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Hospital admissions from alcohol-related acute pancreatitis during the COVID-19 pandemic:A single-centre study

World Journal of Clinical Cases 2022年第25期10卷 8837-8843页

作者： Wai Kin Mak Davide Di Mauro Eleanor Pearce Laura Karran aye myintmo Jessica Duckworth Amira Orabi Rebekah Lane Sophie Holloway Antonio Manzelli Somayyeh Mossadegh Upper GI Surgery Royal Devon and Exeter HospitalExeter EX25DWUnited Kingdom General Surgery Torbay HospitalTorquay TQ27AAUnited Kingdom General Surgery Chelsea and Westminster HospitalLondon SW109NHUnited Kingdom General Surgery Royal Cornwall Hospital TreliskeTruro TR13LJUnited Kingdom

BACKGROUND The United Kingdom government introduced lockdown restrictions for the first time on 23 March 2020 due to coronavirus disease 2019(COVID-19)*** were partially lifted on 15 June and further eased on 4 *** in social behaviour,including increased alcohol consumption were described at the ***,there were no data available to consider the impact of these changes on the number of alcohol-related disease admissions,specifically alcoholrelated acute pancreatitis(AP).This study evaluated the trend of alcohol-related AP admissions at a single centre during the initial COVID-19 *** To evaluate the trend in alcohol-related AP admissions at a single centre during the initial COVID-19 lockdown in the United *** All patients admitted with alcohol-related AP from March to September 2016 to 2020 were considered in this *** demographics,their initial presentation with AP,any recurrent admissions,disease severity and length of stay,were evaluated using ANOVA andχ^(2)and Kruskal–Wallis *** One hundred and thirty-six patients were included in the *** highest total number of AP admissions was seen in March–September 2019 and the highest single-month period was in March–May *** for first-time presentations of AP were highest in 2020 compared to other year groups and were significantly higher compared to previous years,for example,2016(P<0.05).Furthermore,the rate of admissions decreased by 38.89%between March–May 2020 and June–September 2020(P<0.05),coinciding with the easing of lockdown *** significant decrease was not observed in the previous year groups during those same time *** for recurrent AP were highest in *** median length of hospital stay did not differ between patients from each of the year *** An increased number of admissions for alcohol-related AP were observed during months when lockdown restrictions were enforced;a fall in figur

关键词： Alcohol abuse Alcohol-related acute pancreatitis COVID-19 pandemic

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Stabilization of the Cascaded ODE-Schrödinger Equations Subject to Observation With Time Delay

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IEEE/CAA Journal of Automatica Sinica 2019年第4期6卷 1027-1035页

作者： aye aye Than Junmin Wang the School of Mathematics and Statistics Beijing Institute of TechnologyBeijing 100081China IEEE

This paper focuses on the stabilization of the cascaded Schrodinger-ODE equations subject to the observation with time *** observer and predictor systems are designed to estimate the state variable on the time interval[0,t-τ]when the observation is available,and to predict the state variable on the time interval[t-τ,t]when the observation is not available,*** on the estimated state variable and the output feedback stabilizing controller using the backstepping method,it is shown that the closed-loop system is exponentially stable.

关键词： Backstepping observer and predictor ODE-Schrödinger system stability time delay

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Characteristics of gas-liquid pulsed discharge plasma reactor and dye decoloration efficiency

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Journal of Environmental Sciences 2012年第5期24卷 840-845页

作者： Nyein Nyein aye Masayuki Sato Environmental Science and Engineering College Dalian Maritime University

The pulsed high-voltage discharge is a new advanced oxidation technology for water treatment. Methyl Orange （MO） dye wastewater was chosen as the target object. Some investigations were conducted on MO decoloration including the discharge characteristics of the multi-needle reactor, parameter optimization, and the degradation mechanism. The following results were obtained. The color group of the azo dye MO was effectively decomposed by water surface plasma. The decoloration rate was promoted with the increase of treatment time, peak voltage, and pulse frequency. When the initial conductivity was 1700 μS/cm, the decoloration rate was the highest. The optimum distance between the needle electrodes and the water surface was 1 mm, the distance between the grounding electrode and the water surface was 28 mm, and the number of needle electrodes and spacing between needles were 24 and 7.5 mm, respectively. The decoloration rate of MO was affected by the gas in the reactor and varied in the order oxygen 〉 air〉 argon 〉 nitrogen, and the energy yield obtained in this investigation was 0.45 g/kWh.

关键词： multi-needle plasma reactor water surface plasma decoloration efficiency Methyl Orange decoloration

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CONSTRUCTING AN ACCESS SYSTEM FOR UNBANKED IN MYANMAR TO A MICROFINANCE INSTITUTION

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Journal of Systems Science and Systems Engineering 2015年第2期24卷 229-257页

作者： Hnin Pwint aye Yoshiteru Nakamori School of Knowledge Sciences Japan Advanced Institute of Science and Technology

In Myanmar, the formal financial institution does not provide uncollateralized credits. The rural unbanked under the poverty line is depending on the informal money-lenders with high interest rate. Private Agency Collaboration Together is only one microfinance institution providing the credits without collateral and with low interest rate to the unbanked in Myanmar. Half of the unbanked are unable to borrow the loans from the microfinance institution because of the weakness of the information contribution and the strict legal policies of the microfinance institution. Therefore, the objective of this study is to construct a system to improve the relationship between the microfinance institution and the unbanked by reducing the obstacles in the current system ofmicrofinance institution. The legal policy is studied from the vision of the local unbanked as the originality of this research and the /-System methodology is applied to accomplish the research. The current system comprises the information contribution, loans and legal policies. The current system is only one relationship between the microfinance institution and unbanked. When the ten obstacles occurred in the current system, the unbanked cannot approach to the microfinance institution. An access system including four sub-systems is developed depending on the collected ideas to solve these obstacles and intend to improve the relationship between microfinance institution and the unbanked.

关键词： Legal policy microfinance institution unbanked access system obstacles

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Exploring the genetic basis of pre-harvest sprouting in rice through a genome-wide association study-based haplotype analysis

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Journal of Integrative Agriculture 2024年第8期23卷 2525-2540页

作者： Myeong-Hyeon Min aye aye Khaing Sang-Ho Chu Bhagwat Nawade Yong-Jin Park Department of Plant Resources College of Industrial SciencesKongju National UniversityYesan 32439Republic of Korea Department of Agronomy Yezin Agricultural UniversityNay Pyi Taw 15013Myanmar

Pre-harvest sprouting(PHS)poses a significant global challenge to cereal production,impacting both yield and *** this study,we employed genome-wide association studies(GWAS)on diverse rice accessions to identify novel PHS-associated *** assessment of 127 cultivated accessions for panicle germination(PHS)and detached grain germination(germination rate of detached grains at the 14th day(D14))revealed considerable phenotypic variation among rice *** analysis identified 91 significant signals at–log10(P-value)>5,including 15SNPs for PHS and 76 SNPs for D14.A subsequent linkage disequilibrium(LD)block-based GWAS analysis detected 227 significant SNPs for both traits,consisting of 18 nonsynonymous substitutions located on the coding regions of nine *** haplotype analysis identified 32 haplotypes,with 10 specific to cultivated accessions,19 specific to the wild type,and three shared between them.A phenotypic assessment of major haplotypes revealed significant differences between resistant(Hap1 and Hap2)and susceptible haplotypes(Hap5,Hap27,and Hap28),distinguished by a G/A SNP within a novel gene,*** identified haplotypes offer promising prospects for haplotypebased breeding aimed at enhancing PHS resistance in rice.

关键词： rice PHS dormancy germination GWAS haplotype abiotic stress

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Development and validation of a transient simulation model of a full-scale PCM embedded radiant chilled ceiling

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Building Simulation 2023年第6期16卷 813-829页

作者： Seyedmostafa Mousavi Behzad Rismanchi Stefan Brey Lu aye Renewable Energy and Energy Efficiency Group Department of Infrastructure EngineeringFaculty of Engineering and Information Technology(FEIT)The University of MelbourneMelbourneVIC3010Australia InvAus Pty Ltd. MelbourneVIC3000Australia

The recent significant rise in space cooling energy demand due to the massive use of air-conditioning systems has adversely changed buildings’energy use patterns *** updated energy technology perspectives highlight the need for innovative cooling systems to address this growing cooling *** change material embedded radiant chilled ceiling(PCM-RCC)has lately acquired popularity as they offer more efficient space cooling together with further demand-side *** advancements in PCM-RCC applications have increased the necessity for reliable simulation models to assist professionals in identifying improved designs and operating *** this study,a transient simulation model of PCM-RCC has been developed and validated using measured data in a full-scale test cabin equipped with newly developed PCM ceiling *** model,developed in the TRNSYS simulation studio,includes Type 399 that uses the Crank-Nicolson algorithm coupled with the enthalpy function to solve transient heat transfer in PCM ceiling *** developed model is validated in both free-running and active operation modes,and its quality is then evaluated using several validation *** results obtained in multiple operating scenarios confirm that the model simulates the transient behaviour of the PCM-RCC system with an accuracy within±10%.Aided by this validated model,which offers the user detailed flexibilities in the system design and its associated operating schemas,PCM-RCC’s potentials regarding peak load shifting,energy savings,and enhanced thermal comfort can be investigated more reliably.

关键词： phase change material(PCM) radiant cooling ceiling panel modelling and simulation validation

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Numerical Investigation of Zigzag Bending-Angle Channel Effects on Thermal Hydraulic Performance of Printed Circuit Heat Exchanger

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Journal of Thermal Science 2024年第1期33卷 56-69页

作者： Nyein Nyein aye Withun HEMSUWAN Pichitra UANGPAIROJ Chalothorn THUMTHAE School of Mechanical Engineering Suranaree University of TechnologyNakhon Ratchasima 30000Thailand

This study investigated the effects of zigzag-flow channel bending angle in printed circuit heat exchangers(PCHEs) using a computational fluid dynamics method with ANSYS-FLUENT *** three-dimensional model of PCHE with a 15° curved,zigzag channel was conducted for preliminary *** comparisons between the CFD simulation results and the experimental data showed good agreement with some discrepancies in the heat transfer and pressure drop *** addition,different bending angle configurations(0°,3° to 30°) of zigzag channels were analyzed to obtain better thermal-hydraulic performance of the zigzag channel PCHE under different inlet mass flow *** criteria of heat transfer and frictional factor were applied to evaluate the thermal-hydraulic performance of the *** results showed that the 6° and 9°bending channel provided good thermal-hydraulic *** correlations were developed using the 6°and 9° bending channel angles in PCHE designs to predict the Nusselt number and friction factor.

关键词： printed circuit heat exchanger zigzag channel angle three-dimensional model thermal-hydraulic performance

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Current medical management of endocrine-related male infertility

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Asian Journal of Andrology 2016年第3期18卷 357-363,I0007页

作者： Joshua D Ring aye A Lwin Tobias S Kohler Division of Urology Department of Surgery Southern Illinois University Springfield IL 62794 USA.

Male factor contributes to 50%-60% of overall infertility but is solely responsible in only 20% of couples. Although most male factor infertility is ascertained from an abnormal semen analysis, other male factors can be contributory especially if the sample returns normal. Male infertility can be due to identifiable hormonal or anatomical etiologies that may be reversible or irreversible. This manuscript will highlight existing guidelines and our recommendations for hormone evaluation for male infertility and empiric therapies including multivitamins, estrogen receptor modulators （clomiphene）, estrogen conversion blockers （anastrozole）, and hormone replacement.

关键词： anastrazole clomid human chorionic gonadotropin male infertility sex hormone-binding globulin

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GREEN BUILDING RATING SYSTEM SCORES FOR BUILDING REUSE

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Journal of Green Building 2012年第2期7卷 105-112页

作者： Lu aye Dominique Hes Department of Infrastructure Engineering Melbourne School of EngineeringThe University of MelbourneAustralia School of Architecture Building and PlanningThe University of MelbourneAustralia

Green Building rating systems are the main vehicles for commercial application of ecologically sustainable design for *** less materials,modular design for deconstruction,long life structure,using recoverable materials are emerging concepts to reduce environmental impacts and increase the resource and economic efficiency of *** has been argued that because of recent emergence of these concepts,Green Building rating systems do not fairly recognise the environmental benefits *** paper quantifies the impacts of the building reuse concept on the environment and the Green Building rating system scores and compares this with the energy *** was found that lifecycle embodied greenhouse gas emission of approximately 20 kg CO_(2)-e/m^(2)/annum could be saved,if 80%of the office building components(structure,façade,wall,floor and roof)were reused in Australia.A second finding was that the current BREEAM 2008 and LEED 2009 tools do not provide fair recognition of the potential lifecycle embodied greenhouse gas emission reduction of building reuse compared to operational greenhouse gas emission reduction.

关键词： building reuse embodied greenhouse gas emission green building rating system

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Synthesis and cytotoxicity of 28-carboxymethoxy lupane *** of 28-O-acylation over 28-O-alkylation of betulm by ethyl bromoacetate

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Chinese Chemical Letters 2009年第10期20卷 1141-1144页

作者： aye aye Mar Ali Koohang Nathan D.Majewski Erika L.Szotek David A.Eiznhamer Michael T.Flavin Advanced Life Sciences Inc.1440 Davey RoadWoodridgeIL 60517 USA

28-Carboxymethoxy lupane tritepenoids 3 and 4 were synthesized by alkylation of betulin with the THP protected 2- hydroxyethyl iodide followed by oxidation and reduction. Direct reaction of betulin （5） or betulone （10） with ethyl bromoacetate led to 28-O-acylation, instead of 28-O-alkylation. The targeted compounds 3 and 4 were not cytotoxic at the highest concentration tested （75 μmol/L）, suggesting that elongation of the chain length at the 28-position in both betulinic acid （1） and betulonic acid （2） was detrimental to the cytotoxicity. The acylation products 28-O-bromoacetates （Sa, 8b and 11） and 28-O-methoxyacetate 13 exhibited cytotoxicity against several cancer cell lines tested.

关键词： Betulinic acid Betulin Betulonic acid 28-O-Alkylation 28-O-Acylation Cytotoxicity

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