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Liver transplantation for hepatitis B virus: Decreasing indication and changing trends

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World Journal of Gastroenterology 2015年第26期21卷 8140-8147页

作者： Waleed Al-hamoudi hussien Elsiesy Abdulrahman Bendahmash Nasser Al-masri Safiyya Ali Naglaa Allam Mohammed Al Sofayan Hamad Al Bahili Mohammed Al Sebayel Dieter Broering Sammy Saab Faisal Abaalkhail Gastroenterology Unit Department of MedicineCollege of MedicineKing Saud University Department of Liver Transplantation and Hepatobiliary Surgery King Faisal Specialist Hospital and Research Center National Liver Institute Menoufeya University David Geffen School of Medicine UCLA

AIM: To evaluate the indication and outcome of hepatitis B virus(HBV)-related liver transplantation(LT) in the era of newer antiviral ***: We collected data on all patients who underwent transplantation at King Faisal Specialist Hospital and Research *** data included demographic,perioperative and long-term postoperative follow-up data including viral serological markers,HBV DNA,and repeated liver *** January 1990 and January 2012,133 patients(106 males and 27 females) underwent LT for HBV-related cirrhosis at our *** patients were followed up frequently during the first year following transplantation,according to our standard protocol; follow-up visits occurred every 3-6 mo *** infection was definedas re-emergence of HBV-DNA or hepatitis B surface antigen(HBs Ag) while on *** patients transplanted prior to 1992 did not receive immediate posttransplant anti-HBV prophylaxis; all other patients were treated with HBIG and at least one nucleos(t)ide ***: One hundred and thirty-three patients underwent LT for HBV and were followed for a median of 82 mo(range: 1-274).The rates of post-LT survival and HBV recurrence during the follow-up period were 89% and 11%,*** following factors were associated with disease recurrence: younger age(44.3 ± 16.2 years vs 51.4 ± 9.9 years,P = 0.02),positive pretransplant hepatitis B e antigen(HBe Ag)(60% vs 14%,P < 0.0001),detectable pretransplant HBV DNA(60% vs 27%,P = 0.03),positive posttransplant HBs Ag(80% vs 4%,P < 0.0001) and positive posttransplant HBe Ag(27% vs 1%,P < 0.0001).Forty-four(33%) patients had hepatocellular carcinoma(HCC).In the first(pre-2007) group,HBV was the second leading indication for LT after hepatitis C virus infection.A total of 64 transplants were performed,including 46(72%) for decompensated HBV cirrhosis,12(19%) for decompensated cirrhosis complicated by HCC and 6(10%) for compensated cirrhosis complicated by ***

关键词： Hepatitis B Hepatitis C Non-alcoholicsteatohepatitis Liver transplantation Hepatocellularcarcinoma

Increased IgG Rheumatoid Factor-Positivity in the Asian Rheumatoid Arthritis Patients Irrespective of Ethnicity

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Open Journal of Rheumatology and Autoimmune Diseases 2014年第1期4卷 43-51页

作者： Chun Lai Too Johan Ronnelid Yuslina Mat Yusoff Jasbir Singh Dhaliwal Nor Ashikin Jinah Abqariyah Yahya Heselynn hussien Wahinuddin Sulaiman Per Tobias Larsson Shahnaz Murad Institute for Medical Research Kuala LumpurMalaysia Rheumatology Unit Department of MedicineKarolinska InstitutetStockholmSweden Department of Immunology Genetics and PathologyUppsala UniversityUppsalaSweden Department of Medicine Putrajaya HospitalWilayah PersekutuanMalaysia Department of Medicine Hospital Raja Perempuan BainunIpohMalaysia

Aim of Work: Initial observations implied IgG rheumatoid factor (RF) to be common among Malaysian rheumatoid arthritis (RA) patients. We tested this hypothesis and used a multiethnic RA cohort (Malays, Chinese and Indians) to investigate whether the IgG RF predominance might be genetically or environmentally determined. Patients and Methods: 556 serum samples comprising 171 patients classified as RA according to the 1987 ACR criteria, 60 patients with other rheumatic diseases and 325 non-rheumatic controls were tested for IgG RF, IgM RF and anti-CCP by ELISA. The findings were then tested in a larger RA case-control cohort (n = 1844). Results: IgG RF predominated over IgM RF in all the investigated ethnic groups. The sensitivity, specificity, and diagnostic accuracy of IgG RF (55.6%, 91.2% and 80.2%, respectively) were superior compared to IgM RF, but comparable to anti-CCP. IgG RF was however, also increased in the Malaysian controls, but the IgG RF superiority over IgM RF was still apparent after cutoff adjustment according to the 1987 ACR criteria. Autoantibody levels did not differ between the three ethnic groups. The Receiver Operating Characteristics (ROC) curves showed larger areas under the curves for IgG RF (0.826) and for anti-CCP (0.867) than for IgM RF (0.737). Review of the literature showed consistently higher sensitivity for IgG RF in studies of Asian RA patients as compared to Caucasian and African-American studies. Conclusion: Increased frequency of IgG RF-positive in RA populations with different genetic background living in Malaysia argues for an environmental factor selectively amplifying the IgG RF response.

关键词： Rheumatoid Arthritis(RA) IgG RF IgM RF Anti-Cyclic Citrullinated Peptide(Anti-CCP) Asia Ethnicity

Endoscopic resection of superficial bowel neoplasia:The unmet needs in the Egyptian practice

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World Journal of Gastrointestinal Endoscopy 2022年第4期14卷 235-249页

作者： Mohamed H Emara Mariam Zaghloul Haidi Karam-Allah Ramadan Salem Youssef Mohamed Mohammed Tag-Adeen Ahmed Alzamzamy Mohamed Alboraie Ahmad Madkour Ahmed Youssef Altonbary Tarik I Zaher Ahmed Abo Elhassan Nermeen Abdeen Mohammed hussien Ahmed Department of Hepatology Gastroenterology and Infectious DiseasesKafrelsheikh UniversityKafr Elshiekh 33516Egypt Department of Tropical Medicine and Gastroenterology Assiut UniversityAssiut 71515Egypt Department of Internal Medicine Faculty of MedicineGastroenterology and Hepatology UnitZagazig UniversityZagazig 44519Egypt Division of Gastroenterology and Hepatology Department of Internal MedicineSouth Valley UniversityQena Faculty of MedicineQena 83523Egypt Department of Gastroenterology and Hepatology Maadi Armed Forces Medical ComplexMilitary Medical AcademyCairo 11841Egypt Department of Internal Medicine Al-Azhar UniversityCairo11884Egypt Department of Endemic Medicine Helwan UniversityCairo 11795Egypt Department of Gastroenterology and Hepatology Mansoura UniversityMansoura 35516Egypt Department of Tropical Medicine Zagazig UniversityZagazig 44519Egypt Department of Tropical Medicine Suez Canal UniversityIsmailia 41522Egypt Department of Tropical Medicine Alexandria UniversityAlexandria 21526Egypt

BACKGROUND Management of superficial bowel neoplasia(SBN)in early stages is associated with better *** last few decades experienced a paradigm shift in the management of SBN with the introduction of advanced endoscopic resection techniques(ERTs).However,there are no clear data about the aspects of ERTs in Egypt despite the growing gastroenterology *** To investigate the knowledge,attitude,and practice of ERTs toward management of SBN among Egyptian practitioners and the suitability of the endoscopy units’infrastructures toward these *** An online 2-pages questionnaire was *** first page comprised demographic data,and questions for all physicians,about the knowledge(11 questions)of and attitude(5 questions)toward ERTs as a therapeutic option for *** second page investigated the practice of ERTs by endoscopists(6 questions)and the infrastructures of their endoscopy units(14 questions).The survey was disseminated through July 2021 and the data were collected in an excel sheet and later analyzed *** The complete responses were 833/2300(36.2%).The majority of the participants were males(n=560,67.2%),middle-aged(n=366,43.9%),consultants(n=464,55.7%),gastroenterologists(n=678,81.4%),spending≥15 years in practice(n=368,44.2%),and were working in university hospitals(n=569,68.3%).The majority correctly identified the definition of SBN(88.4%)and the terms polypectomy,endoscopic mucosal resection(EMR),and endoscopic submucosal dissection(ESD)(92.1%,90.2%,and 89.1%respectively).However,26.9%,43.2%and 49.5%did not recognize the clear indication of polypectomy,EMR,and ESD *** 68.1%of physicians are convinced about the ERTs for management of SBN;only 8.9%referred all candidate cases for *** 76.5%of endoscopists had formal training in the basic polypectomy techniques while formal training for EMR and ESD was encountered only in 31.9%and 7.2%*** 71.6%and 88.4%of endoscopists did not per

关键词： Endoscopic submucosal dissection Endoscopic mucosal resection Polypectomy Superficial bowel neoplasia Egypt

Erratum to “Association between the Presence of Serumanti-Cardiolipin Antibodies and Infertility” [Journal of Biosciences and Medicines 4 (2016) 95-100]

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Journal of Biosciences and Medicines 2017年第5期5卷 56-56页

作者： Rafah Oday hussien Abdul-Razak Sh. Hasan Department of Health Community Technical Institute Baqubah Diyala Iraq Department of Microbiology College of Medicine Diyala University Diyala Iraq

The original online version of this article (Hasan, A.-***., Hwaid, A.H. and Mahdy, Z.H. (2016) Association between the Presence of Serumanti-Cardiolipin Antibodies and Infertility. Journal of Biosciences and Medicines, 4, 95-100. http://***/10.4236/jbm.2016.41011) was published as a mistake in the names of researchers in authorship paper. To reflect the contribution and responsibility of the first author as well as the affiliations of the authors at the time of the study, we have revised the authorship and author affiliations of this article. The author wishes to correct the errors as: Rafah Oday hussien1, Abdul-Razak Sh. Hasan2 1Department of Health Community, Technical Institute, Baqubah, Diyala, Iraq 2Department of Microbiology, College of Medicine, Diyala University, Diyala,

关键词： Anticardiolipin Antibodies Primary Infertility Secondary Infertility

Frequency and Antimicrobials Susceptibility Pattern of <i>Staphylococcus aureus</i>Associated with Wound Infections in Surgery Department, Wad Madani Teaching Hospital, Sudan

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Pharmacology & Pharmacy 2021年第12期12卷 334-343页

作者： Sanaa M. Yousif Adam D. Abakar Bakri Y. M. Nour Salma O. Ibrahim Omer M. Abu Elhasan Mirgani A. Yousif Sitelbanat Yassin Hajer M. hussien Mohamed Taj-Eldin Elhadi A. Ahmed National Blood Bank Ministry of Health Khartoum Sudan Department of Medical Parasitology Faculty of Medical Laboratory Sciences University of Gezira Wad Medani Sudan Department of Medical Microbiology Faculty of Medical Laboratory Sciences University of Gezira Wad Medani Sudan Wad-Madani College of Medical Sciences and Technology Wad Medani Sudan Faculty of Pharmacy University of Gezira Wad Medani Sudan

Background: Most community and hospital acquired infections are due to Staphylococcus aureus, these infections involve both local suppurative and systemic conditions. There is an increase in the incidence rates of acquiring resistant strains of Staphylococcus aureus in hospitals and community in Sudan. This study aims to detect frequency of Staphylococcus aureus isolated from surgical-sites infections (SSIs) and traumatic wounds, and to determine susceptibility to commonly used drugs. Methods: Prospective cross-sectional laboratory based study was followed, 250 patients admitted to Surgery Departments at Wad Madani Teaching Hospitals during 2019 and 2020 were recruited;with clinical manifestation of SSIs and or/traumatic wounds. Swab sample was taken from each participant and incubated aerobically on mannitol salt agar. Biochemical tests and 16rRNA gene used for Staphylococcus aureus identification. Antimicrobial susceptibility was accomplished using Kirby Bauer disc diffusion technique. Results: Infection rate of wounds in males and females equal 71% (17/250) and 29% (73/250), while infection rate in the age group of 41 to 60 y

关键词： Staphylococcus aureus Surgical-Sites Wounds Meropeneme Sudan

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5种不同去牙面正畸残余粘接剂方法比较

上海口腔医学 2019年第2期28卷 136-140页

作者：钮晔安贝尔敬怡张泽宇肖立伟中南大学湘雅二医院湖南长沙410000

目的 :通过比较5种方法去除牙面残余正畸粘接剂对牙面的影响及操作所用时间,为筛选最佳去牙面粘接树脂方法提供参考。方法:选用正畸治疗需要拔除的健康前磨牙40颗,按不同的去牙面粘接剂方法随机分为5组,每组8颗。在常规粘接托接槽并去... 详细信息

目的 :通过比较5种方法去除牙面残余正畸粘接剂对牙面的影响及操作所用时间,为筛选最佳去牙面粘接树脂方法提供参考。方法:选用正畸治疗需要拔除的健康前磨牙40颗,按不同的去牙面粘接剂方法随机分为5组,每组8颗。在常规粘接托接槽并去粘接后,分别用碳化钨钻(A组)、碳化钨钻+矽粒子(B组)、金刚砂钻(C组)、金刚砂钻+矽粒子(D组)、矽粒子(E组)做牙面处理,记录各组操作时间(T),并在扫描电镜(SEM)下观察、照相,记录釉质损伤指数(enamel damage index)。采用SPSS20.0软件包对操作时间T及EDI分别进行单因素方差分析及非参数秩变换分析。结果:各组EDI排序为C组>D组>A组>B组>E组,差异具有统计学意义(PD组>B组>A组>C组,差异具有统计学意义(P<0.05)。结论 :用高速碳化钨钻加矽粒子去除残余粘接剂对釉质损伤较小且操作时间合理,值得临床推荐。

关键词：去粘接矽粒子釉质损伤指数扫描电镜

Caring psychiatric patients and its impact on nurses’behavior:a cross-sectional quantitative method study in Saudi Arabia

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Nursing Communications 2023年第14期7卷 1-7页

作者： Faten Mohammed Islam Khotany Najla Eid Alharbi Ghadeer Hassan Mahdi Moodhi Neda Basher Alazimi Hajer Marei Mahammed Rabaiy Aisha ayesh Alotaibi Nawar Aqeel Alrashidi Marwah Suliman Aljohani Fatimah Ahmed Alhazemi Ghazaile Jameel Khayat Samirah Ali Kaddaf Laila hussien Hakami Saeed Atiah Almalki Abdulaziz Mohammad Islam Khotani Feryal Mohammad Islam Kotany Mofreh Alsahil Alruwaili Makkah Health Cluster Makkah regionAl Hamra street 7853Saudi Arabia Deputy of Nursing supervisor Aljamoum Health SectorMakkahSaudi Arabia Sabya General Hospital South regionJazanSaudi Arabia Community Health Nursing Primary Health CareAlqaseemUnizahSaudi Arabia Department of Nursing Jeddah King Abdullah Medical ComplexWestern regionSaudi Arabia Nursing supervisor of PHCs in Aljamoum Health Sector MakkahSaudi Arabia Department of Nursing Khafji General HospitalEastern regionSaudi Arabia Department of Nursing Forensic MedicineWestern regionMadinahSaudi Arabia South region-Jazan Dental Centre JazanSaudi Arabia King Fahad Hospital MakkahSaudi Arabia Department of Nursing Primary Care Health Center in Al RashidiyaWestern regionMakkahSaudi Arabia OBGYNE and Paediatric supervisor at Jazan General Hospital Jizan citySaudi Arabia Erada and Mental Health Complex TaifMecca regionSaudi Arabia Makkah Health Cluster MHCSaudi Arabia Makkah Health Cluster PHCSaudi Arabia Ministry of Health/Aljouf Health Affairs Sakaka AljoufQara-Alsalam 5108Saudi Arabia.

Objective:The present study aimed to address the care of psychiatric patients and its impact on nurses’behavior in Saudi ***:A cross-sectional quantitative questionnaire-based study was *** study was carried out in various government hospitals across different regions of Saudi ***:A total of 73 nurses participated in the study,with male nurses comprising the majority(61.6%)compared to *** a young nurse or with few years of work experience is linked with more predilection towards preventive behaviour and/or physical activity.A significant mean difference was observed,indicating higher scores for preventive behavior among females(female 14.93±5.82 *** 11.56±5.48,P=0.015).The Bonferroni post hoc multiple comparisons did not reveal any statistical significance for single ***(P=0.618),single ***(P=0.223),and married ***(P=0.020).Conclusion:The study results demonstrated a significant impact of caring for psychiatric patients on nurses’*** is concerning because psychological and mental health strain has been shown to contribute to unhealthy lifestyle habits,such as physical inactivity and sleep deprivation,which,in turn,can contribute to the increasing incidence and prevalence of chronic *** interventions targeting psychiatric and mental health nurses should be designed and examined to emphasize the importance of healthy lifestyle choices and an active lifestyle.

关键词： nurses psychiatric patients behaviour Saudi Arabia

Exploring the current provision of pancreatic transplantations in lowand middle-income countries:Current landscape,challenges,future prospects

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World Journal of Gastrointestinal Pathophysiology 2024年第6期15卷 1-10页

作者： Hareesha Rishab Bharadwaj Joecelyn Kirani Tan Syed Hasham Ali Muhammad Hamza Shah Aderinto Nicholas Khabab Abbasher hussien Mohamed Ahmed Khansa Irfan Priyal Dalal Aashna Mehta Wireko Andrew Awuah Arkadeep Dhali Faculty of Biology Medicine and Health University of ManchesterManchester M139PLUnited Kingdom Faculty of Medicine University of St AndrewsSt Andrews KY169AJUnited Kingdom Faculty of Medicine Dow Medical CollegeKarachi 74200Pakistan School of Medicine Queen's University BelfastBelfast BT71NNUnited Kingdom Department of Medicine and Surgery Ladoke Akintola University of TechnologyOgbomosho 210214OyoNigeria Faculty of Medicine University of KhartoumKhartoum 0000Sudan School of Medicine University of Central LancashirePreston PR21SGUnited Kingdom Faculty of Medicine and Surgery University of DebrecenDebrecen 4032Hungary Faculty of Medicine and Surgery Sumy State UniversitySumy 40007Ukraine Department of Gastroenterology Sheffield Teaching Hospitals NHS Foundation TrustRoyal Hallamshire HospitalSheffield S102JFUnited Kingdom School of Medicine and Population Health University of SheffieldSheffield S102HQUnited Kingdom Deanery of Clinical Sciences The University of EdinburghEdinburgh EH164SBUnited Kingdom Leeds Institute of Health Sciences University of LeedsLeeds LS29LNUnited Kingdom

This comprehensive review addresses the global health challenge of disparities in pancreas transplant access,particularly in low-and middle-income countries(LMICs)compared to high-income *** advancements in surgical techniques and immunosuppression for procedures like simultaneous pancreas-kidney,pancreas-after-kidney,and pancreas-transplant alone,LMICs face significant challenges,including limited infrastructure,financial constraints,and a shortage of skilled medical *** after brain death remains constrained by sociocultural ***-specific analyses highlight progress in Latin America,Asia,Russia,and South Africa,showcasing the regional disparities in access and *** prospects involve minimally invasive surgeries,telemedicine for enhanced post-operative care,international collaborations with organizations like the European Union of Medical Specialists,and robust funding networks to improve organ *** conclusion,the review underscores the importance of multifaceted strategies to address economic,sociocultural,and infrastructural barriers,aiming to improve accessibility,quality,and effectiveness of pancreas transplantation services in LMICs.

关键词： Pancreatic transplantation Diabetes mellitus Global health Low-and middle-income countries Transplant surgery