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Multiphysics processes in the interfacial transition zone of fiber-reinforced cementitious composites under induced curing pressure and implications for mine backfill materials: A critical review

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International Journal of Minerals,Metallurgy and Materials 2023年第8期30卷 1474-1489页

作者： brett Holmberg Liang Cui Department of Civil Engineering Lakehead UniversityThunder BayON P7B 5E1Canada

The mesoscale fiber-matrix interfacial transition zone(FM-ITZ) under induced curing pressure plays a key role in the effectiveness of fiber reinforcement and the engineering application of fiber-reinforced cementitious composites(FRCCs). This critical review establishes the link among induced curing pressure(i.e., external loading condition), multiphysics processes(i.e., internal governing mechanism), and interface behavior(i.e., material behavior) for FRCC materials through analysis of the state-of-the-art research findings on the FM-ITZ of FRCC materials. The following results are obtained. For the mechanical process, the induced curing pressure changes the stress state and enhances multicracking behavior, which can strengthen the FM-ITZ. For the hydraulic process, the strengthened seepage of the FM-ITZ under induced curing pressure weakens the effective stress and exaggerates the deficiency in water retention capacity between the bulk matrix and the FMITZ. For the thermal process, the induced curing pressure causes a steep temperature gradient in the FM-ITZ and thus influences the temperature evolution and thermally-induced microcracks in the FM-ITZ. For the chemical process, the induced curing pressure enhances hydration kinetics and results in the formation of additional hydration products in the FM-ITZ. Moreover, recommendations are proposed on the basis of findings from this review to facilitate the implementation of fiber reinforcement in cemented paste backfill technology.

关键词： cemented paste backfill cementitious composites interfacial transition zone fiber reinforcement multiphysics induced curing pressure

Epidemiology of ovarian cancer:a review

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Cancer biology & Medicine 2017年第1期14卷 9-32页

作者： brett M.Reid Jennifer b.Permuth Thomas A.Sellers Department of Cancer Epidemiology Division of Population SciencesMoffitt Cancer CenterTampa 33612FLUSA

Ovarian cancer(OC) is the seventh most commonly diagnosed cancer among women in the world and the tenth most common in China. Epithelial OC is the most predominant pathologic subtype, with five major histotypes that differ in origination,pathogenesis, molecular alterations, risk factors, and prognosis. Genetic susceptibility is manifested by rare inherited mutations with high to moderate penetrance. Genome-wide association studies have additionally identified 29 common susceptibility alleles for OC, including 14 subtype-specific alleles. Several reproductive and hormonal factors may lower risk, including parity, oral contraceptive use, and lactation, while others such as older age at menopause and hormone replacement therapy confer increased risks. These associations differ by histotype, especially for mucinous OC, likely reflecting differences in etiology. Endometrioid and clear cell OC share a similar, unique pattern of associations with increased risks among women with endometriosis and decreased risks associated with tubal ligation. OC risks associated with other gynecological conditions and procedures, such as hysterectomy,pelvic inflammatory disease, and polycystic ovarian syndrome, are less clear. Other possible risk factors include environmental and lifestyle factors such as asbestos and talc powder exposures, and cigarette smoking. The epidemiology provides clues on etiology,primary prevention, early detection, and possibly even therapeutic strategies.

关键词： Ovarian cancer epidemiology risk factors histology reproductive history

Prevalence of diverticulosis in recurrent Clostridium difficile infection

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World Journal of Gastroenterology 2010年第3期16卷 345-347页

作者： Michael J Lipp Odelya E Pagovich David Rabin Albert D Min brett b bernstein Division of Digestive Diseases Beth Israel Medical Center Division of Medicine Beth Israel Medical Center

AIM:To re-evaluate the theory that colonic diverticulosis is associated with relapse of Clostridium difficile associated disease (CDAD) in light of data suggesting increasing rates of CDAD infection and ***: Charts were reviewed for patients with recurrent CDAD who had also had a prior colonoscopy or flexible sigmoidoscopy. An age and gender matched control group was used to compare the prevalence of ***: Twenty-two patients met the study criteria, and the prevalence of diverticulosis in patients with CDAD relapse was 23% compared to 32% in age and sex matched controls (P=0.44). A significant proportion of patients with CDAD relapse had comorbidities associated with immune ***: Diverticulosis does not appear to be associated with CDAD relapse.

关键词： Clostridium diff icile Diverticulosis Relapse Immune suppression Clostridium difficile associated disease

Assessment and Assimilation of FY-3 Humidity Sounders and Imager in the UK Met Office Global Model

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Advances in Atmospheric Sciences 2018年第8期35卷 46-58页

作者： Fabien CARMINATI brett CANDY William bELL Nigel ATKINSON UK Met Office Exeter EX1 3PBUK ECMWF ReadingUK

China＇s FengYnn 3 （FY-3） polar orbiting satellites axe set to become an important sonrce of observational data for nu- merical weather prediction （NWP）, atmospheric reanalyses, and climate monitoring studies over the next two decades. As part of the Climate Science for Service Partnership China （CSSP China） prograln, FY-3b Microwave Humidity Sounder 1 （MWHS-1） and FY-3C MWHS-2 observations have been thoroughly assessed and prepared for operational assimilation. This represents the first time observations from China＇s polar orbiting satellites have been used in the UK＇s global NWP model. Since 2016, continuous data quality monitoring has shown occasional bias changes found to be correlated to changes in the energy supply scheme regulating the platform heating system and other transient anomalies. Nonetheless, MWHS-1 and MWHS-2 significantly contribute to the 24-h forecast error reduction by 0.3% and 0.6%, respectively, and the combination of both instruments is shown to improve the fit to the model background of independent sounders by up to 1%. The observations from the Microwave Radiation Imager （MWRI） also are a potentially significant source of benefits for NWP models, but a solar-dependent bias observed in the instrument half-orbits has prevented their assimilation. This paper presents the bases of a correction scheme developed at the Met Office for the purpose of a future assimilation of MWRI data.

关键词： Microwave Humidity Sounder Microwave Radiation Imager numerical weather prediction

cffdrs: an R package for the Canadian Forest Fire Danger Rating System

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Ecological Processes 2017年第1期6卷 30-40页

作者： Xianli Wang b.Mike Wotton Alan S.Cantin Marc-AndréParisien Kerry Anderson brett Moore Mike D.Flannigan Great Lakes Forestry Centre Canadian Forest ServiceNatural Resources Canada1219 Queen Street EastSault Ste.MarieON P6A 2E5Canada Department of Renewable Resources University of Alberta751 General Service BuildingEdmontonAB T6G 2H1Canada Faculty of Forestry University of Toronto33 Willcocks St.TorontoON M5S 3B3Canada Northern Forestry Centre Canadian Forest ServiceNatural Resources Canada5320-122nd StreetEdmontonAB T6H 3S5Canada

Introduction:The Canadian Forest Fire Danger Rating System(CFFDRS)is a globally known wildland fire risk assessment system,and two major components,the fire weather index system and the fire behavior prediction system,have been extensively used both nationally and internationally to aid operational wildland fire decision ***:In this paper,we present an overview of an R package cffdrs,which is developed to calculate components of the CFFDRS,and highlight some of its *** particular,we demonstrate how these functions could be used for large data *** and Discussion:With this cffdrs package,we provide a portal for not only a collection of R functions dealing with all available components in CFFDRS but also a platform for various additional developments that are useful for the understanding of fire occurrence and *** is the first time that all relevant CFFDRS methods are incorporated into the same platform,which can be accessed by both the management and research communities.

关键词： Fire behavior prediction system Fire weather index system Forest fire Forest fire risk Fuel moisture Landscape ecology

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开发细菌小分子

生物技术世界 2011年第2期8卷 36-41页

作者： L.Caetano M.Antunes Julian E.Davies b.brett Finlay 刘磊

各种制药企业花费大量的人力物力找遍地球每一个角落来寻找意外的收获。但我们仅仅需要重新审视我们的肠道，其中上万种细菌持续地产生着大量的生物活性小分子物质。

关键词：小分子物质细菌开发制药企业生物活性

Single nucleotide polymorphisms linked to quantitative trait loci for grain quality traits in wheat

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The Crop Journal 2016年第1期4卷 1-11页

作者： Chunlian Li Guihua bai Shiaoman Chao brett Carver Zhonghua Wang College of Agronomy Northwest A&F University State Key Laboratory of Crop Stress biology for Arid Areas Northwest A&F University Agronomy Department Kansas State University Hard Winter Wheat Genetics Research Unit USDA-ARS Cereal Crops Research Unit USDA-ARS Department of Plant and Soil Science Oklahoma State University

Wheat(Triticum aestivum L.) grain quality traits that are controlled by quantitative traits loci(QTL) define suitable growing areas and potential end-use products of a wheat cultivar. To dissect QTL for these traits including protein content(GPC); test weight(TW); single kernel characterization system(SKCS)-estimated kernel weight(SKW); kernel diameter(KD);kernel hardness measured by near-infrared reflectance spectroscopy(NIRS) hardness index(NHI); and SKCS-hardness index(SHI), a high-density genetic map with single nucleotide polymorphism(SNP) and simple sequence repeat(SSR) markers was developed using recombinant inbred lines(RILs) derived from Ning7840 × Clark. The RILs were evaluated for these quality traits in seven Oklahoma environments from 2001 to 2003. A total of 41 QTL with additive effects on different traits were mapped on most wheat chromosomes,excluding 1A, 2A, 3D, 4D, 6D, and 7b. Seven chromosome regions showed either tightly linked QTL or QTL with pleiotropic effects on two to four traits. Ten pairs of QTL showed additive × additive effects(AA), four QTL were involved in additive × environment(AE)effects, and one was involved in AAE effects. Two to eleven QTL for each of the six traits and139 tightly linked markers to these QTL were identified. The findings shed light on the inheritance of wheat grain quality traits and provide DNA markers for manipulating these important traits to improve quality of new wheat cultivars.

关键词： Triticum aestivum Epistasis Grain quality traits QTL×environments interaction SNP

An adaptive fuel cell hybrid vehicle propulsion sizing model

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iEnergy

iEnergy 2024年第1期3卷 59-72页

作者： Jia Di Yang Paul R.Shearing Jason Millichamp Theo Suter Dan J.L.brett James b.Robinson Electrochemical Innovation Lab Department of Chemical EngineeringUniversity College LondonLondon WC1E 7JEUK Advanced Propulsion Lab MarshgateUniversity College LondonLondon E202AEUK ZERO Institute Holywell HouseOsney MeadUniversity of OxfordOxfordOX20ES The Faraday Institution Quad OneBecquerel AvenueHarwell Science and Innovation CampusDidcot OX110RAUK

As we enter the age of electrochemical propulsion,there is an increasing tendency to discuss the viability or otherwise of different electrochemical propulsion systems in zero-sum *** discussions are often grounded in a specific use case;however,given the need to electrify the wider transport sector it is evident that we must consider systems in a holistic *** designed adequately,the hybridisation of power sources within automotive applications has been demonstrated to positively impact fuel cell efficiency,durability,and cost,while having potential benefits for the safety of *** this paper,the impact of the fuel cell to battery hybridisation degree is explored through the key design parameter of system *** fuel cell electric hybrid vehicle(FCHEV)scenarios of various hydridisation degrees,including light-duty vehicles(LDVs),Class 8 heavy goods vehicles(HGVs),and buses are modelled to enable the appropriate sizing of the proton exchange membrane(PEMFC)stack and lithium-ion battery(Lib)pack and additional balance of *** operating conditions of the modelled PEMFC stack and battery pack are then varied under a range of relevant drive cycles to identify the relative performance of the *** extending the model further and incorporating a feedback loop,we are able to remove the need to include estimated vehicle masses a priori enabling improving the speed and accuracy of the model as an analysis tool for vehicle mass and performance estimation.

关键词： Proton exchange membrane(PEMFC) lithium-ion batteries fuel cell electric hybrid vehicle(FCHEV) electric propulsion powertrain modelling

A transgenic pig model expressing a CMV-ZsGreen1 reporter across an extensive array of tissues

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The Journal of biomedical Research 2021年第2期35卷 163-173页

作者： Amy T.Desaulniers Rebecca A.Cederberg Elizabeth P.Carreiro Channabasavaiah b.Gurumurthy brett R.White Department of Animal Science University of Nebraska-LincolnLincolnNE 68583-0908USA Department of Pharmacology and Experimental Neuroscience University of Nebraska Medical CenterOmahaNE 68198-5930USA

Since genetic engineering of pigs can benefit both biomedicine and agriculture,selecting a suitable gene promoter is critically *** cytomegalovirus(CMV)promoter,which can robustly drive ubiquitous transgene expression,is commonly used at present,yet recent reports suggest tissue-specific activity in the *** objective of this study was to quantify ZsGreen1 protein(in lieu of CMV promoter activity)in tissues from pigs harboring a CMV-ZsGreen1 transgene with a single integration *** samples(n=35)were collected from neonatal hemizygous(n=3)and homozygous(n=3)piglets and ZsGreen1 abundance was determined via ***1 was detected in all tissues,except hypothalamus,kidney cortex and *** expression patterns of homozygous and hemizygous piglets were similar(P>0.05).However,quantification revealed that ZsGreen1 protein levels were *** neural/endocrine tissues,ZsGreen1 abundance was highest in the anterior pituitary gland,intermediate in the cerebellum and lowest in the cerebrum,spinal cord and posterior pituitary(Pbundant in the salivary gland than esophagus,stomach,pancreas,duodenum,jejunum,ileum,spleen,colon,gallbladder and liver(Pbers;Pbeled organs and a valuable tool to advance genome editing research.

关键词： gene expression profiling CMV promoter ZsGreen1 biomedical model genome editing