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morphophysiological Diversity and Haplotype Analysis of Saltol QTL Region in Diverse Rice Landraces for Salinity Tolerance

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Rice science 2023年第4期30卷 306-320,I0010-I0012页

作者： b.m.lokeshkumar S.L.KRISHNAmURTHY Suman RATHOR Arvinder Singh WARRIACH N.m.VINAYKUmAR b.m.DUSHYANTHAKUmAR Parbodh Chander SHARmA Division of Crop Improvement Central Soil Salinity Research InstituteKarnal-132001HaryanaIndia Department of biotechnology Kuvempu UniversityShankaraghattaShimvamogga-577451KarnatakaIndia Department of Genetics and Plant breeding University of Agricultural and Horticultural ScienceShimvamogga-577204KarnatakaIndia

Rice is sensitive to salinity stress at both the seedling and reproductive *** present study used 145 rice genotypes comprising of 100 landraces and 45 advanced breeding lines collected from different regions of *** genotypes were evaluated in hydroponics under control[electrical conductivity(ECe)~1.2 dS/m]and saline(ECe~10.0 dS/m)environments along with susceptible(IR29)and tolerant(FL478)*** stress susceptibility index for eight morphophysiological traits was *** of variance showed significant differences among the genotypes for all the parameters studied in control,stress and relative stress *** identified 3 landraces(Kuttimanja,Tulasimog and IET-13713I)as tolerant and 14 lines as moderately tolerant to salt *** correlations in the morphological(root and shoot lengths)and physiological traits(shoot Na^(+),Ca^(2+)and mg^(2+)contents,and Na^(+)/K^(+)ratio)were observed under all the *** hierarchical cluster analysis grouped the genotypes into five clusters,among which cluster Ⅱ comprised salt-tolerant *** of Saltol region using 11 simple sequence repeat markers on 17 saline tolerant and moderately tolerant lines was *** AP3206F,Rm10793 and Rm3412b,located close to SKC1 gene(11.23‒12.55 mb),displayed diverse allelic variations and they were not related to the FL478 *** this region,tolerant lines like Kuttimanja,IET-13713I and Tulasimog have new *** a result,these lines may be suitable candidates for novel genomic regions governing rice salinity ***-tolerance ability of Kuttimanja,Tulasimog and IET-13713I was validated in two years in three salinity stress *** promising lines can be used in breeding programs to broaden the genetic base of salinity tolerance in rice,and it may help to dissect key genomic regions responsible for salinity tolerance.

关键词： haplotype salinity tolerance rice Saltol diversity SKC1 gene

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Neuroinflammation revisited through the microglial lens

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Neural Regeneration Research 2025年第7期20卷 1989-1990页

作者： Renato Socodato João b.Relvas Institute of Research and Innovation in Health(i3S)and Institute for molecular and Cell biology(IbmC) University of PortoPortoPortugal Department of biomedicine Faculty of Medicine of the University of Porto(FMUP)PortoPortugal

Neuroimmunology is emerging as a pivotal field,shedding light on the intricate dialogues between the central nervous system(CNS)and the immune *** exploration is particularly significant in understanding microglia,the CNS’s innate immune cells,beyond the conventional conflation of“neuroinflammation”and“microglial activation.”This conflation has clouded the true complexity of these processes,potentially stalling scientific progress and the development of new *** challenge the long-standing perspectives that have oversimplified these interactions,advocating for a deeper exploration of the dynamic relationship between neuroinflammation and microglial *** dissecting specific molecular pathways,we aim to illuminate their elaborate roles in neuroinflammatory responses,especially in the context of Alzheimer’s disease(AD).Here,neuroinflammation is not merely a passive observer or a direct antagonist but a complex agent in the disease’s *** article calls for a significant paradigm shift towards an integrative,multi-omics approach to *** such a comprehensive framework is crucial for advancing our understanding of neuroinflammatory conditions and paving the way for targeted therapeutic strategies for brain diseases.

关键词： inflammation simplified activation

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Distribution and geochemical significance of dibenzofurans,phenyldibenzofurans and benzo[b]naphthofurans in source rock extracts from Niger Delta basin,Nigeria

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Acta Geochimica 2020年第6期39卷 973-987页

作者： Abiodun b.Ogbesejana Oluwasesan m.bello Department of Applied Chemistry Federal University Dutsin-MaP.M.B.5001Dutsin-MaKatsina StateNigeria

The distribution and geochemical significance of dibenzofurans,phenyldibenzofurans and benzo[b]naptho-furans in source rocks from Niger Delta basin,Nigeria,were investigated by Rock-Eval pyrolysis and gas chro-matography--mass spectrometry(GC--mS).The data obtained from the source rocks evaluation showed that the rock samples contained type 1/III kerogen capable of generating oil and gas and were within immature to early mature *** relative abundance of the Cor,C1-and C2-dibenzofurans range from 1.75%to 29.82%,27.60%to 40.52%and 29.66%to 6889%,*** diben-zofurans were dominated by *** the C1-dibenzofurans,2-+3-methyldibenzofuran was the most abundant in the rock samples while 1-methy ldibenzofuran appeared to be the *** relative abundance of benzo[b]naphtho[1,2-d]furan(1,2]bNF),benzo[b]naph-tha[2,1-d]furan(2.1]bNF)and benzo[b]naphtha[2,3-d]fu-ran([2.3]bNF)in the rock extracts range from 12.01%to 52.58%,32.61%to 75.219%and 10.27%to 52.43%.The wide range of values recorded for the three isomers of benzo[b lnapthofurans in the samples suggest source rocks formed from mixed organic *** the pheny ldibenzofuran isomers,4-pheny ldibenzofuran was the most abundant while 1-phenyldibenzofuran was the *** ratio-1(PhFR-1)and pheny ldibenzofuran ratio-2(PhFR-2)values range from 0.13 to 1.20 and 0.11 to 2.11,*** resuls showed that the relative abundance of PhFR-1 and PhFR-2 increase gradually with increasing burial depth and maturity(VRo≤0.77%,mPI-1≤*** s 443℃),and have a good correlations with calculated vitrinite ***-I and maximum Temperature(Tmax)-This range of values suggested immature to early mature source *** source rocks were found to have shale and coul lithologics and deposited in a lacustrine/fuvial deltaic settings within immature to early mature stages based on the distribution of dibenzofurans,pheny ldiben-zofurans and benzo[b]naphthofurans in the source rock

关键词： Dibenzofurans benzo[b]napthofurans Source rocks Niger delta Gas chromatography-mass spectrometry

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mitochondria–cGAS–STING axis is a potential therapeutic target for senescence-dependent inflammaging-associated neurodegeneration

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Neural Regeneration Research 2025年第3期20卷 805-807页

作者： Josém.Izquierdo Centro de biología molecular Severo Ochoa(Cbm) Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid(CSIC-UAM)MadridSpain

The word “senescence” comes from the Latin senescens, meaning “to begin to age”, and is characterized by a long-lasting but reversible block in proliferation, resulting from stress-induced cell cycle arrest of pre... 详细信息

关键词： Latin potential lasting

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Synthesis, spectroscopic characterization, and thermal decomposition kinetics of some lanthanide(III) nitrate complexes of 2-(N-o-hydroxyacetophenone) amino-3-carboxyethyl-4,5,6,7-tetrahydrobenzo[b]thiophene

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Journal of Rare Earths 2008年第4期26卷 463-468页

作者： K. mohanan m. Thankamony b. Sindhu Kumari Department of Chemistry University of Kerala Kariavattom Campus Trivandrum-695 581. Kerala India

Complexes of La（Ⅲ）, Ce（Ⅲ）, Pr（Ⅲ）, Nd（Ⅲ）, Sm（Ⅲ）, Eu（Ⅲ）, Gd（Ⅲ）, Dy（Ⅲ）, Yb（Ⅲ）, and Lu0ID with 2-（N-o- hydroxyacetophenone）amino-3-carboxyethyl-4,5,6,7-tetrahydrobenzo[b]thiophene （HAAT） formed by the condensation of o-hydroxyacetophenone and 2-amino-3-carboxyethyl-4,5,6,7-tetrahydrobenzo[b]thiophene were synthesized and characterized on the basis of elemental analyses, molar conductance measurements, magnetic susceptibility data, UV-Visible, IR, and NmR spectral studies. The spectral data revealed that the ligand acted as a neutral tridentate coordinating to the metal ion through ONO donor sequence. A coordination number nine was proposed for the complexes. Thermal decomposition studies of the ligand and lanthanum（Ⅲ） complex were carried out and kinetic parameters were calculated using Coats-Redfem equation. The decomposition reactions followed random nucleation mechanism with one nucleus on each particle.

关键词： lanthanides o-hydroxyacetophenone molar conductance magnetic susceptibility thermal study rare earths

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Estimation of radiative capture^(13)b(n,γ0+1)^(14)b reaction rate in the modified potential cluster model

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Chinese Physics C 2023年第10期47卷 130-142页

作者： A.S.Tkachenko N.A.burkova b.m.Yeleusheva S.b.Dubovichenko Fesenkov Astrophysical Institute 050020AlmatyKazakhstan al-Farabi Kazakh National University 050040AlmatyKazakhstan

We discuss current attempts to employ the modified potential cluster model to describe the available experimental data on the^(13)b(n,γ0+1)^(14)b total *** estimated results of the m1 and E1 transitions from the n^(13)b scattering states to the ground and first excited states of^(14)b are *** 1st resonance at Ex=1.275 meV(1+)is revealed in both the cross-section and reaction *** the variation in the asymptotic constant,a thermal cross-section interval of 5.1-8.9 mb is *** on the theoretical total cross-sections at energies of 0.01 eV to 5 meV,we calculate the reaction rate in the temperature range of 0.01 to *** ignition T9 values of the^(13)b(n,γ0+1)^(14)b reaction depending on a neutron number density n_(n)of~10^(22)cm^(−3)are *** radiative neutron capture reaction rates on the boron^(10-13)b and carbon^(12-14)Сisotopes are compared.

关键词： radiative neutron capture ^(14)b nucleus total cross-sections reaction rate potential cluster model r-process

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Association of the glycemic background patterns and the diabetes management efficacy in poorly controlled type 2 diabetes

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World Journal of Diabetes 2025年第1期16卷 74-90页

作者： Ayşe N Erbakan müzeyyen Arslan bahadır FatoşN Kaya büşra Güleç miraçVural Keskinler Ümmügülsüm AktemurÇelik Özge Faydalıel banu mesçi Aytekin Oğuz Department of Internal medicine Prof Dr Suleyman Yalcin City HospitalIstanbul Medeniyet UniversityIstanbul 34722Türkiye Department of Family medicine Istanbul Medeniyet UniversityIstanbul 34722Türkiye

bACKGROUND Inadequate glycemic control in patients with type 2 diabetes(T2Dm)is a major public health problem and a significant risk factor for the progression of diabetic *** To evaluate the effects of intensive and supportive glycemic management strategies over a 12-month period in individuals with T2Dm with glycated hemoglobin(HbA1c)≥10%and varying backgrounds of glycemic *** This prospective observational study investigated glycemic control in patients with poorly controlled T2Dm over 12 *** were categorized into four groups based on prior glycemic history:Newly diagnosed,previously well controlled with recent worsening,previously off-target but now worsening,and HbA1c consistently above 10%.HbA1c levels were monitored quarterly,and patients received medical,educational,and dietary support as *** analysis focused on the success rates of good glycemic control and the associated factors within each *** The study showed significant improvements in HbA1c levels in all *** most significant improvement was observed in individuals newly diagnosed with diabetes:65%achieved an HbA1c target of≤7%.The results varied between participants with different glycemic control histories,followed by decreasing success rates:39%in participants with previously good glycemic control,21%in participants whose glycemic control had deteriorated compared to before,and only 10%in participants with persistently poor control,with mean HbA1c levels of 6.3%,7.7%,8.2%,and 9.7%,*** one year,65.2%of the“newly diagnosed patients”,39.3%in the“previously controlled group”,21.9%in the“previously off-target but now worsened'”group and 10%in the“poorly controlled from the start”group had achieved HbA1c levels of 7 and *** In poorly controlled diabetes,the rate at which treatment goals are achieved is associated with the glycemic background characteristics,emphasizing the need for tailored ***

关键词： Type 2 diabetes mellitus Glycated hemoglobin Glycemic control Patient-centered care Diabetes management glycemic background

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Nonlinear three-dimensional stretched flow of an Oldroyd-b fluid with convective condition, thermal radiation, and mixed convection

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Applied mathematics and mechanics(English Edition) 2017年第7期38卷 969-980页

作者： b. mAHANTHESH b. J. GIREESHA S.A. SHEHZAD F.m. AbbASI R. S. R. GORLA Department of mathematics Christ University Bangalore 560029 Karnataka India Department of Studies and Research in mathematics Kuvempu University Shankarghatta 577451 Karnataka India Department of mathematics COMSATS Institute of Information Technology Sahiwal 57000 Pakistan Department of mathematics COMSATS Institute of Information Technology Islamabad 44000 Pakistan Department of mechanical and Civil Engineering Purdue University Northwest Indiana 46391 U. S. A

The effect of non-linear convection in a laminar three-dimensional Oldroyd-b fluid flow is addressed. The heat transfer phenomenon is explored by considering the non-linear thermal radiation and heat generation/absorption. The boundary layer as- sumptions are taken into account to govern the mathematical model of the flow analy- sis. Some suitable similarity variables are introduced to transform the partial differen- tial equations into ordinary differential systems. fifth-order techniques with the shooting method The Runge-Kutta-Fehlberg fourth- and are used to obtain the solutions of the dimensionless velocities and temperature. The effects of various physical parameters on the fluid velocities and temperature are plotted and examined. A comparison with the exact and homotopy perturbation solutions is made for the viscous fluid case, and an excellent match is noted. The numerical values of the wall shear stresses and the heat transfer rate at the wall are tabulated and investigated. The enhancement in the values of the Deborah number shows a reverse behavior on the liquid velocities. The results show that the temperature and the thermal boundary layer are reduced when the non- linear convection parameter increases. The values of the Nusselt number are higher in the non-linear radiation situation than those in the linear radiation situation.

关键词： nonlinear thermal convection nonlinear thermal radiation Oldroyd-b fluid,convective boundary condition heat source/sink

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Role of vitamin b12 deficiency in ischemic stroke risk and outcome

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Neural Regeneration Research 2021年第3期16卷 470-474页

作者： Gyllian b.Yahn Jamie E.Abato Nafisa m.Jadavji Department of biomedical Sciences Midwestern UniversityGlendaleAZUSA Department of Neuroscience Carleton UniversityOttawaONCanada

Currently,ischemic stroke is the most prevalent form of stroke compared to hemorrhagic and there is a high incidence in older *** is a modifiable risk factor for stroke.b-vitamins are part of a metabolic network that integrates nutritional signals with biosynthesis,redox homeostasis,and *** vitamins play an essential role in the regulation of cell proliferation,stress resistance,and embryo development.A deficiency in vitamin b12 is common in older adults and has been reported to be implicated in ischemic *** aim of this review was to investigate whether vitamin b12 deficiencies impact the risk and outcome of ischemic *** data from our literature review strongly suggest that a deficiency in vitamin b12 is a risk factor for ischemic stroke and possible *** survey of the literature has identified that there is a gap in the understanding of the mechanisms through which a vitamin b12 deficiency leads to an increased risk of stroke and outcome.A vitamin b12 deficiency can increase homocysteine levels,which are a well-established risk factor for ischemic *** potential mechanism through which vitamin b12 deficient may impact neurological function and increase risk of stroke,is changes in myelination,however this link requires further *** studies are required in model systems to understand how a vitamin b12 deficiency changes the brain.

关键词： b-vitamins ischemic stroke one-carbon vitamin b12

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On a biseparability criterion of bipartite qudit state

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Chinese Physics b 2019年第8期28卷 42-49页

作者： b benzimoun m Daoud LPHE-modeling and Simulation Faculty of SciencesUniversity Mohammed ⅤRabatMorocco Department of Physics Faculty of Sciences-Ain ChockUniversity Hassan ⅡCasablancaMorocco Abdus Salam International Centre for Theoretical Physics TriesteItaly

In this paper,we propose a new approach to tackle the separability problem for bipartite qudit *** is based on the majorana representation which allows to represent a N-spinors(qudit)as a symmetric state of N spin-1/*** also discuss how we can exploit such representation and the notion of the biseparability of multipartite qubit states in the sense to establish new criteria of the separability problem based on the PPT and concurrence.

关键词： separability bipartite qubit state partial separability majorana representation

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