检索结果-南通市图书馆

Effects of lobaplatin and oxaliplatin on biological behavior of colorectal carcinoma cell line

在线全文

学校读者我要写书评

暂无评论

The Chinese-German Journal of Clinical Oncology 2010年第1期9卷 36-39页

作者： Xue bai bo yu Junfeng Du Shujun yuan Fuyi Zuo Liang Sun General Surgery Center of PLA General Hospital of Beijing Command Beijing 100700 China

Objective： The aim of the study was to observe the effects of Iobaplatin and oxaliplatin on biological behavior of colorectal carcinoma cell line. Methods： The human colorectal carcinoma cell line LoVo and HR-8348 were used in the present study, and different concentrations of Iobaplatin and oxaliplatin served as inhibitors. The invasion and metastasis potential were evaluated with Transwell chamber, and cell inhibition ratio was measured with MTT assay. Results： Lobaplatin and oxaliplatin could significantly decrease the abilities of invasion and metastasis of LoVo and HR-8348 as compared with the control group （P 〈 0.01）, but no difference between Iobaplatin and oxaliplatin groups was observed （P 〉 0.05）. No difference was found in the cell inhibition ratio between the Iobaplatin and oxaliplatin groups （P 〉 0.05）. Lobaplatin could inhibit colorectal carcinoma cells that oxaliplatin couldn＇t do. Conclusion： Lobaplatin is a new antitumor platinum drug and can inhibit colorectal carcinoma cells. Moreover, Iobaplatin could also inhibit colorectal carcinoma cells which are resistant to oxaliplatin.

关键词： colorectal cancer oxaliplatin Iobaplatin chemotherapy

boosting bidirectional sulfur conversion enabled by introducing boron-doped atoms and phosphorus vacancies in Ni2P for lithium-sulfur batteries

在线全文

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2025年第1期100卷 760-769页

作者： Lin Peng yu bai Hang Li Meixiu Qu Zhenhua Wang Kening Sun Advanced Research Institute of Multidisciplinary Science Beijing Institute of Technology Beijing Key Laboratory of Chemical Power Source and Green Catalysis School of Chemistry and Chemical Engineering Beijing Institute of Technology

Lithium-sulfur （Li-S） batteries have gained great attention due to the high theoretical energy density and low cost,yet their further commercialization has been obstructed by the notorious shuttle effect and sluggish redox ***,we supply a strategy to optimize the electron structure of Ni2P by concurrently introducing B-doped atoms and P vacancies in Ni2P （Vp-B-Ni2P）,thereby enhancing the bidirectional sulfur *** study indicates that the simultaneous introduction of B-doped atoms and P vacancies in Ni2P causes the redistribution of electron around Ni atoms,bringing about the upward shift of d-band center of Ni atoms and effective d-p orbital hybridization between Ni atoms and sulfur species,thus strengthening the chemical anchoring for lithium polysulfides （LiPSs） as well as expediting the bidirectional conversion kinetics of sulfur ***,theoretical calculations reveal that the incorporation of B-doped atoms and P vacancies in Ni2P selectively promotes Li2S dissolution and nucleation ***,the Li-S batteries with Vp-B-Ni2P-separators present outstanding rate ability of 777 m A h g-1at 5 C and high areal capacity of 8.03 mA h cm-2under E/S of 5μL mg-1and sulfur loading of 7.20 mg *** work elucidates that introducing heteroatom and vacancy in metal phosphide collaboratively regulates the electron structure to accelerate bidirectional sulfur conversion.

关键词： Lithium sulfur batteries

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

液压支架千斤顶漏液原因分析及解决措施

煤炭技术 2021年第5期40卷 178-179页

作者：白育波李文婷西安重装铜川煤矿机械有限公司陕西铜川727031

液压支架是综采工作面重要支护设备,可保护井下人员及设备安全,伴随着液压支架往复支护,立柱千斤会出现漏液等问题,以液压支架油缸泄漏研究及解决措施为题目进行研究并提出解决方案,确保液压支架支护性能,保证生产效率。

关键词：液压支架立柱千斤顶液压密封件泄漏

Ideal Bi-Based Hybrid Anode Material for Ultrafast Charging of Sodium-Ion Batteries at Extremely Low Temperatures

在线全文

学校读者我要写书评

暂无评论

NANO-MICRO LETTERS 2025年第1期17卷 1-16页

作者： bai, Jie Jia, Jian Hui Wang, yu Yang, Chun Cheng Jiang, Qing Jilin Univ Key Lab Automobile Mat Sch Mat Sci & Engn Minist Educ Changchun 130022 Peoples R China

Metallic nanoparticles with excellent size controllability and high loading rate are obtained via ultrafast high temperature shock *** Bi/CNRs-15 electrode exhibits an unprecedented rate performance (237.9 mAh g-1 at 2 A g-1) at - 60 degrees C, while the energy density of the full cell can reach to 181.9 Wh kg-1 at - 40 degrees C.A novel strategy of high-rate activation is proposed to obtain high capacity and superior stability at low temperature by creating new active sites for interfacial reaction. Sodium-ion batteries have emerged as competitive substitutes for low-temperature applications due to severe capacity loss and safety concerns of lithium-ion batteries at - 20 degrees C or lower. However, the key capability of ultrafast charging at ultralow temperature for SIBs is rarely reported. Herein, a hybrid of Bi nanoparticles embedded in carbon nanorods is demonstrated as an ideal material to address this issue, which is synthesized via a high temperature shock method. Such a hybrid shows an unprecedented rate performance (237.9 mAh g-1 at 2 A g-1) at - 60 degrees C, outperforming all reported SIB anode materials. Coupled with a Na3V2(PO4)3 cathode, the energy density of the full cell can reach to 181.9 Wh kg-1 at - 40 degrees C. Based on this work, a novel strategy of high-rate activation is proposed to enhance performances of Bi-based materials in cryogenic conditions by creating new active sites for interfacial reaction under large current.

关键词： Bi nanoparticles High temperature shock High-rate activation Ultrafast charging Low-temperature sodium-ion batteries

A Novel Self-Supervised Learning Network for Binocular Disparity Estimation

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Computer Modeling in Engineering & Sciences 2025年第1期142卷 209-229页

作者： Jiawei Tian yu Zhou Xiaobing Chen Salman A.AlQahtani Hongrong Chen bo Yang Siyu Lu Wenfeng Zheng Department of Computer Science and Engineering Major in Bio Artificial IntelligenceHanyang UniversityAnsan-si15577Republic of Korea School of Electrical and Computer Engineering Louisiana State UniversityBaton RougeLA 70803USA Department of Computer Engineering College of Computer and Information SciencesKing Saud UniversityRiyadh11574Saudi Arabia School of Automation University of Electronic Science and Technology of ChinaChengdu610054China

Two-dimensional endoscopic images are susceptible to interferences such as specular reflections and monotonous texture illumination,hindering accurate three-dimensional lesion reconstruction by surgical *** study proposes a novel end-to-end disparity estimation model to address these *** approach combines a Pseudo-Siamese neural network architecture with pyramid dilated convolutions,integrating multi-scale image information to enhance robustness against lighting *** study introduces a Pseudo-Siamese structure-based disparity regression model that simplifies left-right image comparison,improving accuracy and *** model was evaluated using a dataset of stereo endoscopic videos captured by the Da Vinci surgical robot,comprising simulated silicone heart sequences and real heart video *** results demonstrate significant improvement in the network’s resistance to lighting interference without substantially increasing ***,the model exhibited faster convergence during training,contributing to overall performance *** study advances endoscopic image processing accuracy and has potential implications for surgical robot applications in complex environments.

关键词： Parallax estimation parallax regression model self-supervised learning Pseudo-Siamese neural network pyramid dilated convolution binocular disparity estimation

Deciphering the role of mtH2O2 in hepatic ischemia-reperfusion injury mechanisms with low-background super-resolution fluorogenic probe

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China Chemistry 2025年第01期 297-307页

作者： Bin Fang Limin Wang Haoqin Li Jiaxin Zhang Yang Ding Pan Pan Li bo Peng Hua bai Lin Li Frontiers Science Center for Flexible Electronics Xi'an Institute of Flexible Electronics (IFE) and Xi'an Institute of Biomedical Materials &Engineering Northwestern Polytechnical University Institute of Flexible Electronics (IFE Future Technologies) Xiamen University

Hepatic ischemia-reperfusion injury（HIRI） is characterized by mitochondrial dysfunction and oxidative stress. Monitoring mitochondrial hydrogen peroxide（mtH2O2） levels in real-time through super-resolution imaging is crucial for elucidating its distribution in live cells and its mechanism of action during HIRI. However, low-background fluorogenic probes have been overlooked in the context of super-resolution imaging. In this study, we developed a low-background fluorogenic probe（MitoWG） with the potential for super-resolution morphology-correlated mitochondrial identification to track the fluctuates of mtH2O2in HIRI. Activation of the desirable fluorescence properties of the probe by mtH2O2was confirmed using structural illumination microscopy（SIM）, enabling high-quality mitochondrial imaging with exceptional specificity and *** in mtH2O2levels were successfully observed in both cellular and rat models of HIRI. Furthermore, we associated the decline in mitochondrial redox homeostasis with accelerated mtH2O2production during HIRI, which triggered mitophagy deficiency and led to cell death. In conclusion, Mito-WG possesses excellent photophysical and low-background properties for SIM imaging, making it a promising tool for mtH2O2tracking in HIRI research and clinical diagnosis.

关键词：

同方期刊数据库

在线全文

学校读者我要写书评

暂无评论

拉萨上空大气臭氧垂直分布的高空气球探测

地球科学进展 2000年第5期15卷 522-524页

作者：石广玉白宇波岩坂泰信大桥铁弥中国科学院大气物理研究所大气科学与地球流体力学数值模拟国家重点实验室北京100029 日本名古屋大学太阳地球环境研究所

用臭氧探空仪于 1 998年 8月和 1 0月测量了在拉萨上空的臭氧垂直分布 ,并与河北香河的观测资料进行了对比。结果表明 ,拉萨上空对流层臭氧浓度较低 ,在 2 5～ 2 6km之间臭氧分压最大 ,在 30～ 34km之间混合比最大。从典型的臭氧垂直分... 详细信息

用臭氧探空仪于 1 998年 8月和 1 0月测量了在拉萨上空的臭氧垂直分布 ,并与河北香河的观测资料进行了对比。结果表明 ,拉萨上空对流层臭氧浓度较低 ,在 2 5～ 2 6km之间臭氧分压最大 ,在 30～ 34km之间混合比最大。从典型的臭氧垂直分布廓线推算出大气臭氧总含量为 2 61 .6DU。

关键词：臭氧探空臭氧分压臭氧层高空气球探测

基于数据融合分析的地下综合管廊安全监测系统

在线全文

学校读者我要写书评

暂无评论

自动化技术与应用 2019年第9期38卷 67-72页

作者：杨涛王承成张喻白博宇上海岩联工程技术有限公司

现有的地下综合管廊安全监测技术由于存在监测参数单一及监测数据无法融合分析等缺陷,无法满足地下综合管廊安全监测需求,基于此,本文提出了一种基于数据融合分析的地下综合管廊安全监测系统,系统由数据采集终端及数据处理终端组成,数... 详细信息

现有的地下综合管廊安全监测技术由于存在监测参数单一及监测数据无法融合分析等缺陷,无法满足地下综合管廊安全监测需求,基于此,本文提出了一种基于数据融合分析的地下综合管廊安全监测系统,系统由数据采集终端及数据处理终端组成,数据采集终端实时采集地下综合管廊内电力及燃气管道的相关工况数据、管廊环境及人员入侵信息,采集到的数据经电缆实时传输到数据处理终端,数据处理终端在对数据进行融合分析的基础上,对地下综合管廊的安全风险作出评估。系统加工完成后进行了现场试验,试验结果显示系统的视频显示及安全评估功能等完整,满足实际现场需求,可为综合管廊安全监测方面提供一定的借鉴。

关键词：地下综合管廊监测数据融合风险评估

Perilipin-2 mediates ferroptosis in oligodendrocyte progenitor cells and myelin injury after ischemic stroke

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第7期20卷 2015-2028页

作者： Jian Yang Jiang Wu Xueshun Xie Pengfei Xia Jinxin Lu Jiale Liu Lei bai Xiang Li Zhengquan yu Haiying Li Department of Neurosurgery&Brain and Nerve Research Laboratory The First Affiliated Hospital of Soochow UniversitySuzhouJiangsu ProvinceChina Institute of Stroke Research Soochow UniversitySuzhouJiangsu ProvinceChina

Differentiation of oligodendrocyte progenitor cells into mature myelin-forming oligodendrocytes contributes to *** of remyelination due to oligodendrocyte progenitor cell death can result in severe nerve *** is an iron-dependent form of regulated cell death caused by membrane rupture induced by lipid peroxidation,and plays an important role in the pathological process of ischemic ***,there are few studies on oligodendrocyte progenitor cell *** analyzed transcriptome sequencing data from GEO databases and identified a role of ferroptosis in oligodendrocyte progenitor cell death and myelin injury after cerebral *** analysis suggested that perilipin-2(PLIN2)was involved in oligodendrocyte progenitor cell ***2 is a lipid storage protein and a marker of hypoxia-sensitive lipid droplet *** further investigation,we established a mouse model of cerebral ischemia/*** found significant myelin damage after cerebral ischemia,as well as oligodendrocyte progenitor cell death and increased lipid peroxidation levels around the infarct *** ferroptosis inhibitor,ferrostatin-1,rescued oligodendrocyte progenitor cell death and subsequent myelin *** also found increased PLIN2 levels in the peri-infarct area that co-localized with oligodendrocyte progenitor ***2 knockdown rescued demyelination and improved neurological *** findings suggest that targeting PLIN2 to regulate oligodendrocyte progenitor cell ferroptosis may be a potential therapeutic strategy for rescuing myelin damage after cerebral ischemia.

关键词： bioinformatics bulk RNA sequencing ferroptosis ischemic stroke myelin injury oligodendrocyte progenitor cell perilipin-2 single-cell RNA sequencing