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Expression Patterns of CAPN1 and CAPN8b Genes during Embryogenesis in Xenopus laevis

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CellBio 2013年第4期2卷 211-216页

作者： lucie Abrouk-Vérot Claire Brun Jean-Marie Exbrayat Université de Lyon UMRS 449 Biologie Générale Université Catholique de Lyon Reproduction et Développement Comparé Ecole Pratique des Hautes Etudes Lyon France

Calpains are a superfamily of Ca2+-dependent cysteine proteases, implicated in various cellular processes and thus probably necessary in all the stages of cell life. The first extended report of quantification of total RNAs within the developmental stages of Xenopus laevis was described in this study. Decreases of total RNAs were positively associated with waves of apoptotic cell death (onset of gastrulation, and morphogenesis). Using qPCR, the temporal expression pattern of CAPN1 and CPAN8b (XCL-2) were characterized during the Xenopus laevis embryogenesis. Transcripts of the CAPN1 and CAPN8 genes were detectable from gastrula stage and their levels oscillated throughout development. The expression of the CAPN1 (mu/I) gene was observed in earliest stage, indicating a maternal origin, while expression of the CAPN8b gene was detectable after midblastula transition. The levels of the two transcripts then started to rise again obviously as a result of zygotic expression (stage 11). The CAPN1 gene expression was particularly expressed at tailbud stage, while the CAPN8 transcripts were found at gastrula, neurula and tailbud stages. This is the first report of quantification of mRNAs CAPN8b and CAPN1 (mu/I) within the developmental stages of Xenopus laevis by qPCR.

关键词： Calpain Embryonic Development Cell Death Xenopus laevis

sTREM-1 is a specific biomarker of TREM-1 pathway activation

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Cellular & Molecular Immunology 2021年第8期18卷 2054-2056页

作者： lucie Jolly Kévin Carrasco Margarita Salcedo-Magguilli Jean-Jacques Garaud Simon Lambden Tom van der Poll Alexandre Mebazaa Pierre-François Laterre Sebastien Gibot Amir Boufenzer Marc Derive Inotrem Vandœuvre-lès-NancyFrance Division of Infectious Diseases Amsterdam University Medical CentersUniversity of AmsterdamAmsterdamThe Netherlands Intensive Care Unit Saint Louis-Lariboisière-Fernand Widal University HospitalAssistance Publique Hôpitaux de Parisand Universitéde ParisInserm MASCOTParisFrance Intensive Care Unit UniversitéCatholique de LouvainLouvain-la-NeuveBelgium Intensive Care Unit CHRU de Nancyand Universitéde LorraineNancyFrance

TREM-1(triggering receptor expressed on myeloid cells-1)is a transmembrane receptor expressed by innate immune cells,including endothelial cells and ***-1 is a crucial mediator of septic shock that acts by synergizing with Toll-like receptors(TLRs)to amplify the inflammatory responses to pathogens,thus promoting sepsis-induced immune dysregulation and organ dysfunction[1,2,3].

关键词： immune myeloid activation

Land Use and Land Cover Change Analysis in Ajei Upland Watershed Community Forest, North West Region, Cameroon

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Journal of Geoscience and Environment Protection 2018年第9期6卷 83-99页

作者： lucie Félicité Temgoua Gordon Ajonina Hans Berinyuy Woyu Department of forestry Faculty of Agronomy and Agricultural Sciences University of Dschang Dschang Cameroon Cameroon Wildlife Conservation Society Mouanko Cameroon

This study was carried out in Ajei upland watershed community forest in the North West Region of Cameroon with the aim to analyze spatial and temporal dynamics of land cover and land use from 1988 to 2018 and to identify and characterize the agents, drivers and pressures of this change. The databases used were made up of 3 Lands at satellite images (5 TM of 1988, 7ETM+ of 2003 and 8OLI of 2018). Field survey, interview and focus group discussion methods were used to identify the activities carried out by the local population and to determine agents, drivers and pressures of land use and land cover change. The Ajei community forest is consisted of four main land cover namely;dense vegetation, sparse or degraded vegetation, savanna and bare soil. Between 1988 and 2018, the proportions of dense vegetation and savanna decreased and that of bare soil and sparse vegetation increased. Analysis showed ongoing deforestation with forest cover loss of about 240 ha in 30 years. For the considered time periods 1988-2003 and 2003-2018, deforestation rates were 1.83% per year and 1.49% per year respectively, signifying on average 8 hectares of forest cover undergoing conversion each year. This lost results from the actions of farmers, cattle grazers and wood extractors who through farming, grazing and lumbering activities pressurize and convert the dense forest cover. Economic motives notably the need to increase household income from a frequent demand for farm and wood products in nearby markets represent the drivers of forest cover change. Controlling grazing activities notably in the dry season to check out the use of fires, community sensitization especially among cattle headmen on the importance of the community forest, reforestation activities through natural regeneration or tree planting are needed in the forest.

关键词： Land Use Land Cover Change Agents Drivers Pressures

Determining the Relative Age of Fault Activity through Analyses of Gouge Mineralogy and Geochemistry: A Case Study from Vápenná(Rychleby Mts), Czech Republic

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International Journal of Geosciences 2010年第2期1卷 66-69页

作者： lucie Nováková Pavel Hájek Martin Stastny 不详

The relative age of fractures can be determined through structural analyses in the field or through the detailed mineralogical (XRD) and chemical analyses (AAS method, volumetric, and gravimetric analysis) of fault gouge in the laboratory. The aim of this work was to compare these approaches. It was hypothesised that the two methods would yield consistent results. The studied faults were located in the Rychleby Mts, part of the Sudetic Marginal Fault Zone. The relative age of the faults was determined in the field through the application of the intersection law. The fault gouges were sampled in a crystalline limestone quarry near the village of Vápenná. The mineralogical composition of the fault gouges has been established by XRD analysis of powder samples and analysis of preferentially oriented clay minerals. From our result, it is clear that these two approaches yielded consistent results with regard to the relative age of the faults.

关键词： Crystalline Limestone Intersecting Faults Fault Gouge Relative Chronology

Relationship between Perceived over Qualification,knowledge Sharing and Job Performance: Moderating Role of Exchange Ideology

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Relationship between Perceived over Qualification,knowledge ...

作者： Razafitsotra Soanomenjanahary lucie Annie Delia 浙江工商大学

学位级别：硕士

The context of perceived over qualification has become a popular discussion and frequently studied by many *** researches and findings comprise the significance of knowledge sharing in knowledge ***,there is still a troubling issue in the unwillingness of employees to share *** workers acquire an increasing amount of information related to their workplace,some individuals may be reluctant to *** present study aims to assess that exchange ideology moderates the interaction of perceived over qualification（POQ）and Job performance（JP）.Exchange ideology（IE）indicate the employee’s wiliness to support and reciprocate work effort depending on the organization’s *** organization’s support motivates employees to engage in a strong exchange ideology towards the workplace and initiate self-decision to give and receive in an exchange relationship with the *** have demonstrated that positive effects are clearly related to increase intrinsic *** are countless reasons supposed to enhance an individual’s experiences of interest and self-satisfaction *** studies also have revealed some portion of motivating aspects like a history of knowledge-sharing *** has identified the fundamental role of intrinsic motivation by clarifying its positive outcomes in human *** present study displays a conceptual framework from a logical perspective of perceived over qualification to explore the plausible contribution of exchange ideology on POQ（perceived over qualification）,and JP（job performance）.In present research,we assume that workers who are overqualified have higher availability skills also provide high performance at ***,two critical conditions are combined to demonstrate relationship between the ***,I propose that perceived over qualification relate to knowledge sharing in a positive *** with surplus qualification are self-ass

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Zinc phosphate-based nanoparticles as alternatives to zinc oxide in diet of weaned piglets

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Journal of Animal Science and Biotechnology 2020年第4期11卷 1147-1162页

作者： Silvia Kociova Kristyna Dolezelikova Pavel Horky Sylvie Skalickova Daria Baholet lucie Bozdechova Eva Vaclavkova Jaroslava Belkova Pavel Nevrkla Jiri Skladanka Tomas Do Ondrej Zitka Yazan Haddad Pavel Kopel Ludek Zurek Vojtech Adam Kristyna Smerkova Department of Chemistry and Biochemistry Mendel University in BrnoZemedelska 1CZ-61300 BrnoCzech Republic Central European Institute of Technology Brno University of TechnologyPurkynova 123CZ-61200 BrnoCzech Republic Department of Animal Nutrition and Forage Production Mendel University in BrnoZemedelska 1CZ-61300 BrnoCzech Republic Institute of Animal Science Pratelstvi 815CZ-10400 Praha UhrinevesCzech Republic Department of Animal Breeding Mendel University in BrnoZemedelska 1CZ-61300 BrnoCzech Republic Department of Inorganic Chemistry Faculty of SciencePalacky University17.listopadu 12CZ-77146 OlomoucCzech Republic Central European Institute of Technology Center for ZoonosesUniversity of Veterinary and Pharmaceutical SciencesBrnoPalackeho 1946/1CZ-61242 BrnoCzech Republic.

Background: The high doses of zinc oxide(Zn O) administered orally to piglets for the prevention of diarrhea and increase of growth rate can contaminate pig farms and the surrounding environment. Therefore, there is a need to find a replacement of high doses of dietary Zn O with an equally effective alternative. In the present study, the effect of two formulations of zinc phosphate-based nanoparticles(Zn A and Zn C NPs) on growth performance,intestinal microbiota, antioxidant status, and intestinal and liver morphology was evaluated. A total of 100 weaned piglets were randomly divided into 10 equal groups with the base diet(control) or the base diet supplemented with Zn A, Zn C, or Zn O at concentrations 500, 1000, and 2000 mg Zn per kilogram of diet. Supplements were given to animals for 10 days. Fecal samples were collected on day 0, 5, 10 and 20. At the end of the treatment(day 10),three piglets from each group were sacrificed and ***: Comparing to that of control, the significantly higher piglet weight gain was observed in all piglet groups fed with Zn A(P < 0.05). Differences in the total aerobic bacteria and coliform counts in piglet feces after NPs supplementation compared to that of control and Zn O groups were also found(P < 0.05). The majority of aerobic culturable bacteria from the feces represented Escherichia(28.57–47.62%), Enterococcus(3.85–35.71%), and Streptococcus(3.70–42.31%) spp. A total of 542 Escherichia coli isolates were screened for the virulence genes STa,STb, Stx2, F4, and F18. The substantial occurrence of E. coli virulence factors was found on day 5, mainly in fimbrillary antigen and thermostable toxins, except for piglets fed by Zn C. Zn treatment decreased Zn blood levels in piglets fed with Zn O and Zn A(500 mg/kg) and increased in Zn C(2000 mg/kg) compared to that of control(P < 0.05). The antioxidant status of piglets was affected only by Zn A. While some changes in the liver and the intestinal morphology of piglets with

关键词： Antioxidant status Diet E.coli STa STb Stx2 F4 F18 Fecal coliforms Microbiota

The Advanced Approaches to Nutritional and Breadmaking Quality of Wheat, Barley and Rye Flour

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Journal of Food Science and Engineering 2012年第4期2卷 218-226页

作者： Marcela Slukova Nikoleta Velebna lucie Krejcirova Iva Honcu Eva Budilova Department of Carbohydrate Chemistry and Technology Institute of Chemical Technology Prague Technicka 5 Prague 6 166 28Czech Republic

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德国可爱圣诞家饰

家纺时代 2013年第2期 100-105页

作者： lucie

我们国家不是一个宗教文化占主导地位的国家，圣诞节对于很多人来说印象仅仅停留在圣诞老人这个画面上。基督教的文化，圣经的故事对于信教者来说显然不会感到陌生，可是对于不信教的很多国人来说就是个新的认知领域了。

关键词：圣诞老人可爱德国宗教文化认知领域圣诞节基督教国家

Diversity of shifting cultivation cycles among small-scale farmers in Peruvian Amazon

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Agricultural Sciences 2011年第2期2卷 68-77页

作者： Bohdan Lojka Jan Banout lucie Banoutova Vladimir Verner Patrick Van Damme 不详

Although shifting cultivation is practiced by millions of farmers, it is often blamed for caus-ing deforestation and keeping farmers in pov-erty. Our study focused on the Amazon basin, where small-scale farmers widely practice shift- ing cultivation. The objective was to identify the diversity in land use after initial slash-and- burn land clearing among migrant peasants. Our research aimed at documenting typical crop sequences, plant species composition and specific lengths of particular phases of shifting cultivation cycles on the basis of farmers re-lated field histories. Land use was examined in two settlements: Antonio Raimondi and Pimen-tal in Ucayali region, Peru. Data was gathered via semi-structured questionnaires that focused on the socio-demographic characterization of agriculture-dependent households and their land use characteristics. More in-depth as-sessments of crop occurrence, cropping se-quence and length of the different shifting cul-tivation cycles were conducted on 114 fields in Pimental and 44 fields in Antonio Raimondi. In-terview analysis showed that in both villages, forest cover has substantially decreased over the last 10 years. Results also indicate consid-erable variation in swidden-fallow systems. Whereas settlers in Antonio Raimondi plant annual crops after slashing and burning the forest, settlers in Pimental gave more impor-tance to perennial crops. Progress in deforesta-tion and land degradation is relatively more pronounced in the younger settlement (Antonio Raimondi). These differences are likely caused by the different social backgrounds of settlers and histories of each site. Small-scale farmers in the study area are now facing a problem with the transition from shifting cultivation to sed-entary farming. Farmers in areas with a preva-lence of annual cropping use a significantly shorter fallow period, which causes a higher rate of forest degradation. As annual cropping seems to be unsustainable in relation with for-est degradati

关键词： Agroforestry Deforestation Land Degradation Slash-And-Burn Swidden-Fallow