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Stem cell strategies in burns care

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Stem cell strategies in burns care

第八届全国烧伤外科学年会

作者： Burd A Ahmed K Lam S ayyappan t Division of Plastic and Reconstructive Surgery Department of SurgeryThe Chinese University of Hong KongPrince of Wales HospitalHong KongChina

the prospect of being able to replace damaged tissue by the process of regeneration would dramatically and irrevocably change the impact,management and outcome of *** current understanding of stem cell-based modulation and therapy together with their potential developments do bring this prospect ever closer to a clinical *** paper gives a background to stem cell strategies in burns care and identifies actual or prospective applications which,collectively,will forever change burns care throughout the world.

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Decompression not escharotomy in acute burns

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Decompression not escharotomy in acute burns

第八届全国烧伤外科学年会

作者： Burd A Noronha FV Ahmed K ayyappan t Division of Plastic and Reconstructive Surgery Department of SurgeryThe Chinese University of Hong KongPrince of Wales HospitalHong Kong

＜正＞the concept of escharotomy has long been associated with acute burns *** the practice of escharotomy is frequently flawed and there is considerable diversity in the teaching of the *** is proposed that there should be a fundamental change in the teaching of acute burn management and the concept of decompression should be *** justification for this change comes from a review of the present knowledge base using indexed,library and web-based information sources and also a review of a series of patients transferred to a regional burns unit over a five-year period which revealed that 37% of patients who required surgical decompression had not been appropriately treated prior to *** on relevant compartmental anatomy a change in the surgical decompression of limbs is proposed to allow safer and more effective management.

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Paediatric burn prevention:an epidemiological approach

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Paediatric burn prevention:an epidemiological approach

第八届全国烧伤外科学年会

作者： tse t Poon CH tse KH tsui tK ayyappan t Burd A Division of Plastic ＆ Reconstructive Surgery Department of SurgeryThe Chinese University of Hong KongPrince of Wales HospitalHong Kong

＜正＞OBJECtIVE:to study the mechanism of burn in hospitalized paediatric burn patients in order to develop a focused burn prevention campaign. MEtHODS:Acute paediatric burn patients were identified from the unit admi...

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transport mechanism in chemically reactive hybrid nanofluid flow containing gyrotactic micro-organisms over a curved oscillatory surface

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Applied Mathematics and Mechanics(English Edition) 2025年第1期46卷 177-192页

作者： M.NAVEED M.IMRAN t.ASGHAR Z.ABBAS Department of Mathematics Division of Science and TechnologyUniversity of Education Department of Mathematics The Islamia University of Bahawalpur

this paper examines the transport analysis, including both heat transfer and mass transfer, in hybrid nanofluid flow containing gyrotactic microorganisms towards a curved oscillatory surface. the influence of magnetic fields is also inspected in terms of their physical characteristics. to depict the phenomena of transport, modified versions of both Fick's and Fourier's laws are used. Additionally, the characteristics of both heterogeneous and homogeneous chemical reactions are also incorporated. Utilizing a curvilinear coordinate system, the flow problem is formulated as partial differential equations(PDEs)for momentum, concentration, microorganism field, and energy. An analytical solution to the obtained flow equations is achieved utilizing the homotopy analysis method(HAM).the effects of significant flow parameters on the pressure and microorganism fields, velocity, oscillation velocity, concentration, and temperature distributions are shown via graphs. Furthermore, the variations in skin friction, mass transfer rate, heat transfer rate, and local motile number due to different involved parameters are presented in tables and are analyzed in detail. Graphical results indicate that the curves of velocity and temperature fields are enhanced as the values of the solid volume fraction variables *** is also verified that the concentration rate field decreases as the values of the homogeneous reaction strength parameter and the radius of curvature parameter increase, and it increases with the Schmidt number and the heterogeneous reaction strength *** outcomes show a favorable response of the motile number to advanced values of the Peclet number, the Schmidt number, the microorganism difference parameter, and the bio-convective Lewis number.

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Association between ACtN3 R577X genotype and risk of non-contact injury in trained athletes:A systematic review

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Journal of Sport and Health Science 2023年第3期12卷 359-368页

作者： Hassane Zouhal Juan Del Coso ayyappan Jayavel Claire toumy Guillaume Ravé Nidhal Jebabli Cain C.t.Clark Benjamin Barthélémy Anthony C.Hackney Abderraouf Ben Abderrahman M2S(Laboratoire Mouvement SportSanté)-EA 1274Department of Sport SciencesUniversity of RennesRennes F-35000France Rey Juan Carlos University Centre for Sport StudiesMadrid 28032Spain SRM College of Physiotherapy SRM Institute of Science and TechnologySRM NagarKattankulathur 603203India Department of Sport Sciences University of RouenMont Saint AignanCETAPS EA 3832F-76821France toulouse Football Club Toulouse 31000France Higher Institute of Sport and Physical Education Ksar-SaidUniversity of ManoubaTunis 2010Tunisia Centre for Intelligent Healthcare Coventry UniversityCoventry CV15FBUK Department of Exercise&Sport Science Department of NutritionUniversity of North CarolinaChapel HillNC 27514USA

Purpose:the aim of this study was to review,systematically,evidence concerning the link between the ACtN3 R577X polymorphism and the rates and severity of non-contact injuries and exercise-induced muscle damage in athletes and individuals enrolled in exercise training ***:A computerized literature search was performed in the electronic databases PubMed,Web of Science,and SPORtDiscus,from inception until November *** included studies compared the epidemiological characteristics of non-contact injury between the different genotypes of the ACtN3 R577X ***:Our search identified 492 *** the screening of titles,abstracts,and full texts,13 studies examining the association between the ACtN3 genotypes and the rate and severity of non-contact injury were included in the *** studies were performed in 6 different countries(Spain,Japan,Brazil,China,the Republic of Korea,and Italy)and involved a total participant pool of 1093 *** the studies,2 studies involved only women,5 studies involved only men,and 6 studies involved both men and *** the studies included were classified as highquality studies(≥6 points in the Physiotherapy Evidence Database(PEDro)scale score).Overall,evidence suggests there is an association between the ACtN3 R577X genotype and non-contact injury in 12 *** studies observed a significant association between A CtN3 R577X polymorphism and exercise induced muscle damage:2 with non-contact ankle injury,3 with non-contact muscle injury,and 1 with overall non-contact ***:the present findings support the premise that possessing the ACtN3 XX genotype may predispose athletes to a higher probability of some non-contact injuries,such as muscle injury,ankle sprains,and higher levels of exercise-induced muscle damage.

关键词： α-actinin-3 deficiency Athletic performance Exercise-related injury Muscle injury Single nucleotide polymorphism

Fecal microbiota transplantation in allergic diseases

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World Journal of Methodology 2025年第2期15卷 83-91页

作者： Ece tüsüzÖnata ÖnerÖzdemir Division of Pediatric Allergy and Immunology Medical FacultySakarya UniversityAdapazarı54100SakaryaTürkiye

Microorganisms such as bacteria,fungi,viruses,parasites living in the human intestine constitute the human intestinal *** refers to composi-tional and quantitative changes that negatively affect healthy gut *** recent years,with the demonstration that many diseases are associated with dysbiosis,treatment strategies targeting the correction of dysbiosis in the treat-ment of these diseases have begun to be *** microbiota trans-plantation(FMt)is the process of transferring faeces from a healthy donor to another recipient in order to restore the gut microbiota and provide a therapeutic *** studies have gained popularity after probiotic,prebiotic,symbiotic studies in the treatment of dysbiosis and related *** has emerged as a potential new therapy in the treatment of allergic diseases as it is associated with the maintenance of intestinal microbiota and immunological balance(t helper 1/t helper 2 cells)and thus suppression of allergic *** this article,the definition,application,safety and use of FMt in allergic diseases will be discussed with current data.

关键词： Microbiota Dysbiosis Faecal microbiota transplantation Allergic diseases

Free vibration and transient response of double curved beams connected by intermediate straight beams

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Applied Mathematics and Mechanics(English Edition) 2025年第1期46卷 37-62页

作者： R.A.JAFARI-tALOOKOLAEI H.GHANDVAR E.JUMAEV S.KHAtIR t.CUONG-LE School of Mechanical Engineering Babol Noshirvani University of Technology Department of Mechanical Engineering Faculty of Engineering New Uzbekistan University University of Business and Science Center for Engineering Application and technology Solutions Ho Chi Minh City Open University

this paper investigates the free vibration and transient response of interconnected structures including double curved beams and intermediate straight beams,which are all constructed from functionally graded porous(FGP) materials. the strain potential and kinetic energies of each beam along with the work done by the external force are calculated. Additionally, a higher-order beam element is introduced to derive stiffness and mass matrices, along with the force vector. the curved and straight beams are discretized, and their assembled stiffness, mass matrices, and force vectors, are *** conditions at the joints are used to derive the total matrices of the entire structure. Subsequently, the natural frequencies and transient response of the system are determined. the accuracy of the mathematical model and the self-developed computer program is validated through the comparison of the obtained results with those of the existing literature and commercial software ANSYS, demonstrating excellent ***, a comprehensive study is conducted to investigate the effects of various parameters on the free vibration and transient response of the considered structure.

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Surgical site soft tissue thickness as a predictor of complications following arthroplasty

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World Journal of Methodology 2025年第2期15卷 62-73页

作者： Kevin A Wu Faheem Pottayil Crystal Jing Ankit Choudhury Albert t Anastasio Department of Orthopaedic Surgery Duke University HospitalDurhamNC 27710United States Department of Orthopaedic Surgery Medical College of Georgia at Augusta UniversityAugustaGA 30912United States Department of Orthopaedic Surgery Medical College of WisconsinMilwaukeeWI 53226United States

Appreciation of soft-tissue thickness(Stt)at surgical sites is an increasingly recognized aspect of arthroplasty procedures as it may potentially impacting postoperative *** research has focused on the predictive value of preoperative Stt measurements for complications following various forms of arthroplasty,particularly infections,across procedures such as total knee,hip,shoulder,and ankle *** studies have indicated that increased Stt is associated with a higher risk of complications,including infection and wound healing *** assessment of Stt before surgery could play a crucial role in identifying patients at a higher risk of complications and may be instru-mental in guiding preoperative planning to optimize outcomes in arthroplasty *** measurement techniques and further research are essential to enhance the reliability and clinical utility of Stt assessment for arthro-plasty surgery.

关键词： Soft-tissue thickness Arthroplasty Surgical complications total knee arthroplasty total hip arthroplasty total shoulder arthroplasty total ankle arthroplasty Preoperative assessment Wound healing Infection risk

Revealing localization and regulation of GtPase PmRab7 in lymphoid cells of Penaeus monodon after WSSV infection

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Journal of Coastal Life Medicine 2016年第11期4卷 846-851页

作者： Amrendra Kumar Vaishnavi Ramasubbu Kiran D Rasal Saravanankumar ayyappan Center for Advances Studies in Marine Biology Faculty of Marine SciencesAnnamalai UniversityParanipettaiTamilnadu 608502India ICAR-Central Institute of Freshwater Aquaculture Bhubaneswar 751002India

Objective:to identify white spot syndrome virus(WSSV)entry into the host-cells of the cultured shrimp Penaeus monodon,we have attempted to localize PmRab7(Ras-related in brain)which is playing a vital role in the WSSV ***:In this study,we have cloned PmRab7 and expressed in Escherichia coli,further purified rPmRab7 was used for antibody production,isolation of lysosomal sub-cellular fractions and western blot against lysosomal ***,high fold-change in PmRab7 regulation with increasing copy number of WSSV has been studied by using real-time ***:651 bp amplicon size gene was successfully amplified,ligated amplicon with ptZ t-tail vector confirmed by colony PCR and retriction enzyme digestion on agarose ***(pRSEt-B)651 bp gene transformed successfully in Rosetta and after 6 h of induction expressed rPmRab7 was on SDS page,furthermore soluble fraction of rPmRab7(26 kDa)was purified by ni-NtA ***7 antibody was received by Merk ***.,and western blot analysis revealed that PmRab7 is present in the lysosomal sub-cellular *** number of WSSV was increased 5 fold in 24 h and 20 fold in 72 h of infection and subsequently transcrtipt of PmRab7 was Ct=1.0 to Ct=***:Presence of PmRab7 on lysosome clearly indicating PmRab7 participating in lysosomal maturation,other hand WSSV may follow the same route of *** internalization has directly linked with regulation of PmRab7.

关键词： Penaeus monodon White spot syndrome virus PmRab7 Gene regulation