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The Relationship between Human Papillomavirus and Oesophageal Squamous Cell Carcinoma in China—A Review of the Evidence

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Advances in Infectious Diseases 2013年第1期3卷 17-34页

作者： Surabhi S. Liyanage Qian Li Yang Zheng Holly Seale Philip J. Crowe Anthony T. Newall Bayzidur Rahman Eva Segelov Chenxu Qu Fanghui Zhao Junfeng Liu Zhanhai Gao Weixian Shi Peng Yang aye moa Chandini Raina MacIntyre Centre for Disease Control and Prevention Beijing China Department of Cancer Epidemiology Cancer Institute Chinese Academy of Medical Sciences Peking Union Medical College Beijing China Department of Medicine St. Vincent’s Hospital Clinical School The University of New South Wales Sydney Australia Department of Surgery Fourth Hospital Shijiazhuang China Department of Surgery Prince of Wales Hospital Clinical School The University of New South Wales Sydney Australia School of Public Health and Community Medicine The University of New South Wales Medicine The University of New South Wales Sydney Australia

Background: China has one of the highest incidence rates of oesophageal cancer in the world. The role of human papillomavirus (HPV) has been extensively researched in oesophageal squamous cell carcinoma (OSCC) with indeterminate results. The majority of these studies have been conducted in the Chinese population. Evidence for a definitive HPV-OSCC association could potentially support prophylactic vaccination in target populations, highlighting the need for ongoing investigation. The aim of this review is to summarise the findings of HPV DNA in OSCC tissue in Chinese subjects, with a view to informing further research in this area. Methods: A systematic literature search of the Chinese National Knowledge Infrastructure (CNKI) database, Medline, Embase and PubMed was conducted for all studies in English and Chinese language, examining OSCC tissue for HPV DNA in China. Reference lists of retrieved articles were reviewed and hand searches of relevant, key journals were conducted, to source articles which were not electronically indexed. Sixty-four studies met our selection criteria. Data from case-control and cross-sectional studies were analysed separately for any HPV-OSCC association, using the Epi InfoTM 3.5.3 software program. Results: From all studies conducted in the Chinese population, 2166/5953 (36%) of all OSCC tissue and 478/1684 (28%) of healthy control tissue, tested positive for HPV. We found that 11/16 case-control and cross-sectional studies had a statistically significant crude odds ratio, which supported a potential HPV-OSCC association. The largest study, carried out in the high incidence County of Anyang in Henan Province, reported 207/265 (78%) OSCC tissues testing positive for HPV DNA against 203/357 (57%) controls and had an unadjusted odds ratio of 2.71 (p-value Conclusion: A rigorous meta-analysis would improve interpretation of the data and a well-designed large-scale case-control study is warranted. If a link is found between HPV and OSCC, pro

关键词： Human Papillomavirus Oesophageal Carcinoma Squamous Cell Carcinoma HPV Vaccine China

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Youth Participation at the Third UN World Conference on Disaster Risk Reduction

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International Journal of Disaster Risk Science 2015年第2期6卷 150-163页

作者： Lydia Cumiskey Tam Hoang Sachi Suzuki Claire Pettigrew moa M.Herrgard Disaster Risk Reduction Working Group UN Major Group for Children&Youth Youth Beyond Disasters Water Youth Network Marine and Coastal Systems Health and Safety Emergency Management and Business Continuity UnitVictoria University Standing Committee on Human Right and Peace International Federation of Medical Students’Associations Department of Engineering Tohoku University

This article summarizes and analyzes the Children & Youth Forum and youth participation in the process during and leading up to the Third UN World Conference on Disaster Risk Reduction(WCDRR) in2015. An organizing committee consisting of international students and young professionals brought together around200 young professionals and students from around the globe to exchange ideas and knowledge on reducing disaster risk, building resilient communities, and advocating for the inclusion of youth priorities within the Sendai Framework for Disaster Risk Reduction 2015–2030(SFDRR). The knowledge exchange during the Forum was structured around a Toolbox for Resilience that connected to the SFDRR section on Priorities for Action. This article presents the outcomes of these young people’s participation in the disaster risk reduction capacity building eventsand policy-making, as well as the follow-up actions envisioned by the young participants of the Forum. The voices of the younger generation were heard in the SFDRR and young people are ready to expand their actions for the framework’s effective implementation. Young people call on technical experts, donors, NGOs, agencies, governments, and academia to partner with them on this journey to create a more resilient tomorrow together.

关键词： Children & Youth Forum Disaster risk reduction SFDRR Toolbox for Resilience

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具有原子运动的双光子J-C模型中量子力学通道与量子互熵

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物理学报 2005年第2期54卷 703-709页

作者：刘小娟方卯发周清平湖南师范大学物理与信息学院中国科学院安徽光学精密机械研究所合肥230031 湖南科技大学物理学院湘潭411201

用量子信息理论研究具有原子运动的双光子Jaynes_Cumming模型动力学 .给出了该模型中表示原子态变化的量子力学通道 ,导出了量子互熵和原子约化熵 ,考察了原子运动及场模结构对量子互熵的影响 ,以及原子量子力学通道“开启”与“关闭”... 详细信息

用量子信息理论研究具有原子运动的双光子Jaynes_Cumming模型动力学 .给出了该模型中表示原子态变化的量子力学通道 ,导出了量子互熵和原子约化熵 ,考察了原子运动及场模结构对量子互熵的影响 ,以及原子量子力学通道“开启”与“关闭”状态和原子与场纠缠程度的关系 .结果表明量子力学通道特性强烈依赖于原子运动、场模结构以及原子与场的纠缠 .

关键词：原子运动量子力学双光子 J-C模型纠缠量子信息理论 Jaynes-Cumming模型依赖影响通道

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Ultrasound-assisted extraction of bound phenolic compounds from the residue of Apocynum venetum tea and their antioxidant activities

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Food Bioscience 2022年第3期47卷 502-511页

作者： Shengwei Sun Yiwen Zhao Luyao Wang Yuzhi Tan Yaning Shi Rita-Cindy aye-Ayire Sedjoah Yuting Shao Longxiang Li Mengxi Wang Jiashuai Wan Xia Fan Rong Guo Zhihong Xin Key Laboratory of Food Processing and Quality Control College of Food Science and TechnologyNanjing Agricultural UniversityNanjing210095China

Bound phenolic compounds from the residue of Apocynum venetum(***)tea were released by alkaline digestion with sonication,followed by extraction using ethyl acetate(EtOAc).The fragment ions of compounds in free and bound forms were identified by liquid chromatography electrospray ionization tandem mass spectrometry(LC-ESI-MS/MS)in both positive and negative *** investigation of chemical constituents in the EtOAc extract led to the isolation of eleven individual compounds,and their chemical structures were identified as(−)-epicatechin(1),(−)-loliolide(2),(−)-syringaresinol-4-O-β-D-glucopyranoside(3),alloside of benzyl alcohol(4),3-[(6-O-hexopyranosylhexopyranosyl)oxy]-2-(palmitoyloxy)propyl(9Z,12Z,15Z)-9,12,15-octadecatrienoate(5),apocynoside I(6),quercetin-3-O-β-D-glucopyranoside(7),kaempferol-3-O-β-D-glucopyranoside(8),[1-acetyloxy-3-[3,4,5-trihydroxy-6-[[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxypropan-2-yl]hexadecanoate(9),1-stearoyl-2-palmitoyl-sn-glycerol(10),and 3-hexene-l-O-β-D-glucoside(11)using a series of spectroscopic *** 2–5 and 9–11 were isolated for the first time from ***,while antioxidant experiments showed that compounds 1,7,and 8 displayed strong DPPH and ABTS+radical scavenging *** study represents the first investigation of bound phenolic compounds with potential health benefits in the residue of *** tea.

关键词： Apocynum venetum.L tea residue Ultrasound-assisted extraction Bound phenolic compounds Structural characterization Antioxidant activity

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红山馆

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景观设计 2018年第6期 76-83页

作者： moa Architects formzero 林涛(翻译) 不详

该项目远离附近的热带小城,藏身于橡胶保护林之中。人们在进入红山馆前,会在树林里逛逛,仿佛踏上了森林寻宝的旅程。该项目的设计以提供最好的使用体验为宗旨,折叠式天花板和墙壁扩大了室内的活动空间,能够满足不同空间的功能需求。

关键词：活动空间功能需求天花板折叠式墙壁

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Source-sink Characteristics and the Translocation of Assi- milates in New Plant Type and Intersubspecific Hybrid Rice

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Agricultural Sciences in China 2002年第2期1卷 155-162页

作者： YANG Jian-chang, ZHANG Wen-hu, WANG Zhi-qin, LIU Li-jun and ZHU Qing-sen( Key Laboratory of Crop Cultivation and Physiology, moa , Yangzhou University, Yangzhou 225009) Key Laboratory of Crop Cultivation and Physiology MOA Yangzhou University Yangzhou 225009

Both new plant type (NPT) and intersubspecific hybrid rice (IHR) had large sink size (total number of spikelets per m2), however, poor grain filling limited their potential in the grain yield. Compared to the three-line indica hybrid of Shanyou 63 (CK), NPT and IHR showed higher photosynthetic potential, higher dry matter accumulation and higher ratio of dry weight to spikelets (total dry wt./total number of spikelets) from heading to harvest. But both exhibited a low export percentage and transfer ratio of assimilates, low partitioning of 14C to grains from labeled flag leaves, low harvest indices and low physiological activities (IAA content and activities of ATPase and starch synthase) of grains at early grain-filling stage. The physiological activities of grains at early filling stage were significantly correlated with the export percentage and transfer ratio of assimilates, ripened-grain percentage and grain plumpness (r = 0.85 - 0.95). The source-sink ratio (dry matter wt./spikelet and nonstructural carbohydrate/spikelet) at heading was positively correlated with physiological activities of grains (r = 0. 84 - 0. 97 ). It is suggested that low physiological activities of grains at early filling stage is attributed to low source-sink ratio at heading, and the low sink activity weakens the ability to remobilize assimilates into grains, and leads to poor grain filling in NPT and IHR.

关键词： Rice New plant type Intersubspecifiic hybrid Source-sink Assimilate translocation

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Genomic and genic sequence variation in synthetic hexaploid wheat (AABBDD) as compared to their parental species

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Progress in Natural Science:Materials International 2008年第5期18卷 533-538页

作者： Lihong Nie, Zongfu Han, Lahu Lu, Yingyin Yao, Qixin Sun, Zhongfu Ni Key Laboratory of Crop Heterosis and Utilization (MOE) and State Key Laboratory for Agrobiotechnology, Key Laboratory of Crop Genomics and Genetic Improvement (moa), Beijing Key Laboratory of Crop Genetic Improvement, Department of Plant Genetics & Breeding, China Agricultural University, Beijing 100094, China Key Laboratory of Crop Heterosis and Utilization (MOE) and State Key Laboratory for Agrobiotechnology Key Laboratory of Crop Genomics and Genetic Improvement (MOA) Beijing Key Laboratory of Crop Genetic Improvement Department of Plant Genetics & Breeding China Agricultural University Beijing 100094 China

In order to understand the genomic changes during the evolution of hexaploid wheat, two sets of synthetic hexaploid wheat from hybridization between maternal tetraploid wheat (AABB) and paternal diploid goat grass (DD) were used for DNA-AFLP and single strand conformation polymorphism (SSCP) analysis to determine the genomic and genic variation in the synthetic hexaploid wheat. Results indicated that more DNA sequences from paternal diploid species were eliminated in the synthetic hexaploid wheat than from maternal tetraploid wheat, suggesting that genome from parental species of lower ploidity tends to be eliminated preferentially. However, sequence variation detected by SSCP procedure was much lower than those detected by DNA-AFLP, which indicated that much less variation in the genic regions occurred in the synthetic hexaploid wheat, and sequence variations detected by DNA-AFLP could be derived mostly from non-coding regions and repetitive sequences. Our results also indicated that sequence variation in 4 genes can be detected in hybrid F1, which suggested that this type of sequence variation could be resulted from distant hybridization. It was interesting to note that 3 out of the 4 genes were mapped and clustered on the long arm of chromosome 2D, which indicated that variation in genic sequences in synthetic hexaploid wheat might not be a randomized process.

关键词： Synthetic hexaploid wheat Polyploidy Genome Sequence variation

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Genetic diversity in Chinese modern wheat varieties revealed by microsatellite markers

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Science China(Life Sciences) 2006年第3期49卷 218-226页

作者： HAO Chenyang, WANG Lanfen, ZHANG Xueyong, YOU Guangxia, DONG Yushen, JIA Jizeng, LIU Xu, SHANG Xunwu, LIU Sancai & CAO Yongsheng Key Laboratory of Crop Germplasm & Biotechnology, moa, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing 100081, China Agronomy College, Gansu Agricultural University, Lanzhou 730070, China 1. Key Laboratory of Crop Germplasm & Biotechnology MOA Institute of Crop Sciences Chinese Academy of Agricultural Sciences Beijing 100081 China 2. Agronomy College Gansu Agricultural University Lanzhou 730070 China

Genetic diversity of 1680 modern varieties in Chinese candidate corecollections was analyzed at 78 SSR loci by fluorescence detection system. A total of 1336 alleleswere detected, of which 1253 alleles could be annotated into 71 loci. For these 71 loci, the allelesranged from 4 to 44 with an average of 17.6, and the PIC values changed from 0.19 to 0.89 with anaverage of 0.69. (1) In the three genomes of wheat, the average genetic richness was B>A>D, and thegenetic diversity indexes were B>D>A. (2) Among the seven homoeologous groups, the average geneticrichness was 2=7>3>4>6>5>1, and the genetic diversity indexes were 7>3>2>4>6>5>1. As a whole, group7 possessed the highest genetic diversity, while groups 1 and 5 were the lowest. (3) In the 21wheatchromosomes, 7A, 3B and 2D possessed much higher genetic diversity, while 2A, 1B, 4D, 5D and 1D werethe lowest. (4) The highest average genetic diversity index existed in varieties bred in the 1950s,and then it declined continually. However, thechange tendency of genetic diversity among decadeswas not greatly sharp. This was further illustrated by changes of the average genetic distancebetween varieties. In the 1950s it was the largest (0.731). Since the 1960s, it has decreasedgradually (0.711, 0.706, 0.696, 0.695). The genetic base of modern varieties is becoming narrowerand narrower. This should be given enough attention by breeders and policy makers.

关键词： wheat, microsatellite markers, genetic diversity.

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