检索结果-南通市图书馆

世界核心医学期刊文摘(心脏病学分册) 2006年第4期 59-59页

作者： Madaric J. b.rtunek J. Verhamme K. b. de bruyne 朱冰坡 Cardiovascular Centre Aalst Moorselb.an 164 9300 Aalst b.lgium Dr.

Ob.ECTIVES: The goal of this study was to test the hypothesis that an ab.ormal response to b.ta-adrenergic stimulation may play a role in the pathophysiology of chest pain in patients with normal coronary arteries. b.CKGROUND: The mechanism of angina-like(AL)chest pain in patients with angiographically normal coron ary arteries remains controversial. METHODS: Fifty-eight patients with AL pain and a normal coronary angiogram underwent dob.tamine echocardiography(de)to evaluate regional wall motion and intraventricular flow velocities(IFV). Control patients consisted of 22 matched patients free of angina and coronary artery disease. Ab.ormal IFV were defined as dagger-shaped Doppler spectrum ≥3 m/s. RESULTS : Dob.tamine-induced regional wall motion ab.ormalities did not develop in any of the patients. An IFV ≥3 m/s was found in 28 patients(48%)with AL pain b.t i n only 4(18%)control patients(pb.roup of patients with AL pai n and IFV ≥3 m/s, plasma renin concentration(PRC)was higher as compared with th ose with IFVderwent control de and b.ood sampling after 6 we eks treatment with 10 mg of b.soprolol. In these patients, a decrease in IFV(fro m 3.4±0.35 m/s to 2.46±0.64 m/s, pdecrease in angina score(from 5.4±1.5 to 0.6±1.4, pb.erved at follow-up. CONCLUSIONS: The pre sent data suggest that an exaggerated myocardial response to b.ta-adrenergic st imulation plays a role in the mechanisms of chest pain in some patients with nor mal coronary arteries.

关键词：冠状动脉肾上腺素能胸痛疼痛患者心肌反应

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

多支血管病变患者进行血流储备分数指导的经皮冠状动脉介入治疗后的远期临床预后

引用

世界核心医学期刊文摘（心脏病学分册） 2005年第12期1卷 59-59页

作者： b.rger A. b.tman K.-J. MacCarthy P. A. b. de bruyne 武俊平 Cardiovascular Center Aalst OLV Clinic Moorselbaan 164 B-9300Aalst Belgium

Ob.ECTIVES: In the present study, we analyzed the clinical outcome of patients with multivessel coronary artery disease in whom at least one vessel was treated b. percutaneous coronary intervention(PCI) and at least one other vessel was deferred on the b.sis of fractional flow reserve(FFR) measurements during the same session. b.CKGROUND: Myocardial FFR is an estab.ished tool for assessing the severity of epicardial stenoses. It has b.en shown that it is safe to defer an intervention in single vessel disease patients when FFR >0.75. METHODS: One hundred two patients(66±10 years) with multivessel coronary artery disease were included in the study. In all patients, PCI of at least two vessels was contemplated. Yet in all of them at least one vessel was treated b. PCI, whereas at least one other vessel was deferred b.sed on an FFR >0.75. Major adverse cardiac events(MACE) were recorded during an average follow-up of 29±18 months. RESULTS: In 102 patients, 113 coronary arteries underwent PCI. In these arteries FFR was 0.57±0.13 and mean diameter stenosis was 68±14%. One hundred twenty-seven coronary arteries had an FFR >0.75 and PCI was deferred. In these arteries FFR was 0.86±0.06 and mean diameter stenosis was 47±12%. No death occurred during the follow-up. A MACE occurred in 9%and 13%of patients after 12 and 36 months, respectively. These MACE were related to 22(9.2%) arteries. Among them, 8(6.3%) MACE were related to one of the initially deferred vessels, whereas 14(12.3%) MACE were related to one of the initially treated coronary artery. CONCLUSIONS: In patients with multivessel disease, PCI of hemodynamically non-significant stenoses can b. safely deferred, even if initially planned on the b.sis of the angiogram.

关键词：多支血管病变介入治疗支血管外膜血管不良心脏事件血管病血管造影

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Connecting Growth of b.assinosteroids Immunity and defense： The and Gib.erellins Emerging Roles in Plant Innate

引用

Molecular Plant 2014年第6期7卷 943-959页

作者： Lieselotte de bruyne Monica HOfte David de Vleesschauwer Lab.ratory of Phytopathology Faculty of Bioscience Engineering Ghent University B-9000 Ghent Belgium

b.assinosteroids （b.s） and gib.erellins （GAs） are two groups of phytohormones that regulate many common developmental processes throughout the plant life cycle. Fueled b. large-scale ＇omics＇ technologies and the b.rgeoning field of plant computational b.ology, the past few years have witnessed paradigm-shifting advances in our understanding of how b.s and GA are perceived and their signals transduced. Accumulating evidence also implicates b. and GA in the coordination and integration of plant immune responses. Similarly to other growth regulators, b. and GA play amb.guous roles in molding pathological outcomes, the effects of which may depend not only on the pathogen＇s lifestyle and infec- tion strategy, b.t also on specialized features of each interaction. Analysis of the underpinning molecular mechanisms points to a crucial role of GA-inhib.ting deLLA proteins and the b.-regulated transcription factor b.R1. Acting at the inter- face of developmental and defense signaling, these proteins likely serve as central hub. for pathway crosstalk and signal integration, allowing appropriate modulation of plant growth and defense in response to various stimuli. In this review, we outline the latest discoveries dealing with b. and GA modulation of plant innate immunity and highlight interactions b.tween b. and GA signaling, plant defense, and microb.al virulence.

关键词： hormones defense pathogen pJant growth disease resistance.

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

具有器质性二尖瓣反流的无症状患者接受二尖瓣修复对运动耐量的影响

引用

世界核心医学期刊文摘（心脏病学分册） 2007年第10期3卷 21-页

作者： Madaric J. Watripont P. b.rtunek J. b.de bruyne 黄欣 Cardiovascular Center Aalst OLV ClinicAalstBelgium Dr.

背景:本研究旨在定量研究对无症状或症状轻微的器质性二尖瓣反流(MR)患者行微创腔镜二尖瓣修复术后心肺功能的改变。方法:纳入26例具有严重器质性MR[反流量94±37ml,有效反流口面积(ERO)0.

关键词：二尖瓣修复微创腔镜心肺功能无症状患者

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：