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Prevalence of Frailty Syndrome in the Elderly and Associated Factors in Brazil

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Health 2015年第11期7卷 1591-1599页

作者： Anna Ferla Monteiro Silva Passos Iris do Céu Clara Costa Fábia.Barbosa de Andrade Maria do Carmo Eulálio Anita Liberalesso Neri Romulo Lustosa Pimenteira de Melo Adrianna Ribeiro Lacerda Postgraduation Program in Health Sciences Federal University of Rio Grande do Norte Natal Brazil Department of Dentistry Federal University of Rio Grande do Norte Natal Brazil Nursing Faculty of Health Sciencies of Trairi/Federal University of Rio Grande do Norte Santa Cruz Brazil Department of Psychology State University of Paraíba Campina Grande Brazil Department of Educational Psychology State University of Campinas Campinas Brazil

This paper aims to identify the prevalence of frailty syndrome and its association with demographic, economic, health, psychological and functional variables in Brazilian population. The study was cross-sectional and composed of 385 elderly aged from 65 years, an average age of 73.92 years. A multivariate Poisson regression was used to check for conditions associated with frailty and to determine the prevalence (α = 0.05). The prevalence of frailty was 8.7% and pre-frailty of 50.4%. The frail and pre-frail older adults showed larger and increasing prevalence ratios for marital status, difficulty performing instrumental activities of daily living, old age, involuntary loss of feces, depression and negative affections. These results can guide the establishment of preventive measures and the development of intervention strategies aimed at minimizing the adverse effects of frailty in elderly people.

关键词： Aging Frail Elderly Frailty Frailty Syndrome

Fern extracts potentiate fluconazole activity and inhibit morphological changes in Candida species

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Asian Pacific Journal of Tropical Biomedicine 2017年第11期7卷 1025-1030页

作者： Maria A.Freitas Antonia T.L.Santos Antonio J.T.Machado Ana Raquel P.Silva Fábia.F.Campina Maria S.Costa Gioconda M.A.B.Martins Maria Flaviana B.Morais-Braga Saulo R.Tintino Irwin R.A.Menezes Jaime Ribeiro-Filho Altevir P.Medeiros Adeliana S.Oliveira Patrício B.Maracajá Henrique D.M.Coutinho Universidade Regional do Cariri-URCA Universidade Federal Rural do Semi-A′rido-UFERSA Universidade Federal do Rio Grande do Norte-UFRN Universidade Federal de Campina Grande-UFCG

Objective: To investigate the antifungal activity of the fern species Lygodium venustum(L. venustum) and Pityrogramma calomelanos(P. calomelanos) against Candida albicans and Candida tropicalis ***: The microdilution method was used to evaluate the antifungal activity, as well as the modulating effects of ethanolic extracts of these plants in combination with fluconazole. The minimum inhibitory concentration(MIC), minimum fungicide concentration and morphological changes were also ***: The extract obtained from L. venustum presented a MIC > 8 192 mg/m L, while the extract obtained from and P. calomelanos presented a MIC = 8 192 mg/m L, indicating that they present weak antifungal activity. However, combination of the extracts with Fluconazole potentiated the antifungal activity of this drug. At different experimental conditions, such as concentration of the extract and type of strain, the extracts inhibited hyphae and pseudohyphae formation, indicating that these fern species can affect the morphology of the ***: The extracts obtained from the fern species L. venustum and P. calomelanos dose not present significant antifungal activity. However, P. calomelanos potentiates the activity of fluconazole and both extracts inhibits the morphological changes in Candida species, indicating that they have potential pharmacological activity as modulators of fungal biology. Therefore, novel studies are required to characterize the interference of these extracts in the virulence and pathogenicity of Candida species as well as the potential of fern species to treat fungal infections.

关键词： Dimorphism Candida species Ferns Lygodium venustum Pityrogramma calomelanos

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基于大课堂理念的制冷工程教学模式探析

大学教育 2019年第9期 40-42页

作者：李敏凌长明叶彪广东海洋大学机械与动力工程学院

以学生为主体,以强化学生需求驱动的主动学习为目的,突破常规的以地点来定性的课堂概念,文章首次提出了以导师来定位的立体化大课堂概念。将教室、网络、实验室、实习基地、企业构筑成立体化的教学网络,形成大课堂理念的应用平台。课堂... 详细信息

以学生为主体,以强化学生需求驱动的主动学习为目的,突破常规的以地点来定性的课堂概念,文章首次提出了以导师来定位的立体化大课堂概念。将教室、网络、实验室、实习基地、企业构筑成立体化的教学网络,形成大课堂理念的应用平台。课堂随着学习需要和教学导向而改变,使理论教学与实物操作和应用围绕着学生能力培养这个中心,达到理论与实践的完美结合。实践表明这样的教学成效显著,为大工科教学模式的丰富与创新提供了新思路。

关键词：大课堂理念制冷工程需求驱动导师定位

Evaluation of the Fertility and Mortality in Women at Fertile Age

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Open Journal of Nursing 2018年第2期8卷 139-149页

作者： Thaiza G. C. da Silva Medeiros Tainara L. dos Santos Ferreira Héllyda de Souza Bezerra Julliane T. A. de Melo Thaiza Teixeira Xavier Nobre Fábia.Barbosa de Andrade Trairi Health Sciences College (FACISA in Portuguese) Rio Grande do Norte Federal University (UFRN) Santa Cruz Rio Grande do Norte Brazil

The female population is passing through many transformations as on the familiar life as for the society. This inequality among the genders reflects on the health, mainly, on the women. The women morbidity and mortality surveillance is one of the priorities of the Health Ministry. This worksheet aims to evaluate the fertile women fertility and mortality, from 10 to 49 years old, in Trairi/RN. It is descriptive, ecological and temporary, whose analysis is based on the Mortality Information System data, in a period of 5 years (2010-2014), at the Vth Public Health Regional Center (URSAP), which embraces the Trairi region, composed by 21 cities, in Rio Grande do Norte. The data processing and analysis were used by the SPSS software. It was observed the mortality coefficient with a decline from 2011 (0.84) and back to increase in 2014 (0.94). This reveals the necessity of better health actions and monitoring from other factors that may interfere on women health.

关键词： Mortality Women Health Epidemiology

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中世纪大学自治的误读与重释

高等教育研究 2017年第6期38卷 86-92页

作者：覃红霞厦门大学教育研究院福建厦门361005

在学术界,中世纪大学及其自治往往被视为大学的典范,这主要源于中世纪大学拥有的社团法人身份、特许状以及特权。但中世纪大学只是中世纪社会环境的产物,社团是中世纪特有的法律形式,其实质是特许法人。中世纪大学的特许状不是近现代意... 详细信息

在学术界,中世纪大学及其自治往往被视为大学的典范,这主要源于中世纪大学拥有的社团法人身份、特许状以及特权。但中世纪大学只是中世纪社会环境的产物,社团是中世纪特有的法律形式,其实质是特许法人。中世纪大学的特许状不是近现代意义上大学与政府之间的契约,而是身份的认同协议,其权利的实质是特许权。研究中世纪大学,其意义不在于回到中世纪大学,而是为了更加客观而清晰地认识中西方大学的传统,从而建构具有中国特色的现代大学制度。

关键词：社团法人特许状特权中世纪大学

Oral Health and Self-Perception in the Elderly

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Health 2014年第21期6卷 3045-3053页

作者： Walda Viana Brígido de Moura Iris do Ceu Clara Costa Fábia.Barbosa de Andrade Tainara Lorena dos Santos Ferreira Andréa Silvia Walter de Aguiar Gabriela Eugenio de Sousa Furtado Maria Eneide Leitao de Almeida Department of Dentistry Federal University of Ceará(UFC)FortalezaBrazil Department of Dentistry Federal University of Rio Grande do Norte(UFRN)NatalBrazil Faculty of Health Sciences of Trairi(FACISA) Federal University of Rio Grande do Norte(UFRN)Santa CruzBrazil

Background: Investigating self-perception of oral health among the elderly may contribute towards changing public health and assistance policies in the area. Methods: The present study assessed the oral health status (tooth decay, need for treatment, periodontal status, use of and need for dental prosthesis, soft tissue alterations and self-perception of oral health) of 102 elderly people from two community groups in Fortaleza, Ceará State, Brazil. Results: Mean age was 69.9 years and 82.4% were female. Mean DMFT was 30.17 with a predominant missing component;63.7% were edentulous. Regarding prosthesis, 29.4% and 67.6% of elderly patients did not use upper and lower dentures respectively, while 66.7% and 78.4% required some type of upper and lower prosthesis respectively. Among valid sextants, 44.3% presented dental calculus and 34.3% presented loss of attachment from 6 to 8 mm. Soft tissue alterations were found in 58.8%. Despite of precarious clinical conditions and dental treatment needs, good oral health perception was found (49%), as well as satisfaction with the appearance of teeth and gums (60.8%). Conclusion: Subjects displayed unsatisfactory oral health conditions, accumulated over time and resulting from the lack of policies favoring this age group. There is a need for oral rehabilitation that enables the recovery of function and esthetics among the elderly, restoring their self-esteem and improving social interaction.

关键词： Oral Health The Elderly Epidemiology Self-Image

Clinical Follow-Up Nursing Quality in Child Health

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Health 2015年第10期7卷 1235-1242页

作者： Fábia.Barbosa de Andrade Tainara Lorena dos Santos Ferreira Tiago Jose Barbosa de Andrade Jéssica Isabelle dos Santos Dutra Dídia de Oliveira Pereira Brenda Kalyny Silva Brenda Kalyny Silva Ingrid Katianne Marques Araújo Faculty of Health Sciences of Trairi(FACISA) Federal University of Rio Grande do Norte(UFRN)Santa CruzBrazil University Center of Joao Pessoa(UNIPe) Joao PessoaBrazil

Objective: The present work aims to evaluate the impact of the activities of nursing consultations on health conditions of children served in Clínica de Enfermagem Salvando Vidas com Educa??o. Methods: This is an exploratory, descriptive study with a quantitative approach, realized from January through December 2012, at the Clínica de Enfermagem (Nursing Clinic), in the Santa Cruz County, Rio Grande do Norte’s countryside, Brazil. Results: The obtained results showed a significant correlation between the type of pathology and final treatment proven by the value of p = 0.000;as for assessed 60%, more than half were discharged;the most prevalent diseases were the association between cutaneous and gastric with 11% who were discharged and, lastly, the association between gastric and respiratory with 7% discharged. Conclusion: Thus, the activities developed by the project are not restricted to the examination during the nursing consultation, since educational activities are planned from the data obtained in those consultations.

关键词： Child Nursing School Care

Factors influencing the failure of interferon-free therapy for chronic hepatitis C:Data from the Polish EpiTer-2 cohort study

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World Journal of Gastroenterology 2021年第18期27卷 2177-2192页

作者： Ewa Janczewska Mateusz Franciszek Kołek Beata Lorenc Jakub Klapaczyński Magdalena Tudrujek-Zdunek Marek Sitko Włodzimierz Mazur Dorota Zarębska-Michaluk Iwona Buczyńska Dorota Dybowska Agnieszka Czauż-Andrzejuk Hanna Berak RafałKrygier Jerzy Jaroszewicz Jolanta Citko Anna Piekarska Beata Dobracka Łukasz Socha Zbigniew Deroń Łukasz Laurans Jolanta bia.kowska-Warzecha Olga Tronina Brygida Adamek Krzysztof Tomasiewicz Krzysztof Simon Malgorzata Pawłowska Waldemar Halota Robert Flisiak Department of Basic Medical Sciences The School of Health Sciences in BytomMedical University of SilesiaBytom 41-902Poland Department of Animal Physiology Faculty of BiologyUniversity of WarsawWarszawa 02-096Poland Pomeranian Center of Infectious Diseases Medical University GdańskGdańsk 80-214Poland Department of Internal Medicine and Hepatology Central Clinical Hospital of the Ministry of Internal Affairs and AdministrationWarszawa 02-507Poland Department of Infectious Diseases Medical University of LublinLublin 20-081Poland Department of Infectious and Tropical Diseases Jagiellonian UniversityKraków 30-688Poland Clinical Department of Infectious Diseases Medical University of Silesia in KatowiceChorzów 41-500Poland Department of Infectious Diseases Jan Kochanowski University KielceKielce 25-369Poland Department of Infectious Diseases and Hepatology Medical University WrocławWrocław 51-149Poland Department of Infectious Diseases and Hepatology Ludwik Rydygier Collegium Medicum in Bydgoszcz Faculty of Medicine Nicolaus Copernicus University in ToruńBydgoszcz 85-030Poland Department of Infectious Diseases and Hepatology Medical University of BiałystokBiałystok 15-540Poland One-Day Department Hospital for Infectious Diseases in WarsawWarszawa 01-201Poland Outpatient Clinic State University of Applied Sciences in KoninKonin 62-510Poland Department of Infectious Diseases and Hepatology Medical University of Silesia in KatowiceBytom 41-902Poland Department of Medical Practice of Infections Regional HospitalOlsztyn 10-561Poland Department of Infectious Diseases and Hepatology Medical University ofŁódźŁódź90-419Poland MedicalSpec Center Wrocław 53-428Poland Department of Infectious Diseases Hepatology and Liver TransplantationPomeranian Medical UniversitySzczecin 71-455Poland Ward of Infectious Diseases and Hepatology Biegański Regional Specialist HospitalŁódź91-347Poland Infectious and Liver Diseases Clinic Multidisciplinary Regional HospitalGorzów Wielkopolski 66-400Poland Dep

BACKGROUND The introduction of direct-acting antiviral drugs into clinical practice has revolutionized the treatment of chronic hepatitis C,making it highly effective and safe for ***,few researchers have analyzed the factors causing therapy failure in some *** To analyze factors influencing the failure of direct antiviral drugs in the large,multicenter EpiTer-2 cohort in a real-world *** The study cohort consisted of patients with chronic hepatitis C treated at 22 Polish centers from *** collected from the online EpiTer-2 database included the following:hepatitis C virus(HCV)genotype,stage of fibrosis,hematology and liver function parameters,Child-Turcotte-Pugh and Model for End-stage Liver Disease scores,prior antiviral therapy,concomitant diseases,and drugs used in relation to hepatitis B virus(HBV)and/or human immunodeficiency virus(HIV)*** events observed during the treatment and follow-up period were *** standard and machine learning methods were used for statistical *** During analysis,12614 patients with chronic hepatitis C were registered,of which 11938(mean age:52 years)had available sustained virologic response(SVR)data[11629(97%)achieved SVR and 309(3%)did not].Most patients(78.1%)were infected with HCV genotype *** cirrhosis was diagnosed in 2974 patients,while advanced fibrosis(F3)was diagnosed in 1717 *** included patients with features of hepatic failure at baseline[ascites in 142(1.2%)and encephalopathy in 68(0.6%)patients].The most important host factors negatively influencing treatment efficacy were liver cirrhosis,clinical and laboratory features of liver failure,history of hepatocellular carcinoma,and higher body mass *** viral factors,genotype 3 and viral load also exerted an influence on treatment *** statistical analysis revealed that treatment ineffectiveness seemed to be influenced by the male sex,which was not confirmed

关键词： Advanced liver disease Chronic hepatitis C Direct-acting antiviral drugs Sustained virologic response Interferon-free therapy Antiviral therapy

A Proposal of Oat Productivity Simulation by Meteorological Elements,Growth Regulator and Nitrogen

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American Journal of Plant Sciences 2017年第9期8卷 2101-2118页

作者： Anderson Marolli José Antonio Gonzalez da Silva Osmar Bruneslau Scremin Rúbia.Diana Mantai Ana Paula Brezolin Trautmann Angela Teresinha Woschinski de Mamann Roberto Carbonera Adriana Roselia Kraisig Cleusa Adriane Menegassi bia.chi Krüger Emilio Ghisleni Arenhardt Department of Exact Sciences and Engineering Regional University of the Northwestern of Rio Grande do Sul State(UNIJUí)IjuiBrazil Department of Agrarian Studies Regional University of the Northwestern of Rio Grande do Sul State(UNIJUí)IjuiBrazil Department of Crop Plants Federal University of Rio Grande do Sul(UFRGS)Porto AlegreBrazil

The simulation of oat grain productivity does not contemplate the use of efficient models that involve important management with meteorological elements. The objective of the study is to propose a mathematical model capable of simulating the oat grain productivity through the management of nitrogen and growth regulator with variables related to the plant and to meteorological elements. In this study, two experiments were conducted in the years of 2013, 2014 and 2015: one to quantify biomass productivity and another to determine grain productivity and lodging at the management doses of nitrogen and growth regulator. The experimental design was a randomized block with four replications in a 4 × 3 factorial scheme for 0, 200, 400 and 600 mL·ha-1 growth regulator doses and 30, 90 and 150 kg·ha-1 nitrogen doses, respectively. During the crop cycles, the meteorological variables thermal sum, radiation and rainfall were quantified. The mathematical model proposed, which combines polynomial regression of the harvest index with multiple linear regression of the biological productivity, is efficient in the simulation of oat grains productivity with the use of growth regulator, nitrogen and meteorological elements. Thus, it adds to the conventional models of simulation and becomes an aid tool for making decisions regarding the management of oats culture.

关键词： Avena sativa Biomass Lodging Trinexapac-Ethyl Regression