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Numerical Modeling of Mass Transfer in the Interaction between River biofilm and a Turbulent boundary Layer

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Open Journal of Fluid Dynamics 2024年第1期14卷 1-23页

作者： Falilou Coundoul Evrad M. D. Ngom Frédéric Y. moulin Institut Polytechnique de Saint-Louis Université Gaston Berger Saint-Louis Senegal Institut de Mécanique des Fluides de Toulouse UMR 5502-Université de Toulouse Occitanie France

In this article dedicated to the modeling of vertical mass transfers between the biofilm and the bulk flow, we have, in the first instance, presented the methodology used, followed by the presentation of various results obtained through analyses conducted on velocity fields, different fluxes, and overall transfer coefficients. Due to numerical constraints (resolution of relevant spatial scales), we have restricted the analysis to low Schmidt numbers (Sb>cb>b>b>=0.1, Sb>cb>b>=1, and Sb>cb>b>=10) and a single roughness Reynolds number (Reb>*b>=150). The analysis of instantaneous concentration fields from various simulations revealed logarithmic concentration profiles above the canopy. In this zone, the concentration is relatively homogeneous for longer times. The analysis of results also showed that the contribution of molecular diffusion to the total flux depends on the Schmidt number. This contribution is negligible for Schmidt numbers Sb>cb>b>≥0.1, but nearly balances the turbulent flux for Sb>cb>b>=0.1. In the canopy, the local Sherwood number, given by the ratio of the total flux (within or above the canopy) to the molecular diffusion flux at the wall, also depends on the Schmidt number and varies significantly between the canopy and the region above. The exchange velocity, a purely hydrodynamic parameter, is independent of the Schmidt number and is on the order of 10% of in the present case. This study also reveals that nutrient absorption by organisms near the wall depends on the Schmidt number. Such absorption is facilitated by lower Schmidt numbers.

关键词： Epilithic biofilm Passive Scalar Transport Direct Numerical Simulation Navier-Stokes

Efficacy of nonsolvent flower pollen extracts in healthy women with urinary incontinence:A randomized,double-blind,placebo-controlled,parallel study

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Current Urology 2024年第3期18卷 203-211页

作者： Marc moulin Erin D.Lewis David C.Crowley Colleen E.May Malkanthi Evans KGK Science Inc. LondonOntarioCanada Graminex L.L.C.SaginawMIUSA

background Urinary incontinence(UI)is a debilitating and common condition that adversely affects quality of *** and surgical approaches for managing UI symptoms may result in undesirable risks and *** randomized,double-blind,placebo-controlled,parallel study investigated the efficacy of 2 nonsolvent flower pollen extracts on UI in healthy *** and methods One-hundred and fourteen women aged 40–75 years who scored≥5 on the International Consultation on Incontinence Questionnaire-Urinary Incontinence Short Form(ICIQ-SF)were randomized to receive either Graminex®RCT Fem™UI,Graminex®Pollenberry®,or placebo for 24 *** primary outcome was the change in the ICIQ-SF score between the trial and placebo groups after 24 weeks of *** secondary outcomes included changes in the frequency of nocturia(recorded in 3-day void diaries)and 24-hour leakage volume(assessed via pad weight)after 6,12,18,and 24 weeks of supplementation and changes in stress-induced urinary leakage volume(after completion of a provocative maneuver challenge)after 24 weeks of *** All the groups demonstrated improvement in ICIQ-SF scores at week 24(pby the Pollenberry®group(−3.34±2.87)and placebo group(−2.61±3.52).The RCT Fem™UI group had corresponding improvements in 24-hour leakage volume(−17.68±39.84 g)and frequency of nocturia(−0.52±1.26)(p≤0.05).Pollenberry®supplementation significantly improved stress-induced urinary leakage volume(−7.12±15.64 g)at week *** study products demonstrated safe hematological and chemical *** RCT Fem™UI supplementation resulted in significant and clinically meaningful reductions in UI severity,with corresponding improvements in daily urinary leakage volume and frequency of ***®significantly improved stress-induced urinary leakage volume,suggesting that it may be eff

关键词： Urinary incontinence Pollen extract Healthy women Dietary supplement ICIQ-SF Urinary leakage

“实证法学”的概念术语回顾与回归--基于文献的实证法学研究整合路径

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湖湘法学评论 2024年第1期4卷 21-49页

作者：熊谋林西南财经大学法学院四川成都611130

伴随着实证研究概念和范畴的思想大讨论,法学界在过去几十年涌现出大量相关的方法或学科术语。虽然各种术语本来根植于实证研究,但由于每种术语未对既有术语作细致的文献回顾和概念分析,而呈现出术语间前后矛盾、自我否定、相互攻击、... 详细信息

伴随着实证研究概念和范畴的思想大讨论,法学界在过去几十年涌现出大量相关的方法或学科术语。虽然各种术语本来根植于实证研究,但由于每种术语未对既有术语作细致的文献回顾和概念分析,而呈现出术语间前后矛盾、自我否定、相互攻击、相互整合的泛化和分化现象。从方法和学科层面来看,要实现实证研究的发展和繁盛,就必然需要在开放和团结的学术平台下统一学术理念,“实证法学”应该是整合研究队伍的最妥当路径。将当代实证法学研究的源头定位在二十世纪八十年代,了解钱学森和吴世宦所引领的法学研究方法大讨论对实证法学的影响,可以澄清有关起源问题的误解。实证法学的传统术语在早期都包含定量和定性,近十年才因个人理解或方法偏爱引发术语之争。新兴术语虽然在定量或定性、样本大小、理念内涵、技术方法上有所差异,但都是基于实证研究发展起来的,其术语之争也源于割裂文献所致的自创概念。回归实证研究的本质,停止术语和概念之争,只要正确和恰当地定义实证法学,便可以实现整合实证法学研究的目标。

关键词：法律实证实证主义法学社科法学计量法学计算法学数量法学数据法学数字法学

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新精神活性物质“毒品化”处理的法理不兼容性研究

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辽宁公安司法管理干部学院学报 2024年第2期 2-17页

作者：熊谋林赵敏奇西南财经大学四川成都611130 成都行政学院四川成都610110

新精神活性物质长期被作为毒品看待,但这与毒品犯罪的行政犯属性相矛盾。事实上,新精神活性物质与毒品的法律属性和规范属性不在同一层面,在是否应当管制,列管的方式、边界上也与毒品有重大差异。简单地将制造、贩卖、运输新精神活性物... 详细信息

新精神活性物质长期被作为毒品看待,但这与毒品犯罪的行政犯属性相矛盾。事实上,新精神活性物质与毒品的法律属性和规范属性不在同一层面,在是否应当管制,列管的方式、边界上也与毒品有重大差异。简单地将制造、贩卖、运输新精神活性物质的行为直接认定为毒品犯罪,有违罪刑法定原则,甚至有可能违反宪法和立法法。司法实践中,已经出现涉新精神活性物质案件定性和定罪量刑的困难和矛盾,在将其认定为毒品犯罪的同时,或采用法定最低刑处理,或认定为未遂犯和不能犯。新精神活性物质与毒品并不兼容,不能将列管不明的新精神活性物质等同于毒品,更不能将未列管的物质认定为毒品。在坚持罪刑法定原则的前提下,对新精神活性物质应当秉持理性和审慎态度,跳出固有的“毒品化”思维,使其回归其药品及化学品的本质属性,这是解决新精神活性物质定罪量刑疑难问题的关键。

关键词：新精神活性物质毒品药品化学品行政犯

Dendritic spine density changes and homeostatic synaptic scaling:a meta-analysis of animal studies

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Neural Regeneration Research 2022年第1期17卷 20-24页

作者： Thiago C.moulin Danielle Rayêe Helgi b.Schiöth Functional Pharmacology Unit Department of NeuroscienceUppsala UniversityUppsalaSweden Institute of Medical biochemistry Federal University of Rio de JaneiroRio de JaneiroBrazil Institute of biomedical Sciences Federal University of Rio de JaneiroRio de JaneiroBrazil Department of Ophthalmology and Visual Sciences Albert Einstein College of MedicineNYUSA Institute for Translational Medicine and biotechnology Sechenov First Moscow State Medical UniversityMoscowRussia

Mechanisms of homeostatic plasticity promote compensatory changes of cellular excitability in response to chronic changes in the network *** type of plasticity is essential for the maintenance of brain circuits and is involved in the regulation of neural regeneration and the progress of neurodegenerative *** of the most studied homeostatic processes is synaptic scaling,where global synaptic adjustments take place to restore the neuronal firing rate to a physiological range by the modulation of synaptic receptors,neurotransmitters,and ***,despite the comprehensive literature on the electrophysiological properties of homeostatic scaling,less is known about the structural adjustments that occur in the synapses and dendritic *** this study,we performed a meta-analysis of articles investigating the effects of chronic network excitation(synaptic downscaling)or inhibition(synaptic upscaling)on the dendritic spine density of *** results indicate that spine density is consistently reduced after protocols that induce synaptic scaling,independent of the intervention ***,we discuss the implication of our findings to the current knowledge on the morphological changes induced by homeostatic plasticity.

关键词： chronic inhibition chronic stimulation dendritic spines downscaling excitability homeostatic plasticity spine density synaptic scaling upscaling

Spiritual Development as an Educational Goal

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ECNU Review of Education 2020年第3期3卷 504-518页

作者： Daniel moulin-Stozek University of Cambridge

Purpose:To inform current international debates about educating for wholeness and purpose,this article gives a critical analysis of spiritual development as a goal of state-funded schooling in England and ***/Approach/Methods:The analysis follows a history of ideas *** texts are examined to understand how notions of“spiritual”and“development”were first combined and introduced into mass education,and how they have changed over ***:The concept of spiritual development blends scientific conceptions of human development with a holistic,but ambiguous formative *** expedient,even paradoxical ideal,has resulted in confusion among practitioners and allowed for some considerable shift in ***/Value:Spiritual development in the English context provides a paradigmatic case by which to explore the integration of formative goals in the *** in some respects the English tradition of spiritual development represents something of its time and its unique cultural context,its underlying assumptions resonate with renewed international interest for educating for meaning and purpose.

关键词： Cultural curriculum development moral social spiritual

Ultrafiltration for environmental safety in shellfish production: A case of bloom emergence

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Water Science and Engineering 2021年第1期14卷 46-53页

作者： Clemence Cordier Alexandra Voulgaris Christophe Stavrakakis Patrick Sauvade Franz Coelho Philippe moulin Aix-Marseille Universite M2P2 UMR 7340Equipe Procedes MembranairesLaboratoire de Mecanique Modelisation et Procedes PropresAix en Provence 13545France Plateforme Experimentale Mollusques Marins Station Ifremer de BouinPolder des ChampsBouin 85230France Suez-Aquasource Toulouse 31029France

The process of ultrafiltration(UF)of natural seawater often encounters the problems of variation in water quality and coastal *** validate the feasibility of UF in shellfish farms,this study compared the hydraulic performance and pollutant removal efficiency of the UF process with those of the commonly used treatments that combine several filtration steps with ultraviolet(UV)*** comparison was conducted in the cases of natural seawater and a coastal *** that the UF process encountered the specific type of pollution,this study evaluated the filtration performance of the UF process and the retention of total suspended solids(TSS),bacteria,phytoplankton,and zooplankton.A real coastal bloom was considered in the case study of an experimental shellfish hatchery/nursery in *** results show that both treatments were able to eliminate approximately 50%of ***,in contrast with UV treatment combined with filtration,the UF process retained total amounts of phytoplankton,zooplankton,and bacteria in the *** the hydraulic performance of the UF process was impacted by the coastal bloom,the fouling was eliminated through chemical cleaning conducted at a frequency less than once per 12 *** the severe pollution,this study confirmed the pollution resistance and treatment performance of the UF process,indicating that UF has the potential to enhance the biosecurity level.

关键词： Ultrafiltration Environmental safety Aquaculture Shellfish culture Coastal bloom

[c2]Daisy Chain Rotaxanes as Molecular Muscles

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CCS Chemistry 2019年第1期1卷 83-96页

作者： Antoine Goujon Emilie moulin Gad Fuks Nicolas Giuseppone SAMS Research Group Institut Charles SadronCNRSUniversity of Strasbourg BP 84047Strasbourg cedex 2France

bistable[c2]daisy chain rotaxanes represent a par-ticularly intriguing class of interlocked molecules that can produce internal sliding movements with a net contraction or extension at the single-molecule level.

关键词： molecular machines supramolecular chemistry polymers responsive materials

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电能表计量无功功率的方法

电测与仪表 2004年第4期41卷 46-48页

作者： Etienne moulin 美国模拟器件公司电能计量组

总结了电能表常用的三种无功功率测量方法的定义,并根据IEC1268标准的技术条件给出了三种无功测试方法测量误差的试验数据,从而得出了低通滤波器方法测量无功功率是一种较好的方法的结论。

关键词：电能表无功功率低通滤波器测量方法测量误差