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npj Computational Materials 2023年第1期9卷 2310-2321页

作者： Jong Hyun Jung Prashanth Srinivasan axel forslund Blazej Grabowski Institute for Materials Science University of StuttgartPfaffenwaldring 5570569 StuttgartGermany

Accurate prediction of thermodynamic properties requires an extremely accurate representation of the free-energy *** are twofold—first,the inclusion of the relevant finite-temperature mechanisms,and second,a dense volume–temperature grid on which the calculations are performed.A systematic workflow for such calculations requires computational efficiency and reliability,and has not been available within an ab initio framework so ***,we elucidate such a framework involving direct upsampling,thermodynamic integration and machine-learning potentials,allowing us to incorporate,in particular,the full effect of anharmonic *** improved methodology has a five-times speed-up compared to state-of-the-art *** calculate equilibrium thermodynamic properties up to the melting point for bcc Nb,magnetic fcc Ni,fcc Al,and hcp Mg,and find remarkable agreement with experimental data.A strong impact of anharmonicity is observed specifically for *** introduced procedure paves the way for the development of ab initio thermodynamic databases.

关键词： harmonic point prediction

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真爱无敌斯德哥尔摩笔店

室内设计与装修 2015年第4期 20-21页

作者： Lia forslund coco Form Us With Love

这间由瑞典本土设计公司Form Us With Love设计的笔店,是他们众多设计作品中很特殊的一个.和大多数的设计师一样,Form Us With Love的设计师对于文具,尤其是各种笔的热爱是很难用语言形容的.这个新开张的笔店更像是个画廊、一个工作室... 详细信息

这间由瑞典本土设计公司Form Us With Love设计的笔店,是他们众多设计作品中很特殊的一个.和大多数的设计师一样,Form Us With Love的设计师对于文具,尤其是各种笔的热爱是很难用语言形容的.这个新开张的笔店更像是个画廊、一个工作室、一个仓库.

关键词：斯德哥尔摩 Form 设计师设计作品工作室仓库

Could sport be part of pediatric obesity prevention and treatment? Expert conclusions from the 28th European Childhood Obesity Group Congress

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Journal of Sport and Health Science 2019年第4期8卷 350-352页

作者： Susanne Ring-Dimitriou Peter Krustrup Manuel J Coelho-E-Silva Jorge Mota Andera Seabra Carla Rego Artur Mazur Elpis Vlachopapadopoulou Margerita Caroli Marie-Laure Frelut Eva Erhardt Anders forslund Ema Boyland Daniel Weghuber David Thivel Department of Sport Science and Kinesiology Paris Lo dron-UniversitySalzburg 5020Austria Paediatric Practice Albi 81000France Department of Paediatrics University of PecsPecs 7600Hungary Department of Women's and Children's Health Uppsala UniversityUppsala 74192Sweden Appetite&Obesity Research Group Department of Psychological SciencesUniversity of LiverpoolLiverpoolL69 7ZAUK Department of Pediatrics Obesity Research UnitParacelsus Medical UniversitySalzburg 5020Austria Laboratory of the Metabolic Adaptations to Exercise under Physiological and Pathological Conditions Auvergne Regional Center for Human NutritionClermont A uvergne UniversityClermont-Ferrand 63000France European Childhood Obesity Group(ECOG) Brussels 1000Belgium Department of Sports Science and Clinical Biomechanics SDU Sport and Health Sciences Cluster(SHSC)University of Southern DenmarkOdense 5000Denmark Faculty of Sport Sciences and Physical Education University of CoimbraCoimbra 3000Portugal Research Centre in Physical Activity Health and Leisure(CIAFEL)Faculty of SportUniversity of PortoPorto 4000Portugal Hospital Center for Research in Health Technologies and Information Systems(CINTESIS)Faculty of MedicineUniversity of PortoPorto 4000Portugal Pediatric Department Clinical Provincial Hospital No.2 in Rzesz6wFaculty of MedicineUniversity of RzeszowRzeszow 35-301Poland Department of Endocrinology Children's Hosp.P.&A.KyriakouAthens 10431Greece Paediatric Department Brindisi HospitalBrindisi 72100Italy

The prevalence of pediatric obesity continues to increase worldwide,bringing with it various metabolic,functional,social,and psychological complications.1 Both the prevention and treatment of childhood obesity must be based on multidisciplinary approaches combining nutrition,physical activity(PA),and psychological support.2 As an essential element of these multicomponent strategies,regular physical activity has been acknowledged as having beneficial effects on children's and adolescents,body composition,physical fitness,and metabolic profile,as well as on their health-related quality of life,social and psychological health,and academic achievement.3,4 Given that only a relatively small proportion of children and adolescents meet the public health recommendations for PA,5 and given that weight loss exercise-based interventions suffer from a high attrition rate,there is a clear need for appropriate PAs.

关键词： pediatric obesity prevention treatment 28th European Childhood Obesity Group Congress

皮肤型人乳头瘤病毒DNA在皮肤肿瘤表面高检出,而在活检标本中检出率低

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世界核心医学期刊文摘（皮肤病学分册） 2005年第1期1卷 54-55页

作者： forslund O. Lindelf B. Hradil E. 崔荣 Department of Medical Microbiology Malmo University Hospital SE-205 02 Malmo Sweden

Genomes of human papillomaviruses (HPV) are common in biopsies from non-melanoma skin cancers but are also found on healthy skin and it is possible that HPV positivity in tumor biopsies by PCR maymerely reflect contamination of the lesion *** investigate this issue, 229 immunocompetent patients were tested for HPV DNA in swab samples collected on top of skin tumors and in biopsies of the same tumors, obtained after stripping with tape to remove superficial *** DNA was detected on top of 69%(159 of 229) of the lesions, and in 12%(28 of 229) of the stripped biopsies (p < 0.001).The difference was seen for all four types of tumors *** keratosis had 79%(34 of 43) HPV positivity on top of lesions versus 19%(eight of 43) in biopsies; actinic keratosis had 83%(38 of 46) HPV positivity on top versus 11%(five of 46) in biopsies; basal cell carcinoma had 63%(69 of 109) on top versus 8%(nine of 109) in biopsies and squamous cell carcinoma had 58%(18 of 31) on top versus 19%(six of 31) in *** DNA is common in superficial layers of lesions, but is not necessarily present throughout tumors.

关键词：皮肤肿瘤人乳头瘤病毒活检标本皮肤型脂溢性角化病基底细胞癌拭子角化症光化性鳞状细胞癌

Randomized Controlled Trial Of Hpv Testing In Primary Cervical Screening

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直结肠癌患者原发灶和肝脏转移灶的p53状态比较

24th International Papillomavirus Conference and Clinical Workshop

作者： Pontus Naucler Walter Ryd Sven Tomberg Anders Strand Goran Wadell Kristina Elfgren Thomas Rodberg Born Strander Ola forslund Bengt-Goran Hansson Eva Rylander Joakim Dillner Lund University MalmoSweden Sahlgrenska University Hospital GothenburgSweden Karolinska University Hospital StockholmSweden University Hospital UppsalaSweden University of Northern Sweden UmeoSweden Karolinska University Hospital StockholmSweden Sahlgrenska University Hospital GothenburgSweden Sahlgrenska University Hospital GothenburgSweden Lund University MalmoSweden Lund University MalmoSweden Karolinska University Hospital StockholmSweden Lund University MalmoSweden

＜正＞Background:Human papillomavirus（HPV）-based cervical screening is known to increase sensitivity for detection of high- grade cervical intraepithelial neoplasia（CIN）.Randomized trials of longitudinal efficacy ...

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华人消化杂志 1998年第12期6卷 1020-1022页

作者：杨洋夏琼第一军医大学南方医院肿瘤科实验室瑞典哥德堡大学医学部外科教研室

了解ｐ５３基因在结直肠癌发生、转移过程中的动态变化．方法收集患者结肠癌原发灶及肝转移灶石蜡标本６８块．ｐ５３基因ｅｘｏｎ５～９以ＤＧＧＥ及自动ＤＮＡ序列分析来检测．结果３４例中２１例呈ｐ５３变异（６２％），其中５例仅... 详细信息

了解ｐ５３基因在结直肠癌发生、转移过程中的动态变化．方法收集患者结肠癌原发灶及肝转移灶石蜡标本６８块．ｐ５３基因ｅｘｏｎ５～９以ＤＧＧＥ及自动ＤＮＡ序列分析来检测．结果３４例中２１例呈ｐ５３变异（６２％），其中５例仅在肝转移灶发现ｐ５３变异，其余均为原发灶和转移灶一致性的变异．另有２例原发灶即有ｐ５３变异的患者，在转移灶出现了新增加的变异．在３７处变异中２７处（７３％）为错义突变，６处（１６％）无义突变，４处微小插入．在原发、转移灶同时有ｓｉｎｇｌｅｂａｓｅ改变的１４例中，１３例呈现变异的ｐ５３碱基峰和正常峰之比在肝转移灶明显高于结直肠原发灶（Ｐ＜００１）．结论在结直肠癌肝转移过程中，ｐ５３变异主要开始于肠癌原发灶，并被保持于转移至肝脏的癌细胞内，在转移灶其含量或含变异ｐ５３的癌细胞量明显增加．

关键词：结直肠肿瘤肝转移 p53基因

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全球表层土壤中微生物群落的结构及功能

家电科技 2018年第8期 8-8页

作者： Mohammad Bahram Falk Hildebrand Sofia K. forslund Jennifer L. Anderson Nadejda A. Soudzilovskaia Peter M. Bodegom Johan Bengtsson-Patme Sten Anslan Luis Pedro Coelho Helery Harend Jaime Huerta-Cepas Marnix H. Medema Mia R. Maltz Sunil Mundra Pal axel Olsson Mari Pent Sergei Polme Shinichi Sunagawa Martin Ryberg Leho Tedersoo Peer Bork 李巧红(编译)

土壤中存在着地球上最多样化的微生物群落,它们对地球养分循环和碳储存都至关重要。为了更好的了解土壤功能,对土壤微生物的全球分布模式和功能基因序列进行建模,并了解土壤中细菌和真菌群落的多样性和结构之间的生物、环境联系是很有... 详细信息

土壤中存在着地球上最多样化的微生物群落,它们对地球养分循环和碳储存都至关重要。为了更好的了解土壤功能,对土壤微生物的全球分布模式和功能基因序列进行建模,并了解土壤中细菌和真菌群落的多样性和结构之间的生物、环境联系是很有必要的。

关键词：微生物群落表层土壤土壤功能结构土壤微生物基因序列分布模式真菌群落

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磷酸二酯酶3A与动脉高血压

中华高血压杂志 2020年第7期28卷 623-623页

作者：周卫(译) 叶鹏(摘/审校) Ercu M MarkóL Schachterle C Tsvetkov D Cui Y Maghsodi S Theda UP.Bartolomaeus Maass PG Zühlke K Gregersen N Hübner N Hodge R Mühl A Pohl B Molé-Illas R Geelhaar A Walter S Napieczynska H Schelenz S Taube M Heuser A Anistan YM Qadri F Todiras M Plehm R Popova E Langanki R Eichhorst J Lehmann M Wiesner B Russwurm M forslund SK Kamer I Müller DN Gollasch M Aydin A Bohring S Bader M Luft FC Klussmann E 不详

高血压是全球心血管病死亡的主要危险因素。高血压伴短指(趾)畸形综合征在临床上类似于耐盐性原发性高血压,常导致患者在50岁之前因脑卒中而死亡。然而,最近研究者应用磷酸二酯酶3A(phosphodiesterase 3A,PDE3A)编码基因技术进行体内遗... 详细信息

高血压是全球心血管病死亡的主要危险因素。高血压伴短指(趾)畸形综合征在临床上类似于耐盐性原发性高血压,常导致患者在50岁之前因脑卒中而死亡。然而,最近研究者应用磷酸二酯酶3A(phosphodiesterase 3A,PDE3A)编码基因技术进行体内遗传缺陷模型研究,显示突变体PDE3A并未参与其中作用。方法:通过遗传图谱,测序,转基因技术.

关键词：动脉高血压遗传缺陷心血管病原发性高血压主要危险因素脑卒中转基因技术遗传图谱