检索结果-南通市图书馆

Phase separation of S-RNase promotes self-incompatibility in Petunia hybrida

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Integrative Plant biology 2024年第5期66卷 986-1006页

作者： Huayang Tian Hongkui Zhang Huaqiu Huang Yu'e Zhang Yongbiao Xue The State Key Laboratory of Plant Cell and Chromosome engineering Institute of Genetics and Developmental Biologythe Chinese Academy of SciencesBeijing 100101China University of the Chinese Academy of Sciences Beijing 100049China beiing Institute of Genomics Chinese Academy of SciencesNational Center for BioinformationBeijing 100101China

Self-incompatibility(SI)is an intraspecific reproductive barrier widely present in *** SI system with the broadest occurrence in angiosperms is based on an S-RNase linked to a cluster of multiple S-locus F-box(SLF)genes found in the Solanaceae,Plantaginaceae,Rosaceae,and *** studies reveal that non-self S-RNase is degraded by the Skip Cullin F-box(SCF)SLF-mediated ubiquitin–proteasome system in a collaborative manner in Petunia,but how self-RNase functions largely remains ***,we show that S-RNases form S-RNase condensates(SRCs)in the self-pollen tube cytoplasm through phase separation and the disruption of SRC formation breaks SI in self-incompatible Petunia *** further find that the pistil SI factors of a small asparagine-rich protein HT-b and thioredoxin h together with a reduced state of the pollen tube all promote the expansion of SRCs,which then sequester several actin-binding proteins,including the actin polymerization factor PhAbRACL,the actin polymerization activity of which is reduced by S-RNase in ***,we find that S-RNase variants lacking condensation ability fail to recruit PhAbRACL and are unable to induce actin foci formation required for pollen tube growth *** together,our results demonstrate that phase separation of S-RNase promotes SI response in ***,revealing a new mode of S-RNase action.

关键词： self-incompatibility S-RNase phase separation

在线全文

学校读者我要写书评

暂无评论

夏洛的网(二)

疯狂英语（初中天地） 2024年第3期 54-55页

作者： e.b.White 不详

在农场中,时间一天天过去,威尔伯的日常生活也变得悠闲而惬意。然而,老羊的突然拜访,却让威尔伯和他的伙伴芬震惊不已,同时也让威尔伯陷入了恐惧和绝望之中。很多天过去了,威尔伯长了又长。他一天的食量相当于三头猪的食量了。他把时间... 详细信息

在农场中,时间一天天过去,威尔伯的日常生活也变得悠闲而惬意。然而,老羊的突然拜访,却让威尔伯和他的伙伴芬震惊不已,同时也让威尔伯陷入了恐惧和绝望之中。很多天过去了,威尔伯长了又长。他一天的食量相当于三头猪的食量了。他把时间都花在躺着、小睡和做美梦上。

关键词：威尔伯日常生活悠闲夏洛的网食量

在线全文

学校读者我要写书评

暂无评论

第一章早饭前（节选）

疯狂英语(新悦读) 2024年第7期 43-45+77页

作者： e.b.White

《夏洛的网》是一个关于友情的童话故事。在朱克曼家的谷仓里，生活着一群快乐的动物。其中，小猪威尔伯和蜘蛛夏洛感情最好。然而，一个最可怕的消息打破了谷仓的平静：威尔伯未来的命运竟是成为熏肉火腿。作为一只猪，威尔伯似乎只能...

《夏洛的网》是一个关于友情的童话故事。在朱克曼家的谷仓里，生活着一群快乐的动物。其中，小猪威尔伯和蜘蛛夏洛感情最好。然而，一个最可怕的消息打破了谷仓的平静：威尔伯未来的命运竟是成为熏肉火腿。作为一只猪，威尔伯似乎只能接受任人宰割的命运，然而，看似渺小的夏洛却说：“我救你。”于是，夏洛用自己的丝在猪栏上织出了被人类视为奇迹的网上文字，这也彻底扭转了威尔伯的命运——威尔伯在集市的大赛中赢得特别奖，也赢得了一个安享天年的未来。但这时，夏洛的生命却走到了尽头……之后，威尔伯带着悲伤和感恩抚养了夏洛的孩子。

关键词：

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

夏洛的网(五)

疯狂英语（初中天地） 2024年第6期 52-54页

作者： e.b.White 不详

这些文字彻底改变了威尔伯的命运,让威尔伯在集市的大赛上赢得特别奖,保障了一个安享天年的未来。但在这时,夏洛的生命也走到了尽头……“可能有一点点累吧。但是我感到很满足。你今早在裁判场上的成功,在很小的程度上,也可以算是我的... 详细信息

这些文字彻底改变了威尔伯的命运,让威尔伯在集市的大赛上赢得特别奖,保障了一个安享天年的未来。但在这时,夏洛的生命也走到了尽头……“可能有一点点累吧。但是我感到很满足。你今早在裁判场上的成功,在很小的程度上,也可以算是我的成功。你的将来没危险了。你会无忧无虑地活下去的,威尔伯。现在没什么能伤害你了。这个秋天会变短,也会变冷。叶子们也会从树上摇落的。圣诞节会来,然后就是飘飘的冬雪。你将活着看到那个美丽的冰雪世界,因为你对朱克曼有很重要的意义,他再也不会想伤害你了。冬天将过去,白天又会变长,草场池塘里的冰也会融化的。百灵鸟又会回来唱歌,青蛙也将醒来,又会吹起暖暖的风。所有这些美丽的景色,所有这些动听的声音,所有这些好闻的气味,都将等着你去欣赏呢,威尔伯--这个可爱的世界,这些珍贵的日子……”

关键词：威尔伯冰雪世界活下去朱克曼圣诞节夏洛的网

在线全文

学校读者我要写书评

暂无评论

夏洛的网(一)

疯狂英语（初中天地） 2024年第5期 55-56页

作者： e.b.White 不详

在朱克曼家的谷仓里,这是威尔伯与夏洛的第一次友好交流。这段对话揭示了两个不同物种之间可能发展出深厚友谊的种子,为这个经典故事的展开奠定了基础。

关键词：经典故事威尔伯朱克曼夏洛的网友好交流深厚友谊

Additively manufactured Ti–Ta–Cu alloys for the next-generation load-bearing implants

在线全文

学校读者我要写书评

暂无评论

International Journal of extreme Manufacturing 2024年第1期6卷 353-374页

作者： Amit bandyopadhyay Indranath Mitra Sushant Ciliveri Jose D Avila William Dernell Stuart b Goodman Susmita bose W.M.Keck biomedical Materials Research Laboratory School of Mechanical and Materials EngineeringWashington State UniversityPullmanWA 99164United States of America Veterinary Clinical Sciences College of Veterinary MedicineWashington State UniversityPullmanWA 99164United States of America Department of Orthopedic Surgery Stanford University Medical CenterRedwood CityCA 94063United States of America

bacterial colonization of orthopedic implants is one of the leading causes of failure and clinical complexities for load-bearing metallic implants. Topical or systemic administration of antibiotics may not offer the most efficient defense against colonization, especially in the case of secondary infection, leading to surgical removal of implants and in some cases even limbs. In this study, laser powder bed fusion was implemented to fabricate Ti3Al2V alloy by a 1:1 weight mixture of CpTi and Ti6Al4V powders. Ti-Tantalum(Ta)–Copper(Cu) alloys were further analyzed by the addition of Ta and Cu into the Ti3Al2V custom alloy. The biological,mechanical, and tribo-biocorrosion properties of Ti3Al2V alloy were evaluated. A 10 wt.% Ta(10Ta) and 3 wt.% Cu(3Cu) were added to the Ti3Al2V alloy to enhance biocompatibility and impart inherent bacterial resistance. Additively manufactured implants were investigated for resistance against Pseudomonas aeruginosa and Staphylococcus aureus strains of bacteria for up to 48 h. A 3 wt.% Cu addition to Ti3Al2V displayed improved antibacterial efficacy, i.e.78%–86% with respect to CpTi. Mechanical properties for Ti3Al2V–10Ta–3Cu alloy were evaluated, demonstrating excellent fatigue resistance, exceptional shear strength, and improved tribological and tribo-biocorrosion characteristics when compared to Ti6Al4V. In vivo studies using a rat distal femur model revealed improved early-stage osseointegration for alloys with10 wt.% Ta addition compared to CpTi and Ti6Al4V. The 3 wt.% Cu-added compositions displayed biocompatibility and no adverse infammatory response in vivo. Our results establish the Ti3Al2V–10Ta–3Cu alloy’s synergistic effect on improving both in vivo biocompatibility and microbial resistance for the next generation of load-bearing metallic implants.

关键词： Ti6Al4V load-bearing implants additive manufacturing 3D printing antibacterial performance

Storylines of family medicine Ⅸ:people and places—diverse populations and locations of care

在线全文

学校读者我要写书评

暂无评论

Family Medicine and Community Health 2024年第S3期12卷 79-88页

作者： William b Ventres Leslie A Stone emad R Abou-Arab Julio Meza David S buck Jerome W Crowder Jennifer Y C edgoose Alexander brown ellen J Plumb Amber K Norris Jay J Allen Lauren e Giammar John e Wood Scott M Dickson G Austin brown Family and Preventive Medicine University of Arkansas for Medical Sciences College of MedicineLittle RockArkansasUSA Family Medicine University of Michigan Medical SchoolAnn ArborMichiganUSA Family Medicine University of California Los AngelesDavid Geffen School of MedicineLos AngelesCaliforniaUSA Community Medicine University of HoustonTilman J Fertitta Family College of MedicineHoustonTexasUSA Social and behavioral Sciences University of HoustonTilman J Fertitta Family College of MedicineHoustonTexasUSA Family Medicine and Community Health University of Wisconsin-Madison School of Medicine and Public HealthMadisonWisconsinUSA NH Dartmouth Family Medicine Residency ConcordNew HampshireUSA San Francisco VA Medical Center San FranciscoCaliforniaUSA Duluth Family Medicine Residency Program University of Minnesota Medical School Duluth CampusDuluthMinnesotaUSA UAMS Northeast Regional Campus Family Medicine Residency Program JonesboroArkansasUSA Cascades east Family Medicine Residency Program Oregon Health&Science University School of MedicineKlamath FallsOregonUSA

Storylines of Family Medicine is a 12-part series of thematically linked mini-essays with accompanying illustrations that explore the many dimensions of family medicine as interpreted by individual family physicians and medical educators in the USA and elsewhere around the ***‘Ⅸ:people and places—diverse populations and locations of care’,authors address the following themes:‘LGbTQIA+health in family medicine’,‘A family medicine approach to substance use disorders’,‘Shameless medicine for people experiencing homelessness’,“Difficult”encounters—finding the person behind the patient’,‘Attending to patients with medically unexplained symptoms’,‘Making house calls and home visits’,‘Family physicians in the procedure room’,‘Robust rural family medicine’and‘Full-spectrum family medicine’.May readers appreciate the breadth of family medicine in these essays.

关键词： illustration family dimensions

Storylines of family medicine Ⅷ:clinical approaches

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Family Medicine and Community Health 2024年第S03期12卷 70-78页

作者： William b Ventres Leslie A Stone Lauren e Gibson-Oliver elizabeth Kyle Meehan Mari A Ricker David Loxterkamp Stacy A Ogbeide Frank V deGruy Megan R Mahoney Steven Lin Clare MacRae Stewart W Mercer Family and Preventive Medicine University of Arkansas for Medical Sciences College of MedicineLittle RockArkansasUSA Family and Community Medicine The University of Arizona College of Medicine-TucsonTucsonArizonaUSA bucksport Regional Health Center BucksportMaineUSA Family and Community Medicine UT Health San Antonio Long School of MedicineSan AntonioTexasUSA eugene S.Farley Jr.Health Policy CenterUniversity of Colorado Anschutz Medical Campus School of MedicineAuroraColoradoUSA Family and Community Medicine University of California San Francisco School of MedicineSan FranciscoCaliforniaUSA Division of Primary Care and Population Health Stanford MedicinePalo AltoCaliforniaUSA Usher Institute Edinburgh Medical SchoolUniversity of EdinburghEdinburghUK

Storylines of Family Medicine is a 12-part series of thematically linked mini-essays with accompanying illustrations that explore the many dimensions of family medicine as interpreted by individual family physicians and medical educators in the USA and elsewhere around the ***‘Ⅷ:clinical approaches’,authors address the following themes:‘evaluation,diagnosis and managementⅠ—toward a working diagnosis’,‘evaluation,diagnosis and managementⅡ—process steps’,‘Interweaving integrative medicine and family medicine’,‘Halfway—the art of clinical judgment’,‘Seamless integration in family medicine—team-based care’,‘Technology—uncovering stories from noise’and‘Caring for patients with multiple long-term conditions’.May readers recognise in these essays the uniqueness of a family medicine approach to care.

关键词： uniqueness dimensions illustration

Progression of e-ticketing implementation for state transportation agencies for asphalt materials

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Road engineering 2024年第1期4卷 80-92页

作者： Joshua Withrow Gabriel b.Dadi Hala Nassereddine Department of Civil engineering University of KentuckyLexingtonKY 40506USA Kentucky Transportation Cabinet FrankfortKY 40622USA

e-ticketing,which has been promoted by the Federal Highway Administration(FHWA)“every day counts”(eDC)initiative,utilizes software applications to digitally track and store information regarding highway construction materials paid by state transportation agencies(STAs)by weight in unit bid contract *** often face implementation barriers such as institutional inertia,or the resistance by stakeholders to adopt changes from the status quo,including new *** purpose of this paper is to determine the progression of STA e-ticketing policy adoption,specifically with a focus on asphalt paving operations,due to the COVID-19 *** accomplish this research effort,previous FHWA data,National Cooperative Highway Research Program(NCHRP)data,and other literatures are reviewed to determine an implementation *** data is collected from the American Association of State Highway and Transportation Officials Committee on Con-struction to gain current feedback from STAs and their highway contractor partners after the COVID-19 ***,a case study featuring the Kentucky Transportation Cabinet(KYTC),the Kentucky Association of Highway Contractors(KAHC),and the Plantmix Asphalt Industry of Kentucky(PAIKY)is performed to provide more in-depth *** major finding includes a statistically significant result indicating increased imple-mentation of e-ticketing for asphalt operations within the last two years,along with noting benefits including employee safety,task loading,and project documentation along with concerns regarding cellular connectivity and procurement *** findings indicate the importance of STAs investing in partnership with con-tractors to improve stakeholder buy-in before proceeding towards e-ticketing adoption.

关键词： Asphalt paving Construction inspection e-ticketing COVID-19