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Neuroinflammation revisited through the microglial lens

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Neural Regeneration Research 2025年第7期20卷 1989-1990页

作者： Renato Socodato João b.Relvas Institute of Research and Innovation in Health(i3S)and Institute for Molecular and Cell biology(IbMC) University of PortoPortoPortugal Department of biomedicine Faculty of Medicine of the University of Porto(FMUP)PortoPortugal

Neuroimmunology is emerging as a pivotal field,shedding light on the intricate dialogues between the central nervous system(CNS)and the immune *** exploration is particularly significant in understanding microglia,the CNS’s innate immune cells,beyond the conventional conflation of“neuroinflammation”and“microglial activation.”This conflation has clouded the true complexity of these processes,potentially stalling scientific progress and the development of new *** challenge the long-standing perspectives that have oversimplified these interactions,advocating for a deeper exploration of the dynamic relationship between neuroinflammation and microglial *** dissecting specific molecular pathways,we aim to illuminate their elaborate roles in neuroinflammatory responses,especially in the context of Alzheimer’s disease(AD).Here,neuroinflammation is not merely a passive observer or a direct antagonist but a complex agent in the disease’s *** article calls for a significant paradigm shift towards an integrative,multi-omics approach to *** such a comprehensive framework is crucial for advancing our understanding of neuroinflammatory conditions and paving the way for targeted therapeutic strategies for brain diseases.

关键词： inflammation simplified activation

Piling up multidecker pyrgos[n]cages as antibacterial materials

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Science China Materials 2025年第01期 314-316页

作者： Miguel A.Liuzzi-Vaamonde Jackson b.Lancaster Samantha A.Mason Yuanning Feng Department of Chemistry and biochemistry The University of Oklahoma

The development of antibiotics is regarded as one of the most significant scientific advances in modern medicine. before the commercialization of antibiotics, infectious diseases were catastrophic throughout history [1]. Penicillin was used to treat serious infections in the 1940s, but unfortunately, with the introduction of antibiotics came the emergence of antibiotic resistance [2,3]. Evolved and adapted methicillin-resistant Staphylococcus aureus (MRSA) strains are presently impacting community and healthcare systems across the globe [4].

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A Comprehensive Survey on Federated Learning Applications in Computational Mental Healthcare

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Computer Modeling in Engineering & Sciences 2025年第1期142卷 49-90页

作者： Vajratiya Vajrobol Geetika Jain Saxena Amit Pundir Sanjeev Singh Akshat Gaurav Savi bansal Razaz Waheeb Attar Mosiur Rahman brij b.Gupta Institute of Informatics and Communication University of DelhiDelhi110021India Maharaja Agrasen College University of DelhiDelhi110096India Computer Engineering Ronin InstituteMontclairNJ 07043USA Department of Research and Innovation Insights2TechinfoJaipur302001India University Centre for Research and Development(UCRD) Chandigarh UniversityChandigarh140413India Management Department College of Business AdministrationPrincess Nourah bint Abdulrahman UniversityRiyadh11671Saudi Arabia CCRI&Department of Computer Science and Information Engineering Asia UniversityTaichung413Taiwan Symbiosis Centre for Information Technology(SCIT) Symbiosis International UniversityPune411057India Center for Interdisciplinary Research University of Petroleum and Energy Studies(UPES)Dehradun248007India

Mental health is a significant issue worldwide,and the utilization of technology to assist mental health has seen a growing *** aims to alleviate the workload on healthcare professionals and aid *** applications have been developed to support the challenges in intelligent healthcare ***,because mental health data is sensitive,privacy concerns have *** learning has gotten some *** research reviews the studies on federated learning and mental health related to solving the issue of intelligent healthcare *** explores various dimensions of federated learning in mental health,such as datasets(their types and sources),applications categorized based on mental health symptoms,federated mental health frameworks,federated machine learning,federated deep learning,and the benefits of federated learning in mental health *** research conducts surveys to evaluate the current state of mental health applications,mainly focusing on the role of Federated Learning(FL)and related privacy and data security *** survey provides valuable insights into how these applications are emerging and evolving,specifically emphasizing FL’s impact.

关键词： Depression emotional recognition intelligent healthcare systems mental health federated learning stress detection sleep behaviour

Nano-Enhanced Dairy Scum biodiesel blends:Unleashing the Power of Aluminium Oxide for Sustainable and Efficient Engine Performance

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Journal of Thermal Science 2025年第1期 283-302页

作者： Veeranna MODI Prasad b.RAMPURE Sunil Kumar SHETTY Madeva NAGARAL Channa Keshava NAIK N Johar MGM Muhammad Irsyad AbDULLAH Abdullah I.AL-MANSOUR Shamshad ALAM KLE College of Engineering and Technology ChikodiVisvesvaraya Technological University Nitte (Deemed to be University) NMAM Institute of Technology (NMAMIT)Department of Mechanical Engineering Aircraft Research and Design Centre HAL Department of Mechanical Engineering BGS College of Engineering and TechnologyBengaluruAffiliated to Visvesvaraya Technological University Management and Science University Department of Civil Engineering College of EngineeringKing Saud University

This study investigates the effect of aluminium oxide nanoparticlesaddition to biodiesel blends made from dairy milk scum on performance and combustion characteristics of the diesel *** dispersion of Al2O3nanoparticles in b20 blends at different concentrations was done with the help of *** number of blends were prepared for the *** Machine learning algorithms(Random Forest（RF）and Catboost) was used for the *** results show that in comparison to biodiesel blends without nanoparticles,the kinematic viscosity and density is higher for fuel blends with *** these Fuel blends have higher calorific *** blends exhibited reduced brake Specific Fuel Consumption（bSFC） of2.85% than the blends without nano particles(Dairy Scum Methyl Ester biodiesel 20%+Neat Diesel 80%（in volume）,DSMEb20),57.14% less CO,40.8% less hydrocarbon,and increased NOxemissions compared to conventional diesel,contributing to the development of environmentally friendly and renewable biofuel blends with *** b20NP30 is the optimal blend for performance and emission *** study concludes with findings on enhanced brake Thermal Efficiency（bTE） of 26.29% in 3×10-5（in volume） Al2O3nanoparticle-blended DSME b20 and other DSME b20 fuel blends,emphasizing the importance of optimal nanoparticle *** correlation matrix shows how engine load,efficiency measures（bTE,bSFC）,and emissions（CO,CO2,NOx,Smoke） are connected in complex *** results help us understand the complicated dynamics of engine performance and emission characteristics ***'s diagram for bTE and bSFC shows that Catboost-based bTE models perform superior to RF-based models during the training as well as testing *** results were obtained for CO and CO2emission results.

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述评：工艺水系统中的微生物控制

水处理信息报导 2002年第3期 7-12页

作者： RICHARDW.lutey 纪永亮

评述了近年来运行和环境方面的变化对工艺水系统中微生物控制技术产生的影响。使用非传统补充水源带来的影响和环境服务人员的重要性是相互关联的。他们需要评价现有的技术对目前和未来的微生物繁殖、腐蚀、结垢和污垢方面的控制能力。... 详细信息

评述了近年来运行和环境方面的变化对工艺水系统中微生物控制技术产生的影响。使用非传统补充水源带来的影响和环境服务人员的重要性是相互关联的。他们需要评价现有的技术对目前和未来的微生物繁殖、腐蚀、结垢和污垢方面的控制能力。讨论了当前的技术能否满足目前和今后在微生物控制方面的挑战。

关键词：述评工艺水系统微生物控制冷却水系统工业水处理

Corrosion by a Heavy Metal Oxide Glass

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Journal of Materials Science & Technology 2005年第2期21卷 243-245页

作者： b.b.Rana Department of Engineering Materials University of Sheffield Sheffield S1 4DU UK PCSIR Laboratories Complex LahorePakistan

Melts of lead bismuth gallate compositions are highly corrosive and attack on crucibles of different materials. In the present study, corrosion by a base glass (50PbO-30bi2O3-20Ga2O3 in mole fraction) melted using different crucibles and the effect on UV-VIS and IR edges were studied. by melting the base glass in platinum/2% rhodium, gold zirconia and alumina crucibles showed less effect on the IR edge and therefore shifted the infrared edge to longer wavelength, whereas silica crucible contaminated the glass, causing a severe deterioration in the infrared and hence shifted infrared edge to much shorter wavelength. In the UV-VIS region, base glass melted in platinum/2% rhodium crucible shifted the edge to the longest wavelength whereas silica crucible shifted the edge to shorter wavelength. The contaminants from gold, zirconia and alumina crucibles caused the UV-VIS edge of the base glass to lie between the two extremes of Pt/2% Rh and SiO2 crucibles. The glasses melted in above mentioned crucibles were also characterized with inductively coupled plasma spectroscopy (ICP) analysis to measure the level of contamination from the crucibles. Depending upon crucible used, the colors of glasses obtained ranged from red to yellow.

关键词： Oxide glass Corrosion Crucible

Nonsmooth Semi-Infinite Minmax Programming Involving Generalized(Φ, ρ)-Invexity

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Journal of Systems Science & Complexity 2015年第4期28卷 857-875页

作者： UPADHYAY b b MISHRA S K Department of basic Sciences & Humanities National Institute of Technology

This paper introduces some new generalizations of the concept of （~, p）-invexity for non- differentiable locally Lipschitz functions using the tools of Clarke subdifferential. These functions are used to derive the necessary and sufficient optimality conditions for a class of nonsmooth semi-infinite minmax programming problems, where set of restrictions are indexed in a compact set. Utilizing the sufficient optimality conditions, the authors formulate three types of dual models and establish weak and strong duality results. The results of the paper extend and unify naturally some earlier results from the literature.

关键词： Duality, generalized invexity locally Lipschitz functions, minmax programming, semi-infinite programming.

Investigation of nanocrystalline structure in selected carbonaceous materials

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International Journal of Minerals,Metallurgy and Materials 2014年第9期21卷 940-946页

作者： Manoj b Department of Physics Christ University

The structural parameters of nine Indian coals were determined by X-ray diffraction （XRD） and Kaman spectroscopy. The study revealed that the coals contain crystalline carbon of turbostratic structure with amorphous carbon. The stacking height （Lc） and interlayer spacing （rico2） of the crystallite structure of the coals ranged from 1.986 to 2.373 nm and from 0.334 to 0.340 nm, respectively. The degree of graphitization was calculated to range from 42% to 99%, thereby confirming the ordering of the carbon layers with the increase in coal rank. An exponential correlation was observed among the aromaticity （fa）, the lateral size （La）, and the rank （I20/I26）, suggesting that the coal crystallites are nanocrystalline in nature. A very strong correlation was observed between the structural parameters （fa, d002, Lc, the H/C ratio, and I20/I26）, the volatile matter content, and the elemental carbon content, indicating the structures of coals are controlled by the degree of contact metamorphism. The Raman spectra exhibited two prominent bands： the graphitic band （G） and the fn＇st-order characteristic defect band （D）. The deconvolufion resulted in five peaks： G, D1, D2, D3, and D4. The intense D1 band, which appeared at -1350 cm^-1, corresponds to a lattice vibration mode with Alg symmetry. The D2 mode, which appeared at -1610 cm^-1, arises from the structural disorder as a shoulder on the G band.

关键词： nanocrystals graphitization aromaticity carbonaceous materials

Rethinking the solar flare paradigm

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Plasma Science and Technology 2018年第7期20卷 15-21页

作者： d b melrose SIfA School of PhysicsThe University of SydneyNSW 2006Australi

It is widely accepted that solar flares involve release of magnetic energy stored in the solar corona above an active region, but existing models do not include the explicitly time-dependent electrodynamics needed to describe such energy release. A flare paradigm is discussed that includes the electromotive force （EMF） as the driver of the flare, and the flare-associated current that links different regions where magnetic reconnection, electron acceleration, the acceleration of mass motions and current closure occur. The EMF becomes localized across regions where energy conversion occurs, and is involved in energy propagation between these regions.

关键词： solar flares electrodynamics time-dependence