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Improving beef hamburger quality and fatty acid profiles through dietary manipulation and exploitation of fat depot heterogeneity

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Journal of Animal Science and Biotechnology 2015年第1期6卷 111-121页

作者： cletos Mapiye Jennifer L Aalhus Payam Vahmani David c Rolland Timothy A McAllister Hushton c block Bethany Uttaro Spencer D Proctor Michael E R Dugan Agriculture and Agri-Food canada Lacombe Research Centre6000 C and E TrailLacombeAlberta T4L 1 W1Canada Department of Animal Sciences Faculty of AgriSciencesStellenbosch UniversityP.Bag X1Matieland 7602 South Africa Agriculture and Agri-Food canada Lethbridge Research Centre1st Avenue South 5403PO Box 3000LethbridgeAlberta T1J 4B1 Canada Metabolic and cardiovascular Diseases Laboratory Diabetes and Mazankowski InstitutesLi Ka Shing Centre for Health Research Innovation University of AlbertaEdmontonAlberta T6G 2E1Canada

Background： Hamburger is the most consumed beef product in North America, but lacks in nutritional appeal due to its high fat content and high proportion of saturated fatty acids （SFA）. Objectives of the present study were to improve the FA profiles of hamburgers made with perirenal fat （PRF） and subcutaneous fat （ScF） when feeding steers different diets along with examining differences in sensory attributes and oxidative stability. Diets included a control diet containing 70：30 red clover silage： barley based concentrate, a diet containing sunflower-seed （SS） substituted for barley, and diets containing SS with 15% wheat dried distillers＇ grain with solubles （DDGS-15） or 30% DDGS （DDGS-30）. Hamburgers were made from triceps brachii and either PRF or ScF （80：20 w/w）. Results： Perirenal fat versus ScF hamburgers FA had 14.3% more （P 〈0.05） 18：0, 11.8% less cis （c）9-18：1 （P 〈0.05）, and 1.82% more total trdns （t）-18：1 mainly in the form of tl 1-18：1. During sensory evaluation, PRF versus ScF hamburgers had greater （P 〈0.05） mouth coating, but the difference was less than one panel unit. Examining effects of steer diet within PRF hamburgers, feeding the SS compared to the control diet increased （P 〈0.05） t-18：1 by 2.89% mainly in the form of tl 1-18：1, feeding DGGS-15 diet led to no further changes （P 〉0.05）, but feeding DDGS-30 diet reduced the proportions of （P 〈0.05） of t-18：1 chiefly tl 1-18：1. Feeding SS and DDGS diets had small but significant （P 〈0.05） effects on hamburger sensory attributes and oxidative stability. conclusions： Feeding high-forage diets including SS and 15% DDGS, and taking advantage of the FA heterogeneity between fat depots offers an opportunity to differentially enhance beef hamburgers with 18：2n-6 biohydrogenation products （Le., t11-18：1） with potential human health benefits without compromising their sensory attributes and oxidative stability during retail display.

关键词： Beef DDGS Fat depot Fatty acids Sensory attributes Oxidative stability

Will Transcatheter Aortic Valve Replacement(TAVR)be the Primary Therapy for Aortic Stenosis?

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cardiovascular Innovations and Applications 2016年第B5期1卷 273-284页

作者： Jose F.condado Peter c.block Structural Heart and Valve center Division of CardiologyEmory University School of MedicineAtlantaGAUSA

Transcatheter aortic valve replacement(TAVR)is increasingly used for the treatment of high or very high surgical risk patients with severe aortic stenosis(AS)or failing surgical bioprosthesis(valve-in-valve,VIV-TAVR).In TAVR,the collapsed transcatheter heart valve(THV)is introduced using the delivery system inserted from the femoral artery(preferred)or other alternative accesses(transapical,transaortic,transcarotid,subclavian/transinnominate or transcaval).The delivery system is then advanced until coaxially aligned with the aortic annulus,where the THV is *** procedure can be associated with complications such as access site injury(vascular complication),paravalvar leak,cerebrovascular events and conduction ***,the rapid acceptance and successes observed with TAVR have been made possible through careful patient selection,preprocedural planning(*** annular sizing),THV technology(*** generation valves),and procedural techniques(*** TF-TAVR and alternative percutaneous access options),as well as a decrease in complications as TAVR experience *** the results or ongoing clinical trials evaluating TAVR in intermediate surgical risk patients are pending,it is likely that TAVR will soon be approved for lower risk patients as well.

关键词： aortic stenosis transcatheter aortic valve replacement valve-in-valve

婴儿色素性神经外胚层瘤——一个罕见的恶性病例

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国际口腔医学杂志 1982年第2期 98-101页

作者： James c block ,高水仙

目前称之为婴儿色素性或黑色素性的神经外胚层瘤,一般发生于不到一岁幼儿的上颌骨。成人偶尔也有患者,但非常罕见。虽然有些黑色素性神经外胚层瘤具有生长很快和不良的临床与X线表现,但其生物学行为却是良性过程。这是一个自相矛盾的现象,

关键词：神经外胚层瘤香草基黑色素细胞神经母细胞瘤成神经细胞瘤神经组织肿瘤苯乙醇酸扁桃酸苯乙酸肿瘤复发切除手术恶性黑色素瘤色素性肿瘤上领骨

The effects of EPA + DHA and aspirin on inflammatory cytokines and angiogenesis factors

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World Journal of cardiovascular Diseases 2012年第1期2卷 14-19页

作者： Robert c. block Usawadee Dier Pedro calderon Artero Gregory c. Shearer Lisa Kakinami Mark K. Larson William S. Harris Steve Georas Shaker A. Mousa Department of community and Preventive Medicine the University of Rochester School of Medicine and Dentistry Rochester New York.

Objective: In a recent study, we showed that the combination of aspirin plus the ω3 fatty acids eicosapen-taenoic acid (EPA) and docosahexaenoic acid (DHA) synergistically inhibited platelet function. As aspirin, EPA, and DHA have demonstrated anti-inflammatory properties, we hypothesized that the ingestion of EPA and DHA, with and without aspirin, would reduce plasma levels of inflammatory cytokines and angiogenesis factors more than aspirin alone and before aspirin was ingested. Methods: Using multiplex technology, we investigated the effects of aspirin (single-dose 650 mg on day 1), EPA + DHA (3.4 g/d for days 2 - 29), and aspirin with EPA + DHA (day 30) on plasma levels of inflammatory cytokines and angiogenesis factors in healthy adults. Results: Aspirin alone had no effect on any factor versus baseline, but EPA + DHA, with and without aspirin, significantly reduced concentrations of 8 of 9 factors. Although EPA + DHA plus aspirin reduced concentrations of a subset of the factors compared to baseline, neither aspirin alone nor the combination significantly reduced the level of any analyte more robustly than EPA + DHA alone. conclusions: These data suggest that EPA + DHA has more pronounced down-regulatory effects on inflammation and angiogenesis than aspirin. The implications of these findings for the use of combined therapy for cardiovascular disease remain to be clarified.

关键词： Eicosapentaenoic Acid Docosahexaenoic Acid Lipid Mediators Fatty Acids Angiogenesis Hemostasis Platelet Function cytokines Aspirin

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声空化期间产生核发射的证据

激光与光电子学进展 2002年第5期39卷 3-10页

作者： R.P.Taleyarkhan c.D.West J.S.cho R.T.LaheyJr R.I.Nigmatulin R.c.block 晓晨罗山橡树岭国家实验室橡树岭联合大学俄罗斯科学院Ufa-Baskortostan分院 Rensselaer工业大学

在以氘代丙酮的空化实验中,探测到高于背景水平的氘衰变活动.此外,还观察到近2.5 MeV的中子发射证据,有如氘-氘聚变反应.以普通丙酮进行的受控实验不会产生氘衰变活动或中子发射.流体动力学冲击程序模拟支持上述观察结果,表明具有高度... 详细信息

在以氘代丙酮的空化实验中,探测到高于背景水平的氘衰变活动.此外,还观察到近2.5 MeV的中子发射证据,有如氘-氘聚变反应.以普通丙酮进行的受控实验不会产生氘衰变活动或中子发射.流体动力学冲击程序模拟支持上述观察结果,表明具有高度压缩、超热(106~107 K)气泡内爆条件,与核聚变反应所需的条件相同.

关键词：声空化期间空化实验核聚变汽泡内爆

阉牛以蒸汽压片玉米为基础的肥育日粮中湿玉米淀粉渣和蛋白质的最佳添加水平

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中国畜牧兽医 2006年第9期33卷 I0035-I0035页

作者： H.c.block 高雪张晓辉

本试验评价湿玉米淀粉渣能否提高育肥牛的生产性能,试验牛提供必需的可降解吸收蛋白(DIP)。试验阉牛360头(初始体重=288±11kg),采用不完全4×3因子的试验处理安排,将试验牛按完全随机设计分配到36个圈舍中,每个处理有4个重复。育肥牛... 详细信息

本试验评价湿玉米淀粉渣能否提高育肥牛的生产性能,试验牛提供必需的可降解吸收蛋白(DIP)。试验阉牛360头(初始体重=288±11kg),采用不完全4×3因子的试验处理安排,将试验牛按完全随机设计分配到36个圈舍中,每个处理有4个重复。育肥牛饲喂以蒸汽压片玉米为基础的肥育日粮,试验期166d。试验组添加湿玉米淀粉渣(分别占日粮干物质的0％、20％、30％或40％),并通过添加尿素作为DIP提供cP(分别占日粮干物质的13．0％、13．7％或14．4％)。不添加湿玉米淀粉渣(0％)的对照组,日粮中cP占13．7％；添加40％湿玉米淀粉渣的处理组,日粮中蛋白质饲粮分别占13．7％和14．4％。不添加湿玉米淀粉渣(0)的对照组,日粮中DIP的终浓度为9．0％,添加20％湿玉米淀粉渣的处理组,日粮中DIP的终浓度分别为8．7％、9．5％、10．2％；添加30％湿玉米淀粉渣的处理组,日粮中DIP的终浓度分别为9．0％、9．7％和10．3％；添加40％湿玉米淀粉渣的处理组,日粮中DIP的终浓度分别为10．0％和10．6％。热胴体重、平均日增重(ADG)、干物质摄入量(DMI)和饲料转化率(G：F)与湿玉米淀粉渣的添加量呈二次方程关系(P≤0．05)。试验结果表明,与对照组(不添加湿玉米淀粉渣)相比,添加20％、30％和40％湿玉米淀粉渣的处理组ADG分别增加7％、6％、3％,DMI分别增加4％、5％、5％。添加20％、30％和40％湿玉米淀粉渣处理组的饲料率分别是对照组的102％、101％、98％。随着DIP增加,热胴体重、平均日增重、饲料转化率呈线性增长关系(P≤0．05)。对20％和30％处理组DIP的非线性分析表明,对于平均日增重,DIP浓度为干物质的9．6％；对于饲料转化率,DIP浓度为干物质的9．2％。相应地,20％湿玉米淀粉渣组,日粮中cP含量分别达到14．6％、14．3％、30％湿玉米淀粉渣组,日粮中cP含量分别达到14．8％、14．5％。背膘厚、大理石花纹、眼肌面积和USDA标准胴体分级不受湿玉米淀粉渣或粗蛋白质的影响(P=0．12-0．99)。结果表明,在阉牛肥育日粮中,添加日粮干物质20％的湿玉米淀粉渣,能获得最大的ADG和G：F。在本试验中,DIP需求量平均占日粮干物质的9．4％。

关键词：肉牛蛋白质蒸汽压片玉米湿玉米淀粉渣

ENVIRONMENTAL PROBLEMS OF INDUSTRIALISED cOUNTRIESA Joint Symposium of the British Ecological Society and the Ecological Society of china

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生态学报 1990年第1期 4-6页

作者： A.D.Bradshaw,W.block Department British Antarctic Survey N.E.R.c. High cross Madingley Rood cambridge cB3 OET of Environmental＆Evolutionary Biology University of Liverpool P.O. Box 147 Liverpool L64 3BX

The United Kingdom and the People's Republic of china have very different *** the United Kingdom, industrial development began early, in the 18th century, and was swept along by the tide of riches that it generated, in a way that damage to the environment was disregarded and pollutants accepted as inevitable-"where there's muck,there's monev"But all this stimulated. by degrees. an.(?)

关键词： ENVIRONMENTAL PROBLEMS OF INDUSTRIALISED cOUNTRIESA Joint Symposium of the British Ecological Society and the Ecological Society of china

Novel block chain Technique for Data Privacy and Access Anonymity in Smart Healthcare

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Intelligent Automation & Soft computing 2023年第1期35卷 243-259页

作者： J.Priya c.Palanisamy Department of Information Technology Bannari Amman Institute of TechnologyErode638401TamilnaduIndia

The Internet of Things (IoT) and cloud computing are gaining popularity due to their numerous advantages, including the efficient utilization of internetand computing resources. In recent years, many more IoT applications have beenextensively used. For instance, Healthcare applications execute computations utilizing the user’s private data stored on cloud servers. However, the main obstaclesfaced by the extensive acceptance and usage of these emerging technologies aresecurity and privacy. Moreover, many healthcare data management system applications have emerged, offering solutions for distinct circumstances. But still, theexisting system has issues with specific security issues, privacy-preserving rate,information loss, etc. Hence, the overall system performance is reduced significantly. A unique blockchain-based technique is proposed to improve anonymityin terms of data access and data privacy to overcome the above-mentioned ***, the registration phase is done for the device and the user. After that, theGeo-Location and IP Address values collected during registration are convertedinto Hash values using Adler 32 hashing algorithm, and the private and publickeys are generated using the key generation centre. Then the authentication is performed through login. The user then submits a request to the blockchain server,which redirects the request to the associated IoT device in order to obtain thesensed IoT data. The detected data is anonymized in the device and stored inthe cloud server using the Linear Scaling based Rider Optimization algorithmwith integrated KL Anonymity (LSR-KLA) approach. After that, the Time-stamp-based Public and Private Key Schnorr Signature (TSPP-SS) mechanismis used to permit the authorized user to access the data, and the blockchain servertracks the entire transaction. The experimental findings showed that the proposedLSR-KLA and TSPP-SS technique provides better performance in terms of higherprivacy-preserving rate, lower info

关键词： Adler 32 hashing algorithm linear scaling based rider optimization algorithm with integrated KL anonymity(LSR-KLA) timestamp-based public and private key schnorr signature(TSPP-SS) blockchain internet of things(IoT) healthcare

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共识之美区块链经济的全景与未来