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水堆安全壳内气体分布模拟计算

原子能科学技术 2002年第1期36卷 70-75页

作者：甘向阳 bottoni maurizio 周志伟清华大学核能技术设计研究院北京100084

本工作采用TH3SL程序对水堆事故后安全壳内的气体分布及蒸汽冷凝进行了随机模拟。校验计算表明

关键词：安全壳蒸汽冷凝空间分布随机模拟校验计算事故水堆气体分布 TH3SL程序

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延展表面凝结液膜的动量积分方法

原子能科学技术 2005年第4期39卷 296-302页

作者：博托尼舞理厨夫费拉拿大学物理系意大利帕拉帝索44100

采用动量积分方法分析压水堆发生失水事故时在安全壳的内表面上的液膜凝结、再浸润和蒸发过程。由凝结液膜的质量和动量守恒方程导出了凝结液膜在延展表面的子午线方向平均速度的积分微分方程。假设液膜以层流的方式流动,把导出的积分... 详细信息

采用动量积分方法分析压水堆发生失水事故时在安全壳的内表面上的液膜凝结、再浸润和蒸发过程。由凝结液膜的质量和动量守恒方程导出了凝结液膜在延展表面的子午线方向平均速度的积分微分方程。假设液膜以层流的方式流动,把导出的积分微分方程变成容易进行数值积分的液膜速度的一阶常微分方程,由此求得液膜厚度分布。液膜能量守恒方程的解给出了安全壳内壁面的温度分布。

关键词：凝结液膜动量积分失水事故

冷却剂丧失条件下钠冷快堆棒束传热的三维蒙特卡罗模拟方法

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原子能科学技术 2007年第2期41卷 203-210页

作者：博托尼舞理厨夫费拉拿大学物理所大气物理系意大利帕拉帝索44100

采用蒙特卡罗方法分析钠冷快堆在假想冷却剂丧失条件下燃料棒束的钠两相流传热。以分子运动理论的基本定律为基础,开发出替代宏观经验模型来分析反应堆棒束中的钠蒸发率和冷凝率的微观模型,且采用三维蒙特卡罗方法模拟分子的运动轨迹,... 详细信息

采用蒙特卡罗方法分析钠冷快堆在假想冷却剂丧失条件下燃料棒束的钠两相流传热。以分子运动理论的基本定律为基础,开发出替代宏观经验模型来分析反应堆棒束中的钠蒸发率和冷凝率的微观模型,且采用三维蒙特卡罗方法模拟分子的运动轨迹,分子间的碰撞率以及分子与棒束、分子与棒束组件盒壁的碰撞率。对包壳干涸区的再浸润现象用动力膜模型描述,并计算了通过液膜的液体速度分布和平均液膜速度,对于从冷凝液膜蒸发的钠分子则被重新记为蒙特卡罗计算的源项。用微观和宏观模型相结合的方法数字模拟了德国卡尔斯鲁厄核研究中心的堆外钠沸腾实验。

关键词：快堆安全分析蒙特卡罗方法钠蒸汽凝结液膜冷凝

A formal model for ledger management systems based on contracts and temporal logic

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Blockchain(Research and Applications) 2022年第1期3卷 65-79页

作者： Paolo bottoni Anna Labella Remo Pareschi Department of Computer Science Sapienza University of Rome00185RomaItaly Stake Lab University of Molise86100CampobassoItaly

A key component of blockchain technology is the ledger,viz.,a database that,unlike standard databases,keeps in memory the complete history of past transactions as in a notarial archive for the benefit of any future *** second-generation blockchains such as Ethereum,the ledger is coupled with smart contracts,which enable the automation of transactions associated with agreements between the parties of a financial or commercial *** coupling of smart contracts and ledgers provides the technological background for very innovative application areas,such as Decentralized Autonomous Organizations(DAOs),Initial Coin Offerings(ICOs),and Decentralized Finance(DeFi),which propelled blockchains beyond cryptocurrencies that were the only focus of first generation blockchains,such as ***,the currently used implementation of smart contracts as arbitrary programming constructs has made them susceptible to dangerous bugs that can be exploited maliciously and has moved their semantics away from that of legal *** propose here to recompose the split and recover the reliability of databases by formalizing a notion of contract modeled as a finite-state automaton with well-defined computational characteristics derived from encoding in terms of allocations of resources to actors,as an alternative to the approach based on *** complete the work,we use temporal logic as the basis for an abstract query language that is effectively suited to the historical nature of the information kept in the ledger.

关键词： Ledger Contract Database Transaction Automata theory Temporal logic

Blockchain-as-a-Service and Blockchain-as-a-Partner: Implementation options for supply chain optimization

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Blockchain(Research and Applications) 2023年第2期4卷 12-27页

作者： Paolo bottoni Claudio Di Ciccio Remo Pareschi Domenico Tortola Nicola Gessa Gilda Massa Department of Computer Science Sapienza University of RomeViale Regina Elena295Rome00161RMItaly Stake Lab University of MoliseC.da Fonte LapponePesche86090ISItaly Department of Bioscience and Territory University of MoliseC.da Fonte LapponePesche86090ISItaly TERIN-SEN-CROSS ENEA-Agenzia nazionale per le nuove tecnologiel'energia e lo sviluppo economico sostenibileVia Martiri di Monte Sole 4Bologna40129BOItaly e TERIN-SEN-CROSSENEA-Agenzia nazionale per le nuove tecnologiel'energia lo sviluppo economico sostenibile Piazzale Enrico Fermi 1Portici80055NAItaly

Smart contracts show a high potential to make supply chain management strategies epochally leap towards higher levels of productivity,not only in the functioning of production processes but also in terms of product innovation and overall economic *** article illustrates the principle of Income Sharing as a highly performing economic strategy for supply chains with a natural implementation in blockchain smart *** proposes a blockchain-based architecture that uses smart contracts to implement various algorithmic versions of the Income Sharing principle among companies participating in a supply *** formation of the total income and its consequent redistribution are calculated taking into account the role of the technological platform automating these procedures,which therefore becomes a party to the inter-company business project of a supply chain in the alternative roles,as feasible in business practice,of Blockchain-as-a-Service and *** approach is implemented on Hyperledger Fabric,the most widespread platform for private and consortium *** compare and justify this design choice with the alternative given by public blockchains,with specific attention to Ethereum.

关键词： Supply chain management Decentralized autonomous organization Income sharing Smart contract Distributed ledger Hyperledger fabric

Quality Problems in Waters Used for Drinking Purposes in Italy

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Biomedical and Environmental Sciences 1991年第4期4卷 339-347页

作者： E.FUNARI.A.BASTONE P.bottoni D.DEDONNO L.DONATI Department of Environmental Hygiene National Institute of HealthDepartment of Environmental Hygiene National Institute of HealthDepartment of Environmental Hygiene National Institute of HealthDepartment of Environmental Hygiene National Institute of Health

With a grant from the Italian Ministry of the Environment, the National Institute of Health (Istituto Superiore di Sanita) promoted and coordinated some activities aimed at determining the extent and the intensity of contamination of waters used for human consumption by some chemical agents, and describing causes and modalities of contamination and human health implications. The chemical agents examined were herbicides, nitrates, trihalomethanes, asbestos, manganese and fluoride. In this paper a first nationwide picture of these problems is reported.

关键词： Quality Problems in Waters Used for Drinking Purposes in Italy

Broadband diffuse optical spectroscopy of two-layered scattering media containing oxyhemoglobin,deoxyhemoglobin,water,and lipids

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Journal of Innovative Optical Health Sciences 2022年第3期15卷 92-106页

作者： Giles Blaney Martina bottoni Angelo Sassaroli Cristianne Fernandez Sergio Fantini Department of Biomedical Engineering Tufts University 4 Colby StMedfordMA 02155USA Department of Biomedical Engineering Politecnico di Torino 24 Corso Duca degli AbruzziTorinoTO 10129Italy

We investigated the relationship between chromophore concentrations in two-layered scattering media and the apparent chromophore concentrations measured with broadband optical spectroscopy in conjunction with commonly used homogeneous medium inverse *** used diffusion theory to generate optical data from a two-layered distribution of relevant tissue absorbers,namely,oxyhemoglobin,deoxyhemoglobin,water,and lipids,with a top-layer thickness in the range 1–15 *** generated data consisted of broadband continuous-wave(CW)diffuse reflectance in the wavelength range 650–1024 nm,and frequency-domain(FD)diffuse reflectance at 690 and 830 nm;two source-detector distances of 25 and 35mm were used to simulate a dual-slope *** data were inverted using diffusion theory for a semi-infinite homogeneous medium to generate reduced scattering coeffcients at 690 and 830nm(from FD data)and effective absorption spectra in the range 650–1024nm(from CW data).The absorption spectra were then converted into effective total concentration and oxygen saturation of hemoglobin,as well as water and lipid *** absolute values,it was found that the effective hemoglobin parameters are typically representative of the bottom layer,whereas water and lipid represent some average of the respective concentrations in the two *** concentration changes,lipid showed a significant cross-talk with other absorber concentrations,thus indicating that lipid dynamics obtained in these conditions may not be *** systematic simulations of broadband spectroscopy of two-layered media provide guidance on how to interpret effective optical properties measured with similar instrumental setups under the assumption of medium homogeneity.

关键词： Broadband spectroscopy two-layer medium heterogeneous forward model homo-geneous inverse model partial-volume effect

Unusual Case of Bilateral Breast Cancer: A Pure Encapsulated Papillary Breast Tumor of the Right Breast and a Contralateral Invasive Ductal Carcinoma

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Advances in Breast Cancer Research 2015年第2期4卷 39-43页

作者： Alberto Testori Valentina Errico Edoardo bottoni Emanuele Voulaz Stefano Meroni Roberto Travaglini Marco Alloisio General and Thoracic Surgery IRCCS Humanitas Research Hospital Via Manzoni Rozzano (Milan) Italy Breast Imaging Division European Institute of Oncology Via Ripamonti Milan Italy

Background: Intracystic papillary breast cancer is a very rare tumor that occurs most frequently in elderly postmenopausal women. Aim: In this article we presented a case of a 66-year-old woman who underwent excisional biopsy due to a right breast mass. Case presentation: Histological examination revealed the “pure” encapsulated papillary breast carcinoma without coexisting in situ neoplasm and/or invasive carcinoma. This is a rare lesion of the breast that can clinically mimic breast benign mass with only local or regionally aggressive course. Conclusion: In order to avoid misdiagnosis, both the clinician and the breast radiologist should have the possibility of diagnosing this tumor. Intracystic papillary carcinoma of the breast associated with lymph node?metastasis has rarely been reported, but the sentinel lymph node biopsy may be prudent in such cases, despite the non aggressive behavior.

关键词： Encapsulated Papillary Breast Carcinoma Intracystic Papillary Breast Carcinoma Lymph Node Breast Metastases

微小RNA-肿瘤蛋白p53反馈环路与慢性淋巴细胞白血病发病及结局的关联

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中华预防医学杂志 2011年第4期45卷 370-370页

作者： Fabbri M bottoni A Shimizu M 李海山不详中国检验检疫科学研究院化学品中心

染色体异常（13q、17p、11q缺失）与慢性淋巴细胞白咖病（CLL）的发生和再发有关，是一种常见的发病途径，但通过何种染色体异常影响CLL的发牛和结局的分子机制是未知的。

关键词：慢性淋巴细胞白血病蛋白p53 发病染色体异常环路反馈肿瘤分子机制