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Prevalence and risk factors of stroke in China:a national serial cross-sectional study from 2003 to 2018

Stroke & Vascular Neurology 2023年第3期8卷 238-248,I0086-I0095页

作者： Dai-Shi Tian Chen-Chen Liu Chao-Long Wang Chuan Qin Ming-Huan Wang Wen-Hua Liu jian Liu Han-Wen Zhang Rong-Guo Zhang Shao-Kang Wang Xiao-Xiang Zhang Liang Wang Deng-Ji Pan jian-ping Hu Xiang Luo Sha-Bei Xu Wei Wang Department of Neurology Tongji Hospital of Tongji Medical College of Huazhong University of Science and TechnologyWuhanHubeiChina Department of Epidemiology and Biostatistics Tongji Medical College of Huazhong University of Science and TechnologyWuhanHubeiChina Department of Scientific Research Management Tongji Hospital of Tongji Medical College of Huazhong University of Science and TechnologyWuhanHubeiChina Infervision Medical Technology Co. LtdBeijingChina Department of Computer Center Tongji Hospital of Tongji Medical College of Huazhong University of Science and TechnologyWuhanHubeiChina Centre for Health Statistics Information National Health Commission of the People's Republic of ChinaBeijingChina

Stroke imposes a substantial burden *** the rapid economic and lifestyle transition in China,trends of the prevalence of stroke across different geographic regions in China remain largely *** on the data in the National Health Services Surveys(NHSS),we assessed the prevalence and risk factors of stroke in China from 2003 to *** this study,data from 2003,2008,2013,and 2018 NHSS were *** cases were based on participants’self-report of a previous diagnosis by *** estimated the trends of stroke prevalence for the overall population and subgroups by age,sex,and socioeconomic factors,then compared across different geographic *** applied multivariable logistic regression to assess associations between stroke and risk *** number of participants aged 15 years or older were 154,077,146,231,230,067,and 212,318 in 2003,2008,2013,and 2018,respectively,among whom,1435,1996,3781,and 6069 were stroke *** age and sex standardized prevalence per 100,000 individuals was 879 in 2003,1100 in 2008,1098 in 2013,and 1613 in *** per 100,000 individuals in rural areas increased from 669 in 2003 to 1898 in 2018,while urban areas had a stable trend from 1261 in 2003 to 1365 in *** geographic regions,the central region consistently had the highest prevalence,but the western region has an alarmingly increasing trend from 623/100,000 in 2003 to 1898/100,000 in 2018(Ptrend<0.001),surpassing the eastern region in *** age,male sex,rural area,central region,hypertension,diabetes,depression,low education and income level,retirement or unemployment,excessive physical activity,and unimproved sanitation facilities were significantly associated with *** conclusion,the increasing prevalence of stroke in China was primarily driven by economically underdeveloped *** is important to develop targeted prevention programs in underdeveloped *** traditional risk factors,more attenti

关键词： prevention sectional income

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解析求解非线性相对运动的最优重构问题

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宇航学报 2013年第7期34卷 909-916页

作者：曹静袁建平罗建军西北工业大学航天飞行动力学技术重点实验室西安710072

椭圆轨道相对运动模型的线性化导致其在大尺度相对运动应用中精度不能满足需求。针对任意椭圆轨道上的大尺度航天器编队最优重构问题,提出一种基于椭圆轨道非线性相对运动模型的近似解析求解方法。首先通过变分法建立了非线性最优重构... 详细信息

椭圆轨道相对运动模型的线性化导致其在大尺度相对运动应用中精度不能满足需求。针对任意椭圆轨道上的大尺度航天器编队最优重构问题,提出一种基于椭圆轨道非线性相对运动模型的近似解析求解方法。首先通过变分法建立了非线性最优重构问题的数学模型;然后采用摄动法,以偏近点角为积分变量求得了不含特殊积分的解析开环最优控制,有效地避免了真近点角域下最优控制解所含有的特殊积分。仿真验证了所求最优控制的有效性和优越性,结果表明在相对运动尺度较大时,相比基于椭圆轨道线性化模型的最优控制,在燃耗保持相近的情况下,所求非线性控制有效地降低了重构误差。

关键词：航天器编队飞行椭圆轨道最优重构非线性相对运动模型摄动法近似解析解

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Anti-Helicobacter pylori therapy followed by celecoxib on progression of gastric precancerous lesions

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World Journal of Gastroenterology 2009年第22期15卷 2731-2738页

作者： Li-Jing Zhang Shi-Yan Wang Xiao-Hui Huo Zhen-Long Zhu jian-Kun Chu Jin-Cheng Ma Dong-Sheng Cui ping Gu Zeng-Ren Zhao Ming-Wei Wang Jun Yu Department of Gastroenterology the First Affiliated Hospital of Hebei Medical University Shijiazhuang 050051 Hebei Province China Department of Medicine and Therapeutics the Prince of Wales Hospital the Chinese University of Hong Kong Hong Kong China Department of Pathology the First Affiliated Hospital of Hebei Medical University Shijiazhuang 050051 Hebei Province China Department of Neurology the First Affiliated Hospital of Hebei Medical University Shijiazhuang 050051 Hebei Province China Department of Surgery the First Affiliated Hospital of Hebei Medical University Shijiazhuang 050051 Hebei Province China

AIM： To evaluate whether celecoxib, a selective cyclooxygenase 2 （COX-2） inhibitor, could reduce the severity of gastric precancerous lesions following Hel/cobacter pylori （H pylorl） eradication. METHODS： H pylori-eradicated patients with gastric precancerous lesions randomly received either celecoxib （n = 30） or placebo （n = 30） for up to 3 mo. COX-2 expression and activity was determined by immunostaining and prostaglandin E2 （PGE2） assay, cell proliferation by Ki-67 immunostaining, apoptosis by TUNEL staining and angiogenesis by microvascular density （MVD） assay using CD31 ***： COX-2 protein expression was significantly increased in gastric precancerous lesions （atrophy, intestinal metaplasia and dysplasia, respectively） compared with chronic gastritis, and was concomitant with an increase in cell proliferation and angiogenesis. A significant improvement in precancerous lesions was observed in patients who received celecoxib compared with those who received placebo （P 〈 0.001）. Of these three changes, 84.6% of sites with dysplasia regressed in patients treated with celecoxib （P = 0.002） compared with 60% in the placebo group, suggesting that celecoxib was effective on the regression of dysplasia. COX-2 protein expression （P 〈 0.001） and COX-2 activity （P 〈 0.001） in the gastric tissues were consistently lower in celecoxib-treated patients compared with the placebo-treated subjects. Moreover, it was also shown that celecoxib suppressed cell proliferation （P 〈 0.01）, induced cell apoptosis （P 〈 0.01） and inhibited angiogenesis with decreased MVD （P 〈 0.001）. However, all of these effects were not seen in placebo-treated subjects. Furthermore, COX-2 inhibition resulted in the up-regulation of PPARy expression, a protective molecule with anti-neoplastic effects. CONCLUSION： H pylori eradication therapy followed by celecoxib treatment improves gastric precancerous lesions by inhibiting COX-2 activity, inducing apoptosis, and suppressing cell proliferation

关键词： Apoptosis Cyclooxygenase 2 Gastric precancerous lesions Helicobacter pylori Microvessel density Proliferation

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基于子带谱平滑度的音频篡改检测

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应用科学学报 2010年第2期28卷 142-146页

作者：丁琦平西建解放军信息工程大学信息工程学院郑州450002 解放军信息工程大学电子技术学院郑州450004

针对音频篡改过程中重采样操作的检测,通过对插值音频信号频谱特性的分析,提出一种频谱测度即子带谱平滑度,用以度量音频信号在各子带频谱的波动程度,并提出用子带谱平滑度作音频信号篡改检测的方法及其具体实现步骤.实验结果表明,该方... 详细信息

针对音频篡改过程中重采样操作的检测,通过对插值音频信号频谱特性的分析,提出一种频谱测度即子带谱平滑度,用以度量音频信号在各子带频谱的波动程度,并提出用子带谱平滑度作音频信号篡改检测的方法及其具体实现步骤.实验结果表明,该方法不仅能够准确地检测出音频信号是否经过插值和拼接处理,还能比较准确地估算出信号插值前的原始采样率,为音频取证提供更多有用信息.

关键词：音频篡改检测插值拼接子带谱平滑度

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Symmetrical femtosecond laser arc incision in correcting corneal astigmatism in cataract patients

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International Journal of Ophthalmology(English edition) 2023年第12期16卷 1996-2003页

作者： Zun-Xia Hu Jing Sima Jia-Guo Cao Yan Ke Ying-Ying Zhang Qiong-Tian Guo Yu-ping He Hong-Xia Liao Xiao Tan bo Qin Li Li Femtosecond laser-assisted astigmatic keratotomy 1Aier Eye Hospital Jinan UniversityShenzhen 518032Guangdong ProvinceChina Nanning Aier Eye Hospital Nanning 530012Guangxi Zhuang Autonomous RegionChina

AIM:To evaluate the effect of symmetrical arc incision correcting corneal astigmatism in femtosecond laserassisted phacoemulsification(FLACS).METHODS:This study enrolled patients with cataract combined with regular corneal astigmatism of>0.75 D,who underwent *** arc incision was set at 8 mm diameter and 85%*** follow-up time was 3-24mo(4.92±3.49mo).Pentacam recorded the corneal astigmatism and higher-order aberration at pre-operation and *** changes in corneal astigmatism were analyzed by Alpins *** correlation of astigmatism type,age,corneal horizontal diameter,corneal thickness,arc incision length,and correction index(CI)was analyzed,and the residual corneal astigmatism was compared with the residual whole eye ***:Totally 79 patients(102 eyes)were enrolled,10 patients had corneal epithelial injury,1 patient occurred corneal epithelial *** corneal astigmatism was 1.23±0.38 D pre-operation,and decreased to 0.76±0.39 D post-operation(t=10.146,P=0.000).Corneal high-order aberration was 0.17±0.08μm pre-operation and 0.24±0.11μm post-operation(t=-5.186,P=0.000).The residual corneal astigmatism and residual whole eye astigmatism were no significant difference(t=-0.347,P=0.729).Using Alpin’s method,the following were determined:target-induced astigmatism(TIA)=1.23±0.38 D,surgeryinduced astigmatism(SIA)=0.77±0.45 D,difference vector(DV)=0.77±0.39 D,and CI=0.54±***,astigmatism size,corneal horizontal diameter,corneal thickness,and arc incision length were not correlated with *** CI for against the rule astigmatism(ATR)was better than that for with the rule astigmatism(WTR;P=0.001).CONCLUSION:Femtosecond laser-assisted astigmatic keratotomy has better CI of ATR,but increase higher-order corneal *** is not ideal,it’s not a perfect choice if we pursue ideal correction effect.

关键词： femtosecond laser arc incision keratotomy astigmatism cataract higher-order aberrations

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光纤化学传感技术研究近况

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光谱学与光谱分析 2014年第8期34卷 2035-2039页

作者：汪舰魏建平杨波高志扬张利伟杨学峰河南理工大学物理化学学院河南焦作454000 中国科学院西安光学精密机械研究所瞬态光学与光子技术国家重点实验室陕西西安710119 河南理工大学瓦斯地质与瓦斯治理重点实验室河南焦作454000 河南理工大学安全学院河南焦作454000

光纤化学传感器作为传感器的一个重要分支,结合了化学和光学的相关技术,将化学制膜、光纤技术以及化学分析中的分光光度法、拉曼光谱、荧光光谱、折射率检测等方法相融合,以其微型化,抗电磁干扰,传输信息量大,拥有自身参比等特点不断向... 详细信息

光纤化学传感器作为传感器的一个重要分支,结合了化学和光学的相关技术,将化学制膜、光纤技术以及化学分析中的分光光度法、拉曼光谱、荧光光谱、折射率检测等方法相融合,以其微型化,抗电磁干扰,传输信息量大,拥有自身参比等特点不断向前发展。简要综述了光纤化学传感技术研究近况和未来的发展趋势。重点对光纤pH化学传感器、光纤离子化学传感器和光纤气体化学传感器进行了介绍。简要分析了常见的敏感膜制备方法如化学键合法和溶胶凝胶(sol-gel)等方法。新型光纤——微结构光纤的出现为光纤化学传感器开辟了新的发展方向。由于其具有大的内表面积,结构设计灵活多样,光纤内部提供感应场所等特点,快速度成为光纤化学传感器的重要发展方向和研究热点。对微结构光纤衍生而来的新型光纤化学传感器进行了详细评述,最后对光纤化学传感器的未来进行展望。

关键词：光纤化学传感化学传感微结构光纤

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基于用户分配和负载的频谱分配算法

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软件学报 2013年第7期24卷 1638-1649页

作者：陈剑吴建平李贺武解放军理工大学指挥自动化学院江苏南京210007 清华大学计算机科学与技术系北京100084 清华大学信息网络工程研究中心北京100084

提出了一种基于用户分配和负载的频谱分配算法.该算法包括两部分:用户分配子算法和频谱分配子算法.用户分配子算法首先基于聚类划分理论,使分配到相同访问点下的用户具有相近的信噪比,缓解了无线接入网络中普遍存在的远近效应问题.在该... 详细信息

提出了一种基于用户分配和负载的频谱分配算法.该算法包括两部分:用户分配子算法和频谱分配子算法.用户分配子算法首先基于聚类划分理论,使分配到相同访问点下的用户具有相近的信噪比,缓解了无线接入网络中普遍存在的远近效应问题.在该用户分配基础上,频谱分配子算法根据各访问点的负载及其关联用户信噪比的平均值计算最优频谱分配.该算法具有可实现性、多项式时间的计算复杂度以及比例公平性.真实数据驱动的仿真实验结果表明,该算法能够有效地提高系统吞吐量,同时大幅度减小访问点的报文缓冲区队长.

关键词：用户分配关联控制频谱分配动态频谱访问负载

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Interface repairing for AA5083/T2 copper explosive composite plate by friction stir processing

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Transactions of Nonferrous Metals Society of China 2021年第9期31卷 2585-2596页

作者： jian WANG Xiao-wei WANG bo LI Cheng CHEN Xiao-feng LU School of Mechanical and Power Engineering Nanjing Tech UniversityNanjing 211816China Sunpower Technology(jiangsu)Co. Ltd.Nanjing 211112China Additive Manufacturing and Intelligent Equipment Research Institute School of Mechanical and Power EngineeringEast China University of Science and TechnologyShanghai 200237China

Multi-pass friction stir processing(M-FSP)was performed to repair the interface defects of AA5083/T2 copper explosive composite *** interface morphology and its bonding mechanism were *** results show that higher rotation speed and lower transverse speed produce more heat generated during *** defect-free and good mechanical properties of the AA5083/T2 copper composite plate can be obtained under the condition of the rotation speed of 1200 r/min,the transverse speed of 30 mm/min and the overlap of 2/***,M-FSP changes the interface bonding mechanism from metallurgical bonding to vortex connection,improving the bonding strength of composite plate,which can guarantee the repairing quality of composite plates.

关键词： friction stir processing aluminum/copper composite plate interface repairing mechanical properties

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Comparison of persistent submacular fluid in different preoperative macular status after vitrectomy for rhegmatogenous retinal detachment

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International Journal of Ophthalmology(English edition) 2018年第11期11卷 1796-1801页

作者： jian-bo Mao Jing-Jing Lin Xue-Ting Yu Dan Cheng Yi-Qi Chen Ji-Wei Tao Han-Fei Wu Lu jiang Yun Zhang Li-Jun Shen The Affiliated Eye Hospital Wenzhou Medical University

AIM： To compare the incidence of persistent submacular fluid（SMF） and visual outcome after pars plana vitrectomy（PPV） for rhegmatogenous retinal detachment（RRD） in different preoperative macular status according to optical coherence tomography（OCT）.METHODS： A non-randomized, retrospective review was performed for patients who underwent successful PPV for RRD. OCT exams were taken preoperatively and 1 mo after surgery, until SMF disappeared. According to the preoperative macular status on OCT, patients were divided into two groups： macula-off RRD（Group A） and maculaon RRD（Group B）. In Group A, there were two subgroups： macula partly detached（Group A1） and macula totally detached（Group A2）. The main outcome measures were the presence of SMF on OCT 1 mo after surgery, and the preoperative and postoperative best corrected visual acuities（BCVA）, among the different groups and depending on the presence or absence of persistent ***： A total of 139 eyes of 139 patients were included in the study. Persistent SMF at 1 mo after surgery was 15.8%（22/139）, all occurring in Group A（22/101）; Group B had no SMF at 1 mo after surgery（0/38, P=0.002）. The incidence of persistent SMF at 1 mo after surgery in Group A1 was 50%（14/28）, and in Group A2 was 11.0%（8/73, P〈0.001）. Significant differences were shown between the presence and absence of persistent SMF on foveolaoff RRD, the preoperative BCVA, the 1 mo postoperative BCVA, and the degree of the BCVA improvement from 1 mo postoperatively to the final follow-up（P〈0.05）. However, there were no significant differences in the final BCVA（P〉0.05）.CONCLUSION： Persistent SMF after PPV for retinal detachment is associated with preoperative macular status. Macula-uninvolving RRD shows no persistent SMF after PPV. Macular partly detached RRD has a higher incidence of SMF than macula totally detached RRD after PPV. The persistence of SMF may be responsible for the delayed visual recovery, whereas there were no significant differences i

关键词： submacular fluid rhegmatogenous retinal detachment optical coherence tomography vitrectomy macula

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Regional gray matter abnormality in hepatic myelopathy patients after transjugular intrahepatic portosystemic shunt: a voxel-based morphometry study

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Neural Regeneration Research 2019年第5期14卷 850-857页

作者： Kang Liu Gang Chen Shu-Yao Ren Yuan-Qiang Zhu Tian-Lei Yu ping Tian Chen Li Yi-Bin Xi Zheng-Yu Wang jian-Jun Ye Guo-Hong Han Hong Yin Department of Radiology Xijing Hospital Air Force Military Medical University (Fourth Military Medical University) Department of Radiology Lanzhou General Hospital Lanzhou Military Command Xijing Hospital of Digestive Diseases Air Force Military Medical University (Fourth Military Medical University) Life Sciences Research Center School of Life Sciences and Technology Xidian University

Hepatic myelopathy is a complication seen in patients with chronic liver failure with physiologic or iatrogenic portosystemic shunting. The main symptom is progressive lower limb dyskinesia. The role of the brain motor control center in hepatic myelopathy is unknown. This study aimed to investigate the gray matter changes in patients with hepatic myelopathy secondary to transjugular intrahepatic portosystemic shunt and to examine their clinical relevance. This was a cross-sectional study. Twenty-three liver failure patients with hepatic myelopathy(hepatic myelopathy group), 23 liver failure patients without hepatic myelopathy(non-hepatic myelopathy group) after transjugular intrahepatic portosystemic shunt, and 23 demographically matched healthy volunteers were enrolled from March 2014 to November 2016 at Xijing Hospital, Air Force Military Medical University(Fourth Military Medical University), China. High-resolution magnetization-prepared rapid gradient-echo brain imaging was acquired. Group differences in regional gray matter were assessed using voxel-based morphometry analysis. The relationship between aberrant gray matter and motor characteristics was investigated. Results demonstrated that compared with the non-hepatic myelopathy group, gray matter volume abnormalities were asymmetric, with decreased volume in the left insula(P = 0.003), left thalamus(P = 0.029), left superior frontal gyrus(P = 0.006), and right middle cingulate cortex(P = 0.021), and increased volume in the right caudate nucleus(P = 0.017), corrected with open-source software. The volume of the right caudate nucleus in the hepatic myelopathy group negatively correlated with the lower limb clinical rating of the Fugl-Meyer Assessment(r = –0.53, P = 0.01). Compared with healthy controls, patients with and without hepatic myelopathy exhibited overall increased gray matter volume in both thalami, and decreased gray matter volume in both putamen, as well as in the globus pallidus, cerebellum, and

关键词： portosystemic shunt hepatic myelopathy hepatic encephalopathy magnetic resonance imaging gray matter lower limb Fugl-Meyer Assessment basal ganglia caudate nucleus voxel-based morphometry

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