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Dermal Toxicity of Paraphenylenediamine

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biomedical and Environmental Sciences 1992年第4期5卷 321-324页

作者： A.K.MATHUR b.n.gupta S.SInGH A.SInGH S.nARAnG Industrial Toxicology Research Centre P.B. 80 Mahatama Gandhi MargIndustrial Toxicology Research Centre P.B. 80 Mahatama Gandhi MargIndustrial Toxicology Research Centre P.B. 80 Mahatama Gandhi MargIndustrial Toxicology Research Centre P.B. 80 Mahatama Gandhi MargIndustrial Toxicology Research Centre P.B. 80 Mahatama Gandhi Marg Lucknow 226001 IndiaLucknow 226001 IndiaLucknow 226001 IndiaLucknow 226001 IndiaLucknow 226001 India

The guinea pigs were dermally exposed to paraphenylenediamine (PPD) and in presence of an oxidising agent hydrogen peroxide for 15 and 30 d to assess their effects on some enzymes, lipid peroxidation and histamine contents in the skin. The activities of acid and alkaline phosphatases, β-glucuronidase, gamma glutamyl transpeptidase, histidase and tyrosinase were enhanced after application of either PPD or PPD plus hydrogen peroxide. The lipid peroxidation and histamine contents also showed marked elevation following exposure to the chemicals.

关键词： PPD Dermal Toxicity of Paraphenylenediamine

印度水(瘤)牛用尿素糖蜜矿物质复合舐块研究进展

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畜牧兽医科技 1992年第1期 41-42页

作者： b.n.gupta 董用威

印度一项反刍动物营养研究表明,水(瘤)牛以秸秆为主并饲以尿素、糖蜜、矿物质作为添加剂,极有利于增加秸秆消化率及其随意采食量。但是,由于某些限制因素,诸如糖蜜不易获得,和由于这些添加剂是现拌现用,农民日复一日地将这种添加剂喷洒... 详细信息

印度一项反刍动物营养研究表明,水(瘤)牛以秸秆为主并饲以尿素、糖蜜、矿物质作为添加剂,极有利于增加秸秆消化率及其随意采食量。但是,由于某些限制因素,诸如糖蜜不易获得,和由于这些添加剂是现拌现用,农民日复一日地将这种添加剂喷洒在秸秆上,很费劳力,在印度农村条件下有碍人们使用这项有用的技术。围绕上述问题,最近阿南德(Anand)

关键词：印度水牛尿素糖蜜矿物质营养

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用于35mm电影放映机的一种新型镜头

应用光学 1991年第3期12卷 16-20页

作者： ManojK.Mittal b.n.gupta K.D.Sharma 谢富能

由7个非胶合元件组成的一种新型镜头系统已经研制出来。这种新型镜头的焦距为75mm,相对孔径为 f/1.4,用于35mm 电影放映机的物镜上。为了比较该镜头系统的性能,以双高斯型镜头为基础,采用通常的设计方法,研制了一种由7个非胶合元件组成... 详细信息

由7个非胶合元件组成的一种新型镜头系统已经研制出来。这种新型镜头的焦距为75mm,相对孔径为 f/1.4,用于35mm 电影放映机的物镜上。为了比较该镜头系统的性能,以双高斯型镜头为基础,采用通常的设计方法,研制了一种由7个非胶合元件组成的系统。这种镜头的性能通过绘制象差曲线、能量分布曲线和几何 MTF 曲线进行了评定。这种新型镜头的性能优于目前使用的双高斯型镜头。

关键词：电影放映机镜头

A Comprehensive Survey on Federated Learning Applications in Computational Mental Healthcare

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Computer Modeling in Engineering & Sciences 2025年第1期142卷 49-90页

作者： Vajratiya Vajrobol Geetika Jain Saxena Amit Pundir Sanjeev Singh Akshat Gaurav Savi bansal Razaz Waheeb Attar Mosiur Rahman brij b.gupta Institute of Informatics and Communication University of DelhiDelhi110021India Maharaja Agrasen College University of DelhiDelhi110096India Computer Engineering Ronin InstituteMontclairNJ 07043USA Department of Research and Innovation Insights2TechinfoJaipur302001India University Centre for Research and Development(UCRD) Chandigarh UniversityChandigarh140413India Management Department College of Business AdministrationPrincess Nourah bint Abdulrahman UniversityRiyadh11671Saudi Arabia CCRI&Department of Computer Science and Information Engineering Asia UniversityTaichung413Taiwan Symbiosis Centre for Information Technology(SCIT) Symbiosis International UniversityPune411057India Center for Interdisciplinary Research University of Petroleum and Energy Studies(UPES)Dehradun248007India

Mental health is a significant issue worldwide,and the utilization of technology to assist mental health has seen a growing *** aims to alleviate the workload on healthcare professionals and aid *** applications have been developed to support the challenges in intelligent healthcare ***,because mental health data is sensitive,privacy concerns have *** learning has gotten some *** research reviews the studies on federated learning and mental health related to solving the issue of intelligent healthcare *** explores various dimensions of federated learning in mental health,such as datasets(their types and sources),applications categorized based on mental health symptoms,federated mental health frameworks,federated machine learning,federated deep learning,and the benefits of federated learning in mental health *** research conducts surveys to evaluate the current state of mental health applications,mainly focusing on the role of Federated Learning(FL)and related privacy and data security *** survey provides valuable insights into how these applications are emerging and evolving,specifically emphasizing FL’s impact.

关键词： Depression emotional recognition intelligent healthcare systems mental health federated learning stress detection sleep behaviour

Influence of Various Parameters on Collapse behaviour of Thin Cylinders

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上海交通大学学报 2004年第z2期38卷 1-7页

作者： n K gupta Applied Mechanics Department ⅡT Delhi India - 110016

Axial compression experiments on as received aluminum tubes and tubes with wall thickness eccentricity incorporated by off centre machining showed that the eccentricity caused transition of their collapse mode from axisymmetric to diamond. The numerical simulation of the collapse phenomenon was undertaken using a static non-linear Finite Element Analysis in AnSYS, and results are found to compare well with the experimental load compression and energy absorption responses for axisymmetric concertina and non-axisymmetric diamond modes. Having validated the numerical model with experiments, it has been used to undertake a systematic study of the load - compression characteristics and collapse mode transitions of the tubes with varying eccentricities in wall thickness and boundary conditions, as well as the material properties.

关键词： thin tube collapse thickness eccentricity AnSYS axial compression

Intricacies during pregnancy with gestational diabetes mellitus

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World Journal of Clinical Cases 2025年第1期13卷 62-64页

作者： Richa Rattan Rimesh Pal Parul Chawla gupta Arvind Kumar Morya Ripunjay Prasad Department of Endocrinology Post Graduate Institute of Medical Education and ResearchChandigarh 160012India Department of Ophthalmology Post Graduate Institute of Medical Education and ResearchChandigarh 160012PunjabIndia Department of Ophthalmology All India Institute of Medical SciencesHyderabad 508126TelanganaIndia Department of Ophthalmology RP Eye InstituteDelhi 110001India

The study by Cao et al aimed to identify early second-trimester biomarkers that could predict gestational diabetes mellitus(GDM)development using advanced proteomic techniques,such as Isobaric tags for relative and absolute quantitation isobaric tags for relative and absolute quantitation and liquid chromatography-mass spectrometry liquid chromatography-mass *** analysis revealed 47 differentially expressed proteins in the GDM group,with retinol-binding protein 4 and angiopoietin-like 8 showing significantly elevated serum levels compared to *** these findings are promising,the study is limited by its small sample size(n=4 per group)and lacks essential details on the reproducibility and reliability of the protein quantification methods ***,the absence of experimental validation weakens the interpretation of the protein-protein interaction network identified through bioinformatics *** study's focus on second-trimester biomarkers raises concerns about whether this is a sufficiently early period to implement preventive interventions for *** GDM risk during the first trimester or pre-conceptional period may offer more clinical *** its limitations,the study presents valuable insights into potential GDM biomarkers,but larger,well-validated studies are needed to establish their predictive utility and generalizability.

关键词： Gestational diabetes mellitus biomarkers Differentially expressed proteins Retinol-binding protein 4 Angiopoietin-like 8 Proteomics Lifestyle interventions Early prediction

nano-Enhanced Dairy Scum biodiesel blends:Unleashing the Power of Aluminium Oxide for Sustainable and Efficient Engine Performance

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Journal of Thermal Science 2025年第1期 283-302页

作者： Veeranna MODI Prasad b.RAMPURE Sunil Kumar SHETTY Madeva nAGARAL Channa Keshava nAIK n Johar MGM Muhammad Irsyad AbDULLAH Abdullah I.AL-MAnSOUR Shamshad ALAM KLE College of Engineering and Technology ChikodiVisvesvaraya Technological University nitte (Deemed to be University) NMAM Institute of Technology (NMAMIT)Department of Mechanical Engineering Aircraft Research and Design Centre HAL Department of Mechanical Engineering BGS College of Engineering and TechnologyBengaluruAffiliated to Visvesvaraya Technological University Management and Science University Department of Civil Engineering College of EngineeringKing Saud University

This study investigates the effect of aluminium oxide nanoparticlesaddition to biodiesel blends made from dairy milk scum on performance and combustion characteristics of the diesel *** dispersion of Al2O3nanoparticles in b20 blends at different concentrations was done with the help of *** number of blends were prepared for the *** Machine learning algorithms(Random Forest（RF）and Catboost) was used for the *** results show that in comparison to biodiesel blends without nanoparticles,the kinematic viscosity and density is higher for fuel blends with *** these Fuel blends have higher calorific *** blends exhibited reduced brake Specific Fuel Consumption（bSFC） of2.85% than the blends without nano particles(Dairy Scum Methyl Ester biodiesel 20%+neat Diesel 80%（in volume）,DSMEb20),57.14% less CO,40.8% less hydrocarbon,and increased nOxemissions compared to conventional diesel,contributing to the development of environmentally friendly and renewable biofuel blends with *** b20nP30 is the optimal blend for performance and emission *** study concludes with findings on enhanced brake Thermal Efficiency（bTE） of 26.29% in 3×10-5（in volume） Al2O3nanoparticle-blended DSME b20 and other DSME b20 fuel blends,emphasizing the importance of optimal nanoparticle *** correlation matrix shows how engine load,efficiency measures（bTE,bSFC）,and emissions（CO,CO2,nOx,Smoke） are connected in complex *** results help us understand the complicated dynamics of engine performance and emission characteristics ***'s diagram for bTE and bSFC shows that Catboost-based bTE models perform superior to RF-based models during the training as well as testing *** results were obtained for CO and CO2emission results.

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Impacts of PI3K/protein kinase b pathway activation in reactive astrocytes: from detrimental effects to protective functions

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neural Regeneration Research 2025年第4期20卷 1031-1041页

作者： Ramón Pérez-núñez María Fernanda González Ana María Avalos Lisette Leyton Cellular Communication Laboratory Programa de Biología Celular y MolecularCenter for Studies on ExerciseMetabolism and Cancer(CEMC)Instituto de Ciencias Biomédicas(ICBM)Facultad de MedicinaUniversidad de ChileSantiagoChile Advanced Center for Chronic Diseases(ACCDiS) Faculty of Chemical and Pharmaceutical Sciences&Faculty of MedicineUniversidad de ChileSantiagoChile Instituto de Ciencias biomédicas Facultad de Ciencias de la SaludUniversidad Autónoma de ChileSantiagoChile

Astrocytes are the most abundant type of glial cell in the central nervous *** injury and inflammation,astrocytes become reactive and undergo morphological and functional *** on their phenotypic classification as A1 or A2,reactive astrocytes contribute to both neurotoxic and neuroprotective responses,***,this binary classification does not fully capture the diversity of astrocyte responses observed across different diseases and *** analysis has revealed that reactive astrocytes have a complex landscape of gene expression profiles,which emphasizes the heterogeneous nature of their *** actively participate in regulating central nervous system inflammation by interacting with microglia and other cell types,releasing cytokines,and influencing the immune *** phosphoinositide 3-kinase(PI3K)/protein kinase b(AKT)signaling pathway is a central player in astrocyte reactivity and impacts various aspects of astrocyte behavior,as evidenced by in silico,in vitro,and in vivo *** astrocytes,inflammatory cues trigger a cascade of molecular events,where nuclear factor-κb serves as a central mediator of the pro-inflammatory ***,we review the heterogeneity of reactive astrocytes and the molecular mechanisms underlying their *** highlight the involvement of various signaling pathways that regulate astrocyte reactivity,including the PI3K/AKT/mammalian target of rapamycin(mTOR),αvβ3 integrin/PI3K/AKT/connexin 43,and notch/PI3K/AKT *** targeting the inactivation of the PI3K/AKT cellular signaling pathway to control reactive astrocytes and prevent central nervous system damage,evidence suggests that activating this pathway could also yield beneficial *** dual function of the PI3K/AKT pathway underscores its complexity in astrocyte reactivity and brain function *** review emphasizes the importance of employing astrocyte-exclusive models to underst

关键词： inflammation integrins neuroprotective neurotoxic phosphatidylinositol 3-kinase reactive astrocytes signal transduction Thy-1(CD90)

Motion of a permeable shell in a spherical container filled with non-newtonian fluid

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Applied Mathematics and Mechanics(English Edition) 2017年第12期38卷 1697-1708页

作者： V.MISHRA b.R.gupta Department of Mathematics Jaypee University of Engineering and TechnologyMadhya Pradesh 473226India

This paper presents an analytical study of creeping motion of a permeable sphere in a spherical container filled with a micro-polar fluid. The drag experienced by the permeable sphere when it passes through the center of the spherical container is studied. Stream function solutions for the flow fields are obtained in terms of modified bessel functions and Gegenbauer functions. The pressure fields, the micro-rotation components, the drag experienced by a permeable sphere, the wall correction factor, and the flow rate through the permeable surface are obtained for the frictionless impermeable spherical container and the zero shear stress at the impermeable spherical container. Variations of the drag force and the wall correction factor with respect to different fluid parameters are studied. It is observed that the drag force, the wall correction factor, and the flow rate are greater for the frictionless impermeable spherical container than the zero shear stress at the impermeable spherical container. Several cases of interest are deduced from the present analysis.

关键词： micro-polar fluid permeable sphere Darcy law stream function drag force wall correction factor spherical container