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Catatonia:“Fluctuat nec mergitur”

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World Journal of Psychiatry 2023年第5期13卷 131-137页

作者： Gabor S Ungvari stanley N Caroff Levente Csihi Gábor Gazdag Division of Psychiatry School of MedicineUniversity of Western AustraliaCrawley 6009Western AustraliaAustralia Section of Psychiatry University of Notre DameFremantle 6160Western AustraliaAustralia Department of Psychiatric Service Corporal Michael J Cresencz Veterans Affairs Medical CenterPhiladelphiaPA 19104United Department of Psychiatric Service University of Pennsylvania Perelman School of MedicinePhiladelphiaPA 19104United States Department of Psychiatry and Psychiatric Rehabilitation Jahn Ferenc South Pest HospitalBudapest 1204Hungary Department of Psychiatry and Psychotherapy Faculty of MedicineSemmelweis UniversityBudapest 1083Hungary

In the beginning of the 1900s,the prevalence of catatonia in inpatient samples was reported to be between 19.5%and 50%.From the mid-1900s,most clinicians thought that catatonia was *** in medical sciences,particularly in the field of neurology,may have reduced the incidence of neurological diseases that present with catatonic features or mitigated their *** active pharmacological and psychosocial treatment methods may have either eliminated or moderated catatonic ***,the relatively narrow descriptive features in modern classifications compared with classical texts and ascribing catatonic signs and symptoms to antipsychotic-induced motor symptoms may have contributed to an apparent decline in the incidence of *** application of catatonia rating scales introduced in the 1990s revealed significantly more symptoms than routine clinical interviews,and within a few years,the notion of the disappearance of catatonia gave way to its unexpected *** systematic investigations have found that,on average,10%of acute psychotic patients present with catatonic *** this editorial,the changes in the incidence of catatonia and the possible underlying causes are reviewed.

关键词： routine eliminated narrow

Pea3 expression promotes the invasive and metastatic potential of colorectal carcinoma

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World Journal of Gastroenterology 2014年第46期20卷 17376-17387页

作者： Aruz Mesci Samira Taeb Xiaoyong Huang Rishi Jairath Darshan Sivaloganathan stanley K Liu Faculty of Medicine University of TorontoToronto M5S 1A8Canada Sunnybrook Health Sciences Centre Sunnybrook Research InstituteToronto M4N 3M5Canada Department of Medical Biophysics University of TorontoToronto M4N 3M5Canada Department of Radiation Oncology University of TorontoToronto M5S 3E2Canada

AIM: To investigate the function of Pea3 in colorectal carcinoma (CRC) invasion and metastatic potential.

关键词： Colorectal cancer Pea3 Epithelial-mesenchymal transition Liver metastasis

Left Atrial Volume Index in Patients with Dilated Cardiomyopathy—Correlation with Left Ventricular Function

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World Journal of Cardiovascular Diseases 2016年第9期6卷 312-319页

作者： stanley George Department of Cardiology Pariyaram Medical College Kannur Kerala 670503 India

Background: The aim of this study was to determine the relation of left atrial (LA) volume and LA volume index with left ventricular function and to determine the association of duration of symptoms and left atrial volume index in patients with dilated cardiomyopathy. Materials and Methods: This was an observational, single centre study conducted in India. A total of 50 patients who were admitted to department of cardiology from July, 2008 to February, 2009 with diagnosis of dilated cardiomyopathy and an ejection fraction of <40% were included. Results: Of the 50 patients, 34 (68%) were males. 27 (54%) patients were in NYHA class II and 23 (46%) patients were in NYHA class III. LA volume was found to be ≥40 ml in all patients. LV function and LA volume were found to be correlated (r = -0.789, p < 0.01). Similarly, there was a correlation between LV function and LA volume index (r = -0.826, p < 0.01). There was no correlation between LA volume index and duration of symptoms (r = 0.04). Conclusion: It can be concluded that there is a strong inverse correlation between LA volume and left ventricular function and also between LA volume index and left ventricular function. The patients with NYHA class III were having larger left atrial volume than those with NYHA class II. Moreover, the duration of symptoms has no correlation with left atrial volume index.

关键词： Ejection Fraction Dilated Cardiomyopathy Left Atrial Volume Index Left Ventricular Function

Trade-offs and synergies of climate change adaptation strategies among smallholder farmers in sub-Saharan Africa:A systematic review

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Regional Sustainability 2021年第2期2卷 130-143页

作者： Devinia Princess Akinyi stanley Karanja Ng’ang’ Evan Hartunian Girvetz Department of Agricultural Economics and Agribusiness Management Egerton UniversityNjoro536-20107Kenya International Centre for Tropical Agriculture(CIAT) Kampala6247Uganda International Centre for Tropical Agriculture(CIAT) Nairobi823-00621Kenya

Climate change adaptation strategies provide a cushion for smallholder farmers,especially in subSaharan Africa against the risks posed by climate hazards such as droughts and ***,the decision-making process in climate adaptation is *** better understand the dynamics of the process,we strive to answer this question:what are the potential trade-offs and synergies related to decision-making and implementation of climate adaptation strategies among smallholder farmers in sub-Saharan Africa region?A systematic literature review methodology was used through the Preferred Reporting Items for Systematic Review and Meta-Analysis(PRISMA)statement with the four-stage inclusion/exclusion criteria to identify the literature from selected databases(Scopus and Google Scholar).The climate adaptation strategies are organized into five broad categories(crop management,risk management,soil/land management,water management,and livestock management strategies).Evidence suggests that potential trade-offs may arise concerning added costs,additional labor requirements,and competition among objectives or available *** synergies,on the other hand,arise from implementing two or more adaptation strategies concurrently in respect of increased productivity,resilience,yield stability,sustainability,and environmental ***-offs and synergies may also differ among the various adaptation strategies with minimum/zero tillage,comparatively,presenting more *** development and promotion of low-cost adaptation strategies and complementary climate adaptation options that minimize the trade-offs and maximize the synergies are *** and knowledge on proper implementation of climate change adaptation strategies are encouraged,especially at the local farm level.

关键词： Climate change Adaptation strategy Trade-offs Synergies Sub-Saharan Africa

Life cycle of Chetoneura shennonggongensis （Diptera： Keroplatidae： Keroplatinae） from Jiangxi Province, China

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Insect Science 2009年第4期16卷 351-359页

作者： Xue-Zhen Li Chang-Ying Niu Qiu-Ying Huang Chao-Liang Lei David W. stanley Key Laboratory of Utilization of Insect Resources and Sustainable Control of Pests Huazhong Agricultural University Wuhan China Agricultural Research Service Biological Control of Insects Research Laboratory Columbia USA

We report the first description of the biology of non-bioluminescent Keroplatidae from China. The life cycle of Chetoneura shennonggongensis is documented from laboratory culture and from field observations. The larval stage usually lasts 8-10 months. Large amounts of pupae are observed in late June, where they remain suspended horizontally or vertically from silk threads. The pupal suspending postures differ from other Keroplatidae species. Sexual differentiation is evident from the pupal stage. July is the peak time of adult emergence. Mating usually takes place immediately upon female emergence if adult males are available. The adult life span is short. Females live a maximum of 5 days and males 7 days. Egg development time varies from 20 30 days depending on environmental temperature. Larvae hang long sticky silk threads with a series of mucous droplets to capture prey. Some behaviors associated with snare construction and prey capture are also described.

关键词： Chetoneura shennonggongensis Chinese Keroplatidae life cycle

Deep Learning for Real-Time Crime Forecasting and Its Ternarization

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Chinese Annals of Mathematics,Series B 2019年第6期40卷 949-966页

作者： Bao WANG Penghang YIN Andrea Louise BERTOZZI P.Jeffrey BRANTINGHAM stanley Joel OSHER Jack XIN Department of Mathematics University of CaliforniaLos AngelesWestwoodLos AngelesCA 90095USA Department of Anthropology University of CaliforniaLos AngelesWestwoodLos AngelesCA 90095USA Department of Mathematics University of CaliforniaIrvineIrvineCA 92697USA

Real-time crime forecasting is ***,accurate prediction of when and where the next crime will happen is *** known physical model provides a reasonable approximation to such a complex *** crime data are sparse in both space and time and the signal of interests is *** this work,the authors first present a proper representation of crime *** authors then adapt the spatial temporal residual network on the well represented data to predict the distribution of crime in Los Angeles at the scale of hours in neighborhood-sized *** experiments as well as comparisons with several existing approaches to prediction demonstrate the superiority of the proposed model in terms of ***,the authors present a ternarization technique to address the resource consumption issue for its deployment in real *** work is an extension of our short conference proceeding paper[Wang,B.,Zhang,D.,Zhang,D.H.,et al.,Deep learning for real time Crime forecasting,2017,ar Xiv:1707.03340].

关键词： Crime representation Spatial-temporal deep learning Real-time forecasting Ternarization

Dynamical changes in hydration water accompanying lysozyme thermal denaturation

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Frontiers of physics 2015年第5期10卷 35-41页

作者： Francesco Mallamace Carmelo Corsaro Domenico Mallamace Nicola Cicero Sebastiano Vasi Giacomo Dugo H. Eugene stanley CNR-IPCF Messina Istituto per i Processi Chimico-Fisici Viale F. Stagno D'Alcontres 37 98158 Messina Italy Dipartimento di Fisica e Scienze della Terra Universitd di Messina Viale F. Stagno D'Alcontres 31 98166 Messina Italy Center for Polymer Studies and Department of Physics Boston University Boston MA 02215 USA Dipartimento di Scienze dell'Ambiente della Sicurezza del Territorio degli Alimenti e della Salute Universita di Messina Viale F. Stagno d'Alcontres 31 98166 Messina Italy

We study the dynanfics of the first hydration shell of lysozyme to determine the role of hydra- tion water that accompanies lysozyme thermal denaturation. We use nuclear magnetic resonance spectroscopy to investigate both the translational and rotational contributions. Data on proton self-diffusion and reorentational correlation time indicate that the kinetics of the lysozyme fold- ing/unfolding process is controlled by the dynamics of the water molecules in the first hydration shell. When the hydration water dynamics change, because of the weakening of the hydrogen bond network, the three-dimensional structure of the lysozyme is lost and denaturation is triggered. Our data indicates that at temperatures above approximately 315 K, water behaves as a simple liquid and is no longer a good solvent.

关键词： lysozyme unfolding hydration water NMR correlation time solvent dynamics

Comparison of TRMM and Water District Rain Rates over New Mexico

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Advances in Atmospheric Sciences 2006年第1期23卷 1-13页

作者： Long S. CHIU Zhong LIU Jearanai VONGSAARD stanley MORAIN Amy BUDGE Paul NEVILLE Chandra BALES NASA/Goddard Space Flight Center Distributed Active Archive Center Greenbelt Maryland 20771 USA Center for Earth Observing and Space Research School of Computational Sciences George Mason University Fairfax Virginia 22030-4444 USA Earth Data Analysis Center University of New Mexico Albuquerque New Mexico 87131 USA Thai Royal Military Academy Bangkok Thailand

This paper compares monthly and seasonal rain rates derived from the Version 5 （V5） and Version 6 （V6） TRMM Precipitation Radar （TPR, TSDIS reference 2A25）, TRMM Microwave Imager （TMI, 2A12）, TRMM Combined Instrument （TCI, 2B31）, TRMM calibrated IR rain estimates （3B42） and TRMM merged gauge and satellite analysis （3B43） algorithms over New Mexico （NM） with rain gauge analyses provided by the New Mexico water districts （WD）. The average rain rates over the NM region for 1998- 2002 are 0.91 mm d^-1 for WD and 0.75, 1.38, 1.49, 1.27, and 1.07 mm d^-1 for V5 3B43, 3B42, TMI, PR and TCA; and 0.74, 1.38, 0.87 and 0.97 mm d^-1 for V6 3B43, TMI, TPR and TCA, respectively. Comparison of V5 3B43 with WD rain rates and the daily TRMM mission index （TPR and TMI） suggests that the low bias of V5 3B43 for the wet months （summer to early fall） may be due to the non-inclusion of some rain events in the operational gauge analyses that. are used in the production of V5 3B43. Correlation analyses show that the WD rain rates vary in phase, with higher correlation between neighboring WDs. High temporal correlations （〉0.8） exist between WD and the combined algorithms （3B42, 3B43 and TCA for both V5 and V6） while satellite instrument algorithms （PR, TMI and TCI） are correlated best among themselves at the monthly scale. Paired t-tests of the monthly time series show that V5 3B42 and TMI are statistically different from the WD rain rates while no significant difference exists between WD and the other products. The agreements between the TRMM satellite and WD gauge estimates are best for the spring and fall and worst for winter and summer. The reduction in V6 TMI （-7.4%） and TPR （-31%） rain rates （compared to V5） results in better agreement between WD estimates and TMI in winter and TPR during summer.

关键词： satellite precipitation TRMM Water District New Mexico surface rain

Hepatitis B Vaccine and Immunoglobulin: Key Concepts

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Journal of Clinical and Translational Hepatology 2019年第2期7卷 165-171页

作者： Saibal Das Kirubakaran Ramakrishnan Sapan Kumar Behera Mahalakshmi Ganesapandian Alphienes stanley Xavier Sandhiya Selvarajan Department of Clinical Pharmacology Jawaharlal Institute of Postgraduate Medical Education and Research(JIPMER)PuducherryIndia

Hepatitis B virus(HBV)immunization is safe and has been accepted worldwide as a routine *** target of such vaccination is to induce the immune response in the host,resulting in the prevention of replication of *** are several immunological and clinical factors which determine the clinical efficacy and safety of the HBV *** this article we have highlighted the response of the host immune system to HBV vaccination(immunogenicity),efficacy,and safety of the vaccine,issues with booster dosing,paths of development(preclinical and clinical)of the HBV vaccine,novel and upcoming strategies for improvement of HBV vaccination,and the concept of therapeutic HBV *** different aspects and regulatory recommendations pertaining to HBV vaccine development are also *** new strategies for improvement of HBV vaccination include pre-S1 and pre-S2 portions of the HBV surface antigen,increasing the antigen dose,accelerated vaccination schedules,alternative vaccination route,use of adjuvants like immunostimulatory DNA sequences,*** vaccination is being explored for initiation of a multifunctional and multispecific T cell response against the major HBV antigens and also effective activation of humoral immunity for viral control.

关键词： Antibody Development Immune response Immunoglobulin Vaccine