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Cytokines Expression Profile and Kinetics of Peste des petits ruminants Virus Antigen and Antibody in Infected and Vaccinated Goats

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Virologica Sinica 2012年第4期27卷 265-271页

作者： Arun Patel Kaushal Kishor Rajak Vinayagamurthy Balamurugan Arnab Sen Shashi Bhusan Sudhakar Veerakyathappa Bhanuprakash Raj Kumar Singh awadh bihari pandey Division of Virology Indian Veterinary Research InstituteMukteswar 263138Nainital DistrictUttarakhandIndia Project Directorate on Animal Disease Monitoring And Surveillance(PD_ADMAS) Bangalore 560024KarnatakaIndia Animal Health Division Indian Council of Agricultural Research-North Eastern Hill RegionMeghalaya 793103India Indian Veterinary Research Institute Bangalore 560024KarnatakaIndia National Research Centre on Equines Hisar 125001HaryanaIndia

The present study deals with the co-ordination of cytokine （IL-4 and IFN-7） expression and kinetics of peste des petits ruminants （PPR） virus antigen and antibody in PPRV infected and vaccinated goats. The infected animals exhibited mixed cytokine （both TH1 and TH2） responses in the initial phase of the disease. The infected and dead goats had increased IFN-T response before their death; while IL-4 remained at the base level. The cytokine expression in recovered animals was almost similar to that of vaccinated ones, where a unique biphasic response of IL-4 expression was observed with an up-regulation of IFN-T on 7th days post vaccination （dpv）. Analysis of PPR virus antigen and antibody kinetics in different components of blood from infected and vaccinated animais revealed that the PPR virus antigen load was highest in plasma followed by serum and blood of the infected animals, whereas vaccinated animals showed only marginal positivity on 9th dpv. The antibody titer was high in serum followed by plasma and blood in both vaccinated and infected animals. Therefore, it is inferred that the presence of antigen and antibody were significant with the expression of cytokine, and that a decreased response of IL-4 was noticed during intermediate phase of the disease i.e., 7 to 12m days post infection （dpi）. This indicates the ability to mount a functional TH2 response after 14th dpi could be a critical determinant in deciding the survival of the PPR infected animal.

关键词： Peste despetits ruminants (PPR) Goat Cytokines Real time RT-PCR ELISA

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Landslide Susceptibility Mapping Using RBFN-Based Ensemble Machine Learning Models

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Computer Modeling in Engineering & Sciences 2025年第1期142卷 467-500页

作者： Landslide Susceptibility Mapping Using RBFN-Based Ensemble Machine Learning Models Duc-Dam Nguyen Nguyen Viet Tiep Quynh-Anh Thi Bui Hiep Van Le Indra Prakash Romulus Costache Manish pandey Binh Thai Pham Faculty of Civil Engineering University of Transport TechnologyThanh XuanHa Noi100000Vietnam Faculty of Hydraulic Engineering Hanoi University of Civil EngineeringHa Noi100000Vietnam DDG(R)Geological Survey of India Gandhinagar382010India Research Institute of the University of Bucharest Bucharest050663Romania National Institute of Hydrology and Water Management Bucharest013686Romania Department of Civil Engineering Transilvania University of BrasovBrasov500152Romania Danube Delta National Institute for Research and Development Tulcea820112Romania Marwadi University Research Center(MURC) Marwadi UniversityRajkotGujaratBharat360003India Department of Civil Engineering Faculty of Engineering&TechnologyMarwadi UniversityRajkotGujaratBharat360003India

This study was aimed to prepare landslide susceptibility maps for the Pithoragarh district in Uttarakhand,India,using advanced ensemble models that combined Radial Basis Function Networks(RBFN)with three ensemble learning techniques:DAGGING(DG),MULTIBOOST(MB),and ADABOOST(AB).This combination resulted in three distinct ensemble models:DG-RBFN,MB-RBFN,and ***,a traditional weighted method,Information Value(IV),and a benchmark machine learning(ML)model,Multilayer Perceptron Neural Network(MLP),were employed for comparison and *** models were developed using ten landslide conditioning factors,which included slope,aspect,elevation,curvature,land cover,geomorphology,overburden depth,lithology,distance to rivers and distance to *** factors were instrumental in predicting the output variable,which was the probability of landslide *** analysis of the models’performance indicated that the DG-RBFN model,with an Area Under ROC Curve(AUC)of 0.931,outperformed the other *** AB-RBFN model achieved an AUC of 0.929,the MB-RBFN model had an AUC of 0.913,and the MLP model recorded an AUC of *** results suggest that the advanced ensemble ML model DG-RBFN was more accurate than traditional statistical model,single MLP model,and other ensemble models in preparing trustworthy landslide susceptibility maps,thereby enhancing land use planning and decision-making.

关键词： Landslide susceptibility map spatial analysis ensemble modelling information values(IV)

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Fe–EBT Chelate Complex: A Novel Mean for Growth of α-FeOOH and γ-Fe_2O_3 Nanostructures

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Acta Metallurgica Sinica(English Letters) 2014年第6期27卷 1127-1133页

作者： Gajanan pandey Department of Applied Chemistry Babasaheb Bhimrao Ambedkar University

Acicular goethite（a-Fe OOH） and worm-like maghamite（γ-Fe2O3） nanostructures have been prepared adopting a novel route, using Na2[Fe（HL）2（H2O）2] chelate complex in alkaline medium. It is found that concentration of hydrated Fe（III） ions increased with increasing temperature, which later play a key role in generation of different phases of iron oxide. Phase and morphology of the products are investigated using XRD, FTIR, SEM, and TEM analysis. Using UV–Vis spectra, various electronic transitions of goethite and maghamite particles are examined. Maghamite nanostructures exhibit superparamagnetic property at room temperature. On the basis of experimental observations and analytical data, growth mechanism of the nanostructures is discussed.

关键词： Iron oxide Nanostructures Chemical synthesis Growth mechanism Magnetic properties

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Progress on Medical Implant:A Review and Prospects

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Journal of Bionic Engineering 2023年第2期20卷 470-494页

作者： Ankur pandey Swagatadeb Sahoo Department of Electronics and Communication Engineering National Institute of Technology JamshedpurJamshedpurJharkhand831014India

Medical implant from different materials such as metals,ceramics,polymers and composites have gained a lot of research attraction due to wide applications in medical industry for treatment,surgical operations and preparing artificial body *** this work,we highlight a comprehensive review of medical implant mechanism,various types of implant materials,factors affecting the performance of implant and different characterization *** review provides an overall summary of the state-of-the-art progress on various interesting and promising material-based medical ***,few new prospects are explained from the established theoretical and experimental results for real-life *** study is expected to promote extended interest of scientists and engineers in recent trend of modern biomaterials based medical implant.

关键词： Implant material Biocompatibility Hydroxyapatite Dielectric constant

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Microstructural Features of Spray-Deposited Immiscible Bearing Alloys Al-43Sn and Al-7Sn-1.3Cu-1.3Ni

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Journal of Materials Science & Technology 2003年第5期19卷 437-443页

作者： O.P.pandey Thapar Institute of Engineering & Technology Deemed University Patiala-147004 India

Two commercial grade aluminum based immiscible bearing alloys were spray-deposited using convergent-divergent type of nozzle. The processing parameters for spray-deposition were adjusted in such a way that most of the droplets arrived on the deposition substrate in either liquid or semi-liquid state. The microstructural features of spray-formed and as-cast alloys are compared. In spray-formed alloys equiaxed grains were observed. The cell boundaries and intercellular regions were observed to be decorated with sub-micron sized particles whereas in normal casting the second phase was observed to be segregated along grain boundaries. The morphology and distribution of second phase were observed to have similarity with those in over-spread and atomized powders produced under similar processing conditions. The microstructural features observed with variation in spray conditions are discussed in detail.

关键词： Spray deposition Immiscible bearing alloys Microstructure Atomization

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Effect of ultrasonic assisted sintering on mechanical properties and degradation behaviour of Mg15Nb3Zn1Ca biomaterial

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Journal of Magnesium and Alloys 2021年第6期9卷 1989-2008页

作者： Ajit Kumar Pulak M pandey Department of Mechanical Engineering Indian Institute of TechnologyDelhiNew Delhi 110016India

The present work investigates the effect of ultrasonic power(%)and the time of ultrasonic vibration on the sintered density and ultimate compressive strength(UCS)of Mg15Nb3Zn1Ca fabricated using ultrasonic assisted conventional sintering(UACS).The customized UACS setup was designed and manufactured to conduct the experimentations.A customized ultrasonic stepped horn assembly was used for providing vibrations to the sample during ***,to evaluate the efficacy of ultrasonic vibration parameters,the developed setup was used to sinter Mg15Nb3Zn1Ca composite *** study unveiled an increased sintered density and UCS of the fabricated sample by the increase in ultrasonic power(%).Moreover,a decrease in sintered density and UCS was observed with an increase in the time of ultrasonic vibration beyond a certain *** sintered with the assistance of ultrasonic vibration at 100%ultrasonic power,and 20 min of ultrasonic vibration resulted in a sintered density of 1.928±0.062 g·cm^(-3)and UCS of 234.9±12.3 *** obtained mechanical properties of the fabricated sample were comparable to the properties of cortical *** surface morphology and elemental compositions of samples fabricated using UACS declared a fair dispersion of reinforcement in the matrix containing merely the source *** results of corrosion test have showed that the assistance of ultrasonic vibration suppressed the degradation behaviour of the sintered sample after performing electrochemical study of samples using 3-electorde cell ***15Nb3Zn1Ca fabricated using UACS showed a 50.18%and 9.08%of reduction in corrosion rate over conventionally sintered pure Mg and Mg15Nb3Zn1Ca *** addition,electrochemical impedance spectroscopy(EIS)results indicated an enhanced corrosion resistance of the Mg15Nb3Zn1Ca composite material when fabricated at 100%of ultrasonic power with 20 min of vibration *** from that,electrochemical equivalent circuits also result

关键词： Ultrasonic assisted sintering Magnesium Corrosion EIS Mechanical properties

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Can we constrain the evolution of HI bias using configuration entropy?

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Research in Astronomy and Astrophysics 2021年第2期21卷 82-88页

作者： Biswajit Das Biswajit pandey Department of Physics Visva-Bharati UniversitySantiniketanBirbhum731235India

We study the evolution of the configuration entropy of HI distribution in the post-reionization era assuming different time evolution of HI *** describe time evolution of linear bias of HI distribution using a simple form b(a)=b_(0)a^(n) with different index *** derivative of the configuration entropy rate is known to exhibit a peak at the scale factor corresponding to theΛ-matter equality in the unbiasedΛCDM *** show that in theΛCDM model with time-dependent linear bias,the peak shifts to smaller scale factors for negative values of *** is related to the fact that the growth of structures in the HI density field can significantly slow down even before the onset ofΛdomination in the presence of a strong time evolution of the HI *** find that the shift is linearly related to the index *** obtain the best fit relation between these two parameters and propose that identifying the location of this peak from observations would allow us to constrain the time evolution of HI bias within the framework of theΛCDM model.

关键词： methods analytical-cosmology theory-large scale structure of the universe

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Alkaline phosphatase as a bio-indicator of phosphorus-eutrophy in freshwater ecosystems: A review

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International Journal of Sediment Research 2023年第3期38卷 349-360页

作者： Madhulika Singh Jitendra pandey Ganga River Ecology Research Laboratory Environmental Science Division Centre of Advanced Study in Botany Institute of Science Banaras Hindu University

Limnologists have greatly advanced the understanding of indicators of phosphorus(P)-eutrophy in surface waters. Biotic variables such as macro-invertebrates, fish, zooplankton, benthic algae, and diatoms are extensively used for bio-assessment of eutrophy. New concepts highlight the importance of bed-sediment based “response” variables predicting functional shifts during eutrophication. A cross analysis of studies reveals that alkaline phosphatase(ALP), which serves as a proxy of P-deficiency, and also as an indicator of benthic anoxia/hypoxia-driven feedbacks, can be an easy to measure, cost-effective and reliable tool to assess changes in nutrient stoichiometry, trophic status, and ecological functioning at the sediment-water interface. Here, the issues discussed in this paper are highly relevant to explore new domains of research and “response” based ecosystem models for potential eutrophication management decisions. Because ALP is used in molecular cloning and fingerprinting studies, it is suggested that approaches based on the “omics” technologies need to be used to explore more intricate connections to empirically address ALP-P-eutrophy linkages to track eutrophication in freshwater ecosystems.

关键词： Alkaline phosphatase Sediment based-indicators Ecosystem feedback Nutrient stoichiometry Phosphorus-eutrophy

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Understanding poromechanical response of a biogenic coalbed methane reservoir

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International Journal of Coal Science & Technology 2024年第3期11卷 32-50页

作者： Rohit pandey Satya Harpalani Virginia Tech BlacksburgUSA Southern Illinois University CarbondaleUSA

Biogenic coalbed methane(BCBM)reservoirs aim to produce methane from in situ coal deposits following microbial conversion of *** of BCBM reservoirs requires economic methane production within an acceptable *** work reported here quantifies the findings of previously published qualitative work,where it was found that bioconversion induces strains in the pore,matrix and bulk *** imaging and dynamic strain monitoring techniques,the bioconversion induced strain is quantified *** understand the effect of these strains from a reservoir geomechanics perspective,a corresponding poromechanical model is ***,findings of imaging experiments are validated using core-flooding flow ***,expected field-scale behavior of the permeability response of a BCBM operation is modeled and *** results of the study indicated that,for Illinois coals,bioconversion induced strains result in a decrease in fracture porosity,resulting in a detrimental permeability drop in excess of 60%during bioconversion,which festers itself exponentially throughout its producing *** indicate that reservoirs with high initial permeability that will support higher Darcian flowrates,would be better suited for coal bioconversion,thereby providing a site-selection criteria for BCBM operations.

关键词： Coal bioconversion Poromechanical model Reservoir response Bioconversion induced strain

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Exploration of deep seabed polymetallic sulphides: Scientific rationale and regulations of the International Seabed Authority

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International Journal of Mining Science and Technology 2013年第3期23卷 457-462页

作者： Anju pandey Ministry of Earth Sciences Prithvi Bhavan New Delhi 110003 India

Polymetallic sulphides have been consistent source of metals like iron, copper, zinc and lead. Apart from these they are also seen as economically viable resources of silver and gold. As the demand of these metals is showing an astoundingly increasing trend, the search for their resources has also increased in similar folds. This has resulted in many nations' focus on deep seabed resources of the polymetallic sulphides. Consequently, International Seabed Authority (ISBA) has provided 'Regulations' to obtain plan of work for exploration of polymetallic sulphide deposits in deep seabed 'Area'. Following the release of these Regulations, several countries are in the process of obtaining the licence for exploration of these metals from the deep seabed regions. Detailed information about the science and ISBA Regulations for exploration of polymetallic sulphide deposits is prerequisite to submit an application to ISBA for their exploration. The current contribution provides a comprehensive review of the science behind locating polymetallic sulphide deposits in geological setting of deep seabed as well as about the ISBA Regulations for their exploration.

关键词： Polymetallic sulphide International Seabed Authority Exploration Mid ocean ridges

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