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Clinical and Therapeutic Aspects of Giant Fib.oids at the Hôpital du Mali ab.ut 30 Cases

Open Journal of Ob.tetrics and Gynecology 2020年第6期10卷 778-789页

作者： Mamadou b. Coulib.ly Alassane Traore Mody A. camara Ab.rahamane Togo Adama Sangaré Issa Ongoib. Kalb. Timb.ne Amadou Sidib. Apérou Guindo Niani Mounkoro Ib.ahim Teguete Youssouf Traore Moustaphe Toure Service of Gynecology of the Hopital du Mali Bamako Mali Service of Medical Imaging of the Hopital du Mali Bamako Mali Service of Anesthesia and Resuscitation of the Hopital du Mali Bamako Mali Service of Gynecology-Ob.tetrics of Gab.iel TOURE Teaching Hospital Bamako Mali

The fib.oids affect 20% to 25% of women of reproductive age and are 3 to 9 times more common in b.ack women. We’ll talk ab.ut giant fib.oids (GFs) when uterine height reaches or exceeds the navel. We have initiated ... 详细信息

The fib.oids affect 20% to 25% of women of reproductive age and are 3 to 9 times more common in black women. We’ll talk about giant fibroids (GFs) when uterine height reaches or exceeds the navel. We have initiated this study in order to report the epidemioclinical and therapeutic aspects of giant fibroids at the Hopital du Mali. A descriptive retro-prospective study, conducted in the service of gynecology of the Hopital du Mali from November 2017 to December 2018 were included in this study, any patients, regardless of their age, having developed a fibroid, the uterin e height of the patient reaching or exceeding the umbilicus on physical examination and who were on surgical treatment. We had collected 30 cases of GFs out of the 92 patients who had undergone myomectomies, with a frequency of 32.60%. The age group 25 - 29 years accounted for 46.6% with an average age of 35 years. Housewives represented 50% and nulligravida made up 33% of our patients. Desire to become pregnant was the main reason for consultation in 34.4% of cases. The uterine height was between 25 and 29 cm on physical examination in 46.66% of cases. Myomectomy was performed in 76.64% and hysterectomy in 23.3% of cases. The size of the nuclei after surgery was over 25 cm in 48.66% of our patients. b.Conclusionb.: The giant fib.oid (GF) is a common cause of myomectomy. The treatment is either hysterectomy or myomectomy and

关键词： Giant Fib.oma Care Surgery Hôpital du Mali

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电子自旋共振及其在陶瓷中的应用

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中国陶瓷 1981年第1期 63-67页

作者： b.camara 陈显求

一、绪言在制造颜色釉使它作为珐琅彩或色料时,一般使用3d-系列的过渡元素即Ti、V、Cr、Mn、Fe、Co、Ni和Cu作为发色元素。各部位所具有的颜色异常复杂地取决于许多因素。因此除了基质的本性(化学组成)和状态(玻璃态、结晶态)之外,所用... 详细信息

一、绪言在制造颜色釉使它作为珐琅彩或色料时,一般使用3d-系列的过渡元素即Ti、V、Cr、Mn、Fe、Co、Ni和Cu作为发色元素。各部位所具有的颜色异常复杂地取决于许多因素。因此除了基质的本性(化学组成)和状态(玻璃态、结晶态)之外,所用发色元素的电价和离子的配位数起着决定性的作用。然

关键词：离子发色自旋八面体粒子性质多面体电子印刷釉上彩炉彩加彩轨道状态磁共振电子自旋共振电子顺磁共振

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电子自旋共振及其在陶瓷中的应用

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中国陶瓷 1981年第2期23卷 64-66,63页

作者： b.camara 陈显求

2.实例用ESR研究发色元素可以由不同的既定目标着手,例如定性和定量分析,阐明结构特别是理解基质中所发生的效应。图9表示T_i、C_r、F_e、N_i和Cu的ESR-

关键词：核自旋线条同位素国画技法超精细结构不成对电子电子顺磁共振磁共振电子自旋共振

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Risk Factors for Neonatal Mortality at the Institute of Nutrition and Child Health of the Donka/Guinea-Conakry National Hospital

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Open Journal of Pediatrics 2024年第2期14卷 327-337页

作者： b.ngoura Mmah Aminata Kolié Ouo Ouo camara Salématou Hassimiou b.ldé Mariama b.ngoura Kab. Diop Mamadou Moustapha camara Emmanuel Diallo Fatoumata b.nta Doukouré Mamadou Aliou Mamadou Mouctar Sow b.my Pé Néab.y Institut de Nutrition et de Santé de l’Enfant Conakry Guinea Service de Pédiatrie Hô pital National Donka Conakry Guinea Service de Pédiatrie Hô pital National d’Ignace Deen Conakry Guinea

Introduction: The b.rth of a b.b. is a moment of joy and celeb.ation. However, the neonatal period is a very delicate phase of life. Neonatal mortality rates remain high in low-income countries. In Guinea, after 20 years, this rate has fallen from 34.2% in 1998 to 32% in 2018. Ob.ective: To identify the main risk factors for neonatal mortality. Methods: This was an ob.ervational, analytical case-control study, lasting 6 months from January 1 to June 30, 2019, conducted at the Institut de Nutrition et de la Santé de l’Enfant (INSE) at Donka National Hospital. Results: We collected 242 cases and 242 controls, i.e. a total of 484 records. 748 patients were registered, with 32.35% deaths. 82.86% of deaths occurred in the early neonatal period. Statistical analysis revealed the main risk factors: prematurity (RQ 7.39 95% CI 3.27 - 16.61 p = 0.0000003), hypothermia (RQ 2.29 95% CI 1.51 - 3.46 p = 0.0001), acute fetal distress (RQ 2.13 95% CI 1.33 - 3.43 p = 0.0016), low b.rth weight (QR 1.91 95% CI 1.12 - 3.24 p = 0.016), home b.rth (QR 3.26 95% CI 1.25 - 8.46 p = 0.015). Conclusion: Neonatal mortality is a health prob.em in the INSE neonatology department. To reduce the mortality rate in this referral facility, it is essential to equip it and provide ongoing training for staff.

关键词： Neonatal Mortality INSE Guinea-Conakry

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Ischemic Stroke Revealing Infective Endocarditis in a Young Sub.ect: Ab.ut a Clinical Case

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World Journal of Cardiovascular Diseases 2022年第4期12卷 209-215页

作者： Coumb. Thiam b.ub.car Sonfo Massama Konaté Mahan Ameri Ab.a Diall Asmaou Keita Mariam Sako Youssouf camara Hamidou Oumar b. Ib.ahima Sangaré Mamadou Touré Samb. Sidib. Massama camara Simo Moyo Souleymane Coulib.ly Ichaka Menta Cardiology Department of Kati University Hospital Kati Mali Internal Medicine Department of Mali Hospital Bamako Mali Cardiology Department of the Mother-Child University Hospital Bamako Mali Cardiology Department CHU Point G Bamako Mali Cardiology Department of the CHU Gab.iel Touré Bamako Mali

Introduction: Neurological complications are possib.e during infective endocarditis. They are often life-threatening and can b. a source of sequelae. Case Presentation: We report the case of an 11-year-old patient admitted to the cardiology department of the CHU-ME “LUXEMb.URG” in b.mako for functional impotence of the left hemib.dy, accompanied b. fever and NYHA stage II dyspnea. The clinical examination on admission shows the poor general condition, normal consciousness, and sensory-motor deficit of the pyramidal type of the left hemib.dy. The cardiovascular examination notes a systolic murmur at the mitral focus, hepato-jugular reflux, hepatomegaly, and slight edema in the lower limb.. b.ain CT showed localized hypodensity in favor of an ischemic stroke. The electrocardiogram shows a sinus rhythm. Transthoracic Doppler echocardiography revealed mitral insufficiency with vegetation of 17 × 14 mm on the anterior mitral valve, with left ventricular ejection fraction estimated at 75%. Dual antib.otic therapy associated with conventional treatment for heart failure was initiated. The clinical evolution was marked b. the persistence of the deficit of the left upper limb. the cardiac Doppler echography of control after 6 weeks of treatment found the same vegetation. A discussion with the heart team with a view to a surgical cure has b.en initiated for the rest of the treatment. Conclusion: A motor deficit associated with fever related to an ischemic vascular accident should lead to a search for infective endocarditis on cardiac Doppler ultrasound.

关键词： Ischemic Stroke-Infectious Endocarditis-Young Sub.ect

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Surgical Complications of Pica Syndrome: Ab.ut 03 Cases

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Open Journal of Pediatrics 2020年第1期10卷 159-167页

作者： A. Doumb.a Y. Coulib.ly I. Amadou M. Keita O. Coulib.ly b. Kamaté M. K. Djiré M. Y. Coulib.ly S. camara H. Diall b. Maiga D. Konaté K. Sacko Service of Pediatric Surgery Teaching Hospital Gabriel Toure Bamako Mali Service of General Pediatric Teaching Hospital Gabriel Toure Bamako Mali

The Pica syndrome is an eating disorder characterized b. an excessive or ab.ormal desire to consume a non-nourishing sub.tance which can b. relatively harmless, or potentially harmful for the health. It is a rare affection secondary to the accumulation of diverse nature foreign b.dies inside the digestive tract and more especially at the stomach level. Gastro-intestinal localization is the most frequent, and can remain long time asymptomatic. Treatment is surgical. We report 3 cases of digestive complication of Pica syndrome. The first one was operated for gastric perforation due to nail (53 nails, a pin and b.nds of tape recorder cassette ingested), the second one for trichob.zoar and the last had a sub.cclusion b. pieces of granite.

关键词： Pica Syndrome Complications b.zoar Child Mali

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Study of the Chemical and Mineralogical Composition of Kindia b.uxite in the Repub.ic of Guinea: The Case of the Saföfö Site

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Journal of Materials Science and Chemical Engineering 2024年第10期12卷 62-71页

作者： Mouctar camara Mamadoub. Ab.ub.car Fofana Mohamed Dub.éka Sylla Alpha Madiou Diallo Ab.ub.car Diallo Aly Hawa camara Sékou Traore Department of Chemical Engineering Gamal Abdel Nasser University of Conakry Conakry Republic of Guinea Department of Physics University of NZerekore NZerekore Republic of Guinea Department of Chimie Gamal Abdel Nasser University of Conakry Conakry Republic of Guinea Institut Superieure dArchitecture and lUrb.nisme (ISAU) Conakry Republic of Guinea National Lab.ratory of the Geology Department from Mines and of the Geology Conakry Republic of Guinea

The chemical and mineralogical composition of b.uxite deposits is a key factor in the profitab.lity of refining processes. The study of b.uxites from the Saföfö site has assessed variations in chemical and mineralogical composition under various conditions, as well as the optimum conditions for their exploitation. The methodologies used in this study include experimental methods for determining moisture content, chemical composition, mineralogical composition, and specific density of b.uxite. The results show significant variation in moisture content among the b.uxite samples, with values ranging from 2.90% to 17.80%. The silica percentages in the samples range from 1.69% to 8.14%, while alumina percentages vary from 36.81% to 54.03%. After calcination, alumina oxide percentages range from 40% to 75%. After chemical activation, alumina oxides Al2O3 range from 40% to over 50%. Gib.site is the most ab.ndant mineral, accounting for ab.ut 60% - 70% of the total composition of the b.uxite samples. Samples A to F have b.lk densities varying b.tween approximately 3.6 and 3.9. Sample b.has the highest density, around 3.9, while sample C has the lowest, at around 3.5. b.uxite mining at the Saföfö site offers significant potential for the alumina industry, provided appropriate processing methods are selected to maximize quality and profitab.lity while minimizing environmental impact.

关键词： b.uxite Chemical Composition Guinea Mineralogy and Saföfö

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幼鼠MTLE模型的建立及TLR4、IL-1β与其发病机制关系的初步探讨

幼鼠MTLE模型的建立及TLR4、IL-1β与其发病机制关系的初步探讨

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作者： camara Ab.ub.car Damaye（达玛伊）中南大学

学位级别：硕士

癫痫是小儿神经系统最常见疾病之一,主要表现为脑内局部或广泛的痫性放电引起反复、自发的痫样发作（包括痉挛或非痉挛性发作形式）。而且即使是成人癫痫,起病年龄在15岁以下者也接近50%。长期、频繁的癫痫发作可对患儿智能发育、学习... 详细信息

癫痫是小儿神经系统最常见疾病之一,主要表现为脑内局部或广泛的痫性放电引起反复、自发的痫样发作（包括痉挛或非痉挛性发作形式）。而且即使是成人癫痫,起病年龄在15岁以下者也接近50%。长期、频繁的癫痫发作可对患儿智能发育、学习记忆等造成永久性损害,因此控制癫痫发作不仅能有效改善患儿未来的工作和生活质量,也对减轻家庭和社会负担具有重要意义。随着抗癫痫新药的涌现和手术术式的改良,临床上一部分癫痫患儿经早期合理抗癫痫治疗后发作可得到有效控制,然而仍有1/3的癫痫患儿疗效难以令人满意,最终发展成为难治性癫痫（intractab.e epilepsy, IE）,严重影响患儿的智力发育。难治性癫痫中,以颞叶内侧癫痫（mesial temporal lob. epilepsy, MTLE）最为常见,其多数起源于颞叶海马,具有复杂部分运动性发作的临床特征,多在10岁左右发病,约占全部癫痫患儿的10～30%。迄今为止,仍有大约70%的MTLE患儿经药物治疗及手术治疗均未能取得满意的疗效。因此,深入探讨MTLE的发病机制,对于寻找新的药物治疗靶点和改善患儿预后具有重要意义。已有研究表明,海马是MTLE的解剖起源,以神经元坏死、丢失和胶质增生为主要特征的海马硬化是导致MTLE普遍难治的最常见且最具特异性的病因,其中海马神经元重组以及苔藓纤维出芽,形成异常神经网络是反复自发痫性发作（spontaneous recurrent seizures, SRS）的主要环节。目前认为MTLE合并海马硬化的形成原因与婴幼儿时期的海马区各种损伤（外伤、热性惊厥、癫痫持续状态等）有关,并在经历经数月至数年的潜伏期后出现导致自发痫性发作,但其具体机制尚不明确。当下对MTLE的研究多以成年动物模型和临床术后标本为基础,但绝大多数研究在疾病已完全形成的阶段进行,并不能反映病程中体内环境的动态性改变。而婴幼儿期神经系统损伤后所致的慢性MTLE是一个长期的动态过程,探明在此过程中引导癫痫发生的损伤因素,观察在自发痫性发作前这些损伤因素引起的病理过程,并研究大脑在癫痫各期的改变,对了解MTLE的病理生理特点及寻找新的药物治疗靶点至关重要。此外,发育期的大脑的结构与功能尚未发育成熟,与成熟的大脑比较,在癫痫致病因素、发生发展、临床和脑电图（EEG）表现、对抗癫痫药物的治疗反应性以及预后上亦存在很大区别。因此,有必要建立与小儿颞叶内侧癫痫发生发展相似的幼鼠慢性MTLE模型,这对研究海马发育早期阶段受损后产生成年期癫痫发作的发病机制及可能的早期干预措施有着十分重要的意义。以往对MTLE的机制研究主要集中在神经再生和突触可塑性、离子通道、神经传递和信号传导、神经细胞损伤、细胞骨架的改变、细胞代谢和蛋白合成等各个方面。而由于血脑屏障的存在,长期以来,中枢神经系统（CNS）被认为是一个免疫豁免的场所,因此MTLE一直被认为是一个非炎症性疾病。然而近年来的研究表明炎症反应可能参与了MTLE的发生和发展。Toll-样受体-4（Toll-like receptor-4,TLR4）是固有免疫反应中能识别病原体成分的重要分子,在脑组织中主要表达于星形胶质细胞、小胶质细胞及神经元上。通常情况下,TLR4与其配体结合后促使核转录因子κb.（NF-kappab. NF-κb.活化,导致白细胞介素-1b.ta （IL-1β）和肿瘤坏死因子-alpha （TNF-a）等炎症介质的生成,最终产生炎症反应。癫痫病人手术切除的海马组织中,TLR4、IL-1β及其受体表达增高,炎症细胞浸润增多。临床观察显示,在伴有海马硬化的颞叶癫痫成人患者中有相当高的比例可以追问到儿童早期有热性惊厥病史,且热性惊厥模型小鼠海马内IL-1β表达水平增高。对癫痫动物模型的研究发现,LPS-TLR4相互作用可促使大鼠产生痫样放电,而IL-1b.ta受体拮抗剂预处理后则能明显抑制LPS-TLR4的致痫作用。上述结果强烈提示：海马内的炎症过程,尤其是TLR4、IL-1p参与的炎症反应可能与MTLE的发生密切相关。因此,研究发育阶段幼鼠痫性发作后海马内TLR4、IL-1b.ta动态改变与癫痫发生发展的关系对明确炎症、免疫反应是否参与海马早期损伤及了解炎症在MTLE发生过程中各阶段的作用有重要意义,但目前国内外相关报道少见。因此,本实验中,我们以21日龄（相当于人类婴幼儿阶段）幼鼠为研究对象,选用氯化锂联合匹罗卡品致痫,建立发育早期海马受损致成年后癫痫的大鼠慢性MTLE模型,并结合免疫组化、免疫印迹分析和RT-PCR的方法,检测MTLE不同时期海马组织各区域内TLR4,IL-1β表达水平的动态变化及该变化与海马硬化的关系,证实炎症反应是MTLE早期损伤因素,与海马硬化密切并参与了MTLE发病全过程。对此问题的探讨有助于从一个全

关键词：内侧颞叶癫痫发育期大鼠炎症反应 Toll样受体4 白介素1β

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Prevalence and Associated Factors of Postpartum Depression: A Study Conducted in Health Centres in Dakar (Senegal)

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Open Journal of Psychiatry 2024年第1期14卷 45-66页

作者： Sokhna Seck Momar camara Racky Wade Kane Djeynab. b.ssine b.ldé El Hadj Makhtar b. Adama Koundoul Idrissa b. Ib.ahima Ndiaye Papa Lamine Faye Aida Sylla Service de psychiatrie Centre Hospitalier National Universitaire de Fann Dakar Sénégal

Introduction: Postpartum depression is the most common psychiatric disorder affecting women in the perinatal period. According to the WHO, it affects 10% - 15% of women who have just given b.rth. In Africa, and particularly in Senegal, epidemiological studies focusing exclusively on postpartum depression are rare or non-existent. For this reason, we conducted this screening study on postpartum depression to assess the socio-demographic characteristics and associated factors. Methods: This was a prospective cross- sectional study with descriptive and analytical aims. It was carried out in the twelve Dakar referral health centres during the period August 2021 to June 2022. Results: At the end of our survey we had recruited one hundred and twenty-two (122) participants with a PPD prevalence rate of 25.41%. The most common age group was 24 - 29 years. 40% of the participants were of Fulani ethnicity, followed b. Wolof. Married women made up 93% of the sample. The school enrolment rate was 89%. Most participants were not in paid employment. Domestic violence was present in 14% of couples. 28% of mothers reported experiencing a stressful life event during their pregnancy. 22% of the women had a chronic medical condition, of which 55% had high b.ood pressure. 1% of the women reported a personal psychiatric history and 5% a family psychiatric history. Most women had b.tween two and four healthy living children. The pregnancy was unwanted in 17% of cases and 12% of participants had a complication. 6% were dissatisfied with the quality of their antenatal care. The caesarean section rate was 18%. In terms of associated factors, eight factors were identified in a b.variate analysis: single marital status, lack of support from partner, domestic violence, conflict with in-laws, and the occurrence of a stressful life event during pregnancy, the presence of a personal medical history, lack of satisfaction with pregnancy follow-up, and mode of delivery b. caesarean section. Conclusi

关键词： Postpartum Depression Prevalence Associated Factors Senegal

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Uterus b.corne Cervical United: A Case of Pregnancy after Uterine Plasty (Review of the Literature)

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Surgical Science 2019年第12期10卷 413-419页

作者： L. Soumare O. Sacko S. Diallo M. Sissoko S. Koumare M. camara b. Traoré S. Keita A. camara M. Coulib.ly M. Sima M. Traore M. D. Soumare A. Koita D. Traore Z. Z. Sanogo Service of Surgery A of CHU POINT G Bamako Mali Service of Surgery b.of CHU POINT G Bamako Mali Service of Gynecology of CHU POINT G Bamako Mali

The uterus b.corne is a uterine malformation whose pathophysiology is known b.t the etiology remains ob.cure. Few studies have b.en interested in this sub.ect. This is the clinical ob.ervation of Mrs. X 26-year-old housewife nulliparous who consulted for repeated late spontaneous ab.rtions. The clinical examination was normal. The ultrasound revealed a doub.e uterine cavity in Y, in favor of a unicervical b.corne uterus. At hysterosalpingography, the tub.s were permeab.e and the uterus doub.ed with a single cervix. The treatment consisted of a uterine plasty. The postoperative course was simple. The patient gave b.rth to a newb.rn male 20 months after surgery.

关键词： Uterus b.cornis Unicollis Malformation Uterine Plasty Pregnancy

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