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Optimization of performance of the KM2A full array using the Crab Nebula

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Chinese Physics C 2024年第6期48卷 169-178页

作者：曹臻 F.Aharonian 安琪阿西克古白云翔包逸炜 D.Bastieri 毕效军毕玉江蔡金庭曹晴曹文羽曹喆常进常劲帆陈尚明陈恩生陈亮陈林陈龙陈明君陈玛丽陈起辉陈素弘陈天禄陈阳程宁程耀东崔明阳崔树旺崔晓红崔昱东戴本忠代洪亮戴子高单增罗布 D.della Volpe 董绪强段凯凯樊军辉范一中方军方堃冯存峰封莉冯少辉丰晓婷冯有亮 S.Gabici 高博高川东高林青高启高卫高伟康葛茂茂耿利斯 G.Giacinti 龚光华苟全补顾旻皓郭福来郭晓磊郭义庆郭莹莹韩毅昂何会海贺昊宁何佳银何新波何钰 M.Heller 贺远强侯博文侯超侯贤胡红波胡铨胡世聪黄代绘黄天奇黄文俊黄性涛黄晓渊黄勇黄志成季筱璐贾焕玉贾康江琨姜晓巍姜泽军金敏康明铭柯通 D.Kuleshov.K.Kurinov 李兵兵李澄李骢李丹李飞李海波李会财李华阳李军李剑李捷李凯李文龙李文莲李秀荣李昕李一卓李哲黎卓梁恩维梁云峰林苏杰刘冰刘成刘栋刘虎刘海东刘佳刘江来刘金艳刘茂元柳若愚刘四明刘伟刘怡刘以农鲁睿罗晴吕洪魁马伯强马玲玲马欣华毛基荣闵振 W.Mitthumsiri 穆慧君南云程 A.Neronov 区子维庞彬宇 P.Pattarakijwanich 裴致远齐孟尧祁业情乔冰强秦家军 D.Ruffolo A.Sáiz D.Semikoz 邵澄宇邵琅 O.Shchegolev 盛祥东舒富文宋慧超 yu.V.Stenkin V.Stepanov 苏扬孙秦宁孙晓娜孙志斌谭柏轩唐庆文唐泽波田文武王超王昌贝王广威王洪光王惠惠王建成汪凯王利苹王玲玉王培汉王冉王为王祥高王祥玉王阳王玉东王岩谨王忠海王仲翔王振王铮韦大明魏俊杰魏永健文韬吴超勇吴含荣武莎吴雪峰吴雨生席邵强夏捷夏君集项光漫肖迪泫肖刚辛广广辛玉良邢祎熊峥徐东莲徐仁峰徐仁新徐伟立薛良闫大海颜景志颜田杨朝文杨帆杨冯帆杨何文杨佳盈杨莉莉杨明洁杨睿智杨深邦姚玉华姚志国叶一锰尹丽巧尹娜游晓浩游智勇于艳红袁强岳华曾厚敦曾婷轩曾玮查敏张彬彬张丰张海明张恒英张建立张丽霞张力张鹏飞张佩佩张瑞张少博张少如张寿山张潇张笑鹏张云峰张毅张勇赵兵赵静赵雷赵立志赵世平郑福周斌周浩周佳能周猛周平周荣周勋秀祝成光祝凤荣朱辉朱科军左雄 LHAASO Collaboration Key Laboratory of Particle Astrophyics&Experimental Physics Division&Computing Center Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Beijing 100049China Tianfu Cosmic Ray Research Center Chengdu 610000China Dublin Institute for Advanced Studies 31 Fitzwilliam Place2 DublinIreland Max-Planck-Institut for Nuclear Physics P.O.Box 10398069029 HeidelbergGermany State Key Laboratory of Particle Detection and Electronics China University of Science and Technology of China Hefei 230026China School of Physical Science and Technology&School of Information Science and Technology Southwest Jiaotong UniversityChengdu 610031China School of Astronomy and Space Science Nanjing UniversityNanjing 210023China Center for Astrophysics Guangzhou UniversityGuangzhou 510006China Hebei Normal University Shijiazhuang 050024China Key Laboratory of Dark Matter and Space Astronomy&Key Laboratory of Radio Astronomy Purple Mountain ObservatoryChinese Academy of SciencesNanjing 210023China Tsung-Dao Lee Institute&School of Physics and Astronomy Shanghai Jiao Tong UniversityShanghai 200240China Key Laboratory for Research in Galaxies and Cosmology Shanghai Astronomical ObservatoryChinese Academy of SciencesShanghai 200030China Key Laboratory of Cosmic Rays(Tibet University) Ministry of EducationLhasa 850000TibetChina National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China School of Physics and Astronomy(zhuhai)&School of Physics(Guangzhou)&Sino-French Institute of Nuclear engineering and Technology(zhuhai) Sun Yat-sen UniversityZhuhai 519000&Guangzhou 510275China School of Physics and Astronomy Yunnan UniversityKunming 650091China Département de Physique Nucléaire et Corpusculaire Facultéde SciencesUniversitéde Genève24 Quai Ernest Ansermet1211 GenevaSwitzerland Institute of Frontier and Interdisciplinary Science Shandong UniversityQingdao 266237China APC Universit'e Paris Cit'eCNRS/IN2P3CEA/IRFUObservat

The full array of the Large High Altitude Air Shower Observatory(LHAASO)has been in operation since July *** its kilometer-square array(KM2A),we optimized the selection criteria for very high and ultrahigh energyγ-rays using data collected from August 2021 to August 2022,resulting in an improvement in significance of the detection in the Crab Nebula of approximately 15%,compared with that of previous *** the implementation of these new selection criteria,the angular resolution was also significantly improved by approximately 10%at tens of *** aspects of the full KM2A array performance,such as the pointing error,were also calibrated using the Crab *** resulting energy spectrum of the Crab Nebula in the energy range of 10-1000 TeV are well fitted by a log-parabola model,which is consistent with the previous results from LHAASO and other experiments.

关键词： γ-ray Crab Nebula significance

WAVE RESISTANCE OF WAVE-PIERCING CATAMARANS

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Journal of Hydrodynamics 2000年第4期12卷 88-98页

作者： lu, X.P. Huang, y. Shi, z.K. Coll. of Traffic Sci. and eng. Huazhong Univ. of Sci. and Technol. Wuhan 430074 China

Present paper researches the theoretical method for calculating the wave resistance of wave-piercing catamaran. As an example the wave resistance of a wave-piercing catamaran is calculated. The comparison among the theoretical calculation results, the model test results and the graphic evaluation results shows the efficiency of present theoretical method. Finally the wave resistance regulation of wave-piercing catamarans is investigated based on the theoretical method.

关键词： Ships

An efficient strategy for producing a stable, replaceable, highly efficient transgene expression system in silkworm, Bombyx mori

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An efficient strategy for producing a stable, replaceable, h...

Lattice vibrations and Raman scattering in two- dimensional layered materials beyond graphene

第十二届家（柞）蚕遗传育种暨良种繁育学术研讨会

作者： Long D lu W zhang y bi L Xiang z zhao A State Key Laboratory of Silkworm Genome biology Key Laboratory for Sericulture Functional Genomics and Biotechnology of Agricultural Ministry Southwest University Guangxi Research Academy of Seficultural Science

We developed an efficient strategy that combines a method for the post-integration elimination of all transposon sequences, a site-specific recombination system, and an optimized fibroin H-chain expression system to produce a stable, replaceable, highly efficient transgene expression system in the silkworm（Bombyx mori） that overcomes the disadvantages of random insertion and post-integration instability of transposons. Here, we generated four different transgenic silkworm strains, and of one the transgenic strains, designated TS1-Rg G2, with up to 16%（w/w） of the target protein in the cocoons, was selected. The subsequent elimination of all the transposon sequences from TS1-RgG2 was completed by the heat-shock-induced expression of the transposase in vivo. The resulting transgenic silkworm strain was designated TS3-g2 and contained only the att P-flanked optimized fibroin H-chain expression cassette in its genome. A phi C31/att-system-based recombinase-mediated cassette exchange（RMCE） method could be used to integrate other genes of interest into the same genome locus between the att P sites in TS3-g2. Controlling for position effects with phi C31-mediated RMCE will also allow the optimization of exogenous protein expression and fine gene function analyses in the silkworm. The strategy developed here is also applicable to other lepidopteran insects, to improve the ecological safety of transgenic strains in biocontrol programs.

关键词：

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Nano Research 2016年第12期9卷 3559-3597页

作者： Xin lu Xin luo Jun zhang Su ying Quek Qihua Xiong Division of Physics and Applied Physics School of Physical and Mathematical Sciences Nanyang Technological University Singapore 637371 Singapore Department of Physics National University of Singapore 2 Science Drive 3 Singapore 117551 Singapore Centre for Advanced 2D Materials National University of Singapore 6 Science Drive 2 Singapore 117546 Singapore State Key Laboratory of Superlattices and Microstructures Institute of Semiconductors Chinese Academy of Sciences Beijing 100083 China NOVITAS Nanoelectronics Centre of Excellence School of Electrical and Electronic Engineering Nanyang Technological University Singapore 639798 Singapore

We review lattice vibrational modes in atomically thin two-dimensional （2D） layered materials, focusing on 2D materials beyond graphene, such as group VI transition metal dichalcogenides, topological insulator bismuth chalcogenides, and black phosphorus. Although the composition and structure of those materials are remarkably different, they share a common and important feature, i.e., their bulk crystals are stacked via van der Waals interactions between ＂layers＂, while each layer is comprised of one or more atomic planes. First, we review the background of some 2D materials （MX2, M = Mo, W; X = S, Se, Te. bi2X3, X = Se, Te. Black phosphorus）, including crystalline structures and stacking order. We then review the studies on vibrational modes of layered materials and nanostructures probed by the powerful yet nondestructive Raman spectroscopy technique. Based on studies conducted before 2010, recent investigations using more advanced techniques have pushed the studies of phonon modes in 2D layered materials to the atomically thin regime, down to monolayers. We will classify the recently reported general features into the following categories： phonon confinement effects and electron-phonon coupling, anomalous shifts in high-frequency intralayer vibrational modes and surface effects, reduced dimensionality and lower symmetry, the linear chain model and the substrate effect, stacking orders and interlayer shear modes, polarization dependence, and the resonance effect. Within the seven categories, both intralayer and interlayer vibrational modes will be discussed. The comparison between different materials will be provided as well.

关键词： phonon lattice vibration Raman spectroscopy two-dimensional transition metaldichalcogenide black phosphorus

A novel missense variant in ACAA1 contributes to early-onset Alzheimer’s disease,impairs lysosomal function,and facilitates amyloid-p pathology and cognitive decline

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Signal Transduction and Targeted Therapy 2021年第9期6卷 2920-2935页

作者： Rongcan luo yu Fan Jing yang Maosen ye Deng-Feng zhang Kun Guo Xiao Li Rui bi Min Xu lu-Xiu yang yu Li Xiaoqian Ran Hong-yan Jiang Chen zhang Liwen Tan Nengyin Sheng yong-Gang yao Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences&yunnan Province and KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common DiseasesKunming Institute of ZoologyChinese Academy of SciencesKunmingYunnanChina Kunming College of Life Science University of Chinese Academy of SciencesKunmingYunnanChina State Key Laboratory of Genetic Resources and Evolution Kunming Institute of ZoologyChinese Academy of SciencesKunmingChina Department of Psychiatry The First Affiliated Hospital of Kunming Medical UniversityKunmingChina Division of Mood Disorders Shanghai Mental Health CenterShanghai Jiao Tong University School of MedicineShanghaiChina Mental Health Institute of the Second Xiangya Hospital Central South UniverstyChangshaChina Center for Excellence in Animal Evolution and Genetics Chinese Academy of SciencesKunmingYunnanChina CAS Center for Excellence in Brain Science and Intelligence Technology Chinese Academy of SciencesShanghaiChina

Alzheimer’s disease(AD)is characterized by progressive synaptic dysfunction,neuronal death,and brain atrophy,with amyloid-p(Ap)plaque deposits and hyperphosphorylated tau neurofibrillary tangle accumulation in the brain tissue,which all lead to loss of cognitive *** mutations in the well-known AD causal genes including APP,PSEN1,and PSEN2 impair a variety of pathways,including protein processing,axonal transport,and metabolic *** we identified a missense variant rs117916664(c.896T>C,***299Ser[p.N299S])of the acetyl-CoA acyltransferase 1(ACM1)gene in a Han Chinese AD family by whole-genome sequencing and validated its association with early-onset familial AD in an independent *** in vitro and in vivo evidence showed that ACAA1 p.N299S contributes to AD by disturbing its enzymatic activity,impairing lysosomal function,and aggravating the Ap pathology and neuronal loss,which finally caused cognitive impairment in a murine *** findings reveal a fundamental role of peroxisome-mediated lysosomal dysfunction in AD pathogenesis.

关键词： Alzheimer amyloid lysosomal

Geometrical reconstruction of fluorescence events observed by the LHAASO experiment

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Chinese Physics C 2021年第4期45卷 416-425页

作者： F.Aharonian Q.An Axikegu L.X.Bai y.X.Bai y.W.Bao D.Bastieri X.J.bi y.J.bi H.Cai J.T.Cai z.Cao z.Cao J.Chang J.F.Chang X.C.Chang B.M.Chen J.Chen L.Chen L.Chen L.Chen M.J.Chen M.L.Chen Q.H.Chen S.H.Chen S.z.Chen T.L.Chen X.L.Chen y.Chen N.Cheng y.D.Cheng S.W.Cui X.H.Cui y.D.Cui B.z.Dai H.L.Dai z.G.Dai Danzengluobu D.della Volpe B.DEtorre Piazzoli X.J.Dong J.H.Fan y.z.Fan z.X.Fan J.Fang J.Fang C.F.Feng L.Feng S.H.Feng y.L.Feng B.Gao C.D.Gao Q.Gao W.Gao M.M.Ge L.S.Geng G.H.Gong Q.B.Gou M.H.Gu J.G.Guo X.L.Guo y.Q.Guo y.y.Guo y.A.Han H.H.He H.N.He J.C.He S.L.He X.B.He y.He M.Heller y.K.Hor C.Hou X.Hou H.B.Hu S.Hu S.C.Hu X.J.Hu D.H.Huang Q.L.Huang W.H.Huang X.T.Huang z.C.Huang F.Ji X.L.Ji H.y.Jia K.Jiang z.J.Jiang C.Jin D.Kuleshov K.Levochkin B.B.Li C.Li C.Li F.Li H.B.Li H.C.Li H.y.Li J.Li K.Li W.L.Li X.Li X.Li X.R.Li y.Li y.z.Li z.Li z.Li E.W.Liang y.F.Liang S.J.Lin B.Liu C.Liu D.Liu H.Liu H.D.Liu J.Liu J.L.Liu J.L.Liu J.S.Liu J.y.Liu M.y.Liu R.y.Liu S.M.Liu W.Liu y.N.Liu z.X.Liu W.J.Long R.lu H.K.Lv B.Q.Ma L.L.Ma X.H.Ma J.R.Mao A.Masood W.Mitthumsiri T.Montaruli y.C.Nan B.y..Pang P.Pattarakijwanich z.y.Pei M.y.Qi D.Ruffolo V.Rulev A.Saiz L.Shao O.Shchegolev X.D.Sheng J.R.Shi H.C.Song yu.V.Stenkin V.Stepanov Q.N.Sun X.N.Sun z.B.Sun P.H.T.Tam z.B.Tang W.W.Tian B.D.Wang C.Wang H.Wang H.G.Wang J.C.Wang J.S.Wang L.P.Wang L.y.Wang R.N.Wang W.Wang W.Wang X.G.Wang X.J.Wang X.y.Wang y.D.Wang y.J.Wang y.P.Wang z.Wang z.Wang z.H.Wang z.X.Wang D.M.Wei J.J.Wei y.J.Wei T.Wen C.y.Wu H.R.Wu S.Wu W.X.Wu X.F.Wu S.Q.Xi J.Xia J.J.Xia G.M.Xiang G.Xiao H.B.Xiao G.G.Xin y.L.Xin y.Xing D.L.Xu R.X.Xu L.Xue D.H.yan C.W.yang F.F.yang J.y.yang L.L.yang M.J.yang R.z.yang S.B.yang y.H.yao z.G.yao y.M.ye L.Q.yin N.yin X.H.you z.y.you y.H.yu Q.yuan H.D.zeng T.X.zeng W.zeng z.K.zeng M.zha X.X.zhai B.B.zhang H.M.zhang H.y.zhang J.L.zhang J.W.zhang L.zhang L.zhang L.X.zhang P.F.zhang P.F.zhang R.zhang S.R.zhang S.S.zhang X.zhang X.P.zhang y.zhang y.zhang y.F.zhang y.L.zhang B.zhao J.zhao L.zhao L.z.zhao S.P.zhao F.zheng y.zheng B.zhou H.zhou J.N.zhou P Key Laboratory of Particle Astrophyics&Experimental Physics Division&Computing Center Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Beijing 100049China TIANFU Cosmic Ray Research Center ChengduSichuanChina State Key Laboratory of Paricle Detection and Electronics China University of Science and Technology of China HefeiAnhui 230026China Department of engineering Physics Tsinghua UniversityBeijing 100084China National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China National Space Science Center Chinese Academy of SciencesBeijing 100190China School of Physics Peking UniversityBeijing 100871China Center for Astrophysics Guangzhou UniversityGuangzhouGuangdong 510006China School of Physics and Astronomy&School of Physics(Guangzhou) Sun Yat-sen UniversityZhuhaiGuangdong 519000China School of Physical Science and Technology Guangxi UniversityNanningGuangxi 530004China Hebei Normal University ShijiazhuangHebei 050024China School of Physics and Microelectronics Zhengzhou UniversityZhengzhouHenan 450001China School of Astronomy and Space Science Nanjing UniversityNanjingJiangsu 210023China Key Laboratory of Dark Matter and Space Astronomy Purple Mountain ObservatoryChinese Academy of SciencesNanjingJiangsu 210023China Institute of Frontier and Interdisciplinary Science Shandong UniversityQingdaoShandong 266237China Key Laboratory for Research in Galaxies and Cosmology Shanghai Astronomical ObservatoryChinese Academy of SciencesShanghai 200030China Tsung-Dao Lee Institute&School of Physics and Astronomy Shanghai Jiao Tong UniversityShanghai 200240China School of Physical Science and Technology Southwest Jiaotong UniversityChengduSichuan 610031China College of Physics Sichuan UniversityChengduSichuan 610065China Key Laboratory of Cosmic Rays(Tibet University) Ministry of EducationLhasaTibet 850000China School of physics and technology Wuhan UniversityWuhanHubei 430072Ch

The LHAASO-WFCTA experiment,which aims to observe cosmic rays in the sub-EeV range using the fluorescence technique,uses a new generation of high-performance *** ensure that the experiment has ex-cellent detection capability associated with the measurement of the energy spectrum,the primary composition of cosmic rays,and so on,an accurate geometrical reconstruction of air-shower events is *** paper de-scribes the development and testing of geometrical reconstruction for stereo viewed events using the WFCTA(Wide Field of view Cherenkov/Fluorescence Telescope Array)*** approaches,which take full advantage ofthe WFCTA *** *** is the stereo-angular method,which uses the pointing of triggered SiPMs in the shower trajectory,and the other is the stereo-timing method,which uses the triggering time of the fired *** results show that both methods have good geometrical resolution:the resolution of the stereo-timing method is slightly better than the stereo-angular method because the resolution of the latter is slightly limited by the shower track length.

关键词： cosmic ray fluorescence telescope stereo observation geometrical reconstruction

CEPC Technical Design Report

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Radiation Detection Technology and Methods 2024年第1期8卷 I0003-I0016,1-1091页

作者： Waleed Abdallah Tiago Carlos Adorno de Freitas Konstantin Afanaciev Shakeel Ahmad Ijaz Ahmed Xiaocong Ai Abid Aleem Wolfgang Altmannshofer Fabio Alves Weiming An Rui An Daniele Paolo Anderle Stefan Antusch yasuo Arai Andrej Arbuzov Abdesslam Arhrib Mustafa Ashry Sha Bai yu Bai yang Bai Vipul Bairathi Csaba Balazs Philip Bambade yong Ban Tripamo Bandyopadhyay Shou-Shan Bao Desmond P.Barber Ayse Bat Varvara Batozskaya Subash Chandra Behera Alexander Belyaev Michele Bertucci Xiao-Jun bi yuanjie bi Tianjian bian Fabrizio bianchi Thomas biekotter Michela biglietti Shalva bilanishvili Deng binglin Denis Bodrov Anton Bogomyagkov Serge Bondarenko Stewart Boogert Maarten Boonekamp Marcello Borri Angelo Bosotti Vincent Boudry Mohammed Boukidi Igor Boyko Ivanka Bozovic Giuseppe Bozzi Jean-Claude Brient Anastasiia Budzinskaya Masroor Bukhari Vladimir Bytev Giacomo Cacciapaglia Hua Cai Wenyong Cai Wujun Cai yijian Cai yizhou Cai yuchen Cai Haiying Cai Huacheng Cai Lorenzo Calibbi Junsong Cang Guofu Cao Jianshe Cao Antoine Chance Xuejun Chang yue Chang zhe Chang Xinyuan Chang Wei Chao Auttakit Chatrabhuti yimin Che yuzhi Che bin Chen Danping Chen Fuqing Chen Fusan Chen Gang Chen Guoming Chen Hua-Xing Chen Huirun Chen Jinhui Chen Ji-yuan Chen Kai Chen Mali Chen Mingjun Chen Mingshui Chen Ning Chen Shanhong Chen Shanzhen Chen Shao-Long Chen Shaomin Chen Shiqiang Chen Tianlu Chen Wei Chen Xiang Chen Xiaoyu Chen Xin Chen Xun Chen Xurong Chen ye Chen ying Chen yukai Chen zelin Chen zilin Chen Gang Chen Boping Chen Chunhui Chen Hok Chuen Cheng Huajie Cheng Shan Cheng Tongguang Cheng yunlong Chi Pietro Chimenti Wen Han Chiu Guk Cho Ming-Chung Chu Xiaotong Chu ziliang Chu Guglielmo Coloretti Andreas Crivellin Hanhua Cui Xiaohao Cui zhaoyuan Cui Brunella D'Anzi Ling-yun Dai Xinchen Dai Xuwen Dai Antonio De Maria Nicola De Filippis Christophe De La Taille Francesca De Mori Chiara De Sio Elisa Del Core Shuangxue Deng Wei-Tian Deng zhi Deng ziyan Deng Bhupal Dev Tang Dewen biagio Di Micco Ran Ding Siqin Dingl yadong Ding Haiyi Dong Jianin AGH University of Science and Technology Faculty of Physics and Applied Computer ScienceKrakow Anhui University HefeiAnhui Applied Physics Department Federal Urdu University of ArtsScience and TechnologyIslamabad Banaras Hindu University Institute of ScienceVaranasi Bandirma Onyedi Eylul University Bandirma Beihang University Beijing Beijing Computational Science Research Center Beijing Beijing Conveyi LTD Beijing Beijing Glass Research Institute Co. LtdBeijing Beijing Institute of Technology Beijing Beijing Normal University Beijing Brown University ProvidenceRI Budker Institute of Nuclear Physics Novosibirsk Cadi Ayyad University Laboratory of Fundamental and Applied PhysicsPolydisciplinary FacultyMarrakech Cairo University Giza Center for Theory and Computation National Tsing Hua UniversityHsinchu Central China Normal University WuhanHubei Central South University ChangshaHunan Centro de Fisica Teorica de Particulas Universidade Tecnica de LisboaLisboa Chengdu KaitengSifang Digital Radio&TV Equipment Co. LtdChengduSichuan China academy of engineering physics MianyangSichuan China building materials academy Beijing China Center of Advanced Science and Technology Beijing China Institute of Atomic Energy Beijing China Jiliang University HangzhouZhejiang China Nuclear Instrument CO. LTDBeijing China University of Geosciences Beijing China University of Geosciences WuhanHubei China University of Mining and Technology XuzhouJiangsu China West Normal University NanchongSichuan Chongqing University Department of PhysicsChongqing Chulalongkorn University Bangkok City University of Hong Kong Department of PhysicsHong Kong Cockcroft Institute Daresbury Cornell University IthacaNY CPPM(AMU/IPhU&CNRS/INP) Marseille Dalian Minzu University DalianLiaoning Dalian University of Technology Department of PhysicsDalian Deutsches Elektronen-Synchrotron DESy Hamburg Dzhelepov Laboratory of Nuclear Problems of Joint Institute for Nuclear Research(DLNP JINR) Dubna East China University Of Science And Technol

The Circular Electron Positron Collider(CEPC)is a large scientific project initiated and hosted by China,fostered through extensive collaboration with international *** complex comprises four accelerators:a 30 GeV Linac,a 1.1 GeV Damping Ring,a Booster capable of achieving energies up to 180 GeV,and a Collider operating at varying energy modes(z,W,H,and tt).The Linac and Damping Ring are situated on the surface,while the subterranean Booster and Collider are housed in a 100 km circumference underground tunnel,strategically accommodating future expansion with provisions for a potential Super Proton Proton Collider(SPPC).The CEPC primarily serves as a Higgs *** its baseline design with synchrotron radiation(SR)power of 30 MW per beam,it can achieve a luminosity of 5×10^(34)cm^(-2)s^(-1)per interaction point(IP),resulting in an integrated luminosity of 13 ab^(-1)for two IPs over a decade,producing 2.6 million Higgs *** the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons,facilitating precise measurements of Higgs coupling at sub-percent levels,exceeding the precision expected from the HL-LHC by an order of *** Technical Design Report(TDR)follows the Preliminary Conceptual Design Report(Pre-CDR,2015)and the Conceptual Design Report(CDR,2018),comprehensively detailing the machine's layout,performance metrics,physical design and analysis,technical systems design,R&D and prototyping efforts,and associated civil engineering ***,it includes a cost estimate and a preliminary construction timeline,establishing a framework for forthcoming engineering design phase and site selection *** is anticipated to begin around 2027-2028,pending government approval,with an estimated duration of 8 *** commencement of experiments and data collection could potentially be initiated in the mid-2030s.

关键词： initiated exceeding precise

Observation of the Crab Nebula with LHAASO-KM2A−a performance study

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Chinese Physics C 2021年第2期45卷 518-530页

作者： F.Aharonian Q.An Axikegu L.X.Bai y.X.Bai y.W.Bao D.Bastieri X.J.bi y.J.bi H.Cai J.T.Cai z.Cao J.Chang J.F.Chang X.C.Chang B.M.Chen J.Chen L.Chen M.J.Chen M.L.Chen Q.H.Chen S.H.Chen S.z.Chen T.L.Chen X.L.Chen y.Chen N.Cheng y.D.Cheng S.W.Cui X.H.Cui y.D.Cui B.z.Dai H.L.Dai z.G.Dai D.della Volpe B.D'Ettorre Piazzoli X.J.Dong J.H.Fan y.z.Fan z.X.Fan J.Fang K.Fang C.F.Feng L.Feng S.H.Feng y.L.Feng B.Gao C.D.Gao Q.Gao W.Gao M.M.Ge L.S.Geng G.H.Gong Q.B.Gou M.H.Gu J.G.Guo X.L.Guo y.Q.Guo y.y.Guo y.A.Han H.H.He H.N.He J.C.He S.L.He X.B.He y.He M.Heller y.K.Hor C.Hou X.Hou H.B.Hu S.Hu S.C.Hu X.J.Hu D.H.Huang Q.L.Huang W.H.Huang X.T.Huang z.C.Huang F.Ji X.L.Ji H.y.Jia K.Jiang z.J.Jiang C.Jin D.Kuleshov K.Levochkin B.B.Li C.Li F.Li H.B.Li H.C.Li H.y.Li J.Li K.Li W.L.Li X.Li X.R.Li y.Li y.z.Li z.Li E.W.Liang y.F.Liang S.J.Lin B.Liu C.Liu D.Liu H.Liu H.D.Liu J.Liu J.L.Liu J.S.Liu J.y.Liu M.y.Liu R.y.Liu S.M.Liu W.Liu y.N.Liu z.X.Liu W.J.Long R.lu H.K.Lv B.Q.Ma L.L.Ma X.H.Ma J.R.Mao A.Masood W.Mitthumsiri T.Montaruli y.C.Nan B.y.Pang P.Pattarakijwanich z.y.Pei M.y.Qi D.Ruffolo V.Rulev A.Sáiz L.Shao O.Shchegolev X.D.Sheng J.R.Shi H.C.Song yu.V.Stenkin V.Stepanov Q.N.Sun X.N.Sun z.B.Sun P.H.T.Tam z.B.Tang W.W.Tian B.D.Wang C.Wang H.Wang H.G.Wang J.C.Wang J.S.Wang L.P.Wang L.y.Wang R.N.Wang W.Wang X.G.Wang X.J.Wang X.y.Wang y.D.Wang y.J.Wang y.P.Wang z.Wang z.H.Wang z.X.Wang D.M.Wei J.J.Wei y.J.Wei T.Wen C.y.Wu H.R.Wu S.Wu W.X.Wu X.F.Wu S.Q.Xi J.Xia J.J.Xia G.M.Xiang G.Xiao H.B.Xiao G.G.Xin y.L.Xin y.Xing D.L.Xu R.X.Xu L.Xue D.H.yan C.W.yang F.F.yang J.y.yang L.L.yang M.J.yang R.z.yang S.B.yang y.H.yao z.G.yao y.M.ye L.Q.yin N.yin X.H.you z.y.you y.H.yu Q.yuan H.D.zeng T.X.zeng W.zeng z.K.zeng M.zha X.X.zhai B.B.zhang H.M.zhang H.y.zhang J.L.zhang J.W.zhang L.zhang L.X.zhang P.F.zhang P.P.zhang R.zhang S.R.zhang S.S.zhang X.zhang X.P.zhang y.zhang y.F.zhang y.L.zhang B.zhao J.zhao L.zhao L.z.zhao S.P.zhao F.zheng y.zheng B.zhou H.zhou J.N.zhou P.zhou R.zhou X.X.zhou C.G.zhu F.R.zhu H.zhu K.J.zhu X.zuo Key Laboratory of Particle Astrophyics&Experimental Physics Division&Computing Center Institute of High Energy PhysicsChinese Academy of Sciences100049 BeijingChina University of Chinese Academy of Sciences 100049 BeijingChina TIANFU Cosmic Ray Research Center ChengduSichuanChina State Key Laboratory of Particle Detection and Electronics China University of Science and Technology of China 230026 HefeiAnhuiChina Department of engineering Physics Tsinghua University100084 BeijingChina National Astronomical Observatories Chinese Academy of Sciences100101 BeijingChina National Space Science Center Chinese Academy of Sciences100190 BeijingChina School of Physics Peking University100871 BeijingChina Center for Astrophysics Guangzhou University510006 GuangzhouGuangdongChina School of Physics and Astronomy&School of Physics(Guangzhou) Sun Yat-sen University519000 ZhuhaiGuangdongChina School of Physical Science and Technology Guangxi University530004 NanningGuangxiChina Hebei Normal University 050024 ShijiazhuangHebeiChina School of Physics and Microelectronics Zhengzhou University450001 ZhengzhouHenanChina School of Astronomy and Space Science Nanjing University210023 NanjingJiangsuChina Key Laboratory of Dark Matter and Space Astronomy Purple Mountain ObservatoryChinese Academy of Sciences210023 NanjingJiangsuChina Institute of Frontier and Interdisciplinary Science Shandong University266237 QingdaoShandongChina Key Laboratory for Research in Galaxies and Cosmology Shanghai Astronomical ObservatoryChinese Academy of Sciences200030 ShanghaiChina Tsung-Dao Lee Institute&School of Physics and Astronomy Shanghai Jiao Tong University200240 ShanghaiChina School of Physical Science and Technology&School of Information Science and Technology Southwest Jiaotong University610031 ChengduSichuanChina College of Physics Sichuan University610065 ChengduSichuanChina Key Laboratory of Cosmic Rays(Tibet University) Ministry of Education850000 LhasaTibetChina School of Physics and Tec

A sub-array of the Large High Altitude Air Shower Observatory(LHAASO),KM2A is mainly designed to observe a large fraction of the northern sky to hunt for γ-ray sources at energies above 10 *** though the detector construction is still underway,half of the KM2A array has been operating stably since the end of *** this paper,we present the KM2A data analysis pipeline and the first observation of the Crab Nebula,a standard candle in very high energy γ-ray *** detect γ-ray signals from the Crab Nebula in both energy ranges of 10-100 TeV and>100 TeV with high significance,by analyzing the KM2A data of 136 live days between December 2019 and May *** the observations,we test the detector performance,including angular resolution,pointing accuracy and cosmic-ray background rejection *** energy spectrum of the Crab Nebula in the energy range 10-250 TeV fits well with a single power-law function dN/dE=(1.13±0.05stat±0.08sys)×10^(-14).(E/20 TeV)-309±0.06stat±0.02syscm^(-2) s^(-1) TeV^(-1).It is consistent with previous measurements by other *** opens a new window of γ-ray astronomy above 0.1 PeV through which new ultrahigh-energy γ-ray phenomena,such as cosmic PeVatrons,might be discovered.

关键词： γ-ray Crab Nebula extensive air showers cosmic rays

马铃薯ARM基因家族的全基因组鉴定及表达分析

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作物学报 2024年第6期50卷 1451-1466页

作者：刘震陈丽敏李志涛朱金勇王玮璐齐喆颖姚攀锋毕真真孙超白江平刘玉汇甘肃农业大学省部共建干旱生境作物学国家重点实验室甘肃兰州730070 甘肃农业大学农学院甘肃兰州730070 甘肃省教育厅甘肃兰州730030

ARM蛋白重复序列(Armadillo repeats)广泛存在于高等植物中,它们参与多种细胞过程,如信号转导、核转运以及对多种生物/非生物胁迫的响应。本研究在马铃薯(Solanum tuberosum L.)全基因组水平下鉴定出了54个马铃薯ARM基因家族成员(StARM... 详细信息

ARM蛋白重复序列(Armadillo repeats)广泛存在于高等植物中,它们参与多种细胞过程,如信号转导、核转运以及对多种生物/非生物胁迫的响应。本研究在马铃薯(Solanum tuberosum L.)全基因组水平下鉴定出了54个马铃薯ARM基因家族成员(StARMs),它们不均匀的分布在12条染色体上。根据其蛋白结构和系统发育特征,将54个StARMs分为3个亚家族。片段重复事件在马铃薯ARM基因家族的扩展中起主要作用。共线性分析发现,StARMs与番茄(Solanum lycopersicum)、拟南芥(Arabidopsis)、甘蓝(Brassica oleracea)、水稻(Oryza sativa)、玉米(zea mays)分别有51对、17对、25对、6对和10对直系同源基因,这些基因均在纯化选择下进化。RNA-seq数据分析发现,4个StARM基因在匍匐茎中特异表达,2个StARM基因在根和心皮中特异表达,1个StARM基因在块茎中特异表,还有一些StARM基因参与了马铃薯对生物/非生物胁迫的响应。此外,本研究对3个不同颜色马铃薯块茎组织(薯皮和薯肉)进行了RNA-seq测序,分析了54个StARMs在不同颜色马铃薯块茎组织中的表达模式,并利用qPCR分析了StARMs在3个不同颜色块茎杂交子代薯肉中的相对表达量,筛选出了4个可能参与马铃薯块茎花色素苷生物合成的候选基因。本研究为进一步了解StARM基因家族的特征,深入分析StARM基因在马铃薯抵御生物/非生物胁迫和调控块茎花色素苷生物合成中的功能提供了理论依据。

关键词：马铃薯 ARM基因家族生物/非生物胁迫花色素苷生物合成表达分析