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Open Journal of Therapy and Rehabilitation 2015年第1期3卷 14-22页

作者： Wiliam César Alves Machado Juarez de Souza Pereira Nébia.Maria Almeida de Figueiredo Manoel Francisco de Souza Pereira Teresa Tonini Luciana Krauss Rezende Federal University of the State of Rio de Janeiro Rio de Janeiro Brazil Pontifical Catholic University of Rio de Janeiro Rio de Janeiro Brazil Federal University of Itajubá Itajubá Brazil

Deaf people face communication difficulties in health units because of the lack of preparedness of health care professionals to deal with these patients. Objective: To identify how physical rehabilitation professionals associated with a regional public unit in the south central region of Rio de Janeiro State, Brazil interact with deaf patients. Method: Data were analyzed through descriptive statistics in the Statistical Package for Social Sciences (SPSS) software version 18. Results: Results showed that: 15.1% (5) of the team members did not know the Brazilian Sign Language (Libras) and required help in their interaction with deaf patients;12.1% (4) never assisted deaf patients;18.2% (6) used writing and gestures;21.2% (7) resorted to lip-reading or gestures;3.1% (1) spoke slowly;6.1% (2) used mime;15.1% (5) used the Brazilian Sign Language;9.1% (3) did not respond. Conclusion: Most of these professionals are not prepared to satisfactorily interact with deaf patients. They use improvised strategies to assist the deaf clientele, demonstrating that the planning and implementation of regular courses in sign language are fundamental in order to assist these patients effectively.

关键词： Deafness Rehabilitation Unit Sign Language

有症状毛面乳房植入物相关的间变性大细胞淋巴瘤的筛查流程研究

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中华医学美学美容杂志 2024年第4期30卷 354-358页

作者：张文超谢江淼夏泽楠张明子龙笑王晓军曾昂中国医学科学院北京协和医院整形外科北京100730

目的探讨有症状毛面乳房植入物相关的间变性大细胞淋巴瘤临床筛查流程, 为毛面乳房植入物患者的管理提供经验。方法回顾性纳入2019年1月至2021年9月北京协和医院整形外科收治有症状毛面乳房植入物患者23例, 年龄29~52岁, 平均36.2岁。... 详细信息

目的探讨有症状毛面乳房植入物相关的间变性大细胞淋巴瘤临床筛查流程, 为毛面乳房植入物患者的管理提供经验。方法回顾性纳入2019年1月至2021年9月北京协和医院整形外科收治有症状毛面乳房植入物患者23例, 年龄29~52岁, 平均36.2岁。所有患者均同意手术取出假体, 术前或术中对假体周围积液、包膜组织行细胞学、流式细胞仪、免疫组织化学检查, 完善间变性大细胞淋巴瘤筛查流程。结果 23例患者均表现为单侧乳房假体周围积液, 积液量20~130 ml, 其中合并包膜挛缩者7例。术中完整取出假体及周围包膜组织, 假体周围积液及包膜组织病理检测均未发现恶性肿瘤细胞, 间变性大细胞淋巴瘤(CD 30、ALK)病理学筛查结果均为阴性。术后无出血、感染、伤口裂开等并发症。结论对有症状乳房毛面假体植入患者开展个性化临床筛查流程。重视影像学检查、病理检查。

关键词：假体植入毛面乳房植入物筛查间变性大细胞淋巴瘤 T细胞非霍奇金淋巴瘤

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别克GL8商务车中控门锁故障诊断与排除

汽车电器 2007年第4期 46-47页

作者：杨庆彪广州白云工商高级技工学校 510450

故障车型别克GL8商务车，上海通用汽车制造厂2004年生产，已行驶约20万km。

关键词：别克GL8 故障诊断商务车中控门锁汽车制造厂上海通用行驶

bia.10-2474药物临床研究中5例健康受试者神经系统损害及死亡事件的启示

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协和医学杂志 2018年第3期9卷 256-260页

作者：陈霞首都医科大学附属北京天坛医院国家神经系统疾病临床医学研究中心-临床试验中心北京100050

2016年1月,在法国进行的bia.10-2474Ⅰ期临床试验中,1名健康受试者在给药后发生脑死亡。为了探寻事件原因,尽可能从系统上降低类似悲剧重现的风险,本文根据bia.10-2474专家调查组的报告,从药物作用机制、临床前研究发现、临床研究设计... 详细信息

2016年1月,在法国进行的bia.10-2474Ⅰ期临床试验中,1名健康受试者在给药后发生脑死亡。为了探寻事件原因,尽可能从系统上降低类似悲剧重现的风险,本文根据bia.10-2474专家调查组的报告,从药物作用机制、临床前研究发现、临床研究设计和实施等方面梳理了这个悲剧性事件的前因后果,并获得以下启示:第一,应在药物进入临床研发前根据已获得的研究数据和同类药物的相关信息审慎决策,以便提高研发成功率,规避不必要的风险;第二,研究设计既要考虑药物的临床前安全性特征,还要考虑药效特征,在兼顾受试者安全的前提下达成试验的科学目的;第三,高风险新药早期临床研究应始终保持高度警惕性,不放过任何可能提示药物风险的信号,遇到问题全面分析,保守处理。

关键词：药物临床研发首次人体研究风险控制

Pró-Saúde and PET-Saúde in the Context of Reorientation Policy of Health Professions Training

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Health 2015年第13期7卷 1800-1805页

作者： Ana Maria Gomes dos Santos Maria José Medeiros da Fonseca Fernanda Fayane C. Belarmino Adriana Vitória dos Santos Fábia.Barbosa de Andrade City Health Department Municipal Government Santa Cruz Brazil Faculty of Health Sciences of Trairi (FACISA) Federal University of Rio Grande do Norte (UFRN) Santa Cruz Brazil

The health education has been a topic discussed throughout Brazil, as the country is experiencing a period of expansion of higher education and it needs to give quality. So they were implanted two federal programs to allow that health students to approach their professional reality to make them capable of full mode. The paper aims to discuss the experience of the participating members of these programs for professional reorientation. The study is exploratory and descriptive conducted with participants of the programs in the city of Santa Cruz, Rio Grande do Norte, Brazil, in the year 2014. This study aims to present an experience report from the experience of the mentors in Reorientation National Program for Health Professional Training (Pró-Saúde), associated with the Labor Education Program for Health (PET-Saúde) at the Federal University of Rio Grande do Norte (UFRN)/Sciences College of Trairi (FACISA), with emphasis on the reorientation of professional practice, provided by integrating teaching-service and community as well as exchange of knowledge between tutors, mentors and students participating in the project, from the development of interdisciplinary activities, giving the opportunity to reflect on these actions and services offered based on the epidemiological analysis provided by research, intervening in this reality.

关键词： Health Education Education Community Learning Students Family Health

异丙酚对内毒素诱导人脐静脉内皮细胞过氧亚硝基阴离子生成的影响

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中华麻醉学杂志 2009年第8期29卷 733-736页

作者：肖建斌高巨周罗晶招伟贤广州中医药大学附属第二医院(广东省中医院)麻醉科 510120 广州中医药大学附属第二医院(广东省中医院)临床流行病研究室 510120

目的探讨异丙酚对内毒素诱导人脐静脉内皮细胞过氧亚硝基阴离子（ONOO^-）生成的影响。方法培养至活细胞计数大于95％的人脐静脉内皮细胞，随机分为7组（n=5），对照组（C组）不给予任何处理；LPS0.1组、LPS1组和LPS10组分别加入内毒素... 详细信息

目的探讨异丙酚对内毒素诱导人脐静脉内皮细胞过氧亚硝基阴离子（ONOO^-）生成的影响。方法培养至活细胞计数大于95％的人脐静脉内皮细胞，随机分为7组（n=5），对照组（C组）不给予任何处理；LPS0.1组、LPS1组和LPS10组分别加入内毒素（LPS）至终浓度为0．1、1和10μg／ml，于37℃5％CO2培养箱中孵育6h；P4＋LPS10组和P40＋LPS10组预先加入异丙酚至终浓度为4、40μg／ml，I40＋LPS10组预先加入脂质溶剂Introlipid至终浓度为40μg／ml，于37℃5％CO2培养箱中孵育30min，再分别加入LPS至终浓度为10μg／ml，于培养箱中继续孵育6h。孵育6h时，测定细胞活力和乳酸脱氢酶（LDH）释放率；采用免疫组化法和Westernblot法测定硝基酪氨酸蛋白（NT）表达。结果与C组比较，其余各组细胞活力降低，内皮细胞NT表达上调，LPS1组、LPS10组、I40＋LPS10组、P4＋LPS10组和P40＋LPS10组LDH释放率升高（P〈0．01）；与LPS0.1组比较，LPS1组细胞活力、LDH释放率和内皮细胞NT表达差异无统计学意义（P〉0．05），LPS10组细胞活力降低，LDH释放率升高，内皮细胞NT表达上调（P〈0．01）；与LPS10组比较，I40＋LPS10组细胞活力、LDH释放率和内皮细胞NT表达差异无统计学意义（P〉0．05），P4＋LPS10组和P40＋LPS10组细胞活力升高，LDH释放率降低，内皮细胞NT表达下调（P〈0．01）。结论异丙酚可通过抑制ONOO^-的生成，减轻内毒素诱导人脐静脉内皮细胞损伤。

关键词：二异丙酚脂多糖类内皮细胞亚硝基化合物

Evidence for metasomatic mantle carbonatitic magma extrusion in Mesoproterozoic ore-hosting dolomite rocks in the middle Kunyang rift, central Yunnan, China

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Progress in Natural Science:Materials International 2008年第8期18卷 965-974页

作者： Yongbei Zhanga,b,c, Hua bia.*, Longshi Yua, Shihua Sunc, Jiaxiang Qiub, Chengyan Xub, Hao Wang b, Renjing Wang b a The Department of Resources, Environment and Tourism, Hainan Normal University, No. 432, Yinpo Road, Longshepo, Haikou 57000, China b Key Laboratory of Mineral Resources, Institute of Geology and Geophysics, Chinese Academy of Sciences, Beijing 100029, China c Faculty of Earth Sciences, China University of Geosciences, Wuhan 470074, China The Department of Resources Environment and Tourism Hainan Normal University No. 432 Yinpo Road Longshepo Haikou 57000 China Key Laboratory of Mineral Resources Institute of Geology and Geophysics Chinese Academy of Sciences Beijing 100029 China Faculty of Earth Sciences China University of Geosciences Wuhan 470074 China

The Kunyang rift lying on the western margin of the Yangtze platform is a rare Precambrian Fe-Cu mineralization zone. WudingLufeng basin that is an important part of the zone is located on the west edge in the middle of the rift. The most important ore-hosting rocks are Mesoproterozoic dolomite rocks in the basin controlled by a ring fracture system, which is a fundamental structure of the basin. Plenty of silicate minerals and acicular apatite, feldspar phenocrysts and small vesicular, flown line and flown plane structures, melt inclusion and high temperature fluid inclusion found in most ore-hosting dolomites suggest that this kind of rocks could not be sedimentary dolomite, marble or hydrothermal carbonate rocks. The Zr/Hf and Nb/Ta values of the rocks are identical with those of associated mantle-derived rocks, and vary widely. For the monomineral dolomite, d18OSMOW‰ = +5.99 to +18.4 and d13CPDB‰ = à3.01 to +0.94, which fall within the range for all carbonatitic volcanic rocks of the world. As for the accessory minerals, the values of d18OSMOW‰ of magnetite (=+3.47 to +5.99‰) are close to that of the mantle (<5.7%), and the d34S‰ values of sul?des (à5.09 to +5.78, averaging +1.50) are close to that of meteorite. For all the ore-bearing dolomite rocks, eNd = +0.19 to +2.27, and the calculated ISr = 0.699143, while for the associated mantle-derived rocks, eNd = +3.18 to +3.72. All the data suggest that the mineral assemblage is not only igneous but also of metasomatic mantle origin. And the presence of acicular apatite indicates that the rocks were formed by magma rapidly cooling. And the phenocryst texture and vesicular, flown and ropy and pyroclastic structures suggest that the igneous rocks were extrusive. Therefore, the ore-bearing dolomite rocks are carbonatitic volcanic rocks. This conclusion implies that most iron and copper ore deposits hosted in the dolomite rocks should be of the carbonatite type.

关键词： Central Yunnan Kunyang rift Precambrian Mineralization Carbonatitite Volcanic rocks Petrogenesis Iron and copper ore deposit

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黄瓜新品种盛秋1号的选育

中国蔬菜 2011年第12期 94-96页

作者：张作标许春梅柳景兰黑龙江省农业科学院园艺分院黑龙江哈尔滨150069

盛秋1号是以自交系T1-3为母本,自交系L25-7为父本配制的黄瓜一代杂种。该品种植株长势强,主、侧蔓均结瓜,瓜长18cm左右,皮色浅绿,有光泽,白刺稀少、耐老,瓜条顺直。果肉甜嫩,清香味浓,商品性好。高抗枯萎病,抗霜霉病、白粉病、炭疽病。... 详细信息

盛秋1号是以自交系T1-3为母本,自交系L25-7为父本配制的黄瓜一代杂种。该品种植株长势强,主、侧蔓均结瓜,瓜长18cm左右,皮色浅绿,有光泽,白刺稀少、耐老,瓜条顺直。果肉甜嫩,清香味浓,商品性好。高抗枯萎病,抗霜霉病、白粉病、炭疽病。平均每667m2产量2000kg以上,耐热,适合夏秋露地栽培。

关键词：黄瓜盛秋l号一代杂种

Painful Symptomatology Reported by Dentistry Students at a Brazilian University

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Health 2015年第8期7卷 976-985页

作者： Cristiane Assuncao da Costa Cunha Iris do Ceu Clara Costa Angelo Giuseppe Roncalli Dyego Leandro Bezerra de Souza Fábia.Barbosa de Andrade Antonio Medeiros Júnior Department of Dentistry Federal University of Rio Grande do Norte(UFRN)NatalBrazil Department of Collective Health Federal University of Rio Grande do Norte(UFRN)NatalBrazil Department of Nursing Faculty of Health Sciences of Trairi(FACISA)Federal University of Rio Grande do Norte(UFRN)Santa CruzBrazil

Objectives: Identification of the level of knowledge on ergonomics principles, and application of these by dentistry students to investigate whether painful symptomatology was experienced. An-other objective is the expansion of discussions on occupational health in academic settings. Study Design and Settings: Dentistry students of the Federal University of Rio Grande do Norte, Brazil (n = 148) were surveyed using the Nordic Musculoskeletal Questionnaire to determine the severity of musculoskeletal symptoms experienced. Data were analyzed through EpiInfo 7.0 to measure central trends and variability 5for quantitative variables, absolute and relative frequencies for categorical variables, and significance between groups (confidence intervals and chisquare). Association analysis (Pearson) was also carried out. Results: Ergonomic measures were not reported by students. Within the musculoskeletal symptoms described, females were the most affected, independent of academic level. Conclusions: Positive correlations were verified between all categories and all anatomic regions (e.g., neck, lower back, wrists, hands, and shoulders). Data suggest progressive worsening of symptoms, which will eventually result in leaves of absence.

关键词： Musculoskeletal Disorders Ergonomics Health Promotion Occupational Health Health Education

The Body Suffering and Care Possibilities: A Reflective Look from the Health Economics

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Health 2016年第4期8卷 285-292页

作者： José Humberto Cardoso Resende Allan Peixoto de Assis Lucilia Feliciano Marques di Carlantônio Luiz Célio Martins Freitas Teresa Tonini Nébia.Maria Almeida de Figueiredo Luiz Carlos Santiago Universidade Federal do Estado do Rio de Janeiro (UNIRIO) Rio de Janeiro Brazil

This article aimed to show ideas about the themes: body suffering, nursing and Medical care, and Health Economics. To this end, we tried to put together a kaleidoscope of references that converged on the promotion of autonomy and empowerment and, as a strategy for action, and then we can think of what to do to alleviate the suffering of patients.

关键词： Health Economics Nursing Medicine