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Colony-stimulating factor 3 and its receptor promote leukocyte immunoglobulin-like receptor b2 expression and ligands in gastric

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World Journal of Gastrointestinal Oncology 2025年第2期17卷 198-210页

作者： Long Wang qi Wu Zong-Wen Zhang Hui Zhang Hui Jin Xin-Liang Zhou Jia-Yin Liu Dan Li Yan Liu Zhi-Song Fan Department of Oncology The Fourth Hospital of Hebei Medical UniversityShijiazhuang 050011Hebei ProvinceChina

bACKGROUND Colony-stimulating factor 3(CSF3)and its receptor(CSF3R)are known to promote gastric cancer(GC)growth and ***,their effects on the immune microenvironment remain *** analysis indicated a potential link between CSF3R expression and the immunosuppressive receptor leukocyte immunoglobulin-like receptor b2(LILRb2)in *** hypothesized that CSF3/CSF3R may regulate LILRb2 and its ligands,angiopoietin-like protein 2(ANGPTL2)and human leukocyte antigen-G(HLA-G),contributing to *** To investigate the relationship between CSF3/CSF3R and LILRb2,as well as its ligands ANGPTL2 and HLA-G,in *** Transcriptome sequencing data from The Cancer Genome Atlas were analyzed,stratifying patients by CSF3R *** expressed genes and immune checkpoints were ***(IHC)was performed on GC *** analyses of CSF3R,LILRb2,ANGPTL2,and HLA-G were conducted using The Cancer Genome Atlas data and IHC *** cells were treated with CSF3,and expression levels of LILRb2,ANGPTL2,and HLA-G were measured by quantitative reverse transcriptase-polymerase chain reaction and western *** Among 122 upregulated genes in high CSF3R expression groups,LILRb2 showed the most significant *** results indicated high expression of LILRb2(63.0%),ANGPTL2(56.5%),and HLA-G(73.9%)in GC *** positive correlations existed between CSF3R and LILRb2,ANGPTL2,and HLA-G mRNA levels(Pbetween CSF3R and LILRb2(Pbut not ANGPTL2(P>0.05).CSF3 increased LILRb2,ANGPTL2,and HLA-G expression in GC *** nuclear ribonucleoprotein H1 modulation significantly altered their expression,impacting CSF3’s regulatory *** The CSF3/CSF3R pathway may contribute to immunosuppression in GC by upregulating LILRb2 and its ligands,with heterogeneous nuclear ribonucleoprotein H1 playing a regulatory role.

关键词： Gastric cancer Immunosuppressive receptor Colony-stimulating factor 3 Colony-stimulating factor 3 receptor Leukocyte immunoglobulin-like receptor b2 Angiopoietin-like protein 2 Human leukocyte antigen-G Heterogeneous nuclear ribonucleoprotein H1

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中国古代小说美学的历史流变与时代特征

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学习与探索 2025年第2期 149-159页

作者：祁志祥海南师范大学人文社会科学高等研究院上海交通大学人文学院

中国古代小说美学星光熠熠,丰富多彩。本文基于对中国古代小说批评史若干个案的研究,以“美是有价值的乐感对象”为视角,聚焦价值与乐感,分析阐释中国古代小说批评呈现的美学思想及其历史坐标、前后关联与阶段特征,旨在为读者系统把握... 详细信息

中国古代小说美学星光熠熠,丰富多彩。本文基于对中国古代小说批评史若干个案的研究,以“美是有价值的乐感对象”为视角,聚焦价值与乐感,分析阐释中国古代小说批评呈现的美学思想及其历史坐标、前后关联与阶段特征,旨在为读者系统把握中国古代小说美学的思想精髓与演进脉络提供独特视角与方便门径。先秦至宋的小说评点处于起步阶段,人们认识到小说“小道可观”,以奇幻取胜。明代小说批评走向繁荣,讨论的美学问题集中在小说主题与教化大道的联系,虚构奇幻与真实情理的对立统一关系。清代小说批评在道德寄托、人物塑造、情节设计、审美效果等方面作出深入阐释,将中国古代小说美学推向辉煌的高峰。

关键词：中国古代小说批评美学思想历史演变时代特征

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Lamb wave TDTE super-resolution imaging assisted by deep learning

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Chinese Physics b 2025年第1期34卷 357-366页

作者： Liu-Jia Sun qing-bang Han and qi-Lin Jin College of Information Science and Engineering Hohai UniversityChangzhou 213200China

Ultrasonic Lamb waves undergo complex mode conversion and diffraction at non-penetrating defects, such as plate corrosion and cracks. Lamb wave imaging has a resolution limit due to the guided wave dispersion characteristics and Rayleigh criterion limitations. In this paper, a full convolutional network is designed to segment and reconstruct the received signals, enabling the automatic identification of target modalities. This approach eliminates clutter and mode conversion interference when calculating direct and accompanying acoustic fields in time-domain topological energy(TDTE) ***, the measured accompanying acoustic field is reversed for adaptive focusing on defects and enhance the imaging quality. To circumvent the limitations of the Rayleigh criterion, the direct acoustic field and the accompanying acoustic field were fused to characterize the pixel distribution in the imaging region, achieving Lamb wave super-resolution imaging. Experimental results indicate that compared to the sign coherence factor-total focusing method(SCF-TFM),the proposed method achieves a 31.41% improvement in lateral resolution and a 29.53% increase in signal-to-noise ratio for single-blind-hole defects. In the case of multiple-blind-hole defects with spacings greater than the Rayleigh criterion resolution limit, it exhibits a 27.23% enhancement in signal-to-noise ratio. On the contrary, when the defect spacings are relatively smaller than the limit, this method has a higher resolution limit than SCF-TFM in super-resolution imaging.

关键词： Lamb waves asymmetric defects fully convolutional network time-domain topological energy imaging super-resolution

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Ab initio calculation of the ground and first excited states of the lithium dimer

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Communications in Theoretical Physics 2021年第12期73卷 129-136页

作者： JianJun qi YuYao bai qianqian Guo Yong-Chang Han Maksim b Shundalau Department of Physics Dalian University of TechnologyDalian 116024China DUT-bSU Joint Institute Dalian University of TechnologyDalian 116024China Physics Department Belarusian State UniversityMinskBelarus

based on a high level ab initio calculation which is earned out with the multireference configuration interaction method under the aug-cc-pVXZ(AVXZ)basis sets,X=T,Q,5,the accurate potential energy curves(PECs)of the ground state X^(1)Σ_(g)^(+)and the first excited state A^(1)Σ_(u)^(+)of Li_(2)are *** fitting the ab initio potential energy points with the MurrellSorbie potential function,the analytic potential energy functions(APEFs)are *** molecular bond length at the equilibnum(R_(e)),the potential well depth(D_(e)),and the spectroscopic constants(b_(e),ω_(e),α_(e),andω_(e)χ_(e))for the X^(1)Σ_(g)^(+)state and the A^(1)Σ_(u)^(+)state are deduced from the *** vibrational energy levels of the two electronic states are obtained by solving the time-independent Schrodmger equation with the Founer gnd Hamiltonian *** the spectroscopic constants and the vibrational levels agree well with the experimental *** Franck-Condon factors(FCFs)corresponding to the transitions from the vibrational level(v’=0)of the ground state to the vibrational levels(v"=0-74)of the first excited state have been *** FCF for the vibronic transition of A^(1)Σ_(u)^(+)(v"=0)←X^(1)Σ_(g)^(+)(v’=0)is the *** PECs and corresponding spectroscopic constants provide reliable theoretical references to both the spectroscopic and the molecular dynamic studies of the Li_(2)dimer.

关键词： potential energy curve spectroscopic constants vibrational levels

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Recent strategies to improve moisture stability in metal halide perovskites materials and devices

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Journal of Energy Chemistry 2022年第2期31卷 219-235页

作者： Chenxiao Zhou Alexey b.Tarasov Eugene A.Goodilin Pengwan Chen Hao Wang qi Chen School of Materials Science and Engineering Beijing Institute of TechnologyBeijing 100081China Faculty of Materials Science Lomonosov Moscow State UniversityLenin Hills119991 MoscowRussia Department of Chemistry Lomonosov Moscow State UniversityLenin Hills119991 MoscowRussia State Key Laboratory of Explosion Science and Technology Beijing Institute of TechnologyBeijing 100081China beijing Institute of Technology Chongqing Innovation Center Chongqing 401120China

At present,the stability of the new generation of solar cells based on hybrid perovskites is the bottleneck for their practical *** effects,high temperature,ultraviolet light,humidity and other known or still unknown factors might cause reduction of effectiveness or even irreversible loss of materials properties due to decomposition of functional layers within perovskite solar cells(PSCs).These factors alone have a serious impact on each component of the device,while their combinations lead to much more complicated effects and *** review focuses on the stability of PSCs and the degradation of the device in a humid *** assess the instability factors and deep-seated principles of evolution of the device structure in a humidity environment with the emphasis on the influence on their *** related solutions are reviewed from the perspective of the encapsulation,perovskite active layer,carrier transport layer and *** with the latest research,we believe that the waterproof strategy of PSCs requires either tight encapsulation or thorough modifications in the device ***,it is important to develop feasible strategies to improve the overall device stability over humid according to the target characteristics of various devices.

关键词： Perovskite solar cells Water Stability Composition Encapsulation

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Magnetic properties of Fe_(3(1-x))Cr_(3x)C alloys

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International Journal of Minerals,Metallurgy and Materials 2009年第3期16卷 314-316页

作者： Feng-qi Zhao O. Tegus b. Fuquan E. brück Inner Mongolia Key Laboratory for Physics and Chemistry of Functional Materials College of Physics and Electron Information Inner Mongolia Normal University Hohhot 010022 China Van der Waals-Zeeman Instituut Universiteit van Amsterdam Valckenierstraat 65 1018XE Amsterdam Netherlands

The magnetic properties of Fe3（1-x）Cr3xC alloys with x=0.05, 0.1, 0.15, and 0.2, which crystallize in the cementite Fe3C-type structure with space group Pnma, were investigated by means of magnetization measurements. These alloys show temperature-induced second-order magnetic phase transitions. The Curie temperature （Tc） of these alloys decreases with increasing x. The isothermal magnetic-entropy changes of these alloys were derived from the magnetic isotherms measured with increasing temperature and increasing field. The maximum values of the magnetic-entropy change are about 0.9 and 3.6 J·kg^-1·K^-1 at Tc =360 K for x = 0.05 in a magnetic field change from 0 to 1 T and 0 to 5 T, respectively.

关键词： magnetic properties magnetocaloric effect magnetic-entropy change magnetic refrigeration

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Improved reference-frame-independent quantum key distribution with intensity fluctuations

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Chinese Physics b 2025年第2期34卷 48-52页

作者： Zi-qi Chen Hao-bing Sun Ming-Shuo Sun qin Wang Institute of Quantum Information and Technology Nanjing University of Posts and TelecommunicationsNanjing 210003China broadband Wireless Communication and Sensor Network Technology Key Laboratory of Ministry of EducationNanjing University of Posts and TelecommunicationsNanjing 210003China

Reference-frame-independent quantum key distribution(RFI-QKD) can avoid real-time calibration operation of reference frames and improve the efficiency of the communication process. However, due to imperfections of optical devices,there will inevitably exist intensity fluctuations in the source side of the QKD system, which will affect the final secure key rate. To reduce the influence of intensity fluctuations, an improved 3-intensity RFI-QKD scheme is proposed in this *** considering statistical fluctuations and implementing global parameter optimization, we conduct corresponding simulation analysis. The results show that our present work can present both higher key rate and a farther transmission distance than the standard method.

关键词： quantum key distribution intensity fluctuations decoy-state method

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First discovery of coesite in eclogite from East Kunlun, northwest China

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Science bulletin 2018年第23期63卷 1536-1538页

作者： Hengzhe bi Shuguang Song Jinlong Dong Liming Yang Shengsheng qi Mark b.Allen MOE Key Laboratory of Orogenic belt and Crustal Evolution School of Earth and Space SciencesPeking UniversityBeijing 100871China qinghai bureau of Geological Survey Xining 810012China Department of Earth Sciences Durham UniversityDurham DH13LEUK

Ultrahigh-pressure (UHP)metamorphism plays important roles in continental *** of this process has been enhanced by the discovery of coesite and micro-diamond from supracrustal rocks [1].Such UHP mineral inclusions provide unequivocal evidence that the least dense part of the lithosphere can be buried to 100-150km or more,and then returned to the ***,an ultrahigh-pressure polymorph of SiO2stable above 2.7GPa at metamorphic temperatures,is one of the most important index minerals for UHP metamomhism [1,2].

关键词： Cobalt feldspar East Kunlun eclogite

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Development and characterization of bacterial wilt-resistant synthetic polyploid peanuts

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The Crop Journal 2025年第1期13卷 125-134页

作者： Pei Du Fanpei Zeng qian Wang Lijuan Miao Feiyan qi Meili Yang Xiao Wang Hua Liu Guoquan Chen Liuyang Fu Suoyi Han Ziqi Sun Li qin Wenzhao Dong Xinyou Zhang The Shennong Laboratory/Nation Industrial Innovation Centre for bio-breeding/Key Laboratory of Oil Crops in Huang-Huai-Hai Plains Ministry of Agriculture/Henan Provincial Key Laboratory for Oil Crops Improvement/Institute of Crop Molecular BreedingHenan Academy of Agricultural SciencesPostgraduate T&R Base of Zhengzhou UniversityZhengzhou 450002HenanChina School of Agricultural Sciences Zhengzhou UniversityZhengzhou 450001HenanChina School of Life Science Zhengzhou UniversityZhengzhou 450001HenanChina Hebi Academy of Agricultural Sciences Hebei 458031HenanChina

Wild peanut(Arachis)species are promising sources of disease resistance for improving peanut *** objective of this study was to assess cross-compatibility among cultivated and wild peanuts in crosses between eight peanut cultivars and 27 wild species carrying the A,b,E,Ex,F,K,P,and H *** culture and chromosome doubling led to polyploids representing hybrids between cultivated peanut and ***,***,***,***,and *** first two showed greater resistance to bacterial wilt than their cultivated *** markers were developed for verifying the hybrids and for identifying translocation or introgression lines with alien chromosome fragments.

关键词： Peanut Wild species Cross compatibility Polyploids bacterial wilt

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低蛋白质饲粮中添加发酵饲料对生长猪生长性能、血清指标和经济效益的影响

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动物营养学报 2025年第1期37卷 261-270页

作者：张俊峰冷来福齐仁立王敬邱小宇王琪重庆市畜牧科学院荣昌402460 生猪技术创新中心(重庆) 荣昌402460 西南大学动物科学技术学院北碚400715

本试验旨在研究低蛋白质饲粮中添加发酵饲料(发酵菜籽粕和发酵白酒糟)对生长猪生长性能、血清指标和经济效益的影响。选择72头健康、体重[(31.21±0.31)kg]相近的“长白×荣昌”生长猪,随机分为3组,每组6个重复,每个重复4头猪。对照组... 详细信息

本试验旨在研究低蛋白质饲粮中添加发酵饲料(发酵菜籽粕和发酵白酒糟)对生长猪生长性能、血清指标和经济效益的影响。选择72头健康、体重[(31.21±0.31)kg]相近的“长白×荣昌”生长猪,随机分为3组,每组6个重复,每个重复4头猪。对照组和低蛋白质组饲喂玉米-豆粕型饲粮,饲粮粗蛋白质水平分别为15.15%和13.66%;低蛋白质-发酵组以发酵菜籽粕和发酵白酒糟代替饲粮中的豆粕,其添加水平分别为10%和5%,饲粮粗蛋白质水平为13.72%。预试期3 d,正试期39 d。结果表明:1)各组之间生长性能无显著差异(P>0.05)。2)与对照组相比,低蛋白质组和低蛋白质-发酵组的血清尿素氮含量显著降低(P<0.05)。3)与对照组相比,低蛋白质组和低蛋白质-发酵组的血清免疫球蛋白A含量显著提高(P<0.05),血清白细胞介素-6含量显著降低(P<0.05);低蛋白质-发酵组的血清白细胞介素-10含量显著提高(P<0.05)。4)与对照组相比,低蛋白质组和低蛋白质-发酵组的血清超氧化物歧化酶活性显著提高(P<0.05);与对照组和低蛋白质组相比,低蛋白质-发酵组的血清还原型谷胱甘肽含量和总抗氧化能力显著提高(P<0.05)。5)与对照组相比,低蛋白质组和低蛋白质-发酵组的饲料成本分别降低了0.04、0.30元/kg,毛利润分别增加了5.58、11.43元/头。由此可见,在低蛋白质饲粮中添加发酵菜籽粕和发酵白酒糟对生长猪生长性能无影响,能提高免疫功能和抗氧化能力,降低血清尿素氮含量,改善猪只健康水平,降低饲料成本,增加经济效益。

关键词：低蛋白质发酵菜籽粕发酵白酒糟生长猪生长性能血清指标经济效益

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