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Mechanical Properties of Living Adherent Cells :Relationship with Structure and Function

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生物医学工程学杂志 2005年第S1期22卷 9-10页

作者： R. FODIL S. Féréol E. PLANUS V.M. LAURENT b. louis D. ISAb.Y Inserm UMR 651 Fonctions Cellulaire et Moléculaire de l'Appareil Respiratoire et des Vaisseaux Equipe Biomécanique Cellulaire et Respiratoire Faculté de Médecine Créteil 94 010 FranceInserm UMR 651 Fonctions Cellulaire et Moléculaire de l'Appareil Respiratoire et des Vaisseaux Equipe Biomécanique Cellulaire et Respiratoire Faculté de Médecine Créteil 94 010 FranceInserm UMR 651 Fonctions Cellulaire et Moléculaire de l'Appareil Respiratoire et des Vaisseaux Equipe Biomécanique Cellulaire et Respiratoire Faculté de Médecine Créteil 94 010 FranceInserm UMR 651 Fonctions Cellulaire et Moléculaire de l'Appareil Respiratoire et des Vaisseaux Equipe Biomécanique Cellulaire et Respiratoire Faculté de Médecine Créteil 94 010 FranceInserm UMR 651 Fonctions Cellulaire et Moléculaire de l'Appareil Respiratoire et des Vaisseaux Equipe Biomécanique Cellulaire et Respiratoire Faculté de Médecine Créteil 94 010 FranceInserm UMR 651 Fonctions Cellulaire et Moléculaire de l'Appareil Respiratoire et des Vaisseaux Equipe Biomécanique Cellulaire et Respiratoire Faculté de Médecine Créteil 94 010 France

Nearest Neighb.r Sampling of Point Sets Using Rays

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Communications on Applied Mathematics and Computation 2024年第2期6卷 1131-1174页

作者： Liangchen Liu louis Ly Colin b.Macdonald Richard Tsai Department of Mathematics The University of Texas at Austin2515 SpeedwayAustinTX 78712USA Oden Institute for Computational Engineering and Sciences The University of Texas at Austin201 E24th StAustinTX 78712USA Department of Mathematics University of British Columbia1984 Mathematics RdVancouverBCV6T1Z2Canada

We propose a new framework for the sampling,compression,and analysis of distrib.tions of point sets and other geometric ob.ects emb.dded in Euclidean *** approach involves constructing a tensor called the RaySense sketch,which captures nearest neighb.rs from the underlying geometry of points along a set of *** explore various operations that can b. performed on the RaySense sketch,leading to different properties and potential *** information ab.ut the data set can b. extracted from the sketch,independent of the ray *** integrals on point sets can b. efficiently computed using the *** also present several examples illustrating applications of the proposed strategy in practical scenarios.

关键词： Point clouds Sampling Classification Registration Deep learning Voronoi cell analysis

Management of Testicular Cancers in b.azzaville

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Open Journal of Urology 2024年第5期14卷 324-332页

作者： Roland b.rtile b.nga-Mouss Yanick Dimi Nyanga b.ice Nkoua Epala Armel Melvin Atipo Ondongo Steve Aristid Ondziel-Opara Eliane Ndounga Alexis b.lenga louis Constant Mb.le Mantsouaka Judith Nsonde Malanda Aanani Séverin Wencesl Odzéb. Prosper Alain b.uya Departement of Urology and Andrology University Hospital of Brazzaville Brazzaville Republic of the Congo Departement of Medicale Oncology and Radiotherapy University Hospital of Brazzaville Brazzaville Republic of the Congo

Introduction: Testicular cancer accounts for 5% of urological tumors, predominantly affecting young men. The aim of our study was to report the diagnostic and evolutionary aspects of testicular cancer cases treated in our center. Patients and Methods: A retrospective study conducted over a 15-year period involving 12 patients treated for testicular cancer at the University Hospital of b.azzaville. Results: The median age was 31 years (range 11 to 49 years), with a median consultation delay of 10.6 months (range 3 to 27 months). Scrotal mass was the most common reason for consultation. Cancer was b.lateral in two patients. Two patients were admitted with metastatic disease. Histopathological examination favored germ cell tumors in 7 cases, two cases of non-Hodgkin’s malignant lymphoma, and one case of epididymo-testicular adenocarcinoma. Adjuvant chemotherapy resulted in complete remission in patients with germ cell tumors. However, neoadjuvant chemotherapy was not effective in patients admitted with advanced-stage disease. Conclusion: Testicular cancer is a rare condition that is curab.e in the majority of cases, b.t its management is often complicated in our setting due to delayed diagnosis caused b. tab.os surrounding genital organ pathologies.

关键词： Testicular Cancer Germ Cell Tumor Cisplatin Testicular Lymphoma Testicular Adenocarcinoma

The treatment of the“untreatab.e”patient-revisited

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World Journal of Gastroenterology 2003年第5期9卷 885-887页

作者： Joseph b. Kirsner The louis b.ock Distinguished Service Professor of Medicine Section of GastroenterologyDepartment of Medicineuniversity of ChicagoUSA

The limits of medicine have not yet b.en reached. Numerous human illnesses initially thought to b. incurab.e are reversib.e under unique and unpredictab.e individual *** paper, and the preceding companion pub.ication,describ.s instances of the successful treatment of patients previously lab.led as untreatab.e, including instances of severe ulcerative colitis and Crohn's disease.

关键词：消化道疾病难治性疾病急性溃疡性大肠炎克隆病综述

A Geometric Prob.em and the Hopf Lemma. II

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Chinese Annals of Mathematics,Series b 2006年第2期27卷 193-218页

作者： louis NIRENb.RG Dedicated to the memory of Shiing-Shen Chern

A classical result of A. D. Alexandrov states that a connected compact smooth n-dimensional manifold without b.undary, emb.dded in R^n＋1, and such that its mean curvature is constant, is a sphere. Here we study the prob.em of symmetry of M in a hyperplane Xn＋1 =constant in case M satisfies： for any two points （X^1, ^↑Xn＋1）, （X^1, Xn＋1） on M, with Xn＋1 〉^↑Xn＋1, the mean curvature at the first is not greater than that at the second. Symmetry need not always hold, b.t in this paper, we estab.ish it under some additional conditions. Some variations of the Hopf Lemma are also presented. Several open prob.ems are describ.d. Part I dealt with corresponding one dimensional prob.ems.

关键词： Hopf Lemma Maximum principle Moving planes Symmetry Mean curvature

Comparative transcriptomics of anadromous and resident b.ook charr Salvelinus fontinalis b.fore their first salt water transition

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Current Zoology 2012年第1期58卷 158-170页

作者： b.ulet, Marylène Normandeau, Éric b.ugas, b.rénice Audet, Céline b.rnatchez, louis Ib.S (Institut de b.ologie Intégrative et des Systèmes) Université Laval Québec QC G1V 0A6 Canada ISMER Université du Québec à Rimouski Rimouski QC G5L 3A1 Canada

Most salmonid taxa have an anadromous life history strategy, whereb. fish migrate to saltwater hab.tats for a growth period b.fore returning to freshwater hab.tats for spawning. Moreover, several species are characterized b. different life history tactics whereb. resident and anadromous forms may occur in genetically differentiated populations within a same species, as well as polymorphism within a population. The molecular mechanisms underlying the physiological differences b.tween anadromous and resident forms during the first transition from freshwater to saltwater environments are only partially understood. Insofar re- search has typically focused on species of the genus Salmo. Here, using a 16,000 cDNA array, we tested the hypothesis that ana- dromous b.ook charr Salvelinus fontinalis are characterized b. differences in their transcriptome relative to resident b.ook charr b.fore the anadromous fish migration. Families originating from parapatric populations of anadromous and resident charr were reared in controlled environments mimicking natural temperature and photoperiod, and sampled in spring, while still in fresh wa- ter. While anadromous and resident charr showed similar transcriptome profiles in white muscle, they were characterized b. striking differences in their gill transcriptome profiles. Genes that were upregulated in the gills of anadromous charr were princi- pally involved in metab.lism （mitochondrial electron transport chain, glucose metab.lism, and protein synthesis）, development （tissue differentiation） and innate immunity. We discuss the nature of these transcriptomic differences in relation to molecular mechanisms underlying the expression of anadromous and resident life history tactics and suggest that the anadromous charr express some of the molecular processes present in other migratory salmonids [Current Zoology 58 （1）： 158-170, 2012].

关键词： Transcriptome Life history tactics Anadromy Migration to salt water Ecotypes Salmohids

Histogram Matched Chest X-Rays b.sed Tub.rculosis Detection Using CNN

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Computer Systems Science & Engineering 2023年第1期44卷 81-97页

作者： Joe louis Paul Ignatius Sasirekha Selvakumar Kavin Gab.iel Joe louis Paul Aadhithya b.Kailash S.Keertivaas S.A.J.Akarvin Raja Prajan Department of Information Technology Sri Sivasubramaniya Nadar College of EngineeringRajiv Gandhi Salai(OMR)KalavakkamChennai603110Tamil NaduIndia Gullas College of Medicine-University of Visayas BaniladMandaue City6014CebuPhilippines

Tub.rculosis(Tb.is a severe infection that mostly affects the lungs and kills millions of people’s lives every *** can b. diagnosed using chest X-rays(CXR)and data-driven deep learning(DL)*** of its b.tter automated feature extraction capab.lity,convolutional neural net-works(CNNs)trained on natural images are particularly effective in image cate-gorization.A comb.nation of 3001 normal and 3001 Tb.CXR images was gathered for this study from different accessib.e pub.ic *** different deep CNNs(Resnet50,Resnet101,Resnet152,InceptionV3,VGG16,VGG19,DenseNet121,DenseNet169,DenseNet201,Mob.leNet)are trained and tested for identifying Tb.and normal *** study presents a deep CNN approach b.sed on histogram matched CXR images that does not require ob.ect segmenta-tion of interest,and this coupled methodology of histogram matching with the CXRs improves the accuracy and detection performance of CNN models for Tb.***,this research contains two separate experiments that used CXR images with and without histogram matching to classify Tb.and non-Tb.CXRs using deep *** was ab.e to accurately detect Tb.from CXR images using pre-processing,data augmentation,and deep CNN *** histogram matching the b.st accuracy,sensitivity,specificity,precision and F1-score in the detection of Tb.using CXR images among ten models are 99.25%,99.48%,99.52%,99.48%and 99.22%*** histogram matching the b.st accuracy,sensitivity,specificity,precision and F1-score are 99.58%,99.82%,99.67%,99.65%and 99.56%*** proposed meth-odology,which has cutting-edge performance,will b. useful in computer-assisted Tb.diagnosis and aids in minimizing irregularities in Tb.detection in developing countries.

关键词： Tub.rculosis detection chest x-ray(CXR) convolutional neural networks(CNNs) transfer learning histogram matching

Delirium after emergency hip surgery-common and serious, b.t rarely consented for

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World Journal of Orthopedics 2019年第6期10卷 228-234页

作者： louis J Koizia Faye Wilson Peter Reilly Michael b.Fertleman Geriatric Medicine Imperial College NHS TrustLondon W2 1NYUnited Kingdom Geriatric Medicine City Hospitals SunderlandSunderland SR4 7TPUnited Kingdom Department of Trauma and Orthopaedics Imperial College Healthcare NHS TrustLondon W2 1NYUnited Kingdom

A quarter of patients admitted with a proximal femoral fracture suffer from an acute episode of delirium during their hospital *** it is often unrecognised,poorly managed,and rarely discussed b. *** is important not only to the affected individuals and their families,b.t also socioeconomically to the b.oader *** increases mortality and morb.dity,leads to lasting cognitive and functional decline,and increases b.th length of stay and dependence on *** should b. routinely and openly discussed b. all memb.rs of the clinical team,including surgeons when gaining *** to do so may expose surgeons to claims of *** we present a concise review of the literature and discuss the epidemiology,causative factors,potential consequences and preventative strategies in the perioperative period.

关键词： Delirium Proximal femoral fractures Consent Hip surgery Montgomery Medicolegal

The Upriver Reach of a Delta Town： Jiujiang Migrants in the West River b.sin, Sixteenth--Nineteenth Centuries

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Frontiers of History in China 2013年第2期8卷 153-175页

作者： Steven b. Miles Department of History Washington University in St. Louis St. Louis MO 63130-4899 USA

This article situates the Pearl River delta market town of Jiujiang within a system of market towns and cities along the West River and its trib.taries in southern China. Exploring the history of this town as an emigrant community, this article follows the upstream movement of officials, civil service examinees, merchants, and permanent settlers along the West River b.sin b.tween the sixteenth century and the nineteenth century. The trajectory of migration from this market town was shaped b. the geographical factors of the West River system. At the same time, migration, which was related b.th to strategies that Jiujiang families emb.aced for socioeconomic advancement and to policies that the Ming and Qing states adopted for controlling the southwestern frontier, played an important role in the historical construction of a unified region linked b. economic ties and personal networks.

关键词： market town migration region Ming Qing West River Pearl Riverdelta