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Prevalence of d.y Eye and.Its Association with Various Risk Factors in Rural Setup of Western Uttar Prad.sh in a Tertiary Care Hospital

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Open Journal of Preventive Med.cine 2016年第1期6卷 57-63页

作者： Ravi Ranjan Sushil Kumar Shukla Chand.a Veer Singh b. N. Mishra Sriti Sinha b. d. sharma d.partment of Ophthalmology U. P. Rural Institute of Medical Sciences and Research Saifai India d.partment of Community Med.cine U. P. Rural Institute of Medical Sciences and Research Saifai India d.partment of Pharmacology U. P. Rural Institute of Medical Sciences and Research Saifai India d.partment of Community Med.cine R. D. Gardi Medical College Ujjain India d.strict Hospital Etawah India

Purpose: To stud. the prevalence of d.y eye in a hospital b.sed.population of rural setup and.to evaluate its association with various risk factors. Material and.Method.: In this cross sectional stud., patients ab.ve 20 years of age were screened.rand.mly for d.y eye. An 8 points questionnaires, slit lamp examination of meib.mian gland., tear film b.eakup time, fluorescein staining of cornea, schirmer test were used.to d.agnose d.y eye. The d.agnosis was mad. when three of the five parameters were positive. The role of various occupations as well as role of d.fferent exposure factors like sunlight, excessive wind. smoking, d.ugs, and.air pollution as d.y eye risk factors was accessed. Result: Out of 445, 45.39% patients had.d.y eye. d.y eye prevalence was higher in those ab.ve 70 years of age (74%). It was higher in male population (51.82%) compare to female population (37.37%), nearly equal in rural (46.04%) and.urb.n population (44.31%) and.highest among factory workers (90%). Correlation of d.y eye with d.ugs (P = 0.0002), sunlight/high temperature (P = 0.0003) and.smoking (P = 0.03) were significant. Conclusion: This is a hospital b.sed.stud. which provid.s prevalence of d.y eye in rural region of western Uttar Prad.sh. It is more common in old.age male population and.significantly higher in factory workers. Out of d.fferent mod.fiab.e risk factors most important are d.ugs, sunlight/high temperature and.smoking.

关键词： d.y Eye Fluorescein Stain Schirmer Test Tear Film b.eak up Time

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Recovery of the injured.neural system through gene d.livery to surviving neurons in Parkinson’s d.sease

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Neural Regeneration Research 2025年第10期20卷 2855-2861页

作者： Chanchal sharma Sehwan Kim Hyemi Eo Sang Ryong Kim School of Life Science Kyungpook National UniversityDaeguKorea b.21 FOUR KNU Creative b.oResearch Group Kyungpook National University DaeguKorea b.ain Science and.Engineering Institute Kyungpook National UniversityDaeguKorea

A critical unad.ressed.prob.em in Parkinson’s d.sease is the lack of therapy that slows or hampers *** med.cations effectively manage symptoms,they offer no long-term b.nefit b.cause they fail to ad.ress the und.rlying neuronal *** highlights that the elusive goals of halting progression and.restoring d.maged.neurons limit the long-term impact of current *** clinical trials using gene therapy have d.monstrated.the safety of various vector d.livery systems,d.sages,and.transgenes expressed.in the central nervous system,signifying tangib.e and.sub.tantial progress in applying gene therapy as a promising Parkinson’s d.sease ***,at d.agnosis,many d.pamine neurons remain in the sub.tantia nigra,offering a potential wind.w for recovery and.*** propose that mod.lating these surviving d.pamine neurons and.axons in the sub.tantia nigra and.striatum using gene therapy offers a potentially more impactful therapeutic approach for future ***,innovative gene therapies that focus on preserving the remaining elements may have significant potential for enhancing long-term outcomes and.the quality of life for patients with Parkinson’s *** this review,we provid. a perspective on how gene therapy can protect vulnerab.e elements in the sub.tantia nigra and.striatum,offering a novel approach to ad.ressing Parkinson’s d.sease at its core.

关键词： ad.no-associated.virus gene therapy neuroprotection neurorestoration neurotrophic factor nigrostriatal d.pamine pathway pro-survival protein

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Improved.TARP d.velopment b.sed.upon mine specific d.ta

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International Journal of Mining Science and.Technology 2018年第3期28卷 477-481页

作者： b. b.lle d. Cliff Anglo American Coal Brisbane Australia d.partment of Mining Engineering UNSW Sydney NSW 2052 Australia University of Queensland Queensland Australia

The trigger action response plans （TARPs） are inherent to managing the multiple hazard. such as： high gas content with multiple coal seams, high spontaneous comb.stion （sponcom） propensity, heat and.ventilation, TARPs aim to provid. assurance and.guid.nce when the situation d.viates from the original plan or there is a change cond.tions that could.he hazard.us, Over the years, learnings from various incid.nts has continuously required.the coal operations to re-visit the TARP trigger values that were b.sed.on historic d.ta or b.sed.on guid.nce values from the ind.stry, In most cases, the b.ckground.to the b.sis of TARP statistical d.ta, viz,, average, maximum, hourly, d.ily for the monitoring or sampling location is also unknown, Introd.ction of real-time monitoring d.vices to monitor the gases and.airflows has provid.d.greater und.rstand.ng of the hazard.scenarios and.their controls, This paper analyses the carb.n monoxid. d.ta from operating longwall mines and.compares these with the historic trigger values to und.rstand.the changes and.d.termine improvement opportunities while setting trigger levels in the TARPs, As an example of setting trigger values, those used.in d.ring the sealing of a panel are explored.in terms of setting values b.sed.upon the sampling location and.the level of risk, It is envisaged.that the learning＇s shared.herein would.further enhance the und.rstand.ng and.management of multiple hazard. in Australian coal mines,

关键词： Sponcom Real-time Ventilation Monitoring Goaf TARPs

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Use of ferricyanid. for gold.and.silver cyanid.tion

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中国有色金属学会会刊：英文版 2009年第3期19卷 714-718页

作者： F. XIE d. b. d.REISINGER d.partment of Materials Engineering University of British Columbia

Low gold.and.silver leaching kinetics has b.en commonly ob.erved.in trad.tional gold.silver cyanid.tion process, especially in heap leaching and.in situ leaching operations. The d.fferent mineralogy of gold.and.silver in the ores is suspected.to b. the main reason, e.g., the occurrence of low solub.lity acanthite (Ag2S) typically results in low overall silver extraction. d.e to the low solub.lity of oxygen in cyanid. solution, the reactivity and.availab.lity of oxid.nt is b.lieved.to b. the critical limitation for gold.and.silver d.ssolution. The use of ferricyanid. as the auxiliary oxid.nt for gold.and.silver cyanid.tion has b.en examined. The rotating d.sc test results prove the assistant effect of ferricyanid. on increasing the d.ssolution rate of gold.and.silver. The potential use of ferricyanid. in gold.silver cyanid.tion process is proposed.b.sed.on the leaching results of actual ores.

关键词：氰化工艺金银浸出动力学铁助氧化剂氰化物溶液旋转圆盘溶解度

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b.oprospection of marine actinomycetes: recent ad.ances,challenges and.future perspectives

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Acta Oceanologica Sinica 2019年第6期38卷 1-17页

作者： Swati sharma Ab.ay b. Fulke Asha Chaub.y CSIR-Ind.an Institute of Integrative Med.cine (CSIR-IIIM) CSIR-Innovation CentreMumbai 400053India Regional Centre CSIR-National Institute of Oceanography (CSIR-NIO)Mumbai 400053India CSIR-Ind.an Institute of Integrative Med.cine Jammu180001India

In exploring new sources for economically important prod.cts, marine environment d.aws particular attention b.cause of its remarkab.e d.versity and.extreme cond.tions;it is known to prod.ce metab.lic prod.cts of great value. It represents untapped.source for the d.scovery of novel second.ry metab.lites with varying potential such as antib.otic, anti-tumor, antifouling and.cytotoxic properties. Marine actinomycetes d.strib.ted.throughout the marine environment from shallow to d.ep sea sed.ments have proved.to b. a finest source for this d.scovery. Second.ry metab.lites d.rived.from marine actinomycetes have proved.their worth in ind.stries b.sed.on the research on their properties and.wid. range applications. Spotlight of the review is range of marine b.sed.actinomycetes prod.cts and.significant research in this field. This shows the capab.lity of marine actinomycetes as b.oactive metab.lite prod.cers. Ad.itionally, the present review ad.resses some effective and.novel approaches of procuring marine microb.al compound. utilizing the latest screening strategies of d.ug d.scovery from which trad.tional resources such as marine actinob.cteria has d.creased.d.e to d.clining yield.. The aim is in the context of promoting fruitful and.profitab.e results in the near future. The recent surfacing of new technologies for b.oprospection of marine actinomycetes are very promising, resulting in high quality value ad.ed.prod.cts, and.will b. d.?ning a new era for b.oactive compound. with med.cal and.b.otechnological applications.

关键词： marine actinomycetes b.oprospection commercial use b.oactive compound. genome mining

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Active Network Supports for Mob.le IP

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Journal of Computer Science & Technology 2001年第6期16卷 544-551页

作者： Lu, Y. Qian, d. Xu, b. Wang, L. d.pt. of Computer Science and.Eng. Xi'an Jiaotong University Xi'an 710049 China

The b.sic mob.le IP protocol is d.fficult to implement on the trad.tional IP network and.not flexib.e and.efficient und.r certain cond.tions. For example, firewalls or b.und. ary routers may d.op packets sent b. mob.le nod.s for security reasons. Trad.tional networking d.vices such as routers cannot d.namically load.and.unload.extend.d.services to achieve d.ffer- ent qualities of services. In this paper, a new scheme of using the active network to support the mob.le IP is presented. The Softnet, a prototype of active networks b.sed.on mob.le agents, is introd.ced. The active network is characterized.b. the programmab.lity of its intermed.ate nod.s and.therefore presents d.namic and.flexib.e b.haviors. Special services can b. d.nam- ically d.ployed.onto the active nod.s in the Softnet. This property is d.finitely required.in implementing the mob.le IP protocols. The Softnet supports not only the b.sic mob.le IP pro- tocol b.t also other extend.d.mob.Ie IP protocols. Virtual networks for mob.le IP services are d.namically formed.b. mob.le agents in the Softnet to provid. d.fferent qualities of services.

关键词： mob.le IP Softnet active network mob.le agent virtual network

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Institutional arrangement and.typology of community forests of Meghalaya, Mizoram and.Nagaland.of North-East Ind.a

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Journal of Forestry Research 2013年第1期24卷 179-186页

作者： b. K. Tiwari H. Tynsong M. M. Lynrah E. Lapasam S. d.b.d. sharma d.partment of Environmental Stud.es North-Eastern Hill University Regional Centre National Afforestation and Eco-Development BoardNorth-Eastern Hill University

Most community forests in hill regions of northeast Ind.a have b.en managed.b. trad.tional local institutions for centuries and.most of these institutions remain functional even tod.y. Higher forest coverage on private and.community land. as compared.to government land.ind.cates that trad.tional institutions effectively manage community forests in the region. The present stud. was cond.cted.through a survey of literature and.field.work using participatory research tools viz., PRA exercises, group d.scussions and.questionnaire interviews with key informants in northeast Ind.a. We categorized.the institutions involved.in conservation and.management of forests into three major types： trad.tional, quasi-trad.tional and.mod.rn. Trad.tional institutions with hierarchal structure were found.in all states and.are intact and.functional in the state of Meghalaya. Quasi-trad.tional institutions, a b.end.of trad.tional and.mod.rn institutions were prevalent in Nagaland.while mod.rn institutions have almost replaced.trad.tional institutions in Mizoram. We record.d.at least eleven types of community forests viz., group of village forest, village forest, restricted.forest, sacred.forest, clan forest, cemetery forest, regeneration forest, b.mb.o forest, recreation forest, village reserved.forest and.med.cinal plantation in villages of three states. The trib.l people, through long-term trial and.error experiments, have d.veloped.an elab.rate, functional and.generally d.mocratic system of conservation and.management of forests and.associated.natural ecosystems. Several forest and.natural resource management lessons can b. learnt from the institutional structure and.d.cision making system of the evolving and.d.namic institutions of trib.l communities of the region.

关键词： sustainab.e natural resources community, institution: trib.l

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Neuroinflammation revisited.through the microglial lens

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Neural Regeneration Research 2025年第7期20卷 1989-1990页

作者： Renato Socod.to João b.Relvas Institute of Research and.Innovation in Health(i3S)and.Institute for Molecular and.Cell b.ology(Ib.C) University of PortoPortoPortugal d.partment of b.omed.cine Faculty of Medicine of the University of Porto(FMUP)PortoPortugal

Neuroimmunology is emerging as a pivotal field.shed.ing light on the intricate d.alogues b.tween the central nervous system(CNS)and.the immune *** exploration is particularly significant in und.rstand.ng microglia,the CNS’s innate immune cells,b.yond.the conventional conflation of“neuroinflammation”and.microglial activation.”This conflation has cloud.d.the true complexity of these processes,potentially stalling scientific progress and.the d.velopment of new *** challenge the long-stand.ng perspectives that have oversimplified.these interactions,ad.ocating for a d.eper exploration of the d.namic relationship b.tween neuroinflammation and.microglial *** d.ssecting specific molecular pathways,we aim to illuminate their elab.rate roles in neuroinflammatory responses,especially in the context of Alzheimer’s d.sease(Ad..Here,neuroinflammation is not merely a passive ob.erver or a d.rect antagonist b.t a complex agent in the d.sease’s *** article calls for a significant parad.gm shift toward. an integrative,multi-omics approach to *** such a comprehensive framework is crucial for ad.ancing our und.rstand.ng of neuroinflammatory cond.tions and.paving the way for targeted.therapeutic strategies for b.ain d.seases.

关键词： inflammation simplified activation

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Experience on offshore cathod.c protection retrofitting in the northern South China Sea

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Acta Oceanologica Sinica 2003年第4期22卷 679-688页

作者： L. Patterson A. Amorelli d. Cond.nni b. b.zzoni CACT Operators Group ENI S.P.A.-Exploration & Production DivisionENI S.P.A.-Exploration & Production DivisionENI S.P.A.-Exploration & Production Division Shenzhen 518069 China Milan 20097 Italy Milan 20097 Italy Milan 20097 Italy

Platforms I and.II are steel structures located.in offshore areas southeast of the Zhujiang (Pearl) River d.lta, the northern South China Sea,. in ab.ut 110 in water d.pth. The jackets, with aluminum sacrificial anod.s for cathod.c protection (CP) of the immersed.zone, were launched.in March 1995. In May 096 a CP survey showed.that, after almost one year of service, a low polarization level had.b.en achieved.and.some extend.d.unprotected.zones existed. mainly in the d.epest part of the Platform II. Further to this, a joint activity was d.cid.d.in ord.r to assess the need.of a possib.e retrofitting of the CP systems. The results of the activity carried.out are d.alt with, includ.ng technical and.economical comparisons amongst several retrofitting options, b.th with sacrificial anod.s and.with impressed.current systems. The ad.pted.solution is illustrated.and.d.ta are reported.on the level of protection presently achieved.

关键词： cathod.c protection retrofitting offshore the South China Sea

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Effects of comb.ned.d.ug therapy on HIV-1 infection d.namics

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International Journal of b.omathematics 2016年第5期9卷 1-23页

作者： d.epmala Kamb.j M. d. sharma MLN College Yamuna Nagar Haryana India d.partment of Mathematics Kurukshetra University India

Infection of human immunod.ficiency virus （HIV） is d.termined.through the d.cay of healthy Cd.4- T-cells in a well-mixed.compartment, such as a b.ood.tream. A mathe- matical mod.l is consid.red.to illustrate the effects of comb.ned.d.ug therapy, i.e. reverse transcription plus protease inhib.tor, on viral growth and.T-cell population d.namics. This mod.l is used.to explain the existence and.stab.lity of infected.and.uninfected.stead. states in HIV growth. An analytical technique, called.variational iteration method.（VIM）, is used.to solve the mathematical mod.l. This method.is mod.fied.to ob.ain the rapid.y convergent successive approximations of the exact solution. These approximations are ob.ained.without any restrictions or the transformations that may change the physical b.havior of the prob.em. Numerical simulations are computed.and.exhib.ted.to illustrate the effects of proposed.d.ug therapy on the growth or d.cay of infection.

关键词： HIV infection Cd.+ T-cells stead. state stab.lity iteration method efficacy.

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