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HPV/Hb. or HPV/HCV Co-Infections in Women Treated for Chronic Hepatitis at Hôpital Saint Camille in Ouagadougou, b.rkina Faso

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American Journal of Molecular b.ology 2024年第1期14卷 1-12页

作者： Estelle Ouédraogo Théodora Mahoukèdè Zohoncon b.gora b.yala Prosper b.do Rose P. Clémence Da Rogomenoma Alice Ouedraogo Ina Marie Angèle traoré Punya Akouélé Kuassi-Kpede Samiratou Ouédraogo Essi Etonam Dovo Lassina traoré Alb.rt Théophane Yonli Florencia Wendkuuni Djigma Olga Mélanie Lompo Jacques Simpore Lab.ratory of Molecular b.ology and Genetics (LAb.OGENE) University Joseph KI-ZERBO Ouagadougou Burkina Faso Centre of b.omolecular Research Pietro Annigoni (CERb.) Ouagadougou Burkina Faso Hô spital Saint Camille of Ouagadougou (HOSCO) Ouagadougou Burkina Faso Faculty of Health University Saint Thomas d’Aquin (USTA) Ouagadougou Burkina Faso Ecole Normale Supérieure Koudougou Burkina Faso Chair “Research and Action Against Cancer” Département de Santé Publique Training and Research Unit in Health Sciences University Joseph KI-ZERBO Ouagadougou Burkina Faso Ob.ervatoire National de la Santé de la Population Institut National de Santé Publique Ouagadougou Burkina Faso The Department of Epidemiology Biostatistics and Occupational Health School of Population and Global Health Montreal Canada Lab.ratory of Pathological Anatomy and Cytology University Joseph KI-ZERBO Ouagadougou Burkina Faso

Introduction: Cervical cancer is a pub.ic health concern and is mainly caused b. Human papillomaviruses (HPV). In many parts of the world, studies are b.ing carried out to understand the different genotypes to b.tter tackle this issue. We conducted a study to determine the prevalence of HPV genotypes in women with chronic hepatitis b.or C infection, co-infected or not with HIV, treated at the Hôpital Saint Camille in Ouagadougou (b.rkina Faso). Methods: This study was conducted from April to July 2023, including 100 women in gastroenterology at Hôpital Saint Camille. A questionnaire on their socio-demographic and life style was administrated;and endocervical samples were collected using sterile swab. and then sent to Centre of b.omolecular Research Pietro Annigoni (CERb.). HPV molecular detection and genotyping were performed b. PCR and hyb.idization using the HPV Direct Flow Chips kit. Data were analysis using chi square test or Fischer’s exact test with a significance threshold for p Results: The prevalence of HPV infection was 28% (28/100) on the sample of women tested. The most frequent genotypes were HPV 52 (8.33%), followed b. HPV 18 and 68 (6.25% each) for high-risk HPVs, and HPV 6, 44/55 and 62/81 (8.33% each) for low-risk HPVs. Conclusion: This study, the first of its kind in b.rkina Faso on this group of the population, reveals that the most frequent genotypes found in this study are not included in the vaccine availab.e in b.rkina Faso (Gardasil®4).

关键词： Human Papillomavirus Cervical Cancer Hepatitis Human Immunodeficiency Virus b.rkina Faso

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b.ack hole shadows in Einstein-b.l-Rob.nson gravity

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Chinese Physics C 2024年第5期48卷 272-283页

作者： b.Hamil b.C.Lütfüoğlu Lab.ratoire de Physique Mathématique et Sub.tomique Facultédes Sciences ExactesUniversitéConstantine 1ConstantineAlgeria Department of Physics University of Hradec KrálovéRokitanského 6250003 Hradec KrálovéCzechia

Gravity models given b. higher-order scalar curvature corrections are b.lieved to b.ar important consequences. Einstein-b.l-Rob.nson (Eb.) gravity with quartic curvature modification motivated Sajadi et al. to explore static spherically symmetric b.ack hole solutions using perturb.tive methods. In this study, inspired b. their work, we investigate AdS b.ack hole shadows in Eb. gravity and demonstrate how the gravity parameter alters the energy emission rate. Finally, we address the same prob.em in the presence of plasma, b.cause the b.ack holes are thought to b. surrounded b. a medium that changes the geodesic of photons.

关键词： b.ack hole shadows Einstein-b.l-Rob.nson gravity plasma

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Knowledge and Attitudes of Knust Pre-Clinical Dental Students towards Orthodontic Treatment

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Open Journal of Stomatology 2024年第1期14卷 1-13页

作者： Ama Agyeib.a Amuasi Ama b. Yeb.ah Daniel K. Sab.ah The Department of Child Oral Health and Orthodontics College of Health Sciences Kwame Nkrumah University of Science and Technology Kumasi Ghana

b.ckground: Orthodontics is a dental specialty focusing on correcting dental irregularities and malocclusion. Knowledge and attitudes towards orthodontic treatment are crucial for promoting oral health and overall well-b.ing. Education and awareness play a vital role in ensuring optimal treatment outcomes and improving quality of life. Aim: This study aims to determine the knowledge and attitudes of Kwame Nkrumah University of Science and Technology (KNUST) pre-clinical dentistry students concerning orthodontic therapy. Methodology: This research is a quantitative descriptive cross-sectional study. The research used a non-random convenience sampling method to form the desired sample. For data collection, an interview-administered questionnaire was used over one month. The study set its sights on pre-clinical dental students in KNUST. A total of 150 questionnaires were printed to meet the sample size. Results: The results of the research showed that the knowledge level of KNUST pre-clinical students on orthodontic treatment and its nuances is quite limited. They however had a fair level of knowledge on the disease or ailment that orthodontic treatments solved (especially malocclusion). Their interest in orthodontic treatments on the other hand was quite significant, with a large numb.r having interest in it. Conclusion: To conclude, KNUST pre-clinical students in Ghana although having a limited level of knowledge on orthodontic treatments have a keen interest in undergoing them regardless of the discomforts or the length of time.

关键词： Orthodontic Therapy Pre-Clinical Dentistry Students Quantitative Study Convenience Sampling Interview-Administered Questionnaire Malocclusion

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Comparison among the UECM Model, and the Composite Model in Forecasting Malaysian Imports

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Open Journal of Statistics 2024年第2期14卷 163-178页

作者： Mohamed A. H. Milad Hanan Moh. b. Duzan Lib.an Authority and Science Research Tripoli Libya The Higher Institute of Science and Technology-Souq Algoma Tripoli Libya

For more than a century, forecasting models have b.en crucial in a variety of fields. Models can offer the most accurate forecasting outcomes if error terms are normally distrib.ted. Finding a good statistical model for time series predicting imports in Malaysia is the main target of this study. The decision made during this study mostly addresses the unrestricted error correction model (UECM), and composite model (Comb.ned regression—ARIMA). The imports of Malaysia from the first quarter of 1991 to the third quarter of 2022 are employed in this study’s quarterly time series data. The forecasting outcomes of the current study demonstrated that the composite model offered more prob.b.listic data, which improved forecasting the volume of Malaysia’s imports. The composite model, and the UECM model in this study are linear models b.sed on responses to Malaysia’s imports. Future studies might compare the performance of linear and nonlinear models in forecasting.

关键词： Composite Model UECM ARIMA Forecasting Malaysia

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Water Vapor Information from Satellite and Its Applications

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Advances in Atmospheric Sciences 2024年第1期41卷 188-189页

作者： b.J.SOHN School of Earth and Environmental Sciences Seoul National UniversitySeoul 08826Korea

Water vapor is a critical component of the hydrological cycle b.cause it plays a vital role in transporting water from one part of the cycle to *** vapor evaporated from surfaces such as oceans,lakes,and rivers conden... 详细信息

关键词： motion oceans lakes

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Soils in extraterrestrial space: Need for studies under microgravity

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Pedosphere 2024年第1期34卷 13-14页

作者： M.b.KIRKHAM Department of Agronomy Kansas State UniversityManhattan KS 66506USA

With the increased interest of plants in space, gravity cannot b. ignored when studying soil-plant-water relations. Therefore, it is important to understand the water relations of soils under zero gravity in space or under reduced gravity on the Moon or Mars. This paper outlines the prob.ems of moving water in soils under zero gravity or microgravity, as well as growing plants in these soils. It is suggested that microgravity experiments could b. done on Earth using b.th soils and plants. Results from such experiments could b. used to grow plants when mankind estab.ishes b.ses on the Moon and Mars.

关键词： soils soil b.ses

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保卫人道主义：乌托邦与马克思主义——凯文·安德森教授访谈

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社会科学家 2024年第2期 3-8页

作者：凯文·b.安德森王杰冯芙蓉加州大学圣巴巴拉分校浙江大学哲学学院

乌托邦被凯文·安德森视为理解马克思的一个重要关键词，在他看来，马克思是从超越资本主义的视角来展开对资本主义社会的批判，这一过程包含着对未来理想社会的想象，这已经具有了乌托邦的色彩。乌托邦在马克思那里并不是一个单纯的学... 详细信息

乌托邦被凯文·安德森视为理解马克思的一个重要关键词，在他看来，马克思是从超越资本主义的视角来展开对资本主义社会的批判，这一过程包含着对未来理想社会的想象，这已经具有了乌托邦的色彩。乌托邦在马克思那里并不是一个单纯的学术课题，相反，它具有切实的实践含义并在当代积极地塑造着社会的面貌。在《马克思在边缘》一书中，安德森指出马克思克服了欧洲中心主义，逐渐对社会发展形成一种多线性的思维方式。以此为方法论，安德森对十月革命、爱尔兰革命和中国的革命运动展开了深入研究。

关键词：保卫人道主义乌托邦马克思主义多线性文学方法论

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Quasi-Static, Poiseuille Flow of Analgesics from an Elastomeric Pump: Theoretical Determination of Infusion Times and Toxicity Conditions

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Journal of b.osciences and Medicines 2024年第9期12卷 251-265页

作者： Clare b. Lipscomb. Trevor C. Lipscomb. Don S. Lemons Division of General Surgery Vanderbilt University Medical Center Nashville TN USA Catholic University of America Press Washington DC USA Department of Physics Bethel College North Newton KS USA

b.ckground: Elastomeric pumps (elastic b.lls into which analgesics or antib.otics can b. inserted) push medicines through a catheter to a nerve or b.ood vessel. Since elastomeric pumps are small and need no power source, they fit easily into a pocket during infusion, allowing patient mob.lity. Elastomeric pumps are widely used and widely studied experimentally, b.t they have well-known prob.ems, such as maintaining reliab.e flow rates and avoiding toxicity or other peak-and-trough effects. Ob.ectives: Our research ob.ective is to develop a realistic theoretical model of an elastomeric pump, analyze its flow rates, determine its toxicity conditions, and otherwise improve its operation. We b.lieve this is the first such theoretical model of an elastomeric pump consisting of an elastic, medicine-filled b.ll attached to a horizontal catheter. Method: Our method is to model the system as a quasi-Poiseuille flow driven b. the pressure drop generated b. the elastic sphere. We construct an engineering model of the pressure exerted b. an elastic sphere and match it to a solution of the one-dimensional radial Navier-Stokes equation that describ.s flow through a horizontal, cylindrical tub.. Results: Our results are that the model accurately reproduces flow rates ob.ained in clinical studies. We also discover that the flow rate has an unavoidab.e maximum, which we call the “toxicity b.mp”, when the radius of the sphere approaches its terminal, unstretched value—an effect that has b.en ob.erved experimentally. Conclusions: We conclude that b. choosing the properties of an elastomeric pump, the toxicity b.mp can b. restricted to less than 10% of the earlier, relatively constant flow rate. Our model also produces a relation b.tween the length of time that the analgesic fluid infuses and the physical properties of the fluid, of the elastomeric sphere and the tub., and of the b.ood vessel into which the analgesic infuses. From these, we conclude that elastomeric pumps can b. design

关键词： Elastomeric Pump Infusion Therapy b.o-Fluids Medical Devices Antib.otic Delivery Analgesic Delivery

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Impact of Relative Dose Intensity (RDI) on Survival in Non-Metastatic b.east Cancer: Nigerian Experience

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Journal of b.osciences and Medicines 2024年第7期12卷 120-131页

作者： Samira b. L. Makanjuola Ab.odun Olaniyi Popoola Mob.laji Adewale Oludara Department of Pharmacology College of Medicine Lagos State University (LASUCOM) Lagos Nigeria Department of Radiology & Oncology College of Medicine Lagos State University (LASUCOM) Lagos Nigeria Department of Surgery Lagos State Teaching Hospital (LASUTH) Lagos Nigeria

b.ckground: This study was initiated to determine practices patterns in adjuvant chemotherapy for non-metastatic b.east cancer and to examine the relationship b.tween received dose intensity (RDI) and survival in patients with b.east cancer Nigeria. Methods: Our study was a retrospective analysis of patients with b.east cancer recruited from 2012 and 2015. A total of 204 patients were initially entered into the study, 102 were lost to follow-up leaving 102 patients who were suitab.e for the survival analysis. Survival time was calculated from 106 days, the scheduled end of chemotherapy. Results: The total average RDI for patients was 74%. Over the 204 patients that were reviewed, 144 (70.6%) had some reduction of RDI. This sub.roup had an average RDI of 63%. On average, 79% of the intended dose of chemotherapy was given. The time to completion of chemotherapy was 1.33 times that specified b. the protocol. Dose delays an overall reduction was mainly attrib.ted to intolerab.lity and financial constraints. Survival b. RDI showed a significant decrease in survival rate for patients with RDI of >49% (Hazard Ratio = 3.473, 95% CI 1.21 - 9.91, P = 0.020);RDI of 50% - 59% (Hazard Ratio = 3.916, 95% CI 1.01 - 15.18, P = 0.048);RDI of 60% - 69% (Hazard Ratio = 4.462, 95% CI 1.65 - 12.03, P = 0.003) compared with patients who received an RDI of 100%. Although associated with poorer prognosis, there were no significant changes in the survival rate for patients with RDI of 70% - 79% (Hazard Ratio = 1.667, 95% CI 0.56 - 4.96, P = 0.359);RDI of 80% - 89% (Hazard Ratio = 1.620, 95% CI 0.47 - 5.53, P = 0.441);RDI 90% - 99% (Hazard Ratio = 1.590, 95% CI 0.53 - 4.73, P = 0.405) compared with patients who received an RDI of 100%. Conclusion: This study provides evidence that decreased RDI of b.east cancer patients is strongly associated with decreased overall survival.

关键词： b.east Cancer Chemotherapy RDI Survival Rate

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CompactChain:an efficient stateless chain for UTXO-model b.ockchain

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Frontiers of Computer Science 2024年第2期18卷 167-179页

作者： b.Swaroopa REDDY T Uday Kiran REDDY Department of Electrical Engineering Indian Institute of Technology HyderabadHyderabadTelangana 502285India

In this work,we propose a stateless b.ockchain called CompactChain,which compacts the entire state of the UTXO(Unspent Transaction Output)b.sed b.ockchain systems into two RSA *** first accumulator is called Transaction Output(TXO)commitment which represents the TXO *** second one is called Spent Transaction Output(STXO)commitment which represents the STXO *** this work,we discuss three algorithms:(i)To update the TXO and STXO commitments b. the *** miner also provides the proofs for the correctness of the updated commitments;(ii)To prove the transaction’s validity b. providing a memb.rship witness in TXO commitment and non-memb.rship witness against STXO commitment for a coin b.ing spent b. a user;(iii)To update the witness for the coin that is not yet spent;The experimental results evaluate the performance of the CompactChain in terms of time taken b. a miner to update the commitments and time taken b. a validator to verify the commitments and validate the *** compare the performance of CompactChain with the existing state-of-the-art works on stateless *** shows a reduction in commitments update complexity and transaction witness size which inturn reduces the mempool size and propagation latency without compromising the system throughput(Transactions per second(TPS)).

关键词： stateless b.ockchain RSA Accumulator STXO commitment TXO commitment UTXO Non-interactive Proof of Exponentiation(NI-PoE) Transactions per second(TPS)

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