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Effectiveness of biofertilizers foliar application on yield and quality traits of flax(Linum usitatissimum L.)

Oil Crop Science 2024年第2期9卷 91-101页

作者： Saied El Sayed A.b.bakry O.A.Nofal M.A.Abo Horish Plant Nutrition Department National Research Centre33 El-Behouth St12622DokkiCairoEgypt Field Crops Department National Research Centre33 El-Behouth St12622DokkiCairoEgypt

Flax is considered to be one of the most significant dual-purpose crops for oil and fiber production in Egypt and *** have a substantial impact on various metabolic processes,including increased photo-synthesis,endogenous hormone levels,ion absorption,nucleic acid synthesis,and protein *** factors collectively contribute to the growth and development of ***,this study aims to investigate how three biofertilizers(Algae extract,CMS as a by-product of yeast,and Metalosate multi minerals as amino acids)can enhance both the quantity and quality of flax seed yield under sandy soil *** field experiments were conducted at the Experimental Station of National Research Centre in Nubaria District,behira Governorate,Egypt during two seasons(2021/2022)using a randomized complete block design(RCbD).The results revealed significant differences among all tested biofertilizers in terms of various characteristics studied in *** application of algae extract at a rate of 1.50 mL/L resulted in an increase in seed yield(ton/ha)by 26.69%&19.89%,straw yield(ton/ha)by 8.08%&17.12%,and oil yield(kg/ha)by 47.72%&33.69%compared to the control group during both seasons *** applications of algae extract at a rate of 1.50 mL/L along with CMS at a rate of 5 m L/L and amino acids at a rate of 1.50 mL/L demonstrated significantly higher macronutrient contents(N,P,k),micronutrient contents(Fe,Zn,Mn),seed oil content,and protein content in flax seeds during both *** highest values for seed oil content and protein content%were obtained through foliar application of amino acids at a rate of 1.50 mL/*** can be concluded that foliar sprays with these bio-fertilizers effectively improved flax performance by increasing seed straw and oil yields,nutrients oil,protein and fatty acids seeds contents.

关键词： Flax bio fertilizers Seeds yield Nutrient contents Quality

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Small molecule conjugates with selective estrogen receptor β agonism promote anti-aging benefits in metabolism and skin recovery

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Acta Pharmaceutica Sinica b 2024年第5期14卷 2137-2152页

作者： Tarik Zahr Vijay k.boda Jian Ge Lexiang Yu Zhongzhi Wu Jianwen Que Wei Li Li Qiang Naomi berrie Diabetes Center Columbia UniversityNew YorkNY 10032USA Department of Molecular Pharmacology and Therapeutics Columbia UniversityNew YorkNY 10032USA Department of Pharmaceutical Sciences College of PharmacyUniversity of Tennessee Health Science CenterMemphisTN 38163USA Drug Discovery Center College of PharmacyUniversity of Tennessee Health Science CenterMemphisTN 38163USA Division of Digestive and Liver Diseases Columbia UniversityNew YorkNY 10032USA Center for Human Development Columbia UniversityNew YorkNY 10027USA Department of Pathology and Cell biology Columbia UniversityNew YorkNY 10032USA Department of Medicine Columbia UniversityNew YorkNY 10032USA

Estrogen is imperative to mammalian reproductivity,metabolism,and ***,the hormone activating estrogen receptor(ERs)αcan cause major safety concerns due to the enrichment of ERαin female tissues and certain *** contrast,ERβis more broadly expressed in metabolic tissues and the ***,it is desirable to generate selective ERβagonist conjugates for maximizing the therapeutic effects of ERs while minimizing the risks of ERα***,we report the design and production of small molecule conjugates containing selective non-steroid ERβagonists Gtx878 or *** of aged mice with our synthesized conjugates improved aging-associated declines in insulin sensitivity,visceral adipose integrity,skeletal muscle function,and skin health,with validation in *** further uncovered the benefits of ERβconjugates in the skin using two inducible skin injury mouse models,showing increased skin basal cell proliferation,epidermal thickness,and wound ***,our ERβ-selective agonist conjugates offer novel therapeutic potential to improve aging-associated conditions and aid in rejuvenating skin health.

关键词： Estrogen receptorβ Aging Metabolism Skin injury Muscle metabolism Small molecule conjugates Regeneration Adiposity

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Multi-aspect analysis of ureteral access sheath usage in retrograde intrarenal surgery: A RIRSearch group study

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Asian Journal of Urology 2024年第1期11卷 80-85页

作者： Oktay Özman Hacı M.Akgül Cem başataç Önder Çınar Eyüp b.Sancak Cenk M.Yazıcı bülent Önal Haluk Akpınar Gaziosmanpasa Training and Research Hospital Urology ClinicİstanbulTurkey TekirdağNamık kemal University School of MedicineDepartment of UrologyTekirdağTurkey Group Florence Nightingale Hospitals Department of UrologyİstanbulTurkey Zonguldak bulent Ecevit University School of MedicineDepartment of UrologyZonguldakTurkey Çanakkale Onsekiz Mart University School of MedicineDepartment of UrologyÇanakkaleTurkey İstanbul University-Cerrahpaşa Cerrahpaşa Medical FacultyDepartment of UrologyİstanbulTurkey

Objective:To evaluate the effect of ureteral access sheath(UAS)use and calibration change on stone-free rate and complications of retrograde intrarenal surgery(RIRS).Methods:Data from 568 patients undergoing RIRS for kidney or upper ureteral stones were retrospectively ***,patients were compared after 1:1 propensity score matching,according to UAS usage during RIRS(UAS used[+]87 and UAS non-used[−]87 patients).Then all UAS+patients(n=481)were subdivided according to UAS calibration:9.5-11.5 Fr,10-12 Fr,11-13 Fr,and 13-15 *** outcomes of the study were the success and complications of ***:Stone-free rate of UAS+patients(86.2%)was significantly higher than UAS−patients(70.1%)after propensity score matching(p=0.01).Stone-free rate increased with higher caliber UAS(9.5-11.5 Fr:66.7%;10-12 Fr:87.0%;11-13 Fr:90.6%;13-15 Fr:100%;pker UAS(17.2%)but was not statistically significant(p=0.09).UAS usage was an independent factor predicting stone-free status or peri-and post-operative complications(odds ratio[OR]3.654,95%confidence interval[CI]1.314-10.162;OR 4.443,95%CI 1.350-14.552;OR 4.107,95%CI 1.366-12.344,respectively).Conclusion:Use of UAS in RIRS may increase stone-free rates,which also increase with higher caliber *** usage may reduce complications;however,complications seemingly increase with higher UAS calibration.

关键词： Stone Retrograde intrarenal surgery Ureteral access sheath Urolithiasis kidney

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Magnetic field regression using artificial neural networks for cold atom experiments

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Chinese Physics b 2024年第2期33卷 46-51页

作者：陈子霆黃建陶 bojeong Seo 黄明琛 Mithilesh k.Parit 何逸飞甄浩廷 Jensen Li Gyu-boong Jo Department of Physics The Hong Kong University of Science and TechnologyKowloon 999077China

Accurately measuring magnetic fields is essential for magnetic-field sensitive experiments in areas like atomic,molecular,and optical physics,condensed matter experiments,and other ***,since many experiments are often conducted in an isolated environment that is inaccessible to experimentalists,it can be challenging to accurately determine the magnetic field at the target ***,we propose an efficient method for detecting magnetic fields with the assistance of an artificial neural network(NN).Instead of measuring the magnetic field directly at the desired location,we detect fields at several surrounding positions,and a trained NN can accurately predict the magnetic field at the target *** training,we achieve a below 0.3%relative prediction error of magnetic field magnitude at the center of the vacuum chamber,and successfully apply this method to our erbium quantum gas apparatus for accurate calibration of magnetic field and long-term monitoring of environmental stray magnetic *** demonstrated approach significantly simplifies the process of determining magnetic fields in isolated environments and can be applied to various research fields across a wide range of magnetic field magnitudes.

关键词： ultracold gases trapped gases measurement methods and instrumentation

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Investigating the Air Quality Parameters in Louisiana’s Industrial Corridor: A baton Rouge Case Study

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Journal of Geoscience and Environment Protection 2024年第7期12卷 139-164页

作者： Oluwafemi Awolesi Peter G. Oni Oluwatoyin k. Adekoya Seyi b. Adekoya Oluwafeyikemi D. Ogunmusi Fatemeh Ghafari Abosede Oje Odunayo Lawal Department of Environmental Sciences Louisiana State University Baton Rouge USA Department of Construction Management Louisiana State University Baton Rouge USA Department of Chemistry and biochemistry Worcester Polytechnic Institute Worcester USA Department of Water Resource Policy Grand Valley State University Grand Rapids USA Department of Chemistry and Chemical biology The University of New Mexico Albuquerque USA Department of Chemistry University of Louisiana Lafayette USA Research & Development Unit Ecoxygiene Services Limited Lagos Nigeria

In a local context, sustainable development entails utilizing the current resources—material and immaterial, measurable and immeasurable, popular and unpopular—of the community in a manner that avoids overexploitation and ensures intergenerational equity. This approach prioritizes the safety and health of local citizens, placing communal productivity above corporate profitability. This research aims to assess air quality surrounding 28 chemical industry sites in baton Rouge, Louisiana, to understand the environmental and health impacts of industrial pollutants, with a focus on environmental justice. Air quality pollutants, including PM2.5, PM10, O3, NO2, CO, and SO2, were monitored for 75 days during the Summer, using the breezoMeter app. Python, Mapize, and QGIS software technologies were utilized for data analysis and visualization. Findings indicate a reduction in NO2 and CO levels, compared to existing literature. However, the persistent challenge of particulate matter suggests areas for further environmental management efforts. Additionally, the research suggests a significant disparity in air pollution exposure, probably affecting marginalized communities. Although the nature of the study might not fully capture annual pollution trends, the findings highlight the urgent need for the chemical industry to adopt efficient production methods and for policymakers to enhance air quality standards and enforcement, particularly in pollution-sensitive areas. The disproportionate impact of air pollution on vulnerable communities calls for a more inclusive approach to environmental justice, ensuring equitable distribution of clean air benefits and community involvement in pollution management decisions.

关键词： Air Quality Monitoring Chemical Industry Pollution Environmental Justice Health Implications Particulate Matter Case Study

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Overall Survival with Adjuvant Pembrolizumab in Renal-Cell Carcinoma

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四川生理科学杂志 2024年第4期46卷 872-872页

作者： Toni k Choueiri From Dana–Farber Cancer Institute and Harvard Medical School (T.k.C.) and beth Israel Deaconess Medical Center (D.F.M.) — all in boston Poznan University of Medical Sciences Poznan (P.T.) and Provincial Hospital in Torun Torun (P.S.) — both in Poland Samsung Medical Center Sungkyunkwan University School of Medicine (S.H.P.) and Asan Medical Center University of Ulsan College of Medicine (J.-L.L.) — both in Seoul South Korea beatson West of Scotland Cancer Centre and the University of Glasgow Glasgow (B.V.) Edinburgh Cancer Centre and the University of Edinburgh Edinburgh (S.N.S.) and Imperial College Healthcare NHS Trust (N.S.) Barts Health NHS Trust and the Royal Free NHS Foundation Trust Barts Cancer Institute (T.P.) and Queen Mary University of London (T.P.) London — all in the United Kingdom Fiona Stanley Hospital Perth WA (T.F.) and Maquarie University Sydney (H.G.) — both in Australia Fakultní Nemocnice Ostrava Ostrava (J.H.) and Palacký University and University Hospital Olomouc Olomouc (B.M.) — all in the Czech Republic Taipei Veterans General Hospital Taipei Taiwan (Y.-H.C.) Abramson Cancer Center Penn Medicine Philadelphia (N.B.H.) Fundación Arturo López Pérez Santiago Chile (M.M.) University Hospital bordeaux–Hôpital Saint-André Bordeaux (M.G.-G.) Hôpital Européen Georges Pompidou Université Paris Cité Paris (S.O.) and Centre Hospitalier Universitaire de Montpellier Montpellier (D.T.) — all in France the University of Texas Southwestern Medical Center Dallas (T.Z. H.H.) and Texas Oncology–Houston Houston (G.D.) Rocky Mountain Cancer Centers Aurora CO (J.M.B.) Omsk Clinical Oncology Dispensary Omsk Russia (E.K.) the University of Michigan Ann Arbor (A.A.) the University of Toyama Toyama Japan (H.K.) Instituto de Cancer e Transplante de Curitiba Curitiba Brazil (A.S.) the London Regional Cancer Program London Health Sciences Centre Western University London ON Canada (E.W.) and Merck Rahway NJ (J.C. A.E. J.E.B. R.F.P.).

background:Adjuvant pembrolizumab therapy after surgery for renal-cell carcinoma was approved on the basis of a significant improvement in disease-free survival in the kEYNOTE-564 *** the results regarding overall survival from the third prespecified interim analysis of the trial would also favor pembrolizumab was ***:In this phase 3,double-blind,placebo-controlled trial,we randomly assigned(in a 1:1 ratio)participants with clear-cell renal-cell carcinoma who had an increased risk of recurrence after surgery to receive pembrolizumab(at a dose of 200 mg)or placebo every 3 weeks for up to 17 cycles(approximately 1 year)or until recurrence,the occurrence of unacceptable toxic effects,or withdrawal of consent.A significant improvement in disease-free survival according to investigator assessment(the primary end point)was shown *** survival was the key secondary end *** was a secondary end point.

关键词： Carcinoma Survival specified

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Comparison of Spatial Interpolation Methods of Precipitation Data in Central Macedonia, Greece

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Computational Water, Energy, and Environmental Engineering 2024年第1期13卷 13-37页

作者： Athanasios k. Margaritidis Faculty of Agriculture Forestry and Natural Environment School of Agriculture Department of Hydraulics Soil Science & Agriculture Engineering Thessaloniki Greece

The purpose of this paper is to investigate the spatial interpolation of rainfall variability with deterministic and geostatic inspections in the Prefecture of kilkis (Greece). The precipitation data where recorded from 12 meteorological stations in the Prefecture of kilkis for 36 hydrological years (1973-2008). The cumulative monthly values of rainfall were studied on an annual and seasonal basis as well as during the arid-dry season. In the deterministic tests, the I.D.W. and R.b.F. checks were inspected, while in the geostatic tests, Ordinary kriging and Universal kriging respectively. The selection of the optimum method was made based on the least Root Mean Square Error (R.M.S.E.), as well as on the Mean Error (M.E.), as assessed by the cross validation analysis. The geostatical kriging also considered the impact of isotropy and anisotropy across all time periods of data collection. Moreover, for Universal kriging, the study explored spherical, exponential and Gaussian models in various combinations. Geostatistical techniques consistently demonstrated greater reliability than deterministic techniques across all time periods of data collection. Specifically, during the annual period, anisotropy was the prevailing characteristic in geostatistical techniques. Moreover, the results for the irrigation and seasonal periods were generally comparable, with few exceptions where isotropic methods yielded lower (R.M.S.E.) in some seasonal observations.

关键词： Interpolation kriging I.D.W. Precipitation Greece

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Ground-based and additional science support for SMILE

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Earth and Planetary Physics 2024年第1期8卷 275-298页

作者： J.A.Carter M.Dunlop C.Forsyth k.Oksavik E.Donovon A.kavanagh S.E.Milan T.Sergienko R.C.Fear D.G.Sibeck M.Connors T.Yeoman X.Tan M.G.G.T.Taylor k.McWilliams J.Gjerloev R.barnes D.D.billet G.Chisham A.Dimmock M.P.Freeman D.-S.Han M.D.Hartinger S.-Y.W.Hsieh Z.-J.Hu M.k.James L.Juusola k.kauristie E.A.kronberg M.Lester J.Manuel J.Matzka I.McCrea Y.Miyoshi J.Rae L.Ren F.Sigernes E.Spanswick k.Sterne A.Steuwer T.Sun M.-T.Walach b.Walsh C.Wang J.Weygand J.Wild J.Yan J.Zhang Q.-H.Zhang Planetary Sciences Group School of Physics and AstronomyUniversity of LeicesterUniversity RoadLeicesterLE17RHUK Rutherford Appleton Laboratory Space Science Technology Facilities CouncilOxfordshireUK School of Space and Environment Beihang UniversityBeijing 100191China key Laboratory of Space Environment Monitoring and Information Processing Ministry of Industry and Information TechnologyBeijing 100017China Department of Space and Climate Physics UCLMullard Space Science LaboratoryHolmbury St.MaryDorkingSurreyRH56NTUK birkeland Centre for Space Science Department of Physics and Technology.University of BergenBergenNorway Department of Physics and Astronomy University of Calgary2500 University DriveCalgaryAlbertaCanada T2N 1N4 british Antarctic Survey CambridgeUK Swedish Institute of Space Physics KirunaSweden West Highfield Campus University of SouthamptonUniversity RoadSO171BJUK Goddard Space Flight Center NASAGreenbeltMarylandUSA Athabasca University AthabascaCanada ESTEC European Space AgencyNetherlands University of Saskatchewan SaskatoonCanada The Johns Hopkins University Applied Physics Laboratory LaurelMarylandUSA Swedish Institude of Space Physics UppsalaSE 75121Sweden Tongji University Shanghai 200092China Center for Space Plasma Physics Space Science Institute4765 Walnut Street Suite BBoulderColorado80301USA Polar Research Institute of China Shanghai 200136China Finnish Meteorological Institute(FMI) Finland Department of Earth and Environmental Sciences(Geophysics) Ludwig Maximilian University of Munich(LMU)MunichTheresienstr.41MunichD-80333Germany Canadian Space Agency MontrealCanada GFZ German Research Centre for Geosciences PotsdamGermany Nagoya University Institute for Space Earth Environment ResearchCenter for Integrated Data ScienceNagoyaAichiJP 464-8601 Northumbria University Newcastle upon TyneTyne and WearUK NE18ST National Space Science Center Chinese Academy SciencesBeijing 100190China Arctic Geophysics University Centre in Svalbard

The joint European Space Agency and Chinese Academy of Sciences Solar wind Magnetosphere Ionosphere Link Explorer(SMILE)mission will explore global dynamics of the magnetosphere under varying solar wind and interplanetary magnetic field conditions,and simultaneously monitor the auroral response of the Northern Hemisphere *** these large-scale responses with medium and fine-scale measurements at a variety of cadences by additional ground-based and space-based instruments will enable a much greater scientific impact beyond the original goals of the SMILE ***,we describe current community efforts to prepare for SMILE,and the benefits and context various experiments that have explicitly expressed support for SMILE can offer.A dedicated group of international scientists representing many different experiment types and geographical locations,the Ground-based and Additional Science Working Group,is facilitating these *** include constructing an online SMILE Data Fusion Facility,the discussion of particular or special modes for experiments such as coherent and incoherent scatter radar,and the consideration of particular observing strategies and spacecraft *** anticipate growing interest and community engagement with the SMILE mission,and we welcome novel ideas and insights from the solar-terrestrial community.

关键词： magnetosphere ionosphere magnetosphere-ionosphere coupling ground-based experimentation SMILE conjunctions missions

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SARS-CoV-2 variants are associated with different clinical courses in children with MIS-C

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World Journal of Pediatrics 2024年第2期20卷 143-152页

作者： Andres F.Moreno Rojas Emelia bainto Helen Harvey Adriana H.Tremoulet Jane C.burns kirsten b.Dummer Department of Pediatrics Division of Pediatric CardiologyUniversity of California San Diegoand Rady Children’s Hospital3020 Children’s Way MC 5004San DiegoCA 92123USA kawasaki Disease Research Center La JollaCAUSA Department of Pediatrics Division of Pediatric Critical CareUniversity of California San Diegoand Rady Children’s HospitalSan DiegoCAUSA Department of Pediatrics University of California San Diegoand Rady Children’s HospitalSan DiegoCAUSA

background Recent infection with SARS‑CoV-2 in children has been associated with multisystem inflammatory syndrome in children(MIS-C).SARS‑CoV-2 has undergone different *** publications exist about specific variants and their correlation with the severity of *** This was a single-center,retrospective study including all patients admitted with MIS-C at Rady Children’s Hospital-San Diego between May 2020 and March *** epidemiologic data,including viral genomic information,were obtained from public ***,clinical presentation,laboratory values,and outcomes were obtained from electronic medical *** The analysis included 104 pediatric *** MIS-C waves were *** variants in San Diego during the first wave included clades 20A to *** the second wave,there were variants from clades 20A to C,20G,21C(Epsilon),20I(Alpha),and 20J(Gamma).The third wave had Delta strains(clades 21A,21I,and 21J),and the fourth had Omicron variants(clades 21k,21L,and 22C).MIS-C presented with similar symptoms and laboratory findings across all *** patients were admitted to the pediatric intensive care unit(PICU)(74%)and required inotropic support(63%)during the second *** of the patients required mechanical circulatory support,and only two required invasive ventilatory *** was no *** The various strains of SARS-CoV-2 triggered MIS-C with differing severities,with the second wave having a more severe clinical *** the differences in disease severity across variants were due to changes in the virus or other factors remains unknown.

关键词： Complications COVID-19 MIS-C SARS-CoV-2 variants

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Hole-Selective Contact with Molecularly Tailorable Reactivity for Passivating High-Performing Inverted Perovskite Solar Cells

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CCS Chemistry 2024年第7期6卷 1654-1661页

作者： Wenlin Jiang Yingie Hu Fengzhu Li Francis R.Lin Alex k-Y.Jen Department of Materials Science and Engineering City University of Hong KongKowloonHong Kong China 999077 Department of Chemistry City University of Hong KongKowloonHong Kong China 999077 Hong kong Institute for Clean Energy City University of Hong KongKowloonHong Kong China 999077 State key Laboratory of Marine Pollution City University of Hong KongKowloonHong Kong China 999077

The precisely customizable attributes of self-assembled monolayers(SAMs)molecules at the atomic level hold the potential to facilitate efficient hole selection and interface passivation ***,the correlation between the exposure of passivating groups on the surface and device performance remains ***,we introduce two newly designed SAM molecules,Cbz2S and Cbz2SMe,incorporating cyclic disulfide or two flanking thiomethyls by modifying the 4,5-position of carbazole to adjust the Lewis basicity of the SAM-modified *** possessing suitable energetic alignment,Cbz2S with more-exposed sulfur atoms exhibited inferior device performance due to excessive reactivity,leading to an overpopulation of PbI2 crystallites at the buried perovskite *** contrast,the screening effect from the methyl groups of Cbz2SMe optimized SAM reactivity,exquisitely integrating buried interface passivation and hole selection ***,the champion inverted perovskite solar cell(PSC)employing Cbz2SMe achieved an impressive power conversion efficiency of 24.42%,accompanied by prolonged *** work demonstrates the feasibility of incorporating Lewis-basic passivation groups into SAM molecules and elucidates the relationship between the reactivity of SAM passivation groups and device *** findings provide valuable insights for the design of novel multifunctional SAM molecules,further advancing the performance of PSCs.

关键词： self-assembled monolayer perovskite solar cell hole-selective layer carbazole derivatives defect passivation

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