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Surgical and long-term functional outcomes of patients with Duchenne muscular dystrophy following spinal deformity correction

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World Journal of Orthopedics 2023年第6期14卷 411-426页

作者： Simon Roberts ayesha arshad Athanasios I Tsirikos Department of Spinal Surgery Leeds Teaching Hospitals NHS TrustLeeds LS13EXUnited Kingdom Scottish National Spine Deformity Centre Royal Hospital for Children and Young PeopleEdinburgh EH164TJUnited Kingdom

BACKGROUND Life expectancy in patients with Duchenne muscular dystrophy(DMD)has improved due to advances in medical *** patients develop progressive spinal deformity after loss of ambulatory function and onset of wheelchair dependence for *** is limited published data on the effect of spinal deformity correction on long-term functional outcomes,quality of life(QoL),and satisfaction in DMD *** To investigate the long-term functional outcomes following spinal deformity correction in DMD *** This was a retrospective cohort study from *** was collected from hospital records and *** follow-up,patients completed the muscular dystrophy spine questionnaire(MDSQ).Statistical analysis was performed by linear regression analysis and ANOVA to analyse clinical and radiographic factors significantly associated with MDSQ *** Forty-three patients were included with mean age 14.4 years at *** fusion was performed in 41.9%of *** surgical time was 352.1 min and mean blood loss was 36%of estimated total blood *** hospital stay was 14.1 *** complications occurred in 25.6%of *** preoperative scoliosis was 58°,pelvic obliquity 16.4°,thoracic kyphosis 55.8°,lumbar lordosis 11.1°,coronal balance 3.8 cm,and sagittal balance+6.1 *** surgical correction of scoliosis was 79.2%and of pelvic obliquity was 80.8%.Mean follow-up was 10.9 years(range:2-22.5).Twenty-four patients had died at *** patients completed the MDSQ at mean age 25.4 years(range 15.2-37.3).Two patients were bed-ridden and 7 were on ventilatory *** MDSQ total score was *** 16 patients were satisfied with the results of spinal surgery and would choose surgery again if *** patients(87.5%)reported no severe back pain at *** significantly associated with functional outcomes(MDSQ total score)included greater duration of post-operative follow-up,age,scolios

关键词： Duchenne muscular dystrophy Scoliosis Surgical Functional Outcomes

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Disparities in esophageal cancer incidence and esophageal adenocarcinoma mortality in the United States over the last 25-40 years

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World Journal of Gastrointestinal Endoscopy 2023年第12期15卷 715-724页

作者： Hafiz Muhammad Sharjeel arshad Umer Farooq ayesha Cheema ayesha arshad Muaaz Masood Kenneth J Vega Division of Gastroenterology&Hepatology Augusta University-Medical College of GeorgiaAugustaGA 30912United States Department of Internal Medicine Loyola Medicine/MacNeil HospitalBerwynIL 60402United States Department of Medicine Fatima Memorial Medical CollegeLahore 54000PunjabPakistan Department of Medicine Augusta University-Medical College of GeorgiaAugustaGA 30912United States

BACKGROUND Esophageal carcinoma presents as 2 types,esophageal adenocarcinoma(EAC)and esophageal squamous cell carcinoma(ESCC)with the frequency of both changing in the United States(US).AIM To investigate EAC/ESCC incidence time trends among the 3 main US racial groups and investigate trends in US EAC survival by *** Twenty-five years(1992-2016)of data from SEER 13 program was analyzed to compare incidence trends in EAC and ESCC between non-Hispanic whites(nHW),non-Hispanic Blacks(nHB)and Hispanics(Hisp)using SEERStat®.In addition,SEER 18 data,from 1975-2015,on EAC in the US was analyzed to evaluate racial disparities in incidence and survival using SEERStat®and Ederer II *** In the 3 major US ethnic groups,age-adjusted incidence of ESCC has declined while EAC has continued to rise from *** note,in Hisp,the EAC incidence rate increased while ESCC decreased from 1992 to 2016,resulting in EAC as the predominant esophageal cancer subtype in this group since 2011,joining ***,although ESCC remains the predominant tumor in nHB,the difference between ESCC and EAC has narrowed dramatically over 25 *** survival probabilities were worse in all minority groups compared to *** Hisp have joined nHW as US ethnic groups more likely to have EAC than *** note,EAC incidence in nHB is increasing at the highest rate *** lower EAC incidence in all minority groups compared to nHW,these populations have decreased survival compared to nHW.

关键词： Esophageal carcinoma Ethnicity Incidence Survival Disparity Race

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Cloud authorization： exploring techniques and approach towards effective access control framework

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Frontiers of Computer Science 2015年第2期9卷 297-321页

作者： Rahat MASOOD Muhammad Awais SHIBLI Yumna GHAZI ayesha KANWAL arshad ALI School of Electrical Engineering and Computer Science (SEECS) National University of Sciences and Technology (NUST) Islamabad - 44000 Pakistan

Despite the various attractive features that Cloud has to offer, the rate of Cloud migration is rather slow, pri- marily due to the serious security and privacy issues that exist in the paradigm. One of the main problems in this regard is that of authorization in the Cloud environment, which is the focus of our research. In this paper, we present a systematic analysis of the existing authorization solutions in Cloud and evaluate their effectiveness against well-established industrial standards that conform to the unique access control require- ments in the domain. Our analysis can benefit organizations by helping them decide the best authorization technique for deployment in Cloud; a case study along with simulation re- sults is also presented to illustrate the procedure of using our qualitative analysis for the selection of an appropriate tech- nique, as per Cloud consumer requirements. From the results of this evaluation, we derive the general shortcomings of the extant access control techniques that are keeping them from providing successful authorization and, therefore, widely adopted by the Cloud community. To that end, we enumer- ate the features an ideal access control mechanisms for the Cloud should have, and combine them to suggest the ultimate solution to this major security challenge - access control as a service （ACaaS） for the software as a service （SaaS） layer. We conclude that a meticulous research is needed to incorpo- rate the identified authorization features into a generic ACaaS framework that should be adequate for providing high level of extensibility and security by integrating multiple accesscontrol models.

关键词： authorization access control software as a ser-vice extensible access control markup language identity &access management cloud security

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Evaluation of soil loss severity and ecological restoration approach for sustainable agriculture in the Hindu Kush, Karakoram and Himalaya region

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Journal of Mountain Science 2024年第5期21卷 1509-1521页

作者： arshad ASHRAF Imran AHMAD Climate Energy and Water Research InstituteNational Agricultural Research Centre(NARC)Islamabad 44000Pakistan

Soil erosion has resulted in removal of the topsoils containing fine soil particles and plant nutrients, causing decrease in soil fertility in the Hindu Kush, Karakoram and Himalaya(HKH) region. The existing production of cereal crop grains has been reduced to one third of the potential crop grains production owing to land degradation and poor farming practices. It is necessary to assess risk of soil loss and identify appropriate controlling measures to address issues of low agriculture productivity and water insecurity in the region. In the present study, severity of soil loss was predicted using Revised Universal Loss Equation(RUSLE) and ecological measures were identified for sustainable mountain agriculture in the HKH region of Upper Indus Basin, Pakistan. Overall 62.6% area was found to have very low risk of soil loss, i.e., 100 t/(ha·yr) in about 6.8% and 7.4% areas respectively. The mean rate of soil loss was about 41.9 t/(ha·yr) in the Hindu Kush, 31.1 t/(ha·yr) in the Himalayas, 18.8 t/(ha·yr) in the Karakoram and overall 29.7 t/(ha·yr) in the three HKH ranges. As such no considerable measures have been adopted by the communities for restoration of the degraded areas except raising fruit/farm trees and supporting limited social forestry for their livelihoods. The slopes cleared for cultivation and susceptible to erosion may be stabilized through sowing/planting of multi-purpose plant species and formation of proper bench terraces. The conservation of forest ecosystem and pastures at higher elevations would help in reducing overland water flow, risk of flash flood hazard and minimizing sediment loads in the downstream. It is essential to adopt site-specific resource conservation techniques and restore possible ecosystem health for sustainable agriculture and economic developm

关键词： Climate change Erodibility Indus basin Land degradation Slope stabilization

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ROBO-SPOT:Detecting Robocalls by Understanding User Engagement and Connectivity Graph

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Big Data Mining and Analytics 2024年第2期7卷 340-356页

作者： Muhammad Ajmal Azad Junaid arshad Farhan Riaz College of Comnputer Science Birmingham City UniversityBirminghamB55JUUK School of Computer Science University of LincolnLincolnLN67TSUK

Robo or unsolicited calls have become a persistent issue in telecommunication networks,posing significant challenges to individuals,businesses,and regulatory *** calls not only trick users into disclosing their private and financial information,but also affect their productivity through unwanted phone ringing.A proactive approach to identify and block such unsolicited calls is essential to protect users and service providers from potential ***,this paper proposes a solution to identify robo-callers in the telephony network utilising a set of novel features to evaluate the trustworthiness of callers in a *** trust score of the callers is then used along with machine learning models to classify them as legitimate or *** use a large anonymized dataset(call detailed records)from a large telecommunication provider containing more than 1 billion records collected over 10 *** have conducted extensive evaluation demonstrating that the proposed approach achieves high accuracy and detection rate whilst minimizing the error ***,the proposed features when used collectively achieve a true-positive rate of around 97%with a false-positive rate of less than 0.01%.

关键词： social network analysis reputation unwanted calls robo-callers telephone network Spam Over Internet Technology(SPIT)

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Aberrant adult neurogenesis in intractable epilepsy:can GABAergic progenitor transplantation normalize this process?

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Neural Regeneration Research 2024年第7期19卷 1419-1420页

作者： Muhammad N.arshad Janice R.Naegele Department of Biology Wesleyan UniversityMiddletownCTUSA Department of Neuroscience Tufts University School of MedicineBostonMAUSA

Temporal lobe epilepsy(TLE) is a common type of focal epilepsy characterized by seizure foci within the temporal *** surgical resection of the foci is an established and effective approach for controlling seizures,both temporal lobes cannot be removed,due to their prominent roles in learning and ***,seizures induce changes to the temporal lobes that contribute to hyperexcitability,including mossy fiber sprouting,astrogliosis.

关键词： epilepsy progenitor seizures

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Predicting Age and Gender in Author Profiling: A Multi-Feature Exploration

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Computers, Materials & Continua 2024年第5期79卷 3333-3353页

作者： Aiman Muhammad arshad Bilal Khan Sadique Ahmad Muhammad Asim Department of Computer Science City University of Science and Information TechnologyPeshawar25000Pakistan EIAS:Data Science and Blockchain Laboratory College of Computer and Information SciencesPrince Sultan UniversityRiyadh11586Saudi Arabia School of Computer Science and Technology Guangdong University of TechnologyGuangzhou510006China

Author Profiling (AP) is a subsection of digital forensics that focuses on the detection of the author’s personalinformation, such as age, gender, occupation, and education, based on various linguistic features, e.g., stylistic,semantic, and syntactic. The importance of AP lies in various fields, including forensics, security, medicine, andmarketing. In previous studies, many works have been done using different languages, e.g., English, Arabic, French,***, the research on RomanUrdu is not up to the ***, this study focuses on detecting the author’sage and gender based on Roman Urdu text messages. The dataset used in this study is Fire’18-MaponSMS. Thisstudy proposed an ensemble model based on AdaBoostM1 and Random Forest (AMBRF) for AP using multiplelinguistic features that are stylistic, character-based, word-based, and sentence-based. The proposed model iscontrasted with several of the well-known models fromthe literature, including J48-Decision Tree (J48),Na飗e Bays(NB), K Nearest Neighbor (KNN), and Composite Hypercube on Random Projection (CHIRP), NB-Updatable,RF, and AdaboostM1. The overall outcome shows the better performance of the proposed AdaboostM1 withRandom Forest (ABMRF) with an accuracy of 54.2857% for age prediction and 71.1429% for gender predictioncalculated on stylistic features. Regarding word-based features, age and gender were considered in 50.5714% and60%, respectively. On the other hand, KNN and CHIRP show the weakest performance using all the linguisticfeatures for age and gender prediction.

关键词： Digital forensics author profiling for security AdaBoostM1 random forest ensemble learning

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Tuning structural,electrical,dielectric and magnetic properties of Mg-Cu-Co ferrites via dysprosium(Dy^(3+))doping

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Journal of Rare Earths 2024年第1期42卷 137-146,I0005页

作者： Maria Akhtar M.S.Hasan Nasir Amin N.A.Morley Muhammad Imran arshad Department of Physics Government College UniversityFaisalabad38000Pakistan Department of Physics The University of Lahore53700Pakistan Department of Materials Science and Engineering The University of SheffieldS13JDUK Department of Physics&Astronomy University College LondonUK

In current research work,Dy3+substituted Mg0.5Cu0.25Co0.25Fe2-xDyxO4(0.0≤x≤0.04 with the step interval of 0.01)soft ferrites were synthesized by the sol-gel auto combustion *** prepared samples were characterized by the techniques using X-ray diffraction(XRD),scanning electron microscopy(SEM),energy dispersive X-ray spectroscopy(EDS),Fourier transform infrared(FTIR)spectroscopy,curre nt-voltage(Ⅰ-Ⅴ)measurement,LCR meter,vibrating sample magnetometer(VSM)and *** data reveal that the average crystallite size is 49.71 nm and the lattice constant is 0.83703 nm for sample x=*** non-uniform grain growth was demonstrated by micrographs and impurity-free elemental composition was observed from EDX *** DC resistivity has an increasing and decreasing trend in ferromagnetic and paramagnetic regions with an increase in ***,the high resistivity is observed with the order of 1010Ω·cm,and the activation energy is 0.944 eV for samples x=*** dielectric parameters including dielectric constant,dielectric losses,and impedance gradually decrease with the increase in frequency from 8 Hz to 8 *** minimum dielectric loss at high frequency is found for sample x=*** coercivity(Hc)and saturation magnetization(Ms)are found in the ranges of 520.82-544.02 Oe and 20.5841-21.1473 emu/g,*** observations confirm that dysprosium(x=0.03)doped MCC-soft ferrites may be applicable in transformer cores,microwave absorbance,and telecommunication devices.

关键词： Soft ferrites DC resistivity Dielectric loss Impedance Coercivity Rare earths

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Review on current development of polybenzimidazole membrane for lithium battery

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Journal of Energy Chemistry 2024年第4期91卷 579-608页

作者： Yonggui Deng arshad Hussain Waseem Raza Xingke Cai Dongqing Liu Jun Shen College of Mechatronics and Control Engineering Shenzhen UniversityShenzhen 518060GuangdongChina Interdisciplinary Research Center for Hydrogen Technologies and Carbon Management(IRC-HTCM) King Fahd University of Petroleum&MineralsKFUPM Box 504031261 DhahranSaudi Arabia Institute for Advanced Study Shenzhen UniversityShenzhen 518060GuangdongChina

With the rapid development of portable technology,lithium batteries have emerged as potential candidates for high-performance energy storage systems owing to their high energy density and cycling *** the key components of a lithium battery system,the separator plays a critical role as it directly influences the battery performance benchmark(cycling performance and safety).However,traditional polyolefin separators(polypropylene/polyethylene)are unable to meet the demands of highperformance and safer battery systems due to their poor electrolyte compatibility,thermal runaways,and ultimate growth of *** contrast,membranes fabricated using polybenzimidazole(PBI)exhibit excellent electrolyte wettability and outstanding thermal dimensional stability,thus holding great potential as separators for high-performance and high-safety *** this paper,we present a comprehensive review of the general requirements for separators,synthesis technology for separators,and research trends focusing PBI membranes in lithium batteries to alleviate the current commercial challenges faced by conventional polyolefin *** addition,we discuss the future development direction for PBI battery separators by considering various factors such as production cost,ecological footprint,preparation technology,and battery component *** exploring these perspectives,we aim to promote the continued application and exploration of PBI-based materials to advance lithium battery technology.

关键词： Lithium batteries Separators Porous separators Polybenzimidazole Membrane

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Ionic potency regulation of coagulation bath induced by saline solution to control over the pore structure of PBI membrane for highperformance lithium metal batteries

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Journal of Energy Chemistry 2024年第7期94卷 288-298页

作者： arshad Hussain Waseem Raza Andleeb Mehmood Sana Jalees Lihong Ao Yonggui Deng Aymeric Ramiere Xingke Cai Dongqing Liu College of Civil and Transportation Engineering Shenzhen UniversityShenzhen 518060GuangdongChina Institute for Advanced Study Shenzhen UniversityShenzhen 518060GuangdongChina Institute of Carbon Neutrality Zhejiang Wanli UniversityNingbo 315100ZhejiangChina College of Light Industry and Chemical Engineering Dalian Polytechnic UniversityDalian 116034LiaoningChina College of Physics and Optoelectronic Engineering Shenzhen UniversityShenzhen 518060GuangdongChina College of Mechatronics and Control Engineering Shenzhen UniversityShenzhen 518060GuangdongChina

In this study,we have explored the use of water as a non-solvent for tuning the microstructure of poly-benzimidazole(PBI)membranes,which are potential separators for lithium metal batteries(LMBs).The traditional method for membrane synthesis called nonsolvent-induced phase separation(NIPS),usually relies on hazardous and costly organic *** dissolving sodium chloride(Nacl)in water,we could adjust the water ionic potency and the exchange speed of the non-solvent with the DMAC solution to change the micropore structure of the PBI *** increasing Nacl concentration,the micro-pores in the PBI membrane transitioned from finger-like to sponge-like *** to com-mercial separators like the Celgard separator,the PBI membrane with sponge-like micropores exhibited better regulation of lithium deposition and improved Li^(+) transportation capability due to its good wetta-bility with the ***,the PBI membrane-based Li/Li symmetric cell and Li/LiFePO_(4) full cell demonstrated superior performance compared to the Celgard-based *** research proposes an eco-friendly and scalable synthetic approach for fabricating commercial separators for LMBs,addressing the issue of lithium dendrite growth and improving overall battery safety and performance.

关键词： Lithium metal-based battery Salt-induced Polybenzimidazole Tunablemorphology lonic potency

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