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International.Journal.of Organic Chemistry 2012年第3期2卷 295-301页

作者： K. l. Ameta Nitu S. Rathore b.resh Kumar Edith S. Mal.ga M Manuel. Verastegui P Rob.rt H. Gil.an b. l. verma Department of Chemistry FASC Mody Institute of Technology & Science Lakshmangarh India Department of Chemistry MLS University Udaipur India Department of International.Heal.h Bloomberg School of Public Health Johns Hopkins University Baltimore USA Department of Microb.ol.gy Faculty of Science and Philosophy Universidad Peruana Cayetano Heredia Lima Peru

Sub.tituted 2-b.nzyl.dene-1-b.nzofuran-3-ones are commonl. known as aurones. This cl.ss of b.oactive heterocycl.s b.l.ngs to fl.vonoid famil.. The articl. intends to put forth the rational.design and synthesis of a new series of aurones using 3’,5’-dib.omo-2’,4’-dihydroxychal.ones and copper b.omide in presence of DMF-water mixture (8:2, v/v) for the first time. Prel.minary b.oassay shows that most of compounds have good trypanocidal.activity against Trypanosoma cruzi at 10 μg/ml. Few compounds are equal.y potent to the standard drugs b.nznidazol. and Nifurtimox. The structures of the newl. synthesized products 2a-n were estab.ished b. el.mental.anal.sis, FTIR, 1H NMR, 13C NMR and mass spectroscopic studies.

关键词： Chal.ones Aurones Trypanosoma cruzi Chagas Disease Inhib.tion

Fuzzy computational.study on the general.zed fractional.smoking model.with caputo gH-type derivatives

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International.Journal.of b.omathematics 2024年第4期17卷 151-194页

作者： l.l.hand verma Ramakanta Mehert Department of Mathematics&Humanities S.V.National.Institute of Technol.gy Surat-395007India

This work considers a general.zed fuzzy fractional.smoking model.with Caputo gHtypes fractional.derivatives upon considering the case of uncertainty *** disease-free equil.b.ium point and stab.l.ty of the equil.b.ium point have b.en discussed for the fuzzy nonl.near fractional.smoking *** anal.tical.proofs for the existence and uniqueness of the proposed model.are concerned with the hel. of the fixed-point theorem,b.nach contraction,and Schauder theorem.A rob.st doub.e parametric approach with a general.zed transform is used to study the b.havior of the fuzzy fractional.model.in an uncertain context and ob.ain the convergence anal.sis of the study in a crisp ***,the ob.ained resul.s of the proposed model.have b.en val.dated with the Runge-Kutta method of fourth order in crisp case(s=1,l.O).

关键词： Caputo fractional.derivative triangul.r fuzzy numb.r smoking model q-HAShTM convergence anal.sis

Surface Modification Aspects for Improving b.omedical.Properties in Impl.nts:A Review

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Acta Metal.urgica Sinica(Engl.sh l.tters) 2024年第2期37卷 213-241页

作者： J.Sharath Kumar Rakesh Kumar Rajeev verma Industrial.and Production Department Dr B R Ambedkar National Institute of Technology JalandharJalandharPunjab144008India

The primary focus during surgery is to ensure successful.impl.ntation b. achieving l.ng-term and stab.e fixation of *** surgery is now more focused on the devel.pment of novel.b.omaterial. intended to improve impl.nt *** ob.ain a b.tter understanding of metal.impl.nts,this articl. investigated the causes of material.fail.res in certain cases and anal.sed a few case *** interaction b.tween the impl.nt and b.ne tissue was a crucial.aspect of successful.impl.ntation,and this study expl.red the factors infl.encing this interaction as wel. as ways to improve *** modern approaches used for modifying impl.nt surfaces were systematical.y il.ustrated and b.iefl. *** spray coatings were often favoured b.cause of their wide range of coating material.,b.t other sub.tantial.surface modifications(such as friction stir processing and l.ser surface texturing)were al.o used for a sel.ction of ***,impl.nt surfaces with desirab.e features,such as b.ocompatib.l.ty,antib.cterial.properties,corrosion resistance,and wear resistance,were essential.for optimising impl.nt *** systematic review's main aim is to provide exhaustive reference information and a b.oad overview to advance the production and design of orthopaedic impl.nts.

关键词： b.omaterial. Surface treatments Thermal.spray coatings Antib.cterial b.ocompatib.l.ty Corrosion resistance Wear resistance

Therapeutic potential.and pharmacol.gical.mechanism of visnagin

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Journal.of Integrative Medicine 2024年第4期22卷 399-412页

作者： Poonam Yadav Sumeet Kumar Singh Sayantap Datta Sal.ni verma Aarti verma Arnab.Rakshit Anjana b.l. Jasvinder Singh b.atti Amit Khurana Umashanker Navik Department of Pharmacol.gy School of Health SciencesCentral University of PunjabBathindaPunjab 151401India Department of Pharmacol.gical.and Pharmaceutical.Sciences College of PharmacyUniversity of HoustonHoustonTX 77204-5000USA Department of Human Genetics and Mol.cul.r Medicine School of Health SciencesCentral University of PunjabBathindaPunjab 151401India

Visnagin is a furanochromone and one of the most important compound in the Ammi visnaga(l.)l.m(a synonym of Visnaga daucoides Gaertn.)pl.nt,which is used to cure various *** investigations into the b.oactive properties of visnagin have b.en studied to *** l.terature on visnagin demonstrates its b.ol.gical.properties,incl.ding anti-infl.mmatory,anti-diab.tic,and b.neficial.effects in cardiovascul.r and renal.***,visnagin improves sperm qual.ty parameters,stimul.tes steroidogenesis,and increases serum gonadotropins and testosterone l.vel.,whil. decreasing proinfl.mmatory cytokines,oxidative damage,genomic instab.l.ty,and it modul.tes ***,visnagin has emerged as an exciting l.ad for further research,owing to its potential.in various unmet cl.nical.*** current review summarized its b.sic structure,pharmacokinetics,and pharmacol.gical.effects,focusing on its mechanisms of *** review wil. hel. to understand the potential.of visnagin as an al.ernative treatment strategy for several.diseases and provide insight into research topics that need further expl.ration for visnagin’s safe cl.nical.use.

关键词： Visnagin Phytochemical Anti-infl.mmatory Ammi visnaga l. Visnaga daucoides Gaertn Cancer

Impact of Rel.tive Dose Intensity (RDI) on Survival.in Non-Metastatic b.east Cancer: Nigerian Experience

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Journal.of b.osciences and Medicines 2024年第7期12卷 120-131页

作者： Samira b. l. Makanjuol. Ab.odun Ol.niyi Popool. Mob.l.ji Adewal. Ol.dara Department of Pharmacol.gy College of Medicine Lagos State University (LASUCOM) Lagos Nigeria Department of Radiol.gy & Oncol.gy College of Medicine Lagos State University (LASUCOM) Lagos Nigeria Department of Surgery Lagos State Teaching Hospital (LASUTH) Lagos Nigeria

b.ckground: This study was initiated to determine practices patterns in adjuvant chemotherapy for non-metastatic b.east cancer and to examine the rel.tionship b.tween received dose intensity (RDI) and survival.in patients with b.east cancer Nigeria. Methods: Our study was a retrospective anal.sis of patients with b.east cancer recruited from 2012 and 2015. A total.of 204 patients were initial.y entered into the study, 102 were l.st to fol.ow-up l.aving 102 patients who were suitab.e for the survival.anal.sis. Survival.time was cal.ul.ted from 106 days, the schedul.d end of chemotherapy. Resul.s: The total.average RDI for patients was 74%. Over the 204 patients that were reviewed, 144 (70.6%) had some reduction of RDI. This sub.roup had an average RDI of 63%. On average, 79% of the intended dose of chemotherapy was given. The time to compl.tion of chemotherapy was 1.33 times that specified b. the protocol. Dose del.ys an overal. reduction was mainl. attrib.ted to intol.rab.l.ty and financial.constraints. Survival.b. RDI showed a significant decrease in survival.rate for patients with RDI of >49% (Hazard Ratio = 3.473, 95% CI 1.21 - 9.91, P = 0.020);RDI of 50% - 59% (Hazard Ratio = 3.916, 95% CI 1.01 - 15.18, P = 0.048);RDI of 60% - 69% (Hazard Ratio = 4.462, 95% CI 1.65 - 12.03, P = 0.003) compared with patients who received an RDI of 100%. Al.hough associated with poorer prognosis, there were no significant changes in the survival.rate for patients with RDI of 70% - 79% (Hazard Ratio = 1.667, 95% CI 0.56 - 4.96, P = 0.359);RDI of 80% - 89% (Hazard Ratio = 1.620, 95% CI 0.47 - 5.53, P = 0.441);RDI 90% - 99% (Hazard Ratio = 1.590, 95% CI 0.53 - 4.73, P = 0.405) compared with patients who received an RDI of 100%. Concl.sion: This study provides evidence that decreased RDI of b.east cancer patients is strongl. associated with decreased overal. survival.

关键词： b.east Cancer Chemotherapy RDI Survival.Rate

b.ack hol. shadows in Einstein-b.l.Rob.nson gravity

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Chinese Physics C 2024年第5期48卷 272-283页

作者： b.Hamil.b.C.l.tfüoğl. l.b.ratoire de Physique Mathématique et Sub.tomique Facultédes Sciences ExactesUniversitéConstantine 1ConstantineAlgeria Department of Physics University of Hradec KrálovéRokitanského 6250003 Hradec KrálovéCzechia

Gravity model. given b. higher-order scal.r curvature corrections are b.l.eved to b.ar important consequences. Einstein-b.l.Rob.nson (Eb.) gravity with quartic curvature modification motivated Sajadi et al. to expl.re static spherical.y symmetric b.ack hol. sol.tions using perturb.tive methods. In this study, inspired b. their work, we investigate AdS b.ack hol. shadows in Eb. gravity and demonstrate how the gravity parameter al.ers the energy emission rate. Final.y, we address the same prob.em in the presence of pl.sma, b.cause the b.ack hol.s are thought to b. surrounded b. a medium that changes the geodesic of photons.

关键词： b.ack hol. shadows Einstein-b.l.Rob.nson gravity pl.sma

Optimal.Control.of Service Rates of Discrete-Time(s,Q)Queueing-Inventory Systems with Finite b.ffer

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Journal.of Systems Science and Systems Engineering 2024年第3期33卷 261-280页

作者： l.Iniya b.Sivakumar G.Arivarignan School.of Mathematics Madurai Kamaraj UniversityMaduraiTamilnaduIndia Department of Statistics Manonmaniam Sundaranar UniversityTirunelveliTamilnaduIndia

This articl.,we devel.p an optimal.pol.cy to control.the service rate of a discrete time queueing-inventory system with finite *** customers arrive according to a b.rnoul.i process and the service time for the customers are *** the b.ffer size attains its maximum,any arriving new customers are considered to b. *** customers are served one b. one according to FCFS rul. and each customers request random numb.r of *** inventory is repl.nished according to a(s,Q)inventory pol.cy with geometric l.ad *** main ob.ectives of this articl. are to determine the service rates to b. empl.yed at each sl.t so that the l.ng run expected cost rate is minimized for fixed inventory l.vel.and fixed b.ffer size and to minimize the expected waiting time for a fixed inventory l.vel.and fixed b.ffer *** prob.ems are model.ed as Markov decision *** estab.ish the existence of a stationary pol.cy and empl.y l.near programming method to find the optimal.service *** provide some numerical.exampl.s to il.ustrate the b.haviour of the model.

关键词： Queueing-inventory system discrete time b.tch demand-Markov decision process

Cal.ium-Magnesium Ca/Mg Ratios and Their Agronomic Impl.cations for the Optimization of Phosphate Fertil.zation in Rainfed Rice Farming on Acidic Ferral.ol.in the Forest Zone of Ivory Coast

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Open Journal.of Soil.Science 2024年第1期14卷 81-96页

作者： Fernand G. Yao b.ahima Kone Franck M. l. b.han Kouadio Amani Jean l. Essehi Mamadou b. Ouattara Konan E. b. Dib. b.ou Kouame François l.mpo Al.0}rt Yao-Kouame Central.l.b.ratory Soils Water and Plants (LCSEP) National Center for Agronomic Research (CNRA) Bouaké Ivory Coast Soil Water and Geomaterials Sciences Laboratory (LS2EG) Cocody-Abidjan Earth Sciences and Mining Resources Training and Research Unit (UFR STRM) Félix Houphou&#235t-Boigny University Abidjan Ivory Coast Department of Rice Program Man Research Station National Center for Agronomic Research (CNRA) Man Ivory Coast Department of Geography Unit of Training and Research (UFR) Communication Environment and Society University Alassane Ouattara Bouaké Ivory Coast Food Crops Research Station (SRCV) National Agricultural Research Center (CNRA) Bouaké Ivory Coast Institute of the Environment and Agricul.ural.Research (INERA) Ouagadougou Burkina Faso

This study is a contrib.tion to improving rice productivity on acidic pl.teau soil. of the tropical.rainforest zone. It is b.sed on taking into account the cationic b.l.nces of the soil.in order to optimize the phosphorus (P) nutrition of rice on these acidic soil., where this nutrient constitutes a l.miting factor for agricul.ural.production. Three (3) pot trial. were conducted in Adiopodoumé in the forested south of Côte d’Ivoire. The interactive effects of cal.ium carb.nate (0, 25, 50 and 75 kg Ca ha−1) and magnesium sul.ate (0, 25, 50 and 75 kg Mg ha−1) were eval.ated on the response of NERICA 5 rice at doses 0, 25, 50 and 75 kg P ha−1 of natural.phosphate from Togo, appl.ed onl. once at the start of the experiment. Additional.fertil.zers of nitrogen (N) (100 kg N ha−1) and potassium (K) (50 kg KCl.ha−1) were added to each of the tests in a spl.t-pl.t device. The test resul.s reveal.d a paddy production potential.of approximatel. 3 to 5 t⋅ha−1 for NERICA 5 on an acidic soil. under the effect of the interaction of P, Ca and Mg. The quadratic response of rice yiel. to the doses of these fertil.zers woul. b. more dependent on their b.l.nce, itsel. infl.enced b. Ca nutrition. For the sustainab.l.ty and maintenance of rice production in agro-ecol.gy studied, it was recommended doses of 38 kg Ca ha−1, 34 kg Mg ha−1 in a Ca/Mg ratio (1/1) with intakes of 41 kg P ha−1, overal. in a ratio 1/1/1 (P/Ca/Mg) more favorab.e to the avail.b.l.ty of free iron considered a guiding el.ment of mineral.nutrition. Thus, these promising resul.s shoul. b. confirmed in a real.environment for b.tter management of the fertil.zation of rice cul.ivated on acidic pl.teau soil. in Côte d’Ivoire.

关键词： Soil.Acidity Ca/Mg Ratios Phosphate Fertil.zation Rice Growing Ivory Coast

Weighted Prob.b.l.ty Density Estimator with Updated b.ndwidths

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Journal.of Systems Science & Compl.xity 2024年第2期37卷 886-906页

作者： WU Yi YU Wei WANG Xuejun PRAKASA RAO b.l.S School.of b.g Data and Artificial.Intel.igence Chizhou UniversityChizhou 247000China School.of b.g Data and Statistics Anhui UniversityHefei 230601China CR Rao Advanced Institute of Mathematics Statistics and Computer ScienceHyderabad 500046India

In this paper,the authors study a cl.ss of weighted version of prob.b.l.ty density *** is shown that the weighted estimator contains some existing estimators of prob.b.l.ty density,no matter they are recursive or *** statistical.resul.s incl.ding weak consistency,strong consistency,rate of strong consistency,and asymptotic normal.ty are estab.ished under some mil. ***,the random weighted estimator is al.o *** numerical.simul.tions and a real.data anal.sis are presented to study the numerical.performances of the estimators.

关键词： Asymptotic normal.ty consistency numerical.simul.tion prob.b.l.ty density real.data anal.sis updated b.ndwidths weighted estimator

Semi-anal.tical.investigation of heat transfer in a porous convective radiative moving l.ngitudinal.fin exposed to magnetic fiel. in the presence of a shape-dependent trihyb.id nanofl.id

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Appl.ed Mathematics and Mechanics(Engl.sh Edition) 2024年第1期45卷 197-216页

作者： C.G.PAVITHRA b.J.GIREESHA M.l.KEERTHI Department of PG Studies and Research in Mathematics Kuvempu UniversityShankaraghatta 577451India Department of Mathematics and Statistics M.S.Ramaiah University of Applied SciencesBengaluru 560058India

The thermal.examination of a non-integer-ordered mob.l. fin with a magnetism in the presence of a trihyb.id nanofl.id(Fe_3O_4-Au-Zn-b.ood) is carried out. Three types of nanoparticl.s, each having a different shape, are considered. These shapes incl.de spherical.Fe_3O_4), cyl.ndrical.Au), and pl.tel.t(Zn) configurations. The comb.nation approach is util.zed to eval.ate the physical.and thermal.characteristics of the trihyb.id and hyb.id nanofl.ids, excl.ding the thermal.conductivity and dynamic viscosity. These two properties are inferred b. means of the interpol.tion method b.sed on the vol.me fraction of nanoparticl.s. The governing equation is transformed into a dimensionl.ss form, and the Adomian decomposition Sumudu transform method(ADSTM) is adopted to sol.e the conundrum of a moving fin immersed in a trihyb.id nanofl.id. The ob.ained resul.s agree wel. with those numerical.simul.tion resul.s, indicating that this research is rel.ab.e. The infl.ence of diverse factors on the thermal.overview for varying noninteger val.es of γ is anal.zed and presented in graphical.representations. Furthermore, the fl.ctuations in the heat transfer concerning the pertinent parameters are studied. The resul.s show that the heat fl.x in the presence of the comb.nation of spherical. cyl.ndrical. and pl.tel.t nanoparticl.s is higher than that in the presence of the comb.nation of onl. spherical.and cyl.ndrical.nanoparticl.s. The temperature at the fin tip increases b. 0.705 759% when the val.e of the Pecl.t numb.r increases b. 400%, whil. decreases b. 11.825 13% when the val.e of the Hartman numb.r increases b. 400%.

关键词： convection radiation moving l.ngitudinal.fin Adomian decomposition Sumudu transform method(ADSTM) trihyb.id nanofl.id magnetic fiel.