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Global trends and hotspots of type 2 diabetes in children and adolescents:A bibliometric study and visualization analysis

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World Journal of Diabetes 2025年第1期16卷 140-168页

作者： Fang-Shuo Zhang Hai-Jing li Xue Yu Yi-Ping Song Yan-Feng Ren Xuan-Zhu Qian Jia-li liu Wen-xun li Yi-Ran Huang Kuo gao School of Acupuncture-Moxibustion and Tuina Beijing University of Chinese MedicineBeijing 100029China School of Traditional Chinese Medicine Beijing University of Chinese MedicineBeijing 100029China

BACKGROUND Epidemiological surveys indicate an increasing incidence of type 2 diabetes mellitus(T2DM)among children and adolescents *** to rapid disease progression,severe long-term cardiorenal complications,a lack of effective treatment strategies,and substantial socioeconomic burdens,it has become an urgent public health issue that requires management and *** T2DM differs from adult *** a significant increase in our understanding of youth-onset T2DM over the past two decades,the related review and evidence-based content remain *** To visualize the hotspots and trends in pediatric and adolescent T2DM research and to forecast their future research *** This study utilized the terms“children”,“adolescents”,and“type 2 diabetes”,retrieving relevant articles published between 1983 and 2023 from three citation databases within the Web of Science Core Collection(SCI,SSCI,ESCI).Utilizing CiteSpace and VoSviewer software,we analyze and visually represent the annual output of literature,countries involved,and participating *** allows us to predict trends in this research *** analysis encompasses co-cited authors,journal overlays,citation overlays,time-zone views,keyword analysis,and reference analysis,*** A total of 9210 articles were included,and the annual publication volume in this field showed a steady growth *** United States had the highest number of publications and the highest *** United States also had the most research institutions and the strongest research *** global hot journals were primarily diabetes professional journals but also included journals related to nutrition,endocrinology,and *** analysis showed that research related to endothelial dysfunction,exposure risk,cardiac metabolic risk,changes in gut microbiota,the impact on comorbidities and outcomes,etc.,were emerging *** have maintained their popularity in this field,sugges

关键词： Child Adolescent Type 2 diabetes mellitus Bibliometrics Knowledge mapping Visualization CiteSpace VOSviewer

A Dispatching Method for Integrated Energy System Based on Dynamic Time-interval of Model Predictive Control

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Journal of Modern Power Systems and Clean Energy 2020年第5期8卷 841-852页

作者： xun Dou Jun Wang Zhen Wang lijuan li linquan bai Shuhui Ren Min gao IEEE College of Electrical Engineering and Control Science Nanjing Tech UniversityNanjingChina Department of Systems Engineering and Engineering Management University of North Carolina at CharlotteCharlotteUSA Falcon Computing Solutions 10880 Wilshire Blvd Suite 1132Los AngelesCA 90024USA

In integrated energy systems(IESs),traditional fixed time-interval dispatching scheme is unable to adapt to the need of dynamic properties of the transient network,demand response characteristics,dispatching time scales in energy subsystems and renewable power *** scheme may easily result in uneconomic source-grid-load-storage operations in *** this paper,we propose a dispatching method for IES based on dynamic time-interval of model predictive control(MPC).We firstly build models for energy sub-systems and multi-energy loads in the power-gas-heat ***,we develop an innovative optimization method leveraging trajectory deviation control,energy control,and cost control frameworks in MPC to handle the requirements and constraints over the timeinterval of ***,a dynamic programming algorithm is introduced to efficiently solve the proposed *** and simulation results prove the effectiveness of the method.

关键词： Dispatching scheme dynamic time-interval integrated energy system model predictive control

Establishment of Real-Time TaqMan-Fluorescence Quantitative RT-PCR Assay for Detection and Quantification of Porcine lipoprotein lipase mRNA

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Agricultural Sciences in China 2009年第10期8卷 1256-1262页

作者： lian Hong-xia LU De-xun gao Min College of Animal Science and Veterinary Medicine Henan Agricultural University Zhengzhou 450002 P.R. China Institute of Animal Nutrition Inner Mongolian Academy of Agricultural and Animal Sciences Huhhot 010031 P.R. China

Porcine lipoprotein lipase （LPL） cDNA was cloned as the standard for real-time quantifying LPL mRNA and the TaqMan-fluorescence quantitative PCR assay for detection was established. The total RNA extracted from Longissimus dorsi of porcine was reverse-transcribed to cDNA. LPL cDNA was ligated with pGM-T vector and transformed into Escherichia coli TOP10. Plasmid DNA extracted from positive clones was verified by PCR amplification and sequenced. LPL was amplified by real-time fluorescence quantitative PCR from the plasmid DNA. The concentration of DNA template purified was detected by analyzing absorbance in 260 nm and then the combined plasmid was diluted to series as standard for fluorescence quantitative PCR （FQ-PCR）. The method of LPL mRNA real-time PCR was well established, which detected as low as 103 with the linear range 10^3 to 10^10 copies. The standard curves showed high correlations （R2 = 0.9871）. A series of standards for real-time PCR analysis have been constructed successfially, and real-time TaqMan-fluorescence quantitative RT-PCR is reliable to quantitatively evaluate FQ-PCR mRNA in L. dorsi of porcine.

关键词： porcine lipoprotein lipase FQ-PCR TaqMan fluorogenic probe

Synthesis of cis-(±)-2-Hydroxymethyl-5-(Cytosine-1'-yl)-1,3-Oxathiolane (BCH-189)

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Chinese Chemical Letters 2001年第6期12卷 487-488页

作者： Ji Zhen li Xue Peng QIU lian xun gao Meng Xian DING Polymer Chemistry Laboratory Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun 130022

The target compound BCH-189 was synthesized with high yield via four steps from benzoyloxy acetylaldehyde and p-dithiane-2,5-diol as starting materials. The synthetic route is preferable to what literature reported.

关键词： Anti-HIV total synthesis BCH-189

Synthesis and Characterization of Novel Sulfonated Polyimides from 4,6-Bis（4-aminophenoxy）-naphthalene-2-sulfonic Acid

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Chemical Research in Chinese Universities 2013年第6期29卷 1225-1228页

作者： li Yu-han WANG Wei-jian JIN Ri-zhe gao lian-xun College of Food Science and Engineering Jilin Business and Technology College Changchun 130062 P.R.China State Key Laboratory of Polymer Physics and Chemistry Changchun Institute of Applied ChemistryChinese Academy of Sciences Changchun 130022 P.R.China

A novel sulfonated diamine monomer, 4,6-bis（4-arninophenoxy）-naphthalene-2-sulfonic acid（BAPNS）, was synthesized. A series of sulfonated polyimide copolymers was prepared from BAPNS, 1,4,5,8-naphthalenetetracarboxylic dianhydride（NTDA） and nonsulfonated diamine 4,4＇-diaminodiphenyl ether（ODA）. Flexible, transparent, and mechanically strong membranes were obtained. The novel sulfonated polyimide（SPI） membranes show higher conductivity, for example, SPI-100 shows a conductivity of 0.0698 S/cm at 80℃（SPI-X： Xrefers to molar fraction of BAPNS）. The membranes exhibit the permeability of methanol from 2.18×10^-7 cm2/s to 2.57×10^-7 cm2/s, which is much lower than that of Nafion（2.00×10 6 cm^2/s）. The copolymers were thermally stable up to 330℃. The sulfonated polyimide copolymers also show reasonable mechanical strength; for example, the maximum tensile strength at break of the sulfonated polyimide copolymer with 100%（molar fraction） BAPNS is 1.35 GPa under high moisture condi- tions. The optimum concentration of BAPNS was found to be 100%（molar fraction） from the view point of proton conductivity, methanol permeability, and membrane stability.

关键词： Sulfonated polyimide Proton conductivity Proton-exchange membrane

Tungsten combustion in impact initiated W-Al composite based on W(Al) super-saturated solid solution

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Defence Technology（防务技术） 2023年第7期25卷 112-120页

作者： Kong-xun Zhao xiao-hong Zhang xiao-ran Gu Yu Tang Shun li Yi-cong Ye li'an Zhu Shu-xin bai College of Aerospace Science and Engineering National University of Defense TechnologyChangsha410073China

Element W can effectively improve the density of energetic structural materials. However, W is an inert element and does not combust in air. To change the reaction characteristics of W, 60 at.% Al was introduced into W through mechanical alloying. XRD analysis shows that after 50 h of ball milling, the diffraction peak of Al completely disappears and W(Al60) super-saturated solid solution powder is obtained. Further observation by HAADF and HRTEM reveals that the W(Al60) super-saturated solid solution powder is a mixture of solid solution and amorphous phase. Based on the good thermal stability of W(Al60) alloy powder below 1000℃, W(Al60)-Al composite was synthesized by hot pressing *** initiation experiments suggest that the W(Al60)-Al composite has excellent reaction characteristics, and multiple types of tungsten oxides are detected in the reaction products, showing that the modified W is combustible in air. Due to the combustion of tungsten, the energy release rate of the W(Al60)-Al composite at speed of 1362 m/s reaches 2.71 kJ/g.

关键词： Tungsten combustion Reactive materials Super-saturated solid solution Shock-induced reactions WeAl composite

Effects of Number of Bleed Holes on Shock-Wave/Boundary-Layer Interactions in a Transonic Compressor Stator

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Journal of Thermal Science 2024年第2期33卷 611-624页

作者： li bai ZHOU xun LUO Lei DU Wei School of Energy Science and Engineering Harbin Institute of TechnologyHarbin150001China

An extensive numerical investigation is conducted to characterize the flow separation control in a transonic compressor cascade with a porous *** bleed holes are arranged on the suction surface in a single row,two staggered rows and three staggered *** each bleed scheme,five bleed pressure ratios are examined at an inlet Mach number of *** results indicate that the aerodynamic performance of the cascade is significantly improved by the porous *** the single-row scheme,the maximum reduction in total pressure losses is 57%.For the two-staggered-row and three-staggered-row schemes,there is an optimal bleed pressure ratio of 1.0,and the maximum reductions in total pressure loss are 68% and 75%,*** low loss in the cascade is due to the well-controlled boundary *** new local supersonic region created by the bleed hole is the key reason for the improved boundary *** vortex induced by side bleeding provides another mechanism for delaying flow *** the bleed holes could create multiple local supersonic regions,which reduce the range of the adverse pressure gradient that the boundary layer needs to *** is the reason why cascades with more bleed holes perform better.

关键词： transonic compressor stator shock wave/boundary layer interaction porous bleed number of bleed holes

Fatigue crack growth rate test using a frequency sweep method

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2008年第3期9卷 346-350页

作者： xun ZHOU xiao-li YU College of Mechanical and Energy Engineering Zhejiang University Hangzhou 31002 7 China

Fatigue crack propagation characteristics of a diesel engine crankshaft are studied by measuring the fatigue crack growth rate using a frequency sweep method on a resonant fatigue test rig. Based on the phenomenon that the system frequency will change when the crack becomes large, this method can be directly applied to a complex component or structure. Finite element analyses （FEAs） are performed to calibrate the relation between the frequency change and the crack size, and to obtain the natural frequency of the test rig and the stress intensity factor （SIF） of growing cracks. The crack growth rate i.e. da/dN-AK of each crack size is obtained by combining the testing-time monitored data and FEA results. The results show that the crack growth rate of engine crankshaft, which is a component with complex geometry and special surface treatment, is quite different from that of a pure material. There is an apparent turning point in the Paris＇s crack partition. The cause of the fatigue crack growth is also discussed.

关键词： Crack growth rate Residual stress Frequency sweep method Engine crankshaft Reliability

Use of the N-alkanes to Estimate Intake, Apparent Digestibility and Diet Composition in Sheep Grazing on Stipa brevifl ora Desert Steppe

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Journal of Integrative Agriculture 2014年第5期13卷 1065-1072页

作者： HU Hong-lian liU Yong-zhi li Ya-kui LU De-xun gao Min Institute of Animal Nutrition and Feed Inner Mongolia Academy of Agricultural & Animal Husbandry Sciences Inner Mongolia Prataculture Research Center Chinese Academy of Sciences Institute of Botany Chinese Academy of Sciences College of Animal and Technology Hebei North University

The application of n-alkane as markers to estimate herbage intake, apparent digestibility and species composition of diet consumed by grazing sheep was studied. Six local Mongolian sheep were used to determine dry matter （DM） intake, apparent DM digestibility and species composition of diet during summer, autumn and winter. Animals were orally dosed twice daily with n-alkane gelatin capsules containing 60 mg C32-alkane as an external marker. Diet composition was estimated by comparing the odd-chain n-alkanes pattern profile （C27-C31） of the consumed plant species with the n-alkanes fecal concentrations of grazing animals, using a non-negative least squares algorithm called EATWHAT software package. The alkane pair C32：C33 and C33 alkane were used to estimate DM intake and diet apparent DM digestibility, respectively. The results showed that daily dry matter intake of the sheep were 1.77, 1.61 and 1.18 kg d-1 in summer, autumn and winter, respectively. Apparent DM digestibility, crude protein （CP）, metabolizable energy （ME） and neutral detergent fiber （NDF） intake of diet consumed by sheep decreased significantly （P〈0.01） from summer to winter, with no evident changes in ADF and ADL intake. Diet composition indicated Artemisia frigida Willd was the most dominant diet component, contributed 79.68, 68.12 and 86.26% of sheep＇s diets in summer, autumn and winter, respectively. Cleistogenes songorica Ohwi and Convolvulus arnmannii Desr were the important components of the diet. Although Stipa breviflora Griseb is one of the main plant species in the study area, the sheep rarely choosed it. The study indicated that CP and ME in diet consumed by sheep were deficient in winter. Therefore, appropriate supplementation strategies should be indispensable during this period.

关键词： n-alkanes diet composition intake apparent digestibility sheep