recruitment of children 0 to 120 months hospitalized at the Tamba.ounda reference health center for severe malaria (according to WHO criteria) between 1 January 2018 and 31 December 2021 was performed. Data collection was done through a questionnaire. Records, hospitalization records, and treatment records were the sources of collection. Data entry and analysis were performed on Epi Info 7.2 and R. Results: A total of 481 children hospitalized with severe malaria were recruited. The highest number of cases was recorded in 2018 (33.05%). In the four years of the study, peaks were always observed between October and November and the highest peak in November 2020 with 95 cases. The mean age was 65.64 months with a standard deviation of 29.28 months and a predominance of male (53.43%). The majority of people were admitted from the outpatient clinic (57.79%) and the rest (42.21%) on the recommendation of a peripheral health post. All hospitalized patients had a positive RDT and/or a positive thick drop. However, the sharp decline at admission or during hospitalization was positive in 93.80% of patients in our series, negative in 5.20% and not achieved in 1.00%. Seizures and severe anemia topped the list of signs of severity with 45.94% and 8.11%, respectively. In terms of evolution, for all hospitalized patients, there were 81.29% recovery, 10.19% referral to the Tamba.ounda regional hospital center for hospitalization, 4.99% death, 0.83% discharge and 2.70% unknown evolution. There was a statistically significant association between recovery without referral f

关键词： Severe Malaria Children Tamba.ounda Senegal

山地旅游安全事故致因研究——基于“三山五岳”的文本案例

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

干旱区资源与环境 2024年第3期38卷 201-208页

作者：黄佳杰巴兆祥复旦大学旅游学系上海200433

以国内外知名的“三山五岳”景区作为研究对象,搜集其相关的178个旅游安全事故典型案例,基于扎根理论对事故致因进行分析与讨论。结果表明:1)山地旅游安全事故的致因根据比重依次为:人为因素、环境因素、设备因素以及管理因素。2)致因... 详细信息

以国内外知名的“三山五岳”景区作为研究对象,搜集其相关的178个旅游安全事故典型案例,基于扎根理论对事故致因进行分析与讨论。结果表明:1)山地旅游安全事故的致因根据比重依次为:人为因素、环境因素、设备因素以及管理因素。2)致因分别对应8个子集:游客不安全行为、当地人不安全行为、天气不安全因素、陆地不安全因素、游客装备不齐全、设施设备不安全、管理水平低以及救援水平有限。3)借鉴旅游安全事故因果连锁理论,结合分析的要素与逻辑,建构了山地旅游安全分析模型。以政府、企业和游客三个维度为切入,为山地旅游业提出对策建议。

关键词：山地旅游旅游安全旅游事故扎根理论事故致因