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Perioperative outcomes of transvaginal specimen extraction laparoscopic total gastrectomy and conventional laparoscopicassisted total gastrectomy

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World Journal of Gastrointestinal Surgery 2024年第6期16卷 1527-1536页

作者： Zhi-Cao Zhang Wen-Sheng Wang Jiang-Hong Chen Yuan-Hang Ma Qi-Fa Luo yun-bo Li Yang Yang Dan Ma Department of General Surgery Xinqiao Hospital of Army Medical UniversityChongqing 400037China

BACKGROUND Natural orifice specimen extraction surgery(NOSES)has emerged as a promising alternative compared to conventional laparoscopic-assisted total gastrectomy(LATG)for treating gastric cancer(GC).However,evidence regarding the efficacy and safety of NOSES for GC surgery is *** study aimed to compare the safety and feasibility,in addition to postoperative complications of NOSES and *** Dual circular staplers were used in Roux-en-Y digestive tract reconstruction for transvaginal specimen extraction LATG,and its outcomes were compared with LATG in a cohort of 51 GC patients with tumor size≤5 *** study was conducted from May 2018 to September 2020,and patients were categorized into the NOSES group(n=22)and LATG group(n=29).Perioperative parameters were compared and analyzed,including patient and tumor characteristics,postoperative outcomes,and anastomosis-related complications,postoperative hospital stay,the length of abdominal incision,difference in tumor type,postoperative complications,and postoperative *** Postoperative exhaust time,operation duration,mean postoperative hospital stay,length of abdominal incision,number of specific staplers used,and Brief Illness Perception Questionnaire score were significant in both groups(P<0.01).In the NOSES group,the postoperative time to first flatus,mean postoperative hospital stay,and length of abdominal incision were significantly shorter than those in the LATG *** in the NOSES group had faster postoperative recovery,and achieved abdominal minimally invasive incision that met aesthetic *** were no significant differences in gender,age,tumor type,postoperative complications,and postoperative survival between the two *** The application of dual circular staplers in Roux-en-Y digestive tract reconstruction combined with NOSES gastrectomy is safe and *** approach offers better short-term outcomes compared to LATG,while long-term survival

关键词： Gastric cancer Circular stapler Natural orifice specimen extraction surgery Laparoscopic-assisted total gastrectomy

Prognostic significance of oligodendrocyte transcription factor 2 expression in glioma patients:A systematic review and metaanalys

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World Journal of Clinical Cases 2024年第25期12卷 5739-5748页

作者： Peng-Cheng Li De-bo yun Ya-Xin Huang Qian-Yi Huang Department of Neurosurgery The Affiliated Nanchong Central Hospital of North Sichuan Medical CollegeNanchong 637000Sichuan ProvinceChina Department of Transfusion The Affiliated Nanchong Central Hospital of North Sichuan Medical CollegeNanchong 637000Sichuan ProvinceChina

BACKGROUND Gliomas are the most common primary central nervous system *** recent advances in the diagnosis and treatment of gliomas,patient prognosis remains ***,it is imperative to identify novel diagnostic biomarkers and therapeutic targets of glioma to effectively improve treatment *** To investigate the association between oligodendrocyte transcription factor 2(Olig2)expression and the outcomes of glioma *** The PubMed,Embase,Cochrane Library,and China National Knowledge Infrastructure databases were searched for studies(published up to October 2023)that investigated the relationship between Olig2 expression and prognosis of glioma *** quality of the studies was assessed using the Newcastle Ottawa *** analyses were performed using Stata Version 12.0 *** A total of 1205 glioma patients from six studies were included in the *** Olig2 expression was associated with better outcomes in glioma patients[hazard ratio(HR):0.81;95%(confidence interval)CI:0.51-1.27;P=0.000].Furthermore,the results of subgroup meta-analysis showed that high expression of Olig2 was associated with poor overall survival in European patients(HR:1.34;95%CI:0.79-2.27)and better prognosis in Asian patients(HR:0.43;95%CI:0.22-0.84).The sensitivity analysis showed that no single study had a significant effect on pooled HR,and there was also no indication of publication bias according to the Egger’s and Begger’s P value test or funnel plot *** High Olig2 expression may have a positive impact on the prognosis of glioma patients,and should be investigated further as a prognostic biomarker and therapeutic target for glioma.

关键词： Glioma Oligodendrocyte transcription factor 2 Prognosis Biomarker Meta-analysis

基于儿童需求的小学道德与法治教学的出发点与落脚点

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教学与管理 2024年第5期 41-43页

作者：张云波江苏省常州市武进区牛塘中心小学

基于儿童需求是道德与法治培育核心素养和培养必备品格的出发点和落脚点,是学生道德内化、思维发展和行为养成的需要。基于儿童需求的道德与法治课教学珍视童年生活的价值,尊重儿童的独特感悟,尊重儿童的权利,引领儿童正确的价值观,通... 详细信息

基于儿童需求是道德与法治培育核心素养和培养必备品格的出发点和落脚点,是学生道德内化、思维发展和行为养成的需要。基于儿童需求的道德与法治课教学珍视童年生活的价值,尊重儿童的独特感悟,尊重儿童的权利,引领儿童正确的价值观,通过有效性合作探究,针对性及时反思、真实性情境体验、两难性话题思辨等路径实现对儿童的引领。

关键词：小学道德与法治儿童需求

共同富裕视角下我国收入分配制度的完善与推进策略

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湘潭大学学报（哲学社会科学版） 2024年第4期48卷 81-88页

作者：周云波刘畅马丽南开大学政治经济学研究中心天津300071 南开大学经济学院天津300071 云南财经大学国际工商学院云南昆明650021

缩小收入差距、形成合理的收入分配格局是实现共同富裕的重要基础和内在要求。长期以来,伴随我国经济的快速增长,居民收入差距较大、收入分配不公平等问题也逐渐凸显,这种现象有悖于共同富裕的本质要求。因此有必要从当前收入分配领域... 详细信息

缩小收入差距、形成合理的收入分配格局是实现共同富裕的重要基础和内在要求。长期以来,伴随我国经济的快速增长,居民收入差距较大、收入分配不公平等问题也逐渐凸显,这种现象有悖于共同富裕的本质要求。因此有必要从当前收入分配领域存在的问题出发,以建设共同富裕为目标,探索优化收入分配格局的实践路径:在充分认识到我国收入分配过程与结果存在不公平的基础上,以“控制两端、培育中间”为原则,努力提升“两个占比”,逐步缩小居民收入差距并重点关注城乡居民收入差距,最终形成以中等收入群体为主导的“橄榄形”收入分配格局。同时,对深化收入分配领域改革提出政策建议,以此扎实推进全体人民的共同富裕进程。

关键词：收入差距收入分配共同富裕

一维接触排斥相互作用单自旋翻转费米气体的基态和淬火动力学性质

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物理学报 2024年第2期73卷 76-88页

作者：尹相国于海如郝亚江张云波山西大学理论物理研究所量子光学与光量子器件国家重点实验室极端光学协同创新中心太原030006 北京科技大学物理系理论物理研究所北京100083 浙江理工大学物理系浙江省光场调控重点实验室杭州310018

基于严格解方法,研究了一维排斥相互作用单自旋翻转费米气体的基态和淬火动力学性质.借助Bethe波函数,基态和不同本征态之间的单体关联函数和两体关联函数可以表示为简单函数之和,这一简洁形式可以极大地降低计算难度.系统初始状态为无... 详细信息

基于严格解方法,研究了一维排斥相互作用单自旋翻转费米气体的基态和淬火动力学性质.借助Bethe波函数,基态和不同本征态之间的单体关联函数和两体关联函数可以表示为简单函数之和,这一简洁形式可以极大地降低计算难度.系统初始状态为无相互作用的基态,当迅速把相互作用强度调节为有限大时,动量分布和关联函数出现周期性的振荡行为;当相互作用调节为比较弱时,振荡周期性好且振荡幅度小,系统可以用二能级模型近似;当相互作用调为非常强时,振荡周期性变差且振荡幅度大,但是依然存在主周期.此时整体偏离初态较远,但是在时间为mL^(2)/(2πh)时系统非常接近初态.

关键词：一维费米气体动量分布关联函数淬火动力学

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贫困脆弱性对农村居民主观幸福感的影响--基于CFPS数据的实证分析

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西北人口 2024年第1期45卷 98-112页

作者：黄杏子周云波南开大学经济学院天津300071

实现共同富裕的落脚点在于提高人民群众的幸福感,其中最艰巨最繁重的任务在农村。现阶段我国农村居民的整体幸福感水平仍还有较大的增进空间,与此同时,农村居民也面临着较高的在未来陷入相对贫困的风险,其面临的这种风险是否是制约幸福... 详细信息

实现共同富裕的落脚点在于提高人民群众的幸福感,其中最艰巨最繁重的任务在农村。现阶段我国农村居民的整体幸福感水平仍还有较大的增进空间,与此同时,农村居民也面临着较高的在未来陷入相对贫困的风险,其面临的这种风险是否是制约幸福感进一步提升的因素?对这一问题的研究对探索增进我国农村居民幸福感的路径具有必要性。文章基于北京大学中国家庭追踪调查(CFPS)2014年和2018年面板数据,对我国农村居民的贫困脆弱性与其主观幸福感之间的关系进行了实证分析,并具体探讨了其中的作用路径与作用机制。研究发现:(1)以收入相对贫困标准测度得到的农村居民贫困脆弱性仍较高,且其与个体的主观幸福感之间存在显著的负向关系,即个体的贫困脆弱性程度越高,其主观幸福感水平越低。这一结论在进行一系列稳健性检验后依旧成立。(2)异质性分析发现,处在中西部地区的居民以及男性居民贫困脆弱性的主观幸福感降低效应更为严重。(3)作用路径分析发现,贫困脆弱性的幸福感降低效应主要是由风险脆弱性,即个体应对风险能力的欠缺所导致的。作用机制分析发现,农村居民主观社会地位的提高、社会信任程度的增加以及对未来信心的增强均能够有效缓解贫困脆弱性对个体主观幸福感的负面影响。

关键词：贫困脆弱性相对贫困主观幸福感农村居民

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区块链技术在知识产权领域的研究与应用

产业科技创新 2024年第3期6卷 33-36页

作者：贠博西安财经大学陕西西安710100

区块链是一种通过P2P连接的节点协议认证的,交易资料以块的形式存储的技术,区块相互连接形成链,分散存储在每个节点上的分类账或数据库中。这种技术涵盖了作品创作等众多知识产权领域,为知识产权所有者提供了不可否认的证据,便利了智能... 详细信息

区块链是一种通过P2P连接的节点协议认证的,交易资料以块的形式存储的技术,区块相互连接形成链,分散存储在每个节点上的分类账或数据库中。这种技术涵盖了作品创作等众多知识产权领域,为知识产权所有者提供了不可否认的证据,便利了智能合同和资产支持代币(ABT)在知识产权交易中的运用。在探讨区块链技术对知识产权的影响时,也必须认识到其使用过程中存在的局限性。本文旨在分析区块链技术的特性,并深入讨论其在知识产权智能管理方面的优点和局限性。通过这些讨论和分析,间接提出了国内在广泛应用区块链技术于知识产权领域的条件因素。

关键词：区块链知识产权加密货币局限性

Bufei Huoxue capsule (补肺活血胶囊) alleviates silicosis by inhibiting the activation of nucleotide-like receptor containing pyrin domain 3 inflammasome and macrophages polarization based on network pharmacology

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Journal of Traditional Chinese Medicine 2024年

作者： HANG Wenlu WANG Lin bo yun ZUO Shurun WANG Songquan LI Haiquan BU Chunlu ZHAO Jie ZHOU Xianmei Department of Respiratory and Critical Care Medicine， Second Affiliated Hospital of Xuzhou Medical University Medical College of Anhui University of Science and Technology School of Mechatronic Engineering， Jiangsu Normal University Department of Respiratory Medicine， Jiangsu Province Hospital of Chinese Medicine

OBJECTIVE: To predict the targets of Bufei Huoxue capsule （补肺活血胶囊， BFHX） using network pharmacology analysis and to explore its effects and functional targets in a silicotic rat ***: The drug and disease targets were correlated through network pharmacology analysis to explore the targets and signaling pathways of BFHX affecting silicosis. NR8383 cells were cultured to verify the core genes and pathways. A rat model of silicosis was established to verify whether the mechanism behind SiO2-caused pulmonary fibrosis was alleviated by BFHX （0.82 g/kg） and how it affected key targets and pathways. RESULTS: Overlapping BFHX and silicotic gene targets produced 159 interactive targets， and 55 were screened by network topology analysis. The results of gene ontology and Kyoto encyclopedia of genes and genomes enrichment analyses suggested that BFHX could affect silicosis through the nucleotide-like receptor containing pyrin domain 3 （NLRP3） inflammasome. In NR8383 cells， the expression of core genes related to the NLRP3 inflammasome could be inhibited by BFHX treatment. BFHX reduced the degree of alveolitis and collagen deposition， attenuating pulmonary fibrosis in SiO2-induced rat model. Pulmonary macrophage pyroptosis after SiO2exposure was observed under transmission electron microscopy. BFHX alleviated the morphological characteristics of pyroptosis. BFHX also reduced the expression of NLRP3， caspase-1， interleukin-1 beta （IL-1β）， IL-18， IL-6， and tumor necrosis factor-alpha in lung tissues of silicotic rat model. BFHX affected the K ion content in bronchoalveolar lavage fluid when assessed by energy dispersive spectrometer testing. The expression of CD68+and CD206+were also reduced after BFHX intervention. CONCLUSION: NOD-like receptor signaling is vital for BFHX’s effects on silicosis. It exerts anti-pulmonary fibrosis effects by inhibiting pulmonary macrophage pyroptosis and polarization through NLRP3 inflammasome activation.

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电动伸缩臂履带起重机的抗倾覆稳定性研究

建筑机械 2024年第9期 220-222页

作者：李允博辽宁抚挖重工机械股份有限公司辽宁抚顺113126

文章通过对电动伸缩臂履带起重机的抗倾覆稳定性进行分析,得出试验前抗倾覆稳定性的校核计算方法,总结出整机抗倾覆稳定性试验方法,并在实际生产中将校核计算结果和试验方法进行验证。

关键词：电动履带起重机抗倾覆稳定性载荷试验方法

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