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Right prefrontal cortex is activated for perceiving postural limits: a functional near-infrared spectroscopy study

Health 2009年第3期1卷 239-243页

作者： Noriyuki Kamata Yoshimi Matsuo ayako matsuya Satoru Inoue Kazuo Abe 不详

The purpose of this study was to investigate neuronal mechanisms active during the percep-tion of forward postural limits in a standing po-sition and to specify fall-related brain activity using optical functional near-infrared spectros-copy. The study group included six right-handed, healthy female volunteers (range: 19, 20 years). The optical imaging device comprised 16 opto-des designed to provide 24-channel recording of changes in hemoglobin oxygenation. We meas-ured the changes of oxygenated hemoglobin levels in the frontal region when subjects per-ceived reachability in a standing position. Com- pared with those in other regions, the oxygen-ated hemoglobin levels in the right frontal region compatible with the right prefrontal cortex sig-nificantly increased. This result suggests that brain activities in the right prefrontal cortex are related to perception of reachability. Overesti-mation of postural limits has been reported as one of the risk factor for falling. This overesti-mation might be induced by dysfunction in the prefrontal cortex, resulting in a failure to inhibit a motor program that would have caused a loss of balance in reaching. Activation of the right prefrontal cortex may be a key factor for pre-venting accidental falls in the elderly and in pa-tients with neurological disorders.

关键词： Postural Limits Falls Functional Near-Infrared Spectroscopy (fNIRS) Prefrontal Cortex (PFC)

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氧气氧化2,6-二-(三甲基硅基)吡喃为6-三甲基硅基-α-吡喃酮

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有机化学 2013年第2期33卷 375-377页

作者：周德军 matsuya Yuji 河南理工大学物理化学学院焦作454000 富山大学药学部

开发出一种合成6-三甲基硅基α-吡喃酮的有效方法.在无溶剂无任何催化剂的氧气气氛中,室温条件下温和地将2,6-二-(三甲基硅基)吡喃通过氧化反应转化成6-三甲基硅基α-吡喃酮,并且给出了该反应可能的机理.

关键词： 6-三甲基硅基α-吡喃酮氧化反应机理

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A Packet I/O Architecture for Shell Script-based Packet Processing

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China Communications 2014年第2期11卷 1-11页

作者： Yohei Kuga Takeshi matsuya Hiroaki Hazeyama Kenjiro Cho Rodney Van Meter Osamu Nakamura The Graduate School of Media and Governance Keio University 5322 Endo Fujisawa 252-0882 Kanagawa Japan The Graduate School of Information Science Nara Institute of Science and Technology Takayama 8916-5 Nara Japan IIJ Research Lab Takebashi Yasuda Bldg 3F. 3-13 Kanda Nishikicho Chiyoda-ku Tokyo 1010054 Japan Faculty of Environment and Information Studies Keio University 5322 Endo Fujisawa 252-0882 Kanagawa Japan

We propose a new scripting model for rapid and easier development of packet processing using shell *** this paper we present EtherPIPE,a character network I/O device,that allows the programmer to access network traffic data as a file through UNIX *** setting a UNIX pipe "|" from or to EtherPIPE's output or input with UNIX commands,packets can be easily processed,executing functions such as packet filtering,packet capturing,generating arbitrary packets,and rewriting header *** order to prove the utilities of our model,we have developed FPGA-based EtherPIPE adapter using a commodity FPGA card and a character device driver featuring new offloading *** our prototype implementation,packet scripting works at 1Gbps wire-speed,receiving packets with precise hardware *** paper argues for use cases of the EtherPIPE,and discusses enhanced formats of character devices for easier network scripting.)

关键词：数据包捕获脚本字符设备驱动程序分组处理基础架构 UNIX 文件命令

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Engineering of Carbonate Apatite Bone Substitute Based on Composition-Transformation of Gypsum and Calcium Hydroxide

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Engineering（科研） 2010年第5期2卷 344-352页

作者： Ika D. Ana Shigeki matsuya Kunio Ishikawa 不详

Even though a lot of research has been carried out concerning the preparation of carbonate apatite (CHA), they were related to CHA in the form of powder. In the present study, macroporous CHA bone substitutes were prepared through composition-transformation of gypsum and Ca-hydroxide. Here, we investigated the effect of added Ca-hydroxide to gypsum, carbonation periods, and hydrothermal temperatures for phosphatization to understand the basic principle of composition-transformation of gypsum added Ca-hydroxide to fabricate CHA bone substitutes. The specimens were characterized in terms of chemical and physical properties, such as extent of transformation of macroporous gypsum added Ca-hydroxide into CHA body, type and content of carbonate, and crystal morphology. It was observed that the transformation was faster with higher hydrothermal temperature. However, higher hydrothermal temperature caused de-carbonation phenomena which resulted in the lack of carbonate ions of the product. Moreover, the higher the percentage of Ca-hydroxide added to gypsum, caused the complete transformation of gypsum into CHA to be slower. These findings have been applied to the standard fabrication procedure of carbonate apatite, which in turn will allow scaling up process, and will be provided for biomedical purposes for the Indonesian community.

关键词： Carbonate Apatite (CHA) Bone Substitute Composition-Transformation Gypsum Calcium Hydroxide

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Does an “Overactive to Underactive Bladder Transition” Phenomenon Exist in a Rat Lumbar Spinal Canal Stenosis Model?

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Open Journal of Urology 2015年第5期5卷 57-64页

作者： Noritoshi Sekido Jun Kida Daisuke Wakamatsu Hiroki Okada Hidekazu matsuya Department of Urology School of Medicine Faculty of Medicine Toho University Medical Center Ohashi Hospital Tokyo Japan Group2 Discovery Research Laboratories Ono Pharmaceutical Co. Ltd. Osaka Japan

Purpose: To investigate the association between the maximum cystometric capacity (MCC) and other cystometric parameters in lumbar canal stenosis (LCS) rats. Material and Methods: One small hole was drilled at the fifth lumbar vertebral arch (Sham), and a rectangular piece of silicone rubber was then placed in the epidural space (LCS) of Wister rats. Two weeks after surgery, awake cystometry was performed. LCS rats were divided into three groups: Group A (n = 5, MCC 1.81 mL). Cystometric parameters were investigated in sham and LCS groups. Results: MCC did not significantly correlate to the frequency of non-voiding contractions (NVCs), voided volume (VV), or maximum intravesical pressure during voiding (Pmax), but significantly positively correlated to postvoid residual urine volume (PVR) and residual urine rate (RUR) (Spearman’s correlation coefficients (ρ) = 0.8973 (p < 0.0001) and 0.4915 (p = 0.0068), respectively). Compared with the sham rats, LCS rats in each group revealed significantly smaller VV, larger RUR, and lower Pmax. On the other hand, among LCS rats, VV, RUR, and Pmax were not significantly different. The frequency of NVCs in each LCS group was not significantly different from that in sham-operated rats (Tukey-Kramer’s HSD test). However, a Jonckheere-Terpstra trend test revealed a significant trend toward higher NVCs in the order of sham, Groups C, B, and A (p = 0.036). Conclusions: LCS rats showed the same degree of detrusor underactivity regardless of MCC. NVCs did not significantly increase in LCS rats with decreased MCC, but the trend toward higher NVCs with smaller MCC was significant.

关键词： Underactive Bladder Detrusor Underactivity Lumbar Canal Stenosis Animal Model Overactive Bladder

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一种有效合成5,7-二甲氧基-1-茚酮的方法

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化学通报 2013年第3期76卷 286-288页

作者：周德军松谷裕二河南理工大学物理化学学院焦作454000 富山大学药学部

成功开发一种由容易得到的2-(3,5-二甲氧基苄基)丙二酸二乙酯为原料合成5,7-二甲氧基1-茚酮的有效新方法。将原料溶解于甲磺酸中,加热到100℃反应2 h收率可以达到95%。本反应所需原料廉价、后处理简单、对设备要求不高,适用于工业化生... 详细信息

成功开发一种由容易得到的2-(3,5-二甲氧基苄基)丙二酸二乙酯为原料合成5,7-二甲氧基1-茚酮的有效新方法。将原料溶解于甲磺酸中,加热到100℃反应2 h收率可以达到95%。本反应所需原料廉价、后处理简单、对设备要求不高,适用于工业化生产。另外,文中还提出了该反应可能的反应机理。

关键词： 5,7-二甲氧基-1-茚酮甲磺酸反应机理

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