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Advances in Nanoparticles 2020年第2期9卷 41-48页

作者： Marvit Osman Widdatallah Alaa Abdulmoneim Mohamed ayat ahmed alrasheid Hiba Abbas Widatallah Layla Fathi Yassin Sahar Hussein Eltilib Shimaa Abdel Rahman ahmed Department of Pharmacology Faculty of Pharmacy University of Medical Sciences and Technology Khartoum Sudan Department of Clinical Pharmacy Faculty of Pharmacy University of Medical Sciences and Technology Khartoum Sudan Department of Pharmacognosy Faculty of Pharmacy University of Medical Sciences and Technology Khartoum Sudan Department of Pharmaceutical Chemistry Faculty of Pharmacy University of Medical Sciences and Technology Khartoum Sudan

Synthesis of silver nanoparticles using seeds of Nigella sativa as a capping agent was evaluated in this study. Different concentrations of the aqueous extract of N. sativa with silver nitrate solution were exposed to sunlight;as a force for acceleration of the formulation. Then the silver nanoparticles were characterized by UV-Vis, scanning electron microscope (SEM) and X-ray diffraction (XRD) techniques. Antibacterial activity of the nanoparticles was investigated against Staphylococcus aureus and Escherichia coli by the disc diffusion method. The characterization of nanoparticles was detected by the change in color to yellow-brown which indicated the formulation of silver nanoparticles. Irregular shapes within range of nanoscale were detected using SEM and XRD techniques. The finding suggests that silver nanoparticles may be effectively used as antibacterial agent.

关键词： Silver Nanoparticles Nigella sativa UV-Vis SEM XRD Antibacterial Activity

Nurses’ Knowledge and Attitude Regarding Evidence-Based Practice: An Integrative Review

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Open Journal of Nursing 2022年第2期12卷 103-112页

作者： ayat Mohamed ahmed Zammar General Directorate of Health Affairs in Riyadh Region Riyadh Saudi Arabia

Background: As a result of its influence on nurses’ knowledge and practice, evidence-based practice (EBP) has gained prominence in the nursing profession. Therefore, evidence-based practice (EBP) is increasingly acknowledged as a critical component of improving the quality of healthcare and nursing care services, as well as achieving patient care excellence. Aim: One of the primary objectives of this review is to consolidate the existing research on nurses’ understanding of evidence-based practice, attitudes toward it, and practices related to it. Methods: The following databases from 2012 to 2021 have been searched such as: Cochrane Collaboration, MEDLINE, AVOID, CINAHL, EMBASE, Science Direct, ASSIA, Web of Science, Scopus, PubMed and JSTOR. Only cohort, case-control and randomized controlled trials studies with full text in English were eligible. Results: Only eight articles were found to meet the inclusion criteria out of 2155 total articles after the exclusion criteria were applied. The majority of these eight researches discovered a favourable attitude about EBP as well as a low level of expertise. Conclusion: The majority of nurses have a good attitude toward their job, but most are uninformed of the significance of EBP in their profession. In order to recognize and compare the components that may impact knowledge, attitude, and practices of EBP throughout the world in order to discover similarities that may assist global strategies for the transfer of research results to nursing, additional research on this topic is required to recognize and compare the components that may impact knowledge, attitude, and practices of EBP throughout the world in order to discover similarities that may assist global strategies for the transfer of research results to nursing.

关键词： Knowledge Attitude Evidence-Based Practice

Human leukocyte antigen class-Ⅱ DRB1 alleles and Giardia lamblia infection in children: A case-control study

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Asian Pacific Journal of Tropical Medicine 2020年第2期13卷 56-61页

作者： Samar N.El-Beshbishi ayat A.ElBlihy Raefa A.Atia ahmed Megahed Fatma A.Auf Department of Medical Parasitology Faculty of MedicineMansoura UniversityMansoura 35516Egypt Pediatric Gastroenterology and Hepatology Unit Mansoura University Children's HospitalFaculty of MedicineMansoura UniversityMansoura 35516Egypt Department of Clinical Pathology Faculty of MedicineMansoura UniversityMansoura 35516Egypt

Objective:To compare the genotype frequencies of HLA class-ⅡDRB1 alleles in Giardia(G.)lamblia-infected ***:A total of 490 Egyptian children aged 2-16 years were subjected to microscopic stool examination to detect *** infection,and to exclude other intestinal *** the basis of their microscopic findings,a group of 80 children were chosen as giardiasis cases,another 80 children were confirmed as Giardia free control group by immunochromatographic test,and the remaining children were *** giardiasis and control groups were then subjected to blood examination to identify their genetic type of HLA-DRB1 ***:HLA class-ⅡDRB1*03:01 and DRB1*13:01 alleles were significantly associated with *** infection(P<0.001 for each variable).On the other hand,HLA class-ⅡDRB1*04:02,DRB1*10:01,DRB1*14:01 and DRB1*15:01 alleles were significantly demonstrated in Giardia free ***,other HLA-DRB1 alleles did not show any significant association with ***:HLA class-ⅡDRB1*03,DRB1*13,DRB1*04,DRB1*10,DRB1*14 and DRB1*15 alleles may be involved in the establishment of host immune response to *** infection.

关键词： Giardia lamblia Giardiasis Human leukocyte antigen HLA class-ⅡDRB1 alleles Children

Protective effects of Balanites aegyptiaca extract, melatonin and ursodeoxycholic acid against hepatotoxicity induced by methotrexate in male rats

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Asian Pacific Journal of Tropical Medicine 2017年第6期10卷 627-634页

作者： ayat OS Montasser Hanan Saleh Omar A.ahmed-Farid Aida Saad Mohamed-Assem S.Marie National Organization for Drug Control And Research Faculty of Science Department of Zoology Cairo University

Objective: To compare the degree of ameliorative effects of Melatonin(MEL), Ursodeoxycholic acid(UDCA) and Balanites aegyptiaca(BA) against hepatotoxicity induced by MTX for one month. Methods: Eighty adult male rats(Sprague Dawely) weighing(190±10g), were randomly divided into eight equal groups: Control, MTX, MEL, BA, UDCA, MTX+MEL, MTX+BA, MTX+UDCA. Liver function biomarker enzymes, liver tissue oxidative stress parameters, together with total antioxidant capacity and tumor necrosis factor(TNF-α) were determined. Histopathological and immunohistochemistry examinations for TNF-α were also done. Results: MTX showed significant increase in alanine transaminase(ALT), aspartate transaminase(AST), alkaline phosphatase(ALP), gamma glutamyl transferase(GGT), total and direct bilirubin, as well as TNF-α levels, oxidized glutathione(GSSG), malodialdehyde(MDA) and nitric oxide(NO). whereas, total protein, albumin, total antioxidant capacity, reduced glutathione(GSH), glutathione peroxidase(GPx), glutathione reductase(GR), glutathione S-transferase(GST), superoxide dismutase(SOD) and catalase(CAT) levels were significantly decreased in MTX treated group. These alterations were improved by MEL and BA treatment, whereas no improvement was noticed in UDCA treatment. Conclusions: BA may be as promising as MEL in the hepatoprotection against MTX toxicity through their antioxidant and radical scavenging activities. In addition, it is not recommended to co-administer UDCA with MTX as it enhanced inflammation and damage to the liver.

关键词： Methotrexate Hepatotoxicity Melatonin Balanites aegyptiaca Ursodeoxycholic acid

Homes or Just Houses: The Housing Needs of Female-Headed Households in Egypt

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Journal of Building Construction and Planning Research 2018年第3期6卷 138-150页

作者： Reem Hamad ahmed S. Abd Elrahman ayat Ismail Department of Urban Planning and Design Faculty of Engineering Ain Shams University Cairo Egypt

With the drastic rise in divorce rates in Egypt in the last few decades, targeting female-headed households as new housing segment is becoming increasingly crucial. Female-headed households are categorized as part of the housing vulnerable groups supported by the government. The housing needs, preferences and the market navigation patterns of this group are the study matter of this paper. While this group shares similarities in the housing needs with the two-parent families there are defined differences in the housing presences and market navigation patterns of the two groups. The paper also sheds the light on how the social characteristics of the female-headed households determine the housing problems they face with the current market offerings. Then, it outlines a typology of the housing preferred by the female heads, with the aim of generating recommendations that would help create more inclusive and satisfactory housing market offerings tailored for them. The proximity of the workplace to the housing unit in addition to the presence of an active community center within the neighborhoods was on top of their housing demands.

关键词： Female-Headed Households Housing Social Housing in Egypt Socially Integrated Neighborhoods Female-Headed Households Inclusive Neighborhoods

An Efficient Method for Epileptic Seizure Detection in Long-Term EEG Recordings

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Journal of Biomedical Science and Engineering 2014年第12期7卷 963-972页

作者： Alaa Eldeen Mahmoud Helal ahmed Farag Seddik Mohammed Ali Eldosoky ayat Allah Farouk Hussein Biomedical Engineering Department Faculty of Engineering Helwan University Cairo Egypt Clinical Neurophysiology Department Faculty of Medicine Cairo University Cairo Egypt

Epilepsy is one of the most prevalent neurological disorders with no age, racial, social class, and neither national nor geographic boundaries. There are 50 million sufferers in the world today with 2.4 million new cases occur each year. Electroencephalogram (EEG) has become a traditional procedure to investigate abnormal functioning of brain activity. Epileptic EEG is usually characterized by short transients and sharp waves as spikes. Identification of such event splays a crucial role in epilepsy diagnosis and treatment. The present study proposes a method to detect three epileptic spike types in EEG recordings based mainly on Template Matching Algorithm including multiple signal-processing approaches. The method was applied to real clinical EEG data of epileptic patients and evaluated according to sensitivity, specificity, selectivity and average detection rate. The promising results illuminate that hybrid processing approaches in temporal, frequency and spatial domains can be a real solution to identify fast EEG transients.

关键词： Electroencephalogram (EEG) Seizure Detection Epilepsy Diagnosis