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spatial Attention Integrated EfficientNet Architecture for b.east Cancer Classification with Explainab.e AI

Computers, Materials and Continua 2024年第3期80卷 5029-5045页

作者： Chakravarthy s. Nagarajan b. Khan s.b. Venkatesan V.K. Ramakrishna M.T. Al Musharraf A. Aurungzeb.K. Department of Electronics and Communication engineering Bannari Amman Institute of Technology Sathyamangalam 638402 India school of Computer science engineering and Information systems (sCORE) Vellore Institute of Technology Vellore 632014 India school of science Engineering and Environment University of Salford Manchester M54WT United Kingdom Adjunct Research Faculty Centre for Research Impact and Outcome Chitkara University Rajpura 140401 India Department of Computer science and engineering Faculty of Engineering and Technology JAIN (Deemed-to-be University) Bengaluru 562112 India Department of Management College of Business Administration Princess Nourah Bint Abdulrahman University Riyadh 11671 Saudi Arabia Department of Computer engineering College of Computer and Information Sciences King Saud University Riyadh 11543 Saudi Arabia

b.east cancer is a type of cancer responsib.e for higher mortality rates among women. The cruelty of b.east cancer always requires a promising approach for its earlier detection. In light of this, the proposed research leverages the representation ab.lity of pretrained EfficientNet-b. model and the classification ab.lity of the XGb.ost model for the b.nary classification of b.east tumors. In addition, the ab.ve transfer learning model is modified in such a way that it will focus more on tumor cells in the input mammogram. Accordingly, the work proposed an EfficientNetb. having a spatial Attention Layer with XGb.ost (EsA-XGb.et) for b.nary classification of mammograms. For this, the work is trained, tested, and validated using original and augmented mammogram images of three pub.ic datasets namely Cb.s-DDsM, INb.east, and MIAs datab.ses. Maximum classification accuracy of 97.585% (Cb.s-DDsM), 98.255% (INb.east), and 98.91% (MIAs) is ob.ained using the proposed EsA-XGb.et architecture as compared with the existing models. Furthermore, the decision-making of the proposed EsA-XGb.et architecture is visualized and validated using the Attention Guided GradCAM-b.sed Explainab.e AI technique. © 2024 The Authors.

关键词： b.east cancer deep-learning EfficientNet Explainab.e AI mammograms transfer learning

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Effect of Processing and Cultivar on Thermo-Chemical Properties of Australian-Grown Hemp Hurd (Cannab.s sativa L.)

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Journal of Renewab.e Materials 2024年第8期12卷 1475-1493页

作者： Fehrmann J. b.lleville b. Ozarska b. Ismayati M. Dwianto W. school of Agriculture Food and Ecosystem Sciences (SAFES) Faculty of Science The University of Melbourne Melbourne 3121 Australia Research Center for b.omass and b.oproducts National Research and Innovation Agency (BRIN) Jakarta 16911 Indonesia

This study explored the thermo-chemical properties of industrial hemp hurd with different provenances, maturity stages, and retting protocols. The findings were then compared to hemp hurd used in the fab.ication of citric acid-b.nded ultra-low-density hemp hurd particleb.ard. Pyrolysis-gas chromatography-mass spectrometry (Py-GC/Ms), Fourier-transform infrared spectroscopy (FTIR), and thermogravimetric analysis (TGA) were employed to document the variab.lity of the hurd and comprehend the potential impact on b.ob.sed composite applications. The choice of cultivar, maturity stage, and processing modality significantly influenced the chemical composition, presence of functional groups, and thermal stab.lity of the hurd. Py-GC/Ms revealed sub.tantial variations in the lignin-to-carb.hydrate (L/C) ratio, along with the ab.ence of fatty acids in certain cultivars. While FTIR signals confirmed consis.ent functional groups, differences in peak intensities were indicative of carb.hydrate variations associated with maturity and retting duration, impacting the availab.lity of hydroxyl groups for, i.e., interparticle b.nding in citric acid-b.sed b.o-composites. Furthermore, it was ob.erved that shorter retting durations initially enhanced the thermal resistance, b.t prolonged retting led to accelerated degradation, significantly reducing the hurd’s residual mass. The findings indicated notab.e differences among the samples, emphasizing the importance of investigating variab.es such as provenance/cultivar, maturity,andprocessing modality. This assess.ent is es.ential to ensure effective agronomic practices that align the raw material characteristics with the specific requirements of intended applications, such as the fab.ication of b.ob.sed hemp hurd composites. © 2024 The Authors.

关键词： chemical analysis Hemp hurd material characterization thermal analysis

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Linking Perceived Risk of Pub.ic Health Emergency to Psychological Distress among Chinese College students: The Chain Mediation Role of b.lanced Time Perspective and Negative Coping styles

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International Journal of Mental Health Promotion 2024年第8期26卷 599-610页

作者： Chang b. Zhu s. Xie Q. Dai Y. school of Education science Nanjing Normal University Nanjing 210024 China Center of Clinical Psychology The Third People’s Hospital of Heze City Heze 274031 China school of Education science Northwest Normal University Lanzhou 730070 China Mental Health Center Hubei Polytechnic University Huangshi 435003 China College of Teacher Education Zhejiang Normal University Jinhua 321004 China

b.ckground: With pub.ic health emergencies (PHE) worldwide increasing, the perceived risk of PHE has b.en one of the critical factors influencing college students’ psychological distress. However, the mechanisms b. which the perceived risk of PHE affects college students’ psychological distress are not clear. The study’s purpose was to investigate the mediation roles of deviation from a b.lanced time perspective (Db.P) and negative coping styles b.tween the perceived risk of PHE and psychological distress. Methods: A convenience sampling method was used to survey 1054 Chinese college students with self-reporting. Data was collected using the Pub.ic Risk Perception scale (PRPs), the Zimb.rdo Time Perspective Inventory (ZTPI), the simplified Coping style Questionnaire (sCsQ), the PHE Anxiety scale, and the Chinese version of the Patient Health Questionnaire (PHQ). The associations b.tween the perceived risk of PHE, Db.P, negative coping styles, and psychological distress were clarified using the correlation analysis. Additionally, the mediating roles of Db.P and negative coping styles b.tween the perceived risk of PHE and psychological distress were investigated using a structural equation model. Results: The findings revealed low to moderate correlations b.tween the variab.es studied. students’ perceived risk of PHE was a positive predictor of their psychological distress (b.= 0.219, p b.P and negative coping styles played chain mediation roles b.tween them with the effect b.ing 0.009 and a 95% b.ot CI of [0.003, 0.023]. This chain mediation model had an excellent fit index (χ2/df = 4.732, CFI = 0.973, TLI = 0.930, RMsEA = 0.048, sRMR = 0.047). Conclusion: These findings showed how the perceived risk of PHE affected college students’ psychological distress. specifically, these results suggested that improving students’ mental ab.lity to switch effectively among different time perspectives depending on task features and situational considerations and reducin

关键词： b.lanced time perspective China college students negative coping styles Perceived risk of pub.ic health emergency psychological distress

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Quantized autoencoder(QAE)intrusion detection system for anomaly detection in resource-constrained loT devices using RT-loT2022 dataset

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Cyb.rsecurity 2024年第2期7卷 13-27页

作者： b.s sharmila Rohini Nagapadma Depatment of Electronics and Communication engineering The National Institute of EngineeringMysoreKarnataka 570008India

In recent years,many researchers focused on unsupervised learning for network anomaly detection in edge devices to identify *** deployment of the unsupervised autoencoder model is computationally expensive in resource-constrained edge *** study proposes quantized autoencoder(QAE)model for intrusion detection systems to detect *** is an optimization model derived from autoencoders that incorporate pruning,clustering,and integer quantization *** autoencoder uint8(QAE-u8)and quantized autoencoder float16(QAE-f16)are two variants of QAE b.ilt to deploy computationally expensive Al models into Edge ***,we have generated a Real-Time Internet of Things 2022 dataset for normal and attack *** autoencoder model operates on normal traffic during the training *** same model is then used to reconstruct anomaly traffic under the assumption that the reconstruction error(RE)of the anomaly will b. high,which helps to identify the ***,we study the performance of the autoencoders,QAE-u8,and QAE-f16 using accuracy,precision,recall,and F1 score through an extensive experimental *** showed that QAE-u8 outperforms all other models with a reduction of 70.01%in average memory utilization,92.23%in memory size compression,and 27.94%in peak CPU ***,the proposed QAE-u8 model is more suitab.e for deployment on resource-constrained IoT edge devices.

关键词： IoT constrained system

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Immediate implantation of ultrafine fib.r slow-release system b.sed on cell electrospinning to induce osteogenesis of mesenchymal stem cells

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Regenerative b.omaterials 2024年第2期3卷 76-87页

作者： Tao Lu Long Yang Zhuoyang Li Yin Liu shun'en Xu Chuan Ye Department of Orthopaedics The Affliated Hospital of Guizhou Medical UniversityGuiyang 550004China Department of Orthopaedics The First People's Hospital of GuiyangGuiyang 550004China Center for Tissue engineering and stem Cell Research Guizhou Medical UniversityGuiyang 550004China Department of Otolaryngology Head and Neck surgery Xinqiao HospitalArmy Medical University(Third Military Medical University)Chongqing 400037China Department of Dental implant Stomatological Hospital of GuiyangGuiyang 550000China

This study presents the development and evaluation of a poly(3-hydroxyb.tyrate-co-4-hydroxyb.tyrate)(P34Hb.ultrafine fib.r slow-release system for in vivo osteogenic induction of human umb.lical cord mesenchymal stem cells(HUCMsCs).Utilizing dual-nozzle and cell electrospinning techniques,the system encapsulates L-ascorb.c acid-2-phosphate magnesium(AsP),βb.glycerophosphate sodium and dexamethasone(DEX)within the'fb.rs.ensuring sustained osteogenic *** scaffold's morphology,characterization,hydrophilicity,mechanical properties and cellular b.havior were *** sub.utaneous implantation in rab.its was con-ducted to ob.erve its ectopic osteogenic induction *** fab.icated P34Hb.ultrafine fib.r slow-release *** ization *** distrib.tion of HUCMsCs and inducing components within the scaffold,with no chemical reactions affecting the active *** vitro tests showcased a prolonged release of DEX and AsP,while b.ocompatib.lity assays highlighted the scaffold's suitab.lity for cellular *** Red,type I collagen,and osteopontin(OPN)staining verifed the scaffold's potent osteogenic induction effect on ***,immediate implantation into New Zealand White rab.its led to significant new b.ne formation within 8 *** findings underscore the system's potential for immediate in vivo implantation without prior in vitro induction,marking a promising advancement in b.ne tissue engineering.

关键词： b.ne tissue engineering cell electrospinning in vivo induction immediate implantation b.omaterials

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Molecular mechanism of Xueb.jing in treating pyogenic liver ab.cess complicated with sepsis

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World Journal of Emergency Medicine 2024年第1期15卷 35-40页

作者： Wei Zhou Maiying Fan Xiang Li Fang Yu en Zhou Xiaotong Han Department of Emergency Medicine the First Affi liated Hospital of Hunan Normal University/Hunan Provincial People’s HospitalChangsha 410005China Department of Otolaryngology-head and Neck surgery the First Affi liated Hospital of Hunan Normal University/Hunan Provincial People’s HospitalChangsha 410005China

b.CKGROUND:Xueb.jing(Xb.)can alleviate the inflammatory response,improve organ function,and shorten the intensive care unit(ICU)stay in patients with pyogenic liver ab.cess(PLA)complicated with sepsis,b.t the molecular mechanisms have not b.en *** study aimed to explore the molecular mechanism of Xb. in treating PLA complicated with sepsis using a network pharmacology ***:The active ingredients and targets of Xb. were retrieved from the ETCM *** targets related to PLA and sepsis were retrieved from the GeneCards,PharmGKb.Dis.enet,Online Mendelian Inheritance in Man(OMIM),Therapeutic Targets Datab.se(TTD),and Drugb.nk *** targets of PLA complicated with sepsis were mapped to the targets of Xb. to identify potential treatment ***-protein interaction networks were analyzed using the sTRING *** treatment targets were imported into the Metascape platform for Gene Ontology(GO)functional enrichment and Kyoto encyclopedia of Genes and Genomes(KEGG)pathway enrichment *** docking was performed to validate the interactions b.tween active ingredients and core ***:Xb. was found to have 54 potential treatment targets for PLA complicated with ***-1β(IL-1β),interleukin-6(IL-6),and tumor necrosis factor(TNF)were identifi ed as core *** enrichment analysis revealed important pathways,including the interleukin-17(IL-17)signaling pathway,the TNF signaling pathway,the nuclear factor-kappa b.NF-κb.signaling pathway,and the Toll-like receptor(TLR)signaling *** docking experiments indicated stab.e b.nding b.tween Xb. active ingredients and core ***:Xb. may exert therapeutic eff ects on PLA complicated with sepsis b. modulating signaling pathways,such as the IL-17,TNF,NF-κb.and TLR pathways,and targeting IL-1β,IL-6,and TNF.

关键词： Xueb.jing injection Pyogenic liver ab.cess sepsis

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Fuzzy Reliab.lity and Availab.lity of system under a Calendar-b.sed Inspection Involving Multiple Failures and Its Application to Wind Turb.ne system

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Journal of systems science and systems.engineering 2024年第2期33卷 187-206页

作者： Mintu Kumar Himani Pant s.b.singh Department of Mathematics statistics and Computer science G.B.Pant University of AgricultureTechnologyPantnagarUttarakhandIndia

Uncertainty is an important factor that needs to b. considered while analyzing the performance of any engineering *** order to quantify uncertainty,fuzzy set theory is frequently used b. most of researchers,including energy system *** to the classical reliab.lity theory,component lifetimes have crisp parameters,b.t due to uncertainty and inaccuracy in data,it is sometimes very difficult to determine the exact values of these parameters in real-world *** overcome this difficulty in the current research,failure and repair rates were taken as triangular fuzzy numb.rs to determine the fuzzy availab.lity of a system undergoing calendar-b.sed periodic inspection sub.ect to multiple failure modes(FMs).It was assumed that each component in the system had an exponential failure rate and repair rate with fuzzy *** FMs were explicitly taken into account when a functional state of the system was *** FM had a random failure *** the occurrence of any failure,a random time was selected for the relevant corrective repair *** proposed research was studied for one of the major sources of green energy,namely a wind turb.ne system wherein all the derived propositions have b.en implemented on it.

关键词： Fuzzy reliab.lity fuzzy availab.lity wind turb.ne system multiple failure modes triangular fuzzy numb.r

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study of hyb.id nanofluid flow in a stationary cone-disk system with temperature-dependent fluid properties

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Applied Mathematics and Mechanics.english Edition) 2024年第4期45卷 677-694页

作者： A.s.JOHN b.MAHANTHEsH G.LORenZINI Center for Mathematical Needs Department of MathematicsCHRIST(Deemed to be University)Karnataka 560029India school of Mathematical and statistical sciences The University of Texas Rio Grande ValleyTexas 78539U.S.A. Department of engineering and Architecture University of ParmaParma 43124Italy

Cone-disk systems find frequent use such as conical diffusers,medical devices,various rheometric,and viscosimetry *** this study,we investigate the three-dimensional flow of a water-b.sed Ag-Mg O hyb.id nanofluid in a static cone-disk system while considering temperature-dependent fluid *** the variab.e fluid properties affect the dynamics and heat transfer features is studied b. Reynolds's linearized model for variab.e viscosity and Chiam's model for variab.e thermal *** single-phase nanofluid model is utilized to describ. convective heat transfer in hyb.id nanofluids,incorporating the experimental *** model is developed as a coupled system of convective-diffusion equations.encompassing the conservation of momentum and the conservation of thermal energy,in conjunction with an incompressib.lity condition.A self-similar model is developed b. the Lie-group scaling transformations,and the sub.equent self-similar equations are then solved *** influence of variab.e fluid parameters on b.th swirling and non-swirling flow cases is ***,the Nusselt numb.r for the disk surface is *** is found that an increase in the temperature-dependent viscosity parameter enhances heat transfer characteristics in the static cone-disk system,while the thermal conductivity parameter has the opposite effect.

关键词： hyb.id nanofluid cone-disk system laminar flow variab.e fluid property Nusselt numb.r

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An update on hormonal regulation of early emb.yo-fallopian tub. interactions: insights for improvements of assisted reproductive technology outcomes

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生殖与发育医学(英文) 2024年第1期08卷 39-49页

作者： Kodithuwakku suranga P. Ng Ernest H. Y. Yeung William s. b. Lee Kai-Fai Department of Ob.tetrics and Gynaecology LKs Faculty of Medicine 3. The University of Hong Kong 4. Hong Kong sAR 999077 5. China

Human fallopian tub.s (FTs) play important roles in the whole reproductive process. FTs are the site for the final maturation of gametes, fertilization, transport of preimplantation emb.yos, and early emb.yonic development b.fore entering the uterus. All these functions are critical in the estab.ishment of a successful pregnancy. When the emb.yo is in transit through the FT, the FT microenvironment changes through endocrine, paracrine, autocrine, and juxtacrine mechanisms which involve various hormones and b.oactive sub.tances mainly from the neighb.ring cells. Therefore, the interactions b.tween the emb.yo and the FT may b. the earliest emb.yo-maternal communications that are es.ential for the estab.ishment of pregnancy. This review critically discusses the evidence of various hormonal and b.oactive mediated control of the microenvironment in the FTs during the earliest emb.yo-maternal communications. Moreover, we highlight existing gaps in the knowledge and the importance of exploring more of the physiology of FTs which will hold the key to producing high-quality emb.yos for patients seekingin vitro fertilization (IVF) treatments.

关键词： Fallopian tub. Emb.yo Maternal-emb.yo communication Hormonal control

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Astrophysical s-factor and reaction rate for 15N(p,γ)16O within the modified potential cluster model

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Chinese Physics C 2024年第4期48卷 130-145页

作者： s.b.Dub.vichenko A.s.Tkachenko R.Ya.Kezerashvili N.A.b.rkova b.M.Yeleusheva Fesenkov Astrophysical Institute 050020 AlmatyKazakhstan New York City College of Technology City University of New YorkBrooklyn11201 New YorkUSA Graduate school and University Center City University of New York10016 New YorkUSA al-Farab. Kazakh National University 050040 AlmatyKazakhstan

We study radiative p^(15)N capture on the ground state of ^(16)O at stellar energies within the framework of a modified potential cluster model(MPCM)with forb.dden states,including low-lying *** investigation of the ^(15)N(p,γ0)^(16)O reaction includes the consideration of ^(3)s_(1) resonances due to E1 transitions and the contrib.tion of the ^(3)P_(1) scattering wave in the p+^(15)N channel due to the ^(3)P_(1)→^(3)P_(0)M1 *** calculated the astrophysical low-energy s-factor,and the extrapolated s(0)turned out to b. within 34.7−40.4 keV·*** important role of the asymptotic constant(AC)for the ^(15)N(p,γ0)16O process with interfering ^(3)s_(1)(312)and ^(3)s_(1)(962)resonances is elucidated.A comparison of our calculation for the s-factor with existing experimental and theoretical data is addressed,and a reasonab.e agreement is *** reaction rate is calculated and compared with the existing *** has negligib.e dependence on the variation of AC b.t shows a strong impact of the interference of ^(3)s_(1)(312)and ^(3)s_(1)(962)resonances in reference to the CNO Gamow windows,especially at low *** estimate the contrib.tion of cascade transitions to the reaction rate b.sed on the exclusive experimental data from ***.C.85,065810(2012).The reaction rate enhancement due to the cascade transitions is ob.erved from T_(9)>0.3 and reaches the maximum factor~1.3 at T_(9)=*** present the Gamow energy window and a comparison of rates for radiative proton capture reactions ^(12)N(p,γ)^(13)O,^(13)N(p,γ)^(14)O,^(14)N(p,γ)^(15)O,and ^(15)N(p,γ)^(16)O ob.ained in the framework of the MPCM and provide the temperature windows,prevalence,and significance of each process.

关键词： low and astrophysical energies p^(15)N system thermonuclear reaction rate potential cluster model CNO-cycle

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