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Design and Optimization of Steel Car Body Structures via Local Laser-Strengthening

Engineering（科研） 2016年第5期8卷 276-286页

作者： Markus Wagner axel jahn Eckhard Beyer Daniel Balzani Division of Laser Beam Joining Fraunhofer Institut f. Werkstoff- und Strahltechnik Dresden Germany Dresden Center for Computational Materials Science Dresden University of Technology Dresden Germany Institute of Mechanics and Shell Structures Dresden University of Technology Dresden Germany

Continuously rising demands of legislators require a significant reduction of CO2-emission and thus fuel consumption across all vehicle classes. In this context, lightweight construction materials and designs become a single most important factor. The main engineering challenge is to precisely adapt the material and component properties to the specific load situation. However, metallic car body structures using “Tailored blanks” or “Patchwork structures” meet these requirements only insufficiently, especially for complex load situations (like crash). An innovative approach has been developed to use laser beams to locally strengthen steel crash structures used in vehicle bodies. The method tailors the workpiece hardness and thus strength at selected locations to adjust the material properties for the expected load distribution. As a result, free designable 3D-strengthening-patterns surrounded by softer base metal zones can be realized by high power laser beams at high processing speed. The paper gives an overview of the realizable process window for different laser treatment modes using current high brilliant laser types. Furthermore, an efficient calculation model for determining the laser track properties (depth/width and flow curve) is shown. Based on that information, simultaneous FE modelling can be efficiently performed. Chassis components are both statically and cyclically loaded. Especially for these components, a modulation of the fatigue behavior by laser-treated structures has been investigated. Simulation and experimental results of optimized crash and deep drawing components with up to 55% improved level of performance are also illustrated.

关键词： Automotive Lightweight Structures Local Laser Treatment Laser Beam Strengthening Crash Simulation Laser Strengthening Laser Hardening

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Multifaceted nature of membrane microdomains in colorectal cancer

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World Journal of Gastroenterology 2011年第6期17卷 681-690页

作者： Kristina A jahn Filip Braet Australian Centre for Microscopy and Microanalysis The University of Sydney

Membrane microdomains or lipid rafts are known to be highly dynamic and to act as selective signal transduction mediators that facilitate interactions between the cell's external and internal *** rafts play an important mediating role in the biology of cancer:they have been found in almost all existing experimental cancer models,including colorectal cancer (CRC),and play key regulatory roles in cell migration,metastasis,cell survival and tumor *** paper explores the current state of knowledge in this field by highlighting some of the pioneering and recent lipid raft studies performed on different CRC cell lines and human tissue *** this literature review,it becomes clear that membrane microdomains appear to be implicated in all key intracellular signaling pathways for lipid metabolism,drug resistance,cell adhesion,cell death,cell proliferation and many other processes in *** signal transduction pathways seem to originate directly from those peculiar lipid islands,thereby orchestrating the colon cancer cells' state and *** confirmed by recent animal and preclinical studies in different CRC models,continuing to unravel the structure and function of lipid rafts-including their associated complex signaling pathways-will likely bring us one step closer to better monitoring and treating of colon cancer patients.

关键词： Actin Caveolae Cytoskeleton Combined imaging Detergent-resistant membranes Drug targeting Electron microscopy Lipid domains Membrane rafts Prognosis Staging Tomography Lipid-mediated therapy

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Counting the SNAREs needed for membrane fusion

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分子细胞生物学报:英文版 2011年第4期3卷 204-205页

作者： Geert van den Bogaart Reinhard jahn Department of Neurobiology Max-Planck Institute for Biophysical ChemistryAm Fassberg 1137077 GottingenGermany

SNARE proteins mediate most membrane fusion reactions in eukaryotic cells,and are thereby vital for many functions,including synaptic transmission,cell growth,and ***,until recently it was still unclear how many of these proteins are required to catalyze membrane fusion in *** a recent Science paper,Mohrmann et al.(2010)elegantly show that in chromaffin cells,three SNARE complexes are required for the synchronous release of granules,whereas only a single SNARE complex is sufficient for overall release.

关键词： release thereby complexes

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Isotopic characteristics of the postorogenic granites in orogenic belt of northern China and their implications in crustal growth

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Chinese Science Bulletin 1998年第5期43卷 420-424页

作者： Fuyuan Wu Borming jahn Qiang Lin Changchun Univ Sci & Technol Dept Earth Sci Changchun 130061 Peoples R China Univ Rennes 1 F-35042 Rennes France

The orogenic belt of northern China is characterized by widely developed postorogenic Ⅰ fractionated and A-type granites in the Phanerozoic. The isotopic data display relatively high ε Nd(t) and 206Pb/ 204Pb values and low I Sr ratio. The low T DM model ages (<100 Ma) suggest that the Neo-Proterozoic-Phanerozoic is one of the main stages in the continental growth.

关键词： orogenic belt of northern China granites isotope crustal growth.

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Unlocking the ultrastructure of colorectal cancer cells in vitro using selective staining

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World Journal of Gastroenterology 2010年第22期16卷 2743-2753页

作者： Joanna M Biazik Kristina A jahn Filip Braet Australian Key Centre for Microscopy and Microanalysis Madsen Building F09 The University of Sydney

AIM: To characterise differences between three widely used colorectal cancer cell lines using ultrastructural selective staining for glycogen to determine variation in metastatic properties. METHODS: Transmission electron microscopy was used in this investigation to help identify intracellular structures and morphological features which are precursors of tumor invasion. In addition to morphological markers, we used selective staining of glycogen as a marker for neoplastic cellular proliferation and determined whether levels of glycogen change between the three different cell lines. RESULTS: Ultrastructural analysis revealed morphological differences between the cell lines, as well as differentiation into two sub-populations within each cell line. Caco-2 cells contained large glycogen deposits as well as showing the most obvious morphological changes between the two sub-populations. SW480 cells also contained large glycogen stores as well as deep cellular protrusions when grown on porous filter membranes. HT-29 cells had trace amounts of glycogen stores with few cellular projections into the filter pores and no tight junction ***: Morphology indicative of metastatic properties coincided with larger glycogen deposits, providing strong evidence for the use of selective staining to determine the neoplastic properties of cells.

关键词： Cancer Colorectal Electron microscopy Glycogen Potassium ferrocyanide

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Diachroneity of continental subduction and exhumation:Constraints from the Permian-Triassic HP metamorphic terrane in the Tongbai orogen, central China

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Chinese Science Bulletin 2013年第35期58卷 4397-4404页

作者： LIU XiaoChun jahn Bor-Ming LI SanZhong Key Laboratory of Paleomagnetism and Tectonic Reconstruction of Ministry of Land and Resources Institute of GeomechanicsChinese Academy of Geological Sciences Department of Geosciences Taiwan University College of Marine Geosciences Ocean University of China

High-pressure(HP)metamorphic terrane in the Tongbai orogen comprises two HP slices(I and II)and a tectonic mélange zone in the northeast and a blueschist-greenschist zone in the *** slice I is represented by the northern and southern eclogite zones on the two sides of the Tongbaishan *** slice II is represented by retrograded eclogite-bearing metamorphic enclaves in Cretaceous gneissic granites in the Tongbai Complex.U-Pb,Lu-Hf,Rb-Sr and40Ar/39Ar multichronometric data indicate that the peak metamorphism of HP slice I took place at^255 Ma,whereas the metamorphic ages of HP slice II are as young as232–220 *** contrast,the tectonic mélange zone near the suture was metamorphosed at^256 *** a diachroneity of different slices across the direction of the orogen in the Hong’an-Dabie-Sulu HP/UHP terrane is ubiquitous,and it can be interpreted by a syn-subduction detachment/exhumation ***,the metamorphic age of HP slice I in the Tongbai orogen is older than that of the equivalent HP slice in the Hong’an orogen by^15 Ma,suggesting that the diachroneity may have also existed along the direction of the orogen.A seesaw-type subduction/exhumation model is proposed to explain this age disparity and the subduction of the South China Block becomimg shallower towards the west.

关键词：超高压地体变质地体大陆俯冲中国南方造山带桐柏山穿时折返

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Major-effect candidate genes identified in cultivated strawberry(Fragaria×ananassa Duch.)for ellagic acid deoxyhexoside and pelargonidin-3-O-malonylglucoside biosynthesis,key polyphenolic compounds

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Horticulture Research 2020年第1期7卷 1109-1125页

作者： jahn Davik Kjersti Aaby Matteo Buti Muath Alsheikh NadaŠurbanovski Stefan Martens Dag Røen Daniel James Sargent Division of Biotechnology and Plant Health Norwegian Institute of Bioeconomy ResearchÅs N-1433Norway NOFIMA AS Norwegian Institute of Food Fisheries and Aquaculture ResearchÅs N-1433Norway Department of Agriculture FoodEnvironment and ForestryUniversity of FlorenceFlorenceItaly Graminor Breeding Ltd. N-2322 RidabuNorway Department of Plant Sciences Norwegian University of Life SciencesRidabu N-1432ÅsNorway NIAB-EMR East MallingME196BJ KentUK Department of Food Quality and Nutrition Fondazione Edmund MachCentro Ricerca e InnovazioneVia E.Mach 138010 San Michele all’AdigeTNItaly Department of Genetics Genomics and BreedingNIAB-EMREast MallingME196BJ KentUK

Strawberries are rich in polyphenols which impart health benefits when metabolized by the gut microbiome,including anti-inflammatory,neuroprotective,and antiproliferative *** addition,polyphenolic anthocyanins contribute to the attractive color of strawberry ***,the genetic basis of polyphenol biosynthesis has not been extensively studied in *** this investigation,ripe fruits from three cultivated strawberry populations were characterized for polyphenol content using HPLC-DAD-MSn and genotyped using the iStraw35k *** and QTL analyses identified genetic loci controlling polyphenol *** were identified on four chromosomes for pelargonidin-3-O-malonylglucoside,pelargonidin-3-O-acetylglucoside,cinnamoyl glucose,and ellagic acid deoxyhexoside ***/absence of ellagic acid deoxyhexoside and pelargonidin-3-O-malonylglucoside was found to be under the control of major gene loci on LG1X2 and LG6b,respectively,on the F.×ananassa linkage *** of gene predictions in the *** reference genome sequence identified a single candidate gene for ellagic acid deoxyhexoside biosynthesis,while seven malonyltransferase genes were identified as candidates for pelargonidin-3-O-malonylglucoside *** malonyltransferase genes were identified in the F.×ananassa‘Camarosa’genome sequence but the candidate for ellagic acid deoxyhexoside biosynthesis was absent from the‘Camarosa’*** study demonstrated that polyphenol biosynthesis in strawberry is,in some cases,under simple genetic control,supporting previous observations of the presence or absence of these compounds in strawberry *** has also shed light on the mechanisms controlling polyphenol biosynthesis and enhanced the knowledge of these biosynthesis pathways in *** above findings will facilitate breeding for strawberries enriched in compounds with beneficial health effects.

关键词： straw polyphenol breeding

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Age of the Beishan eclogites and its tectonic implications

Age of the Beishan eclogites and its tectonic implications

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中国矿物岩石地球化学学会第13届学术年会

作者： Bor-ming jahn Department of Geosciences National Taiwan University

＜正＞The Beishan orogen is situated in the southern margin of the Central Asian Orogenic Belt（CAOB）.It is connected with the Tianshan orogen to the west and the Mongolia-Xing’anling orogen to the *** orogen exhibits a well-preserved Neoproterozoic to Late Paleozoic sequence containing ophiolites,accretionary complexes and eclogites.U-Pb zircon dating of eclogites yielded two concordant ages,（886±4） Ma for the cores and（465±10） Ma for the *** zircon cores display bright luminescence with homogeneous or planar/sector zoning,intermediate Th/U ratios（0.17～0.47）,and HREE-enriched patterns with negative Eu anomalies（Eu/Eu* =0.16～0.58）.These features,coupled with their formation temperatures of 680～710℃,suggest that the core age represents the time of an earlier upper amphibolite facies metamorphic *** contrast,the zircon rims

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Partial equilibrium of radiogenic and stable isotope systems in garnet peridotite during ultrahigh-pressure metamorphism

Partial equilibrium of radiogenic and stable isotope systems...

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中国科学院地质与地球物理研究所2003学术年会

作者： BOR-MING jahn Geosciences-Rennes Universite de Rennes 1Campus de Beaulieu35042 Rennes CedexFrance

A critical question in radiometric dating of metamorphic rocks is whether minerals used to define internal isochrons have achieved isotopic equilibrium during a given metamorphic event,followed by preservation of the equilibrium afterward.A garnet peridotite at Zhimafang in the Sulu terrane of eastern China shows incongruent U-Pb,Rb-Sr,and Sm-Nd *** SHRIMP U-Pb dating yielded an isochron age of 224±8 Ma,pointing to zircon growth during Triassic UHP meta-morphism. Two mineral assemblages gave consistent Rb-Sr internal isochron ages of 201±4 and 205±4 Ma,but much older Sm-Nd internal isochron ages of 376±16 and 378±24 ***, the Sm-Nd radiometric system fails to reequilibrate among the dated minerals during the Triassic UHP metamorphic event for the garnet *** result is confirmed by the state of oxygen isotope equilibrium(or disequilibrium) among the constituent minerals in the garnet *** particular,garnet is not in oxygen isotope equilibrium with any other of the analyzed *** degree of oxygen isotope disequilibria among the other minerals varies from pair to *** isotope equilibrium is observed only between orthopyroxene and olivine for both samples and between phlogopite and clinopyroxene for one *** appears that the U-Pb,Rb-Sr,Sm-Nd,and O isotope systems in minerals of the garnet peridotite are in partial equilibrium during UHP metamor-phism, i.e.,equilibrium with respect to some isotopes and minerals,but not *** on available experimental diffusion data,our study of the combined U-Pb,Rb-Sr,Sm-Nd,and O isotope systems in the gamet peridotite demonstrates that the time scale for the UHP metamorphism and subsequent HP eclogite-facies recrystallization is possibly in the range of about 12 to 26 Ma,which was not long enough for the reequilibration of the Sm-Nd and 0 isotope systems,but just long enough for the reequilibration of the Rb-Sr isotope ***,the rate of Sr diffusion in phlogopite (t

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Design and Evaluation Tool for Operations and Maintenance Logistics Concepts for Offshore Wind Power Plants

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Journal of Energy and Power Engineering 2013年第11期7卷 2054-2059页

作者： Torsten Mansterberg Robert Rauer Carlos jahn Fraunhofer Center for Maritime Logistics and Services Hamburg 21073 Germany Institute of Maritime Logistics Hamburg University of Technology Hamburg 21073 Germany

In this article, the authors give an overview of different logistics concepts for operation and maintenance of OWPP （offshore wind power plants）. These can be generally classified into onshore based and offshore based concepts. The operation of OWPPs can still be improved as research has shown that the availability of OWPPs is low compared to onshore wind power plants. There are a few tools to calculate operating costs and to evaluate the different concepts. However, most tools have a weak focus on logistics although logistics account for a big share of the costs. The tool the authors are introducing in this article focuses on the logistics processes. It is first explained and then tested with an OWPP scenarin

关键词： Offshore wind energy offshore wind power plants operations and maintenance logistics concepts design and evaluationtool simulation.

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