检索结果-南通市图书馆

Cyanocobalamin and 25-Hydroxy Vitamin D Levels in Gout Patients: An Overlooked Issue

Open Journal of Rheumatology and Autoimmune Diseases 2016年第4期6卷 96-101页

作者： Yunus Emre Yandı ercan Gencer Beyza Kılavuz Ali Erdem Baki Hatice Şahin Muammer Bilici Metin Işık Tamer Alışkan Division of Biochemistry Department of Medical Services and Techniques Health Sciences Vocational School Bülent Ecevit University Zonguldak Turkey Department of Physiology Faculty of Medicine Bülent Ecevit University Zonguldak Turkey Department of Internal Medicine Faculty of Medicine Bülent Ecevit University Zonguldak Turkey Department of Physical Medicine and Rehabilitation Faculty of Medicine Bülent Ecevit University Zonguldak Turkey Division of Rheumatology Department of Internal Medicine Faculty of Medicine Bülent Ecevit University Zonguldak Turkey Department of Urology Faculty of Medicine Bülent Ecevit University Zonguldak Turkey

Gout is one of the most frequent type of inflammatory arthritis in developed countries. The elevation of serum uric acid levels and the deposition of monosodium urate crystals in joints and/or soft tissues are the mechanisms of pathogenesis. Uric acid is a product of the metabolic cleavage of purine nucleotides and organ meats, beef, pork, and lamb, anchovies, sardines, herring, mackerel, scallops, gravy and beer are known to be very rich in purine. On the other hand, some of these foods are also the main sources of vitamin B12 (cyanocobalamin). As a chronic inflammatory arthritis corticosteroids are frequently prescribed for gout patients, meaning a higher risk for osteoporosis which may be blocked by daily calcium and vitamin D replacement. However, there are no recommendations about screening or replacement of Gout patients for vitamin D and B12. Herein, we evaluated our patients retrospectively to document their vitamin levels and also to find the factors associated with vitamin deficiency. Totally, 90 patients, 71 (79.9%) male and 19 (20.1%) female patients with a median diagnostic age of 55 (19 - 80) were included. Thirty six (40%) patients were newly diagnosed (group 1) but 54 (60%) patients had established diseases (group-2) with median disease duration of 36 (11-240) months. Nearly half (47.2%) of the patients in group-1 and 37% of the patients in group-2 had vitamin B 12 deficiency. Similarly, 38.9% in each group had vitamin D deficiency and 52.8% in group-1 and 44.4% in group-2 had vitamin D insufficiency. In conclusion, we strongly recommend routine screening and replacement of vitamin B12 and D for patients with Gout.

关键词： Gout Vitamin B12 Vitamin D

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Integrated Assessment of Cardiac PET/MRI: Co-Registered PET and MRI Polar Plots by Mutual MR-Based Segmentation of the Left Ventricular Myocardium

引用

World Journal of Cardiovascular Diseases 2017年第4期7卷 91-104页

作者： Felix Nensa Thorsten D. Poeppel ercan Tezgah Philipp Heusch Kai Nassenstein Michael Forsting Andreas Bockisch Raimund Erbel Thomas Schlosser Department of Diagnostic and Interventional Radiology and Neuroradiology University Hospital Essen University of Duisburg-Essen Essen Germany Clinic for Nuclear Medicine University Hospital Essen University of Duisburg-Essen Essen Germany Clinic for Cardiology University Hospital Essen University of Duisburg-Essen Essen Germany Department of Diagnostic and Interventional Radiology University Hospital Dusseldorf University of Dusseldorf Dussel-dorf Germany

Background: In the present study, we sought to describe a procedure for the creation of co-registered positron emission tomography (PET) and magnetic resonance imaging (MRI) polar plots of cardiac PET/MRI examinations, validate the resulting plots against available standard methods in patients with myocardial infarction and provide examples that demonstrate the advantage of the novel approach over existing standards. Methods: Co-registered LGE and PET short-axis images were transformed into polar maps based on a radial sampling pattern. LGE was automatically detected using an automated thresholding algorithm (ATA). In 20 PET/MRI examinations in patients with acute myocardial infarction, agreement between manual LGE assessment and the ATA classification was calculated. Also agreement between MRI-segmentation based PET polar plots and standard PET polar plots (created with the Corridor4DM software package) was assessed. Results: No statistically significant difference in infarct sizes between manual and ATA segmentation was found (p = 0.12). Both methods were highly correlated (Pearson’s r = 0.96, p Conclusion: A straightforward software approach for the creation of co-registered PET and MRI polar plots was described and successfully demonstrated in PET/MRI studies of myocardial infarction and inflammation.

关键词： Cardiac PET/MRI Bull’s Eye Polar Plot Polar Map

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Inhibition of Biofilms by Non-Thermal Plasma Treated Novel Solutions

引用

Advances in Microbiology 2014年第16期4卷 1188-1196页

作者： Utku K. ercan Siddharth S. Joshi Adam Yost Natalie Gogotsi Sean O’Toole Michelle Paff Eric Melchior Suresh G. Joshi Department of Surgery Drexel University College of Medicine Philadelphia Pennsylvania USA Department of Microbiology and Immunology Drexel University College of Medicine Philadelphia Pennsylvania USA

Biofilms act as a reservoir of infection, and periodically release cells in vicinity that are capable of developing new biofilm colonies and disseminate infection. Many chronic bacterial infections are serious that are associated with biofilms and have high morbidity and mortality, partly due to their higher resistance to antimicrobial agents, and partly due to lack of strong biocides which can efficiently treat and inhibit biofilm formation. We recently demonstrated that nonequilibrium non-thermal dielectric-barrier discharge plasma (Plasma) can also be applied to control pathogens via applying treated-liquids, and these liquids acquire broad-spectrum antimicrobial properties. In present studies we demonstrated a range of plasma-activated simple chemical solutions which significantly inhibited biofilm formation by multidrug-resistant bacterial pathogens. Plasma-activated methionine solution exhibited strong inhibitory activity against the biofilms of car-bapenem-resistant Acinetobacter baumannii, methicillin-resistant Staphylococcus aureus, metal-lo-β-lactamase (NDM1)-positive Klebsiella pneumoniae, and Enterococcus faecalis, and prevented the formation of biofilms by about 70% as compared to untreated controls in single exposure. In addition to inhibition of biofilm formation, a complete inactivation of biofilm-embedded bacterial cells was observed in less than 30 minute’s exposure to candidate plasma-activated methionine solution. These findings suggest that plasma-activated solutions have a potential to prevent biofilm formation, and as biofilm inhibitor.

关键词： Acinetobacter baumannii Antibacterial Solution Antibiofilm Agent Biofilm MRSA Nonthermal Plasma

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

土耳其总统埃尔多安的反政变法宝

引用

商业周刊（中文版） 2016年第18期 16-18页

作者： Donna Abu-Nasr Onur Ant ercan Ersoy 永年

这位土耳其领导人对伊斯坦布尔宗教界和政界的影响得到了进一步巩固，

关键词：土耳其埃尔多安变法总统伊斯坦布尔宗教界领导人

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Cerebral magnetic resonance imaging in quiescent Crohn's disease patients with fatigue

引用

World Journal of Gastroenterology 2017年第6期23卷 1018-1029页

作者： Sanne van Erp Ece ercan Perla Breedveld Lianne Brakenhoff Eidrees Ghariq Sophie Schmid Matthias van Osch Mark van Buchem Bart Emmer Jeroen van der Grond Ron Wolterbeek Daniel Hommes Herma Fidder Nic van der Wee Tom Huizinga Désirée van der Heijde Huub Middelkoop Itamar Ronen Andrea van der Meulen-de Jong Department of Gastroenterology and Hepatology Leiden University Medical Center C.J.Gorter Center Leiden University Medical Center Department of Radiology Leiden University Medical Center Department of Medical Statistics Leiden University Medical Center Center for Inflammatory Bowel Diseases University of California Los Angeles Department of Gastroenterology and Hepatology University Medical Center Utrecht Department of Psychiatry Leiden University Medical Center Department of Rheumatology Leiden University Medical Center Department of Neuropsychology Leiden University Medical Center Department of Radiology Leiden University Medical CenterLeiden

To evaluate brain involvement in quiescent Crohn’s disease (CD) patients with fatigue using quantitative magnetic resonance imaging (MRI).METHODSMultiple MRI techniques were used to assess cerebral changes in 20 quiescent CD patients with fatigue (defined with at least 6 points out of an 11-point numeric rating scale compared with 17 healthy age and gender matched controls without fatigue. Furthermore, mental status was assessed by cognitive functioning, based on the neuropsychological inventory including the different domains global cognitive functioning, memory and executive functioning and in addition mood and quality of life scores. Cognitive functioning and mood status were correlated with MRI findings in the both study *** glutamate + glutamine (Glx = Glu + Gln) concentrations (P = 0.02) and ratios to total creatine (P = 0.02) were found in CD patients compared with controls. Significant increased Cerebral Blood Flow (P = 0.05) was found in CD patients (53.08 ± 6.14 mL/100 g/min) compared with controls (47.60 ± 8.62 mL/100 g/min). CD patients encountered significantly more depressive symptoms (P 1-weighted analysis. In addition, no correlation was found between mental status and MRI *** work shows evidence for perfusion, neurochemical and mental differences in the brain of CD patients with fatigue compared with healthy controls.

关键词： Magnetic resonance imaging Systemic inflammation Fatigue Crohn’s disease Cognition

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

氧化应激酶在开角型青光眼患者中的作用

引用

世界核心医学期刊文摘（眼科学分册） 2005年第9期1卷 36-37页

作者： Yildirim o. Ates? N.A. ercan B. 张少娟 Mersin universitesi Tip Fakültesi Hastanesi Zeytinlibahc?e Cad. 33079 Mersin Turkey

Purpose: To investigate the role of oxidative stress and lipid peroxidation in the pathogenesis of primary open-angle glaucoma (POAG). Materials and methods: The activities of myeloperoxidase (MPO), catalase (CAT), and the levels of plasma malondialdehyde (MDA) were measured in 40 (15 men and 25 women) patients with POAG and 60 (30 men and 30 women)-healthy controls. Results: Therewas no significant difference in the activities of CAT andMPO between the POAG patients and the controls. However, the plasmaMDA level was significantly higher in patients than the controls. Conclusion: The results of this preliminary study suggest that the possible alterations of plasmaMDA levels may be associated with the pathogenesis of POAG, but further research is needed to understand the role of oxidative damage in this important disorder of aging.

关键词：开角型青光眼氧化应激脂质过氧化反应过氧化氢酶血浆丙二醛髓过氧化物酶致病过程增龄性

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Synapsin Polymorphisms Could Be Correlated with Stroop Simple Reaction Time Scores

引用

American Journal of Molecular Biology 2016年第1期6卷 25-32页

作者： Ahmet Buber Burge Kabukcu Basay Omer Basay Onder Ozturk Huseyin Alacam Kemal Utku Yazici Ali Bacanli Mustafa Ertan Ay Mehmet Emin Erdal Hasan Herken Eyup Sabri ercan Child and Adolescent Psychiatry Department Pamukkale University Medical Faculty Denizli Turkey Psychiatry Department Pamukkale University Medical Faculty Denizli Turkey Child and Adolescent Psychiatry Department Firat University Medical Faculty Elazig Turkey Child and Adolescent Psychiatry Department Gaziantep Children Hospital Gaziantep Turkey Medical Biology and Genetics Department Mersin University Medical Faculty Mersin Turkey Child and Adolescent Psychiatry Department Ege University Medical Faculty Izmir Turkey

Objective: The aim of this study was to research the relationship between Attention Deficit Hyperactivity Disorder (ADHD) and the synapsin III -196G>A and -631C>G polymorphisms and study their impact on neurocognition and behavior in Turkish children and adolescents. Methods: A total of 201 ADHD-diagnosed children and 100 control subjects aged between 8 and 15 years were recruited, and genetic material was obtained from saliva. In the diagnostic assessments, the KSADS- PL semi-structured interview was applied. Children with any comorbid psychiatric diagnosis (with the exclusion of oppositional defiant disorder (ODD)), medical conditions, prior psychotropic drug use history or IQ score below 80 were excluded. For the behavioral and ADHD symptom assessments, the Turgay DSM-IV Disruptive Behaviors Rating Scale, Teacher Report Form (TRF) and Child Behavior Checklist (CBCL) were completed by the parents and teachers. Neurocognitive profiles were evaluated with the CNS-Vital Signs computerized neurocognitive test battery. Results: No significant difference in ADHD prevalence was observed between subjects with the synapsin III gene -196G>A polymorphism and -631C>G polymorphisms. These polymorphisms were also not associated with subtypes of ADHD. We found a relationship between both polymorphisms and Stroop simple reaction time. Conclusion: Synapsin’s effect could be limited during childhood, but synapsin polymorphisms could be associated with Stroop simple reaction time.

关键词： Attention Deficit Hyperactivity Disorder Synapsin III Association Cognitive Function

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

大学语文教学中优秀传统文化教育的创新研究

引用

科教文汇 2020年第25期 63-64页

作者：郭二灿郑州工业应用技术学院河南郑州451150

语文是学生从小学到大学都需要学习的一门学科。学生最开始接触语文这一学科时,主要学习一些简单的字、词、拼音等,了解不同词句的具体意思。而到了大学语文阶段,学生需要接触更多具有难度的内容。在传统的大学语文教学阶段,教师在开展... 详细信息

语文是学生从小学到大学都需要学习的一门学科。学生最开始接触语文这一学科时,主要学习一些简单的字、词、拼音等,了解不同词句的具体意思。而到了大学语文阶段,学生需要接触更多具有难度的内容。在传统的大学语文教学阶段,教师在开展语文教学时采用的方式相对陈旧。因此,在新时代背景下,当前的大学语文教师必须不断地开拓创新,所以我们就以大学语文教学中的传统文化教育作为研究方向,来看看如何针对这一内容展开创新。

关键词：大学语文传统文化教育创新

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Quality in Independent Auditing:A Research on Auditors

引用

Journal of Modern Accounting and Auditing 2020年第12期16卷 534-541页

作者： Burcu Dogan Cuma ercan Adıyaman University AdıyamanTurkey Gaziantep University GaziantepTurkey

The aim of this study is to determine the opinion related to the audit quality of independent auditors in *** this purpose,a study was carried out on the auditors operating in the TRC 1 region and having an auditor *** method was used in the *** the evaluation of the data,frequency,mean,and standard deviation were used as descriptive statistical *** addition,t-test and one-way ANOVA test were used to compare the data between independent *** results show no significant difference between the opinions of the independent auditors according to various variables.

关键词： independent audit audit quality auditor

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

信息安全环境的构建与保护

引用

河南图书馆学刊 2006年第3期26卷 28-31页

作者：刘二灿河南财经学院图书馆河南郑州450002

在这个科技大革命的时代里,黑客、噪音、污染、垃圾、入侵等虽然改头换面了,却一样没少,从经济的角度思维,它们占用了人们的有效经济运行时间,大大影响了人们的工作效率,构成了物质和精神的双重污染。促进信息化健康发展,构建安全的信... 详细信息

在这个科技大革命的时代里,黑客、噪音、污染、垃圾、入侵等虽然改头换面了,却一样没少,从经济的角度思维,它们占用了人们的有效经济运行时间,大大影响了人们的工作效率,构成了物质和精神的双重污染。促进信息化健康发展,构建安全的信息环境,30%依靠安全技术,而70%依赖于切实有效的安全管理。

关键词：信息安全环境保护管理

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：