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Poor agreement between endoscopists and gastrointestinal pathologists for the interpretation of probe-based confocal laser endomicroscopy findings

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World Journal of Gastroenterology 2014年第47期20卷 17993-18000页

作者： Shajan Peter Leona Council ji young bang Helmut Neumann Klaus Mnkemüller Shyam Varadarajulu Charles Melbern Wilcox Division of Gastroenterology and Hepatology University of AlabamaBirminghamAL 35294-0012United States Department of Pathology University of Alabama at BirminghamBirminghamAL 35294-0012United States Department of Medicine 1 University of Erlangen-Nuremberg91054 ErlangenGermany

AIM: To compare the interpretation of probe-based confocal laser endomicroscopy (pCLE) findings between endoscopists and gastrointestinal (GI)-pathologists.

关键词： Confocal endomicroscopy Gastointestinal Interobserver variation

Feasibility Study of R134a/R404a Cascade Heat Pump Cycle in Heat Pump Dryers with Electrical Heaters at Low Temperatures

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Journal of Thermal Science 2015年第5期24卷 463-467页

作者： ji Woo Jeong young Lim Lee Dept. of Mechanical Engineering Kongju National University Dept. of Mechanical and Automotive Engineering Kongju National University

Heat pump cycles have been widely applied to dryers for their high efficiency. However, low–efficiency electrical heaters are often used during early drying stage for frozen foods or winter since a standard heat pump cycle cannot operate at low temperature. This study introduced cascade heat pumps replacing electrical heaters to improve dryer performance at low temperatures. Experiments were performed to examine changes in performance of the cascade heat pump dryers in relation to ambient temperature, low-stage cycle mass flow rate, and high-stage cycle mass flow rate. The results showed a significant improvement in low-temperature dryer performance with the introduction of cascade heat pump cycles.

关键词： Cascade cycle R134a/R404a Heat pump dryer COP Energy efficiency

Healthy, natural, efficient and tunable lighting: four-package white LEDs for optimizing the circadian effect, color quality and vision performance

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Light(Science & Applications) 2014年第1期3卷 314-322页

作者： ji Hye Oh Su ji Yang young Rag Do Department of Chemistry Kookmin UniversitySeoul 136-702Korea

To date,most current reports on the development and optimization of artificial lighting sources have focused on the energy performance levels and limited color qualities of white light-emitting diodes(LEDs).However,these properties are insufficient in terms of representing all performance levels required when adjusting white LEDs for healthy and smart ***,we introduce essential and advanced figures of merit pertaining to circadian performance as well as vision performance and color *** compare all possible properties of commercialized artificial lighting,daylight and four-package white LEDs which consist of long-wavelength pass dichroic filter(LPDF)-capped,phosphor-converted red,amber and green LEDs(pc-LEDs)and a blue *** show that these tunable four-package white LEDs produce a tunable circadian effect for melatonin suppression/secretion,a high color quality for color perception/reproduction,high efficiency for energy savings and tunable figures of merit for the smart LED lighting market.

关键词： circadian effect color quality solid-state lighting vision performance white LED

Intravenous iron supplementation may be superior to observation in acute isovolemic anemia after gastrectomy for cancer

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World Journal of Gastroenterology 2014年第7期20卷 1852-1857页

作者： Hong Man Yoon young-Woo Kim Byung Ho Nam Daniel Reim bang Wool Eom ji Yeon Park Keun Won Ryu Gastric Cancer Branch Research Institute and HospitalNational Cancer CenterGoyangsi 410-769South Korea Cancer Registration and Biostatistics Branch and Center for Clinical Trials National Cancer CenterGoyang-si 410-769South Korea Department of Surgery Soon Chun Hyang University HospitalSeoul 140-743South Kore

AIM: To determine whether the application of post-operative intravenous (IV)-iron for acute isovolemic anemia after gastrectomy for cancer may be effective.

关键词： Intravenous iron Observation Gastric cancer Acute isovolemic anemia Gastrectomy

Safety of endoscopic ultrasound-guided ethanol ablation for pancreatic cystic lesions: A single-center experience of 214 patients

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Hepatobiliary & Pancreatic Diseases International 2019年第6期18卷 562-568页

作者： jin Ho Choi Sang Hyub Lee young Hoon Choi Min Su You bang-Sup Shin Woo Hyun Paik ji Kon Ryu Yong-Tae Kim Department of Internal Medicine Liver Research Institute Seoul National University College of Medicine

Background:Endoscopic ultrasound-guided ethanol ablation(EUS-EA)for pancreatic cystic lesions(PCLs)has been used in recent years as a feasible treatment modality for low malignant probability PCLs or patients considered high-risk for *** present study aimed to confirm the safety of EUS-EA and to find predictive factors for adverse event(AE).Methods:A retrospective review was performed from the prospectively maintained database of patients who underwent EUS-EA for PCLs from June 2006 to April 2018 at Seoul National University *** primary outcomes of the study were the rates of AEs and severe AEs by *** secondary outcome was the predictive factors of AEs including acute pancreatitis and abdominal ***:A total of 214 patients were evaluated and the diagnoses of PCLs according to cystic fluid analysis and clinical features were as follows:serous cystic neoplasm(32.2%),mucinous cystic neoplasm(26.6%),branch duct type intraductal papillary mucinous neoplasm(BD-IPMN)(29.4%),and pseudocyst(11.7%).Three patients(1.4%)experienced severe ***,AEs occurred in 71(33.2%)***-IPMN(OR:2.87;95%CI:1.05–7.84;P=0.040),multilocular cysts(OR:3.59;95%CI:1.09–11.85;P=0.036),suspected ethanol leakage during procedure(OR:10.68;95%CI:1.98–57.53;P=0.006),and sticky cystic fluid(OR:3.83;95%CI:1.20–12.24;P=0.024)were predictive factors for post-procedural acute *** of uncinate process(OR:2.99;95%CI:1.22–7.35;P=0.017)and PCLs with exophytic portion(OR:3.70;95%CI:1.96–7.01;P<0.001)were predictive factors for post-procedural abdominal ***:EUS-EA is a safe procedure with a very low rate of severe *** seems possible to predict the AEs according to the features of the procedure and PCLs.

关键词： Pancreatic cyst EUS-guided ethanol ablation Adverse events

Endoscopic band ligation: Beyond prevention and management of gastroesophageal varices

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World Journal of Gastroenterology 2013年第27期19卷 4271-4276页

作者： Jeong-Seon ji young-Seok Cho Division of Gastroenterology Department of Internal MedicineIncheon St. Mary's HospitalThe Catholic University of Korea College of Medicine Division of Gastroenterology Department of Internal MedicineUijeongbu St. HospitalThe Catholic University of Korea College of Medicine

Endoscopic band ligation (EBL) is the preferred endoscopic technique for the endoscopic treatment of acute esophageal variceal bleeding. EBL has also been used to treat nonvariceal bleeding. Recently, Han et al demonstrated that EBL can be a feasible and safe alternate technique for the management of iatrogenic gastric perforation especially in cases in which closure with endoclips is difficult. EBL is technically simpler to perform than other methods and provides a good view of the lesions under direct pressure and suction from the transparent ligation cap. EBL can be used even if the diameter of the perforation is greater than 10 mm or if there is a severe tangential angle. In this commentary, we discuss the efficacy and safety of EBL for the closure of iatrogenic gastrointestinal perforation. We also discuss the advantages and disadvantages of EBL for the treatment of nonvariceal bleeding.

关键词： Band ligation Endoscopy Intestinal perforation Gastrointestinal hemorrhage

The diluted atropine for inhibition of myopia progression in Korean children

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International Journal of Ophthalmology(English edition) 2018年第10期11卷 1657-1662页

作者： ji-Sun Moon Sun young Shin Department of Ophthalmology National Medical Center Department of Ophthalmology and Visual Science Seoul St.Mary's Hospital College of Medicine the Catholic University of Korea

AIM：To evaluate the efficacy and safety of three different concentrations of diluted atropine for the control of myopia in Korean children,and to assess the risk factors associated with rapid myopia ***：A total of 285 children,with refractive errors within the range of-6 diopters（D）between 5 and 14 years of age were *** using 0.01%,or 0.025%,or 0.05% atropine,for about 1y,changes in refraction,axial lengths and frequency of adverse events were *** regression analyses were performed to evaluate the risk factors associated with rapid myopia ***：The changes in the mean spherical equivalent values were -0.134 D/mo in the before atropine group,-0.070 D/mo in the 0.01% atropine group,-0.047 D/mo in the 0.025% atropine group,and -0.019 D/mo in the 0.05% atropine group,with significant differences between the groups（P〈0.001）.The axial elongation was 0.046 mm/mo,0.037 mm/mo,0.025 mm/mo,and 0.019 mm/mo respectively,with significant differences between the groups（P=0.003）.The incidence of photophobia and near vision difficulty was not different among the three atropine groups（P=0.425and P=0.356,respectively）.Multivariate logistic regression analyses showed that only highly myopic parents were a significant predictive factor of rapid myopia progression in Korean children（odds ratio,8.155;95% confidence interval,3.626-18.342;P〈0.001）.CONCLUSION：Treatment with 0.01%,0.025% and 0.05% atropine solution inhibits myopia progression in Korean children in a dose-dependent *** with highly myopic parents preferentially shows a rapid myopia progression rate.

关键词： atropine Korean children myopia progression

Diagnostic evaluation of endoscopic ultrasonography with submucosal saline injection for differentiating between T1a and T1b early gastric cancer

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World Journal of Gastroenterology 2022年第46期28卷 6564-6572页

作者： ji young Park Tae Joo Jeon Department of Internal Medicine Inje University College of MedicineSanggye Paik HospitalSeoul 01757South Korea Department of Internal Medicine Yonsei University College of MedicineSeoul 03722South Korea

BACKGROUND Endoscopic ultrasonography(EUS)has become a reliable method for predicting the invasion depth of early gastric cancer(EGC).However,diagnostic accuracy of EUS is affected by several *** particular,it is difficult to differentiate between T1a and T1b EGC through *** To confirm whether submucosal saline injection(SSI)could improve the accuracy of EUS in distinguishing T1a and T1b lesions in *** Twenty-four patients with EGC were examined by EUS and subsequently by SSI combined EUS to compare the degree of tumor ***,they underwent endoscopic or surgical resection within 7 *** diagnostic accuracy of EUS and SSI combined EUS was evaluated based on the final pathological findings *** injected into the submucosa acted as an echoic contrast enhancing agent and had the effect of distinguishing the mucosal and submucosal layers *** Of total 24 patients,23 were diagnosed with EGC(T1 cancer:13 as T1a,and 10 as T1b).Standard EUS identified 6 of 13 T1a cancer patients and 3 of 10 T1b cancer ***,EUS-SSI identified 12 of 13 T1a cancer patients and 6 of 10 T1b cancer *** this study,SSI combined EUS was more accurate than EUS alone in diagnosing T1a and T1b lesions of EGC(75.0%and 37.5%,respectively).CONCLUSION SSI improved the diagnostic accuracy of EUS in distinguishing between the T1a and T1b stages in EGC.

关键词： Endoscopic ultrasonography Gastric cancer Endoscopy Surgery

Clinical significance of the neutrophil-lymphocyte ratio as an early predictive marker for adverse outcomes in patients with acute pancreatitis

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World Journal of Gastroenterology 2017年第21期23卷 3883-3889页

作者： Tae Joo Jeon ji young Park Division of Gastroenterology Department of Internal Medicine Inje University College of Medicine Sanggye Paik Hospital

AIM To investigated the prognostic value of the neutrophillymphocyte ratio(NLR) in patients with acute pancreatitis and determined an optimal cut-off value for the prediction of adverse outcomes in these *** We retrospectively analyzed 490 patients with acute pancreatitis diagnosed between March 2007 and December 2012. NLRs were calculated at admission and 24, 48, and 72 h after admission. Patients were grouped according to acute pancreatitis severity and organ failure occurrence, and a comparative analysis was performed to compare the NLR between groups. RESULTS Among the 490 patients, 70 had severe acute pancreatitis with 31 experiencing organ failure. The severe acute pancreatitis group had a significantly higher NLR than the mild acute pancreatitis group on all 4 d(median, 6.14, 6.71, 5.70, and 4.00 vs 4.74, 4.47, 3.20, and 3.30, respectively, P < 0.05). The organ failure group had a significantly higher NLR than the group without organ failure on all 4 d(median, 7.09, 6.72, 6.27, and 6.24 vs 4.85, 4.49, 3.35, and 2.34, respectively, P < 0.05). The optimal cut-off value for baseline NLR was 4.76 in predicting severity and 4.88in predicting organ failure in acute pancreatitis. CONCLUSION Elevated baseline NLR correlates with severe acute pancreatitis and organ failure.

关键词： Acute pancreatitis Neutrophil-lymphocyte ratio Organ failure Severe acute pancreatitis