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Isolated internuclear ophthalmoplegia from ischemic origin

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Journal of Acute Disease 2021年第3期10卷 133-134页

作者： Halil Onder erol Erkan Clinic of Neurology Yozgat City HospitalYozgatTurkey Clinic of Ophthalmology Yozgat City HospitalYozgatTurkey

A 67-year-old male with a medical history of hypertension,diabetes mellitus,and previous ischemic stroke applied to the neurology outpatient clinic due to acute onset double vision which had abruptly started 2 days *** neurological examination,the right eye could not adduct whereas nystagmus occurs on the left eye abduction(Figure 1).Upon history interrogation,it was learned that the patient had applied to the emergency department two days ago and cranial diffusion-weighted imaging(DWI)was performed which resulted in normal ranges(Figure 2).

关键词： acute Figure ischemic

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基于横观各向同性的沥青路面设计理论及方法

基于横观各向同性的沥青路面设计理论及方法

Transactive Demand Response Operation at the Grid Edge using the IEEE 2030.5 Standard

2007年

作者： erol Tutumlure

本书共分12章，内容包括：现行柔性路面设计理论及方法、计算理论及方法、轴对称横观各向同性层状弹性体系半空间问题、轴对称横观各向同性半无限体表面位移的解及影响因素分析等。

关键词：交通运输公路运输道路工程

来源：汇雅图书（南通市图书馆... 评论

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Engineering 2020年第7期6卷 801-811页

作者： Javad Fattahi Mikhak Samadi Melike erol-Kantarci Henry Schriemer School of Electrical Engineering and Computer Science University of OttawaOttawa ON K1N 6N5Canada

This paper presents a transactive demand response(TDR)scheme for a network of residential customers with generation assets that emphasizes interoperability within a transactive energy architecture.A complete laboratory-based implementation provides the first(to our knowledge)realization of a comprehensive TDR use case that is fully compliant with the Institute of Electrical and Electronics Engineers(IEEE)2030.5 standard,which addresses interoperability within a cybersecure smart energy profile(SEP)*** is provided by a full system integration with commercial hardware using Internet Protocol(IP)-based(local area network(LAN)and Wi-Fi)communication protocols and transport layer security(TLS)1.2 cryptographic protocol,and validation is provided by emulation using extensive residential smart meter *** demand response(DR)scheme is designed to accommodate privacy concerns,allows customers to select their DR compliance level,and provides incentives to maximize their *** proposed TDR scheme addresses privacy through the implementation of the SEP 2.0 messaging protocol between a transactive agent(TA)and home energy management system(HEMS)*** response is handled by a multi-input multi-output(MIMO)fuzzy controller that manages negotiation between the customer agent and the *** take a multi-agent system approach to neighborhood coordination,with the TA servicing multiple residences on a common transformer,and use a reward mechanism to maximize customer engagement during the event-based *** on a set of smart meter data acquired over an extended time period,we engage in multiple TDR scenarios,and demonstrate with a fully-functional IEEE 2030.5-compliant implementation that our scheme can reduce network peak power consumption by 22%under realistic conditions.

关键词： Transactive demand response IEEE 2030.5 Smart grid Multi-agent system Neighborhood coordination

伯氏疏螺旋体传播过程中病原体、媒介、宿主间的相互作用(英文)

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中国媒介生物学及控制杂志 2008年第3期19卷 264-268页

作者：宝福凯 erol Fikrig 昆明医学院基础医学院微生物学与免疫学教研室昆明650031 Sectionof Rheumatology Department of Internal MedicineYale University School of Medicine

莱姆病是一种蜱媒传播的人兽共患病,在北半球广泛流行。其病原体是伯氏疏螺旋体,具有极为复杂的传播机制和过程。在过去20多年中,科学家们对此进行了广泛而深入的探索。本综述拟对近5年这方面的研究进展,尤其是Fikrig实验室的工作进行... 详细信息

莱姆病是一种蜱媒传播的人兽共患病,在北半球广泛流行。其病原体是伯氏疏螺旋体,具有极为复杂的传播机制和过程。在过去20多年中,科学家们对此进行了广泛而深入的探索。本综述拟对近5年这方面的研究进展,尤其是Fikrig实验室的工作进行总结。内容主要包括:证明伯氏疏螺旋体外膜蛋白OspA是一种粘附素(adhesion) ,对螺旋体在硬蜱中肠(midgut)定居至关重要,并发现硬蜱中肠肠腔表面蛋白TROSPA是OspA的受体;发现蜱唾液腺蛋白Salp15协助伯氏疏螺旋体感染哺乳类动物;发现伯氏疏螺旋体膜蛋白bmpA和bmpB介导螺旋体在关节的定居及关节炎的发生。这些发现有助于我们深入了解莱姆病的传播特征和致病机制。

关键词：伯氏疏螺旋体硬蜱属哺乳类宿主分子相互作用

An Investigation of Postmortem Urotensin II Receptor Levels in Brain and Kidney Tissues in a Rat Model of Cardiac Ischemia

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Journal of Forensic Science and Medicine 2018年第1期4卷 1-6页

作者： Mustafa Talip Sener erol Akpinar Elif Cadirci Zekai Halici Irfan Cinar Ahmet Nezih Kok Departments of Forensic Medicine and Pharmacology Faculty of MedicineAtaturk UniversityErzurum 25240Turkey

This study aimed to investigate changes in postmortem urotensin Ⅱ receptor(UTR)levels in brain and kidney tissues in a rat model of cardiac *** rats were divided into two groups:a control group and a cardiac ischemia-induced *** ischemia was created by an intraperitoneal injection of a single lethal dose of isoproterenol(ISO;850 mg/kg).Plasma UT,blood urea nitrogen,and creatinine levels were determined 0 h *** and kidney UTR mRNA expression levels were determined 0,1,3,6,12,24,4&and 72 h *** histopathological appearance of brain and kidney tissues was also *** UT and plasma creatinine levels were increased in the cardiac ischemia-induced group as compared with those in the control group(P<0.001).Ischemia resulted in histopathological changes in brain and cerebellum *** morphological evaluation revealed Purkinje cell degeneration(P=0.037)and dark neurons(P=0.004).The UTR expression level decreased after 1 h postmortem in the brain and after 3 h postmortem in the kidneys in the cardiac ischemia-induced group as compared with that in the control group(P<0.001).The observed changes in UTR expression levels may be valuable in clinical practice in the field of forensic *** changes may be used as a marker in postmortem evaluations of sudden death caused by ischemia-induced cardiac shock.

关键词： Brain cardiac ischemia kidney postmortem urotensin II receptor expression

Paroxetine overdose during pregnancy

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Forensic Sciences Research 2021年第4期6卷 237-239页

作者： Selin Acar Hilal erol Elif Keskin Arslan Nusret Uysal BarışKaradaş Tijen Kaya Temiz Yusuf Cem Kaplan Faculty of Medicine Department of Pharmacologyizmir Katip celebi UniversityizmirTurkey Terafar(izmir Katip celebi University Teratology information Training and research center)izmirTurkey

Paroxetine is a selective serotonin reuptake inhibitor(SSRI)used in the treatment of depression and anxiety *** some epidemiological studies,slightly increased risks of major malformations and cardiac malformations have been reported following paroxetine exposure in the first trimester of ***,such findings have been *** is only one report of any overdose of an SSRI during pregnancy,and that involved *** aim of this case report was to describe the impact of a paroxetine overdose in the first trimester of pregnancy on the health of the foetus.A 21-year-old mother of one child who was pregnant with a second child was prescribed 20 mg/day paroxetine hydrochloride for the treatment of anxiety/*** patient ingested 15 or 1620-mg tablets of paroxetine hydrochloride(300-320 mg)during the 5th week of pregnancy as a suicide *** 15 min of ingestion,she was admitted to hospital and treated for *** evidence of maternal SSRI intoxication was observed after *** patient consulted our teratology information service for further risk assessment regarding possible major congenital malformations following the paroxetine *** were unable to find previous reports of paroxetine overdose during pregnancy in the *** timely administration of the overdose treatment and the lack of maternal intoxication symptoms were considered positive for the foetal well-being,and the patient was referred for perinatology and psychiatry follow-ups.A healthy,3500-g male infant was born at 38 weeks’gestation,and his development at the age of 2 years was *** is the first reported case of paroxetine overdose during *** studies are needed to evaluate pregnancy outcomes after SSRI overdose.

关键词： Forensic sciences forensic toxicology paroxetine overdose teratogenicity case report

A novel mutation of SGK-1 gene in central serous chorioretinopathy

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International Journal of Ophthalmology(English edition) 2015年第1期8卷 23-28页

作者： Mahmut Akyol Muhammet Kazιm erol Ozdemir Ozdemir Deniz Turgut Coban Ahmet Burak Bilgin Esin Sogutlu Sari Elif Betul Turkoglu Department of Medical Biology and Genetics Akdeniz University Faculty of Medicine Department of Ophthalmology Antalya Education and Research Hospital Department of Ophthalmology Zekai Tahir Burak Women's Health Education and Research Hospital Department of Ophthalmology Akdeniz University Faculty of Medicine Department of Ophthalmology Balιkesir University Faculty of Medicine

AIM: To investigate the association of serum glucocorticoid kinase gene-1(SGK-1) DNA variants with chronic central serous chorioretinopathy(CSC).METHODS: We enrolled 32 eyes of 32 patients who were diagnosed with chronic CSC and composed 32 normal eyes as a control group. Peripheral blood was used for DNA extraction and polymerase chain reaction amplification. SGK1 gene was sequenced by using Big Dye Terminator v3.1 cycle sequencing Kit(Applied Biosystems, Foster City, CA, USA). The SGK-1 gene and its variants were investigated in CSC patient group and control ***: We identified a new polymorphism M32 V in two person in the patient group [Minor allele frequency(MAF) =0.009] on the region of 1-60 amino acids. The rs1057293 was located in the encoder region of the SGK- 1 gene but not associated with CSC(P =0.68). An intrinsic rs1743966 is also not associated(P =0.28).CONCLUSION: The new polymorphism M32 V is located on the region of 1-60 amino acids which is necessary for localization to the mitochondria in CSC patient. This mutation is probably important for the energy metabolism and plays an important role in the cellular response to hyperosmotic stress and other stress stimuli. Both rs1057293 and rs1743966 are not associated with CSC.

关键词： central serous chorioretinopathy mutation polymerase chain reaction serum glucocorticoid kinase gene-1

Bullous oral lichen planus:report of two cases

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中华医学杂志(英文版) 2003年第10期 154-155页

作者： Berrin NSAL,S.Elif GLTEKIN,erol BAL,Benay TOKMAN Department of Periodentology Faculty of Dentistry Gazi University Department of Oral Pathology Faculty of Dentistry Gazi University Department of Maxillofacial Surgery Dental Clinic Air Force Hospital Etimesgut Department of Oral Pathology Faculty of Dentistry Gazi University Ankara Turkey Ankara Turkey Ankara Turkey Ankara Turkey

Outcome of surgical treatment of intestinal perforation in typhoid fever

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World Journal of Gastroenterology 2010年第33期16卷 4164-4168页

作者： Aziz Sümer zgür Kemik Ahmet Cumhur Dülger Aydemir Olmez Ismail Hasirci erol Kisli Vedat Bayrak Gulay Bulut etin Kotan Department of General Surgery Medical FacultyUniversity of YüzüncüY1l Department of Gastroenterology Medical FacultyUniversity of YüzüncüY1l Department of Pathology Medical FacultyUniversity of YüzüncüY1l

AIM:To represent our clinical experience in the treatment of intestinal perforation arising from typhoid ***:The records of 22 surgically-treated patients with typhoid intestinal perforation were evaluated ***:There were 18 males and 4 females,mean age 37 years(range,8-64 years).Presenting symptoms were fever,abdominal pain,diarrhea or *** cases were subjected to segmental resection and end-to-end anastomosis,while 3 cases received 2-layered primary repair following debridement,one case with multiple perforations received 2-layered primary repair and end ileostomy,one case received segmental resection and end-to-end anastomosis followed by an end ileostomy,and one case received segmental resection and end ileostomy with mucous fistula *** morbidity was seen in 5 cases and mortality was found in one ***:Intestinal perforation resulting from Salmonella typhi is an important health problem in Eastern and Southeastern *** management of this illness,early and appropriate surgical intervention is vital.

关键词： Intestinal perforation Typhoid fever Treat- ment