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A machine learning framework for damage mechanism identification from acoustic emissions in unidirectional SiC/SiC composites

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npj Computational Materials 2021年第1期7卷 1326-1335页

作者： C.Muir b.swaminathan K.Fields A.S.Almansour K.Sevener C.Smith M.Presby J.D.Kiser T.M.Pollock S.Daly Materials University of California-Santa BarbaraSanta BarbaraCAUSA Mechanical Engineering University of California-Santa BarbaraSanta BarbaraCAUSA NASA Glenn Research Center ClevelandOHUSA Materials Science and Engineering University of Michigan-Ann ArborAnn ArborMIUSA

In this work,we demonstrate that damage mechanism identification from acoustic emission(AE)signals generated in minicomposites with elastically similar constituents is *** waveforms were generated by SiC/SiC ceramic matrix minicomposites(CMCs)loaded under uniaxial tension and recorded by four sensors(two models with each model placed at two ends).Signals were encoded with a modified partial power scheme and subsequently partitioned through spectral *** cracking and fiber failure were identified based on the frequency information contained in the AE event they produced,despite the similar constituent elastic properties of the matrix and ***,the resultant identification of AE events closely followed CMC damage chronology,wherein early matrix cracking is later followed by fiber breaks,even though the approach is fully domain-knowledge ***,the partitions were highly precise across both the model and location of the sensors,and the partitioning was *** presented approach is promising for CMCs and other composite systems with elastically similar constituents.

关键词： composites damage mechanism

Efficacy of stromal vascular fraction for knee osteoarthritis:A prospective,single-centre,non-randomized study with 2 years follow-up

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World Journal of Orthopedics 2024年第5期15卷 457-468页

作者： Madhan Jeyaraman Naveen Jeyaraman Tarun Jayakumar swaminathan Ramasubramanian Rajni Ranjan Saurabh Kumar Jha Ashim Gupta Department of Orthopaedics ACS Medical College and HospitalDr MGR Educational and Research InstituteChennaiTamil Nadu 600077India Department of biotechnology School of Engineering and TechnologySharda UniversityGreater NoidaUttar Pradesh 201310India Department of Orthopaedics and Regenerative Medicine South Texas Orthopaedic Research InstituteLaredoTX 78045United States Department of Orthopaedics KIMS-Sunshine HospitalHyderabadTelangana 500032India Department of Orthopaedics Government Medical CollegeOmandurar Government EstateChennaiTamil Nadu 600002India Department of Orthopaedics School of Medical Sciences and ResearchSharda UniversityGreater NoidaUttar Pradesh 201306India Department of Zoology Kalindi CollegeUniversity of DelhiNew Delhi 110008India Department of Orthopaedics and Regenerative Medicine Regenerative OrthopaedicsNoida 201301Uttar PradeshIndia Department of Orthopaedics and Regenerative Medicine Future BiologicsLawrencevilleGA 30043United States Department of Orthopaedics and Regenerative Medicine BioIntegrateLawrencevilleGA 30043United States

bACKGROUND Current osteoarthritis(OA)treatments focus on symptom relief without addressing the underlying disease *** regenerative medicine,current treatments have *** regenerative medicine,more research is needed for intra-articular stromal vascular fraction(SVF)injections in OA,including dosage optimization,long-term efficacy,safety,comparisons with other treatments,and mechanism *** To compare the efficacy of intra-articular SVF with corticosteroid(ICS)injections in patients with primary knee *** The study included 50 patients with Kellgren-Lawrence grades II and III *** were randomly assigned(1:1)to receive either a single intra-articular SVF injection(group A)or a single intra-articular ICS(triamcinolone)(group b)*** were followed up at 1,3,6,12,and 24 *** analog score(VAS)and International Knee Documentation Committee(IKDC)scores were administered before the procedure and at all *** safety of SVF in terms of adverse and severe adverse events was *** analysis was performed with SPSS Version 26.0,IbM Corp,Chicago,IL,United *** both groups had similar demographics and baseline clinical ***-up showed minor patient loss,resulting in 23 and 24 in groups A and b *** A experienced a notable reduction in pain,with VAS scores decreasing from 7.7 to 2.4 over 24 months,compared to a minor reduction from 7.8 to 6.2 in Group *** difference in pain reduction in group A was statistically significant from the third month ***,Group A showed significant improvements in knee functionality,with IKDC scores rising from 33.4 to 83.10,whereas Group b saw a modest increase from 36.7 to *** improvement in Group A was statistically significant from 6 months and maintained through 24 *** Our study demonstrated that intra-articular administration of SVF can lead to reduced pain and improved knee function in pa

关键词： Knee osteoarthritis Adipose tissue Stromal vascular fraction Regenerative medicine Orthobiologics

Performance analysis of new word weighting procedures for opinion mining

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Frontiers of Information Technology & Electronic Engineering 2016年第11期17卷 1186-1198页

作者： G.R.bRINDHA P.swaminathan b.SANTHI School of Computing SASTRA University

The proliferation of forums and blogs leads to challenges and opportunities for processing large amounts of information. The information shared on various topics often contains opinionated words which are qualitative in nature. These qualitative words need statistical computations to convert them into useful quantitative data. This data should be processed properly since it expresses opinions. Each of these opinion bearing words differs based on the significant meaning it conveys. To process the linguistic meaning of words into data and to enhance opinion mining analysis, we propose a novel weighting scheme, referred to as inferred word weighting(IWW). IWW is computed based on the significance of the word in the document(SWD) and the significance of the word in the expression(SWE) to enhance their performance. The proposed weighting methods give an analytic view and provide appropriate weights to the words compared to existing methods. In addition to the new weighting methods, another type of checking is done on the performance of text classification by including stop-words. Generally, stop-words are removed in text processing. When this new concept of including stop-words is applied to the proposed and existing weighting methods, two facts are observed:(1) Classification performance is enhanced;(2) The outcome difference between inclusion and exclusion of stop-words is smaller in the proposed methods, and larger in existing methods. The inferences provided by these observations are discussed. Experimental results of the benchmark data sets show the potential enhancement in terms of classification accuracy.

关键词： Inferred word weight Opinion mining Supervised classification Support vector machine(SVM) Machine learning

Unique and hierarchically structured novel Co3O4/NiO nanosponges with superior photocatalytic activity against organic contaminants

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Frontiers of Materials Science 2017年第4期11卷 375-384页

作者： Vahini RAJA Senthil Kumar PUVANESWARAN Karuthapandian swaminathan Department of Chemistry VHNSN College Virudhunagar-626001 Tamilnadu India

In the present study, novel Co3O4/NiO nanosponges designed for the photocatalytic degradation of organic contaminants were synthesized by a simple precipitation technique. The formation of sponge-like nanostructures was clearly evident through the TEM analysis. The photocatalytic efficiency was tested against rhodamine b （Rhb） and congo red （CR） dye solutions. Co3O4/NiO nanosponges showed excellent and enhanced photocatalytic efficacy compared to those of Co3O4, NiO nanoparticles, and standards like Ti02 and ZnO. The influence of paramount important operational parameters was explored and the conditions for the best photocatalytic efficiency were optimized. The trapping experiment revealed that the reactive oxygen species （ROS） identified was · OH radical. These findings certainly open up a new way for synthesizing a morphology dependent photocatalyst.

关键词： Co3O4/NiO nanosponges photocatalytic efficacy visible light

Self-assembled multifunctional nanotheranostics against circulating tumor clusters in metastatic breast cancer

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Acta Pharmaceutica Sinica b 2023年第4期13卷 1711-1725页

作者： Ramya Dhandapani swaminathan Sethuraman Uma Maheswari Krishnan Anuradha Subramanian Centre for Nanotechnology&Advanced biomaterials School of Chemical&BiotechnologySASTRA Deemed UniversityThanjavur 613401India

Circulating tumor clusters(CTC)disseminating from the primary tumor are responsible for secondary tumor formation where the conventional treatments such as chemotherapy and radiotherapy does not prevent the metastasis at locally advanced stage of breast *** this study,a smart nanotheranostic system has been developed to track and eliminate the CTCs before it can colonize at a new site,which would reduce metastatic progression and increase the five-year survival rate of the breast cancer *** multiresponsive(magnetic hyperthermia and pH)nanomicelles incorporated with NIR fluorescent superparamagnetic iron oxide nanoparticles were developed based on self-assembly for dual modal imaging and dual toxicity for spontaneous killing of CTCs in blood stream.A heterogenous tumor clusters model was developed to mimic the CTCs isolated from breast cancer *** nanotheranostic system was further evaluated for the targeting property,drug release kinetics,hyperthermia and cytotoxicity against developed CTC model in *** vivo model in bALb/c mice equivalent to stageⅢandⅣhuman metastatic breast cancer was developed to evaluate the biodistribution and therapeutic efficacy of micellar nanotheranostic *** CTCs in blood stream and low distant organ metastasis after treatment with the nanotheranostic system demonstrates its potential to capture and kill the CTCs that minimize the secondary tumor formation at distant sites.

关键词： Self-assembly Hybrid nanotheranostic system Circulating tumor clusters Advanced breast cancer Cancer stem cells Heterogenous clusters SPIONs NIR Metastasis CD44

Moisture-driven phase transition for improved perovskite solar cells with reduced trap-state density

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Nano Research 2017年第4期10卷 1413-1422页

作者： swaminathan Venkatesan Fang Hao Junyoung Kim Yaoguang Rong Zhuan Zhu Yanliang Liang Jiming bao Yan Yao Department of Electrical and Computer Engineering and Materials Science and Engineering Program University of Houston Houston Texas 77204 USA Texas Center for Superconductivity at the University of Houston Houston Texas 77204 USA

We report a mechanistic understanding of a moisture-driven intermediate-phase transition that improves the quality of perovskite thin films based on a lead-acetate precursor, improving the power-conversion effidency. We clarify the composition of the intermediate phase and attribute the transition of this phase to the hygroscopic nature of the organic product, i.e., methylammonium acetate. Thermal annealing aids in the coarsening of the grains. These decoupled processes result in better crystal formation with a lower spatial and energetic distribution of traps. Thermal annealing of the films without exposure to air results in a faster intermediate-phase transition and grain coarsening, which occur simultaneously, leading to disorder in the films and a higher deep trap-state density. Our results indicate the need for a humid environment for the growth of high-quality perovskite films and provide insight into intermediate-phase dissociation and conversion kinetics. Thus, they are useful for the large-scale production of effident solution-processed perovskite solar cells.

关键词： perovskite solar cells phase transition moisture treatment film growth

帕里骨化醇单用以及联合成纤维细胞生长因子23受体抑制剂在慢性肾功能衰竭中的心脏保护作用:试验与临床研究

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中华高血压杂志(中英文) 2019年第11期 1098-1098页

作者： Czaya b Seeherunvong W Singh S Yanucil C Ruiz P Qui-roz Y Grabner A Katsoufis C swaminathan S Abitbol C Rodriguez-Iturbe b Faul C Freundlich M

在尿毒症动物的研究中发现,维生素D受体(vitamin D receptor,VDR)激动剂如帕里骨化醇(paricalcitol,Pc)可减轻心肌肥大,但目前在慢性肾脏病患者中尚未观察到该作用是否存在。成纤维细胞生长因子23(fibroblast growth factor 23,FGF23)... 详细信息

在尿毒症动物的研究中发现,维生素D受体(vitamin D receptor,VDR)激动剂如帕里骨化醇(paricalcitol,Pc)可减轻心肌肥大,但目前在慢性肾脏病患者中尚未观察到该作用是否存在。成纤维细胞生长因子23(fibroblast growth factor 23,FGF23)水平升高可激活心肌钙调神经磷酸酶/活化T细胞核因子(nuclear factor of activated T cell,NFAT)信号通路,引起心肌肥厚,可能对抗VDR激动剂治疗的心肌保护

关键词：成纤维细胞生长因子骨化醇心脏保护作用慢性肾功能衰竭临床研究受体抑制剂

The Effect of Aprotinin on Outcome after Coronary-Artery bypass Grafting

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The Effect of Aprotinin on Outcome after Coronary-Artery Byp...