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Search for two-neutrino double-beta decay of^(136)Xe to the 0^(+)_(1)excited state of 136ba with the complete EXO-200 dataset

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Chinese Physics C 2023年第10期47卷 1-9页

作者： S.Al Kharusi G.Anton I.badhrees P.S.barbeau D.beck V.belov T.bhatta M.breidenbach T.brunner G.F.Cao W.R.Cen C.Chambers b.cleveland M.Coon A.Craycraft T.Daniels L.Darroch S.J.Daugherty J.Davis S.Delaquis A.Der Mesrobian-Kabakian R.DeVoe J.Dilling A.Dolgolenko M.J.Dolinski J.Echevers W.Fairbank Jr. D.Fairbank J.Farine S.Feyzbakhsh P.Fierlinger Y.S.Fu D.Fudenberg P.Gautam R.Gornea G.Gratta C.Hall E.V.Hansen J.Hoessl P.Hufschmidt M.Hughes A.Iverson A.Jamil C.Jessiman M.J.Jewell A.Johnson A.Karelin L.J.Kaufman T.Koffas R.Krücken A.Kuchenkov K.S.Kumar Y.Lan A.Larson b.G.Lenardo D.S.Leonard G.S.Li S.Li Z.Li C.Licciardi Y.H.Lin R.MacLellan T.McElroy T.Michel b.Mong D.C.Moore K.Murray O.Njoya O.Nusair A.Odian I.Ostrovskiy A.Perna A.Piepke A.Pocar F.Retière A.L.Robinson P.C.Rowson J.Runge S.Schmidt D.Sinclair K.Skarpaas A.K.Soma V.Stekhanov M.Tarka S.Thibado J.Todd T.Tolba T.I.Totev R.Tsang b.Veenstra V.Veeraraghavan P.Vogel J.-L.Vuilleumier M.Wagenpfeil J.Watkins M.Weber L.J.Wen U.Wichoski G.Wrede S.X.Wu Q.Xia D.R.Yahne L.Yang Y.-R.Yen O.Ya.Zeldovich T.Ziegler 无 Physics Department McGill UniversityMontrealQuebec H3A 2T8Canada Erlangen Centre for Astroparticle Physics(ECAP) Friedrich-Alexander-University Erlangen-NürnbergErlangen 91058Germany Physics Department Carleton UniversityOttawaOntario K1S 5B6Canada Department of Physics Duke Universityand Triangle Universities Nuclear Laboratory(TUNL)DurhamNorth Carolina 27708USA Physics Department University of IllinoisUrbana-ChampaignIllinois 61801USA Institute for Theoretical and Experimental Physics named by A.I.Alikhanov of National Research Centre“Kurchatov Institute” Moscow 117218Russia Department of Physics University of South DakotaVermillionSouth Dakota 57069USA SLAC National Accelerator Laboratory Menlo ParkCalifornia 94025USA TRIUMF VancouverBritish Columbia V6T 2A3Canada Institute of High Energy Physics Beijing 100049China Department of Physics Laurentian UniversitySudburyOntario P3E 2C6Canada Physics Department Colorado State UniversityFort CollinsColorado 80523USA Department of Physics and Physical Oceanography University of North Carolina at WilmingtonWilmingtonNC 28403USA Physics Department and CEEM Indiana UniversityBloomingtonIndiana 47405USA Physics Department Stanford UniversityStanfordCalifornia 94305USA Department of Physics Drexel UniversityPhiladelphiaPennsylvania 19104USA Amherst Center for Fundamental Interactions and Physics Department University of MassachusettsAmherstMA 01003USA Technische Universität München Physikdepartment and Excellence Cluster UniverseGarching 80805Germany Physics Department University of MarylandCollege ParkMaryland 20742USA Department of Physics and Astronomy University of AlabamaTuscaloosaAlabama 35487USA Wright Laboratory Department of PhysicsYale UniversityNew HavenConnecticut 06511USA IbS Center for Underground Physics Daejeon 34126Korea Department of Physics and Astronomy Stony Brook UniversitySUNYStony BrookNew York 11794USA Kellogg Lab CaltechPasadenaCalifornia 91125USA LHEP Albert Einstein CenterUniversi

A new search for two-neutrino double-beta(2νββ)decay of^(136)Xe to the 0+1 excited state of 136ba is performed with the full EXO-200 dataset.A deep learning-based convolutional neural network is used to discriminate signal from background *** detection efficiency is increased relative to previous searches by EXO-200 by more than a factor of *** the addition of the Phase II dataset taken with an upgraded detector,the median 90%confidence level half-life sensitivity of 2νββdecay to the 0+1 state of 136ba is 2.9×10^(24)yr using a total^(136)Xe exposure of 234.1 kg *** statistically significant evidence for 2νββdecay to the 0^(+)_(1)state is observed,leading to a lower limit of T2ν1/2(0^(+)→0^(+)_(1))>1.4×10^(24)yr at 90%confidence level,improved by 70%relative to the current world's best constraint.

关键词： EXO-200 experiment neutrinoless double beta decay excited state

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Search for two-neutrino double-beta decay of 136Xe to the 01+excited state of136ba with the complete EXO-200 dataset

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Chinese Physics C 2023年第10期47卷 5-13页

作者： S.Al Kharusi G.Anton I.badhrees P.S.barbeau D.beck V.belov T.bhatta M.breidenbach T.brunner G.F.Cao W.R.Cen C.Chambers b.cleveland M.Coon A.Craycraft T.Daniels L.Darroch S.J.Daugherty J.Davis S.Delaquis A.Der Mesrobian-Kabakian R.De Voe J.Dilling A.Dolgolenko M.J.Dolinski J.Echevers W.Fairbank Jr. D.Fairbank J.Farine S.Feyzbakhsh P.Fierlinger Y.S.Fu D.Fudenberg P.Gautam R.Gornea G.Gratta C.Hall E.V.Hansen J.Hoessl P.Hufschmidt M.Hughes A.Iverson A.Jamil C.Jessiman M.J.Jewell A.Johnson A.Karelin L.J.Kaufman T.Koffas R.Krücken A.Kuchenkov K.S.Kumar Y.Lan A.Larson b.G.Lenardo D.S.Leonard G.S.Li S.Li Z.Li C.Licciardi Y.H.Lin R.Mac Lellan T.Mc Elroy T.Michel b.Mong D.C.Moore K.Murray O.Njoya O.Nusair A.Odian I.Ostrovskiy A.Perna A.Piepke A.Pocar F.Retière A.L.Robinson P.C.Rowson J.Runge S.Schmidt D.Sinclair K.Skarpaas A.K.Soma V.Stekhanov M.Tarka S.Thibado J.Todd T.Tolba T.I.Totev R.Tsang b.Veenstra V.Veeraraghavan P.Vogel J.-L.Vuilleumier M.Wagenpfeil J.Watkins M.Weber L.J.Wen U.Wichoski G.Wrede S.X.Wu Q.Xia D.R.Yahne L.Yang Y.-R.Yen O.Ya.Zeldovich T.Ziegler EXO-200 Collaboration Physics Department McGill University Erlangen Centre for Astroparticle Physics (ECAP) Friedrich-Alexander-University Erlangen-Nürnberg Physics Department Carleton University King Abdulaziz City for Science and Technology Department of Physics Duke University and Triangle Universities Nuclear Laboratory (TUNL) Physics Department University of Illinois Institute for Theoretical and Experimental Physics named by A.I.Alikhanov of National Research Centre “Kurchatov Institute” a division of National Research Center “Kurchatov Institute” Department of Physics University of South Dakota Department of Physics and Astronomy University of Kentucky SLAC National Accelerator Laboratory TRIUMF Institute of High Energy Physics Witmem Technology Co. Ltd. Department of Physics Laurentian University Also at SNOLAb Physics Department Colorado State University Department of Physics and Physical Oceanography University of North Carolina at Wilmington Physics Department and CEEM Indiana University Carleton University Commissariat àl’Energie Atomique et auxénergies alternatives Physics Department Stanford University Department of Physics Drexel University University of California Amherst Center for Fundamental Interactions and Physics Department University of Massachusetts Technische Universit?t München Physikdepartment and Excellence Cluster Universe Qventus Department of Physics University of Virginia Physics Department University of Maryland Department of Physics at the University of California Department of Physics and Astronomy University of Alabama Wright Laboratory Department of Physics Yale University Department of Physics Princeton University IbS Center for Underground Physics Physics Department University of California SNOLAb Department of Physics and Astronomy Stony Brook University SUNY SCIPP University of California Institute for Experimental Physics Hamburg University Department of Physics and Astronomy Iowa State University Kellogg Lab Caltech LHEP Albert Einstein Center University of Ber

A new search for two-neutrino double-beta(2vββ) decay of136Xe to the 01+excited state of136ba is performed with the full EXO-200 dataset.A deep learning-based convolutional neural network is used to discriminate signal from background *** detection efficiency is increased relative to previous searches by EXO-200 by more than a factor of *** the addition of the Phase Ⅱ dataset taken with an upgraded detector,the median 90%confidence level half-life sensitivity of 2vββ decay to the 01+state of136ba is 2.9 × 1024yr using a total136Xe exposure of 234.1 kg *** statistically significant evidence for 2vββ decay to the 01+state is observed,leading to a lower limit of T1/22v(0+→01+)>1.4×1024yr at 90% confidence level,improved by 70% relative to the current world’s best constraint.

关键词： EXO-200 experiment neutrinoless double beta decay excited state

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VISION-iT:A Framework for Digitizing bubbles and Droplets

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Energy and AI 2024年第1期15卷 26-35页

作者： Youngjoon Suh Sanghyeon Chang Peter Simadiris Tiffany b.Inouye Muhammad Jahidul Hoque Siavash Khodakarami Chirag Kharangate Nenad Miljkovic Yoonjin Won Department of Mechanical and Aerospace Engineering University of CaliforniaIrvine4200 Engineering GatewayCA 92617-2700USA Department of Electrical Engineering and Computer Science University of CaliforniaIrvine5200 Engineering HallCA 92617-2700USA Department of Mechanical Science and Engineering University of Illinois at Urbana-ChampaignUrbanaIL 61801USA Mechanical and Aerospace Engineering Department Case Western Reserve UniversityClevelandOH44106USA Department of Electrical and Computer Engineering University of Illinois at Urbana-ChampaignUrbanaIL61801USA Materials Research Laboratory University of Illinois at Urbana-ChampaignUrbanaIL61801USA International Institute for Carbon Neutral Energy Research(WPI-12CNER) Kyushu University744 Moto-okaNishi-kuFukuoka 819-0395Japan

Quantifying the nucleation processes involved in liquid-vapor phase-change phenomena,while dauntingly challenging,is central in designing energy conversion and thermal management *** technological advances in the deep learning and computer vision field offer the potential for quantifying such complex two-phase nucleation processes at unprecedented *** leveraging these new technologies,a multiple object tracking framework called“vision inspired online nuclei tracker(VISION-iT)”has been proposed to extract large-scale,physical features residing within boiling and condensation ***,extracting high-quality features that can be integrated with domain knowledge requires detailed discussions that may be field-or case-specific *** this regard,we present a demonstration and discussion of the detailed construction,algorithms,and optimization of individual modules to enable adaptation of the framework to custom *** concepts and procedures outlined in this study are transferable and can benefit broader audiences dealing with similar problems.

关键词： Deep learning Computer vision Nucleation Heat transfer Phase-change phenomena

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Liver abnormalities following SARS-CoV 2 infection in children 1 to 10 years of age

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Family Medicine and Community Health 2024年第1期12卷 28-35页

作者： Pauline Terebuh Veronica R Olaker Ellen K Kendall David C Kaelber Rong Xu Pamela b Davis Center for Artificial Intelligence in Drug Discovery Case Western Reserve UniversityClevelandOHUSA The Center for Clinical Informatics Research and Education The MetroHealth SystemClevelandOHUSA Department of Medicine PediatricsDepartment of Population and Quantitative Health SciencesCase Western Reserve UniversityClevelandOHUSA Center for Community Health Integration Case Western Reserve UniversityClevelandOHUSA

Objective beginning in October 2021 in the USA and elsewhere,cases of severe paediatric hepatitis of unknown aetiology were identified in young *** the adenovirus and adenovirus-associated virus have emerged as leading aetiological suspects,we attempted to investigate a potential role for SARS-CoV 2 in the development of subsequent liver *** We conducted a study using retrospective cohorts of deidentified,aggregated data from the electronic health records of over 100 million patients contributed by US healthcare *** Compared with propensity score matched children with other respiratory infections,children aged 1-10 years with COVID-19 had a higher risk of elevated transaminases(HR(95%CI)2.16(1.74 to 2.69))or total bilirubin(HR(95%CI)3.02(1.91 to 4.78)),or new diagnoses of liver diseases(HR(95%CI)1.67(1.21 to 2.30))from 1 to 6 months after *** with pre-existing liver abnormalities,liver abnormalities surrounding acute infection,younger age(1-4 years)or illness requiring hospitalisation all had similarly elevated *** who developed liver abnormalities following COVID-19 had more pre-existing conditions than those who developed abnormalities following other *** These results indicate that SARS-CoV 2 may prime the patient for subsequent development of liver infections or non-infectious liver *** rare(~1 in 1000),SARS-CoV 2 is a risk for subsequent abnormalities in liver function or the diagnosis of diseases of the liver.

关键词： elevated diagnosis subsequent

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ZmGns,a maize class I β-1,3-glucanase,is induced by biotic stresses and possesses strong antimicrobial activity

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Journal of Integrative Plant biology 2015年第3期57卷 271-283页

作者： Yu-Rong Xie Yenjit Raruang Zhi-Yuan Chen Robert L.brown Thomas E.cleveland Department of Plant Pathology and Crop Physiology Louisiana State University Agricultural Center biotechnology Research Institute the Chinese Academy of Agricultural Sciences Southern Regional Research Center USDA-ARS

Plant b-1,3-glucanases are members of the pathogenesis-related protein 2（PR-2） family,which is one of the 17 PR protein families and plays important roles in biotic and abiotic stress *** of the differentially expressed proteins（spot 842） identified in a recent proteomic comparison between five pairs of closely related maize（Zea mays L.） lines differing in aflatoxin resistance was further investigated in the present ***,the corresponding cDNA was cloned from maize and designated as *** encodes a protein of338 amino acids containing a potential signal *** expression of Zm Gns was detectible in all tissues studied with the highest level in *** was significantly induced by biotic stresses including three bacteria and the fungus Aspergillus *** was also induced by most abiotic stresses tested and growth hormones including salicylic *** vivo,ZmGns showed a significant inhibitory activity against thebacterial pathogen Pseudomonas syringae *** DC3000 and fungal pathogen botrytis cinerea when it overexpressed in *** high level of expression in the silk tissue and its induced expression by phytohormone treatment,as well as by bacterial and fungal infections,suggest it plays a complex role in maize growth,development,and defense.

关键词： β-1 3-Glucanase biological activity expression profiles Zea mays ZmGns

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Diagnostic delay in inflammatory bowel diseases in a German population

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World Journal of Gastroenterology 2024年第29期30卷 3465-3478页

作者： Elisabeth blüthner Annalena Dehe Carsten büning britta Siegmund Matthias Prager Jochen Maul Alexander Krannich Jan Preiß bertram Wiedenmann Florian Rieder Raneem Khedraki Frank Tacke Andreas Sturm Anja Schirbel Department of Hepatology and Gastroenterology Campus Virchow-Klinikum and Campus CharitéMitteCharité-Universitätsmedizin BerlinBerlin 10117Germany Department of Gastroenterology Vivantes Klinikum im FriedrichshainBerlin 10249Germany Department of Internal Medicine Krankenhaus WaldfriedeBerlin 14163Germany Department of Gastroenterology Infectious Diseases and RheumatologyCharité-Universitätsmedizin BerlinBerlin 12203Germany Praxis für Gastroenterologie berlin Zehlendorf Berlin 14195Germany Gastroenterologie am bayrischen Platz Berlin 10825Germany Clinical Trial Office Charité-Universitätsmedizin BerlinBerlin 10117Germany Department of Gastroenterology Diabetology and HepatologyVivantes Klinikum NeuköllnBerlin 10117Germany Department of Gastroenterology Hepatology and NutritionDigestive Diseases and Surgery InstituteThe Cleveland Clinic FoundationClevelandOH 44195United States Department of Internal Medicine DRK Kliniken Berlin WestendBerlin 14050Germany Gastroenterologie im Havelland Straße der EinheitFalkensee 14612Germany

bACKGROUND Early diagnosis is key to prevent bowel damage in inflammatory bowel disease(IbD).Risk factor analyses linked with delayed diagnosis in European IbD patients are scarce and no data in German IbD patients *** To identify risk factors leading to prolonged diagnostic time in a German IbD *** between 2012 and 2022,430 IbD patients from four berlin hospitals were enrolled in a prospective study and asked to complete a 16-item questionnaire to determine features of the path leading to IbD *** diagnostic time was defined as the time from symptom onset to consulting a physician(patient waiting time)and from first consultation to IbD diagnosis(physician diagnostic time).Univariate and multivariate analyses were performed to identify risk factors for each time *** The total diagnostic time was significantly longer in Crohn’s disease(CD)compared to ulcerative colitis(UC)patients(12.0 vs 4.0 mo;Pbetter outcome in these patients.

关键词： Diagnostic time Diagnostic delay Crohn’s disease Ulcerative colitis Germany

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Mapping and characterization of two relevance networks from SNP and gene levels

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Progress in Natural Science:Materials International 2009年第5期19卷 653-657页

作者： Wei Jiang a,1, Lijie Zhang b,1, bo Na a, Lihong Wanga, Jiankai Xu a, Xia Li a,b,c, Yadong Wangb, Shaoqi Rao da College of bioinformatics Science and Technology and bio-pharmaceutical Key Laboratory of Heilongjiang Province, Harbin Medical University, Harbin 150081, China b Department of Mathematics and Computer Science, Harbin Institute of Technology, Harbin 150080, China c Department of bioinformatics, Capital University of Medical Sciences, beijing 100084, China d Department of Cardiovascular Medicine and Molecular Cardiology, The cleveland Clinic Foundation, 9600 Euclid Avenue, cleveland, OH 44195, USA College of bioinformatics Science and Technology and bio-pharmaceutical Key Laboratory of Heilongjiang Province Harbin Medical University Harbin 150081 China Department of Mathematics and Computer Science Harbin Institute of Technology Harbin 150080 China Department of bioinformatics Capital University of Medical Sciences Beijing 100084 China Department of Cardiovascular Medicine and Molecular Cardiology The Cleveland Clinic Foundation 9600 Euclid Avenue Cleveland OH 44195 USA

Variations of gene expression and DNA sequence are genetically associated. The goal of this study was to build genetic networks to map from SNPs to gene expressions and to characterize the two different kinds of networks. We employed mutual information to evaluate the strength of SNP-SNP and gene-gene associations based on SNPs identity by descent (IbD) data and differences of gene expressions. We applied the approach to one dataset of Genetics of Gene Expression in Humans, and discovered that both the SNP relevance network and the gene relevance network approximated the scale-free topology. We also found that 12.09% of SNP-SNP interactions matched 24.49% of gene-gene interactions, which was consistent with that of the previous studies. Finally, we identified 49 hub SNPs and 115 hub genes in their relevance networks, in which 27 hub SNPs were associated with 25 hub genes.

关键词： SNP relevance network Gene relevance network Network mapping Network topology

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Composition Operators on a banach Space of Analytic Functions

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Acta Mathematica Sinica,English Series 1998年第2期14卷 201-208页

作者： Cao Guangfu (Department of Mathematics,Sichuan University,Chengdu 610064,China)N.Elias (6611 Tauglewood Court 3b,Hammond,IN46323)P.Ghatage (Department of Mathematics,cleveland State University,cleveland,OH44115)Yu Dahai (Department of Mathematics,Sichuan University,Chengdu 610064,China) Department of Mathematics Sichuan University 610064 Chengdu China

In this paper,we study composition operators on a banach space of analytic functions, denoted by X,which includes the bloch *** space arises naturally as the dual space of analytic functions in the bergman space L_a^1(D)which admit an atomic *** charac- terize the functions which induce compact composition operators and those which induce Fredholm operatorson this *** also investigate when a composition operator has a closed range.

关键词： bergman space Composition operator Compact operator Fredholm operator

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Integrated Principles of Zoology 11th ed.

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2001年

作者： cleveland P. Hickman Roberts Larson

来源：畅想之星图书光盘版（南... 评论

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Decision-Making and Management of Self-Care in Persons with Traumatic Spinal Cord Injuries: A Preliminary Study

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Journal of behavioral and brain Science 2024年第2期14卷 47-63页

作者： Paul E. Plonski Jasmin Vassileva Ryan Shahidi Paul b. Perrin William Carter Lance L. Goetz Amber brochetti James M. bjork Institute for Drug and Alcohol Studies Virginia Commonwealth University Richmond VA USA Richmond Veterans Affairs Medical Center Richmond VA USA Department of Psychiatry Virginia Commonwealth University Richmond VA USA Department of Psychology Virginia Commonwealth University Richmond VA USA Department of Physical Medicine and Rehabilitation Virginia Commonwealth University Richmond VA USA Department of Spinal Cord Injury Cleveland Veterans Affairs Medical Center Cleveland OH USA Department of Pharmacology and Toxicology Virginia Commonwealth University Richmond VA USA

Patients and physicians understand the importance of self-care following spinal cord injury (SCI), yet many individuals with SCI do not adhere to recommended self-care activities despite logistical supports. Neurobehavioral determinants of SCI self-care behavior, such as impulsivity, are not widely studied, yet understanding them could inform efforts to improve SCI self-care. We explored associations between impulsivity and self-care in an observational study of 35 US adults age 18 - 50 who had traumatic SCI with paraplegia at least six months before assessment. The primary outcome measure was self-reported self-care. In LASSO regression models that included all neurobehavioral measures and demographics as predictors of self-care, dispositional measures of greater impulsivity (negative urgency, lack of premeditation, lack of perseverance), and reduced mindfulness were associated with reduced self-care. Outcome (magnitude) sensitivity, a latent decision-making parameter derived from computationally modeling successive choices in a gambling task, was also associated with self-care behavior. These results are preliminary;more research is needed to demonstrate the utility of these findings in clinical settings. Information about associations between impulsivity and poor self-care in people with SCI could guide the development of interventions to improve SCI self-care and help patients with elevated risks related to self-care and secondary health conditions.

关键词： Spinal Cord Injury Self-Care Decision-Making Paraplegia Impulsive behavior Health Care

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