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Determinants of the Use of Health Care and Therapeutic Routes of Populations in Rural Senegalese Areas, 2016

Open Journal of Preventive Medicine 2021年第12期11卷 439-448页

作者： Abdoul Aziz Ndiaye awa ba-diop Maimouna diop Alioune badara Tall Ousseynou Ka Fatou Ndiaye Omar Sy Sylla Ndeye Fatou Ngom Aladji Madior diop Lamine Gueye Anta Tal Dia Université Alioune diop de bambey Bambey Senegal Université Cheikh Anta diop de Dakar Dakar Senegal

In Senegal, access to health care for rural populations and therapeutic choices remain problematic. These problems may be synonymous with insufficient financial resources, long waits, ineffective treatments, or drug shortage in health structures, leading patients to perform various therapeutic behaviours. The aim of this present study was to identify the therapeutic routes of the patients and the determinants of the different uses of health care in the populations of Ferlo. This descriptive and analytical study was carried out as part of the medical consultation days of the 2016 summer at the university in Widou Thiengoly. All patients who met the selection criteria were enrolled. In total, the 150 participants were mainly animal breeders (63.3%) and housewives (26%), also, most were women (90.7%). The analysis of the therapeutic routes showed that the health post was used as first-line and second-line respectively in 85.3% and 59.3% of the study populations. Traditional medicine and self-medication would be used in the third intention. Therapeutic choices were independent of age (p = 0.94), marital status (p = 0.84) and occupation (p = 0.58). On the other hand, social dimensions, such as tradition, appreciation of efficiency, distance, cost, and gender, also determine the use of health care. Women used health post more frequently than men (p = 0.03) (OR: 3.89, CI95% [1.16 - 12.98]) of the order 3.89. The main reasons for self-medication practice were the treatment of headache or fever (46%) and that of fatigue (26%). The prices were more expensive for health facilities (70.9%) than for traditional healers (70% “not expensive at all”) where the waiting time was considered “not long at all” (70%).

关键词： Therapeutic Routes Biomedicine Traditional Medicine Widou Thiengoly

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Preventive Effect of an Extract of Terminalia avicennioides on Acetylcholine-Induced Tracheoconstriction in Wistar Strain Rats

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Open Journal of Respiratory Diseases 2024年第2期14卷 60-68页

作者： awa ba-diop Ndèye Absa Diaw Ibrahima Diouf Mbaye Sène Ouafae Kechaba Mamadou Sarr Modou Oumy Kane Physiology Laboratory Department of Medicine Alioune Diop University of Bambey Bambey Senegal IRL3189 Environment Health Societies CNRS-UCAD Dakar Senegal Department of Physiology Laboratory Faculty of Medicine Cheikh Anta Diop University of Dakar Dakar Senegal Department of Physiology Laboratory Faculty of Medicine UFR Sante Assane SECK University of Ziguinchor Ziguinchor Senegal

Asthma is one of the most common chronic respiratory pathologies worldwide. The cost of its treatment, particularly for populations in developing countries like Senegal, requires an alternative which consists of developing research into new therapeutic approaches with the use of plants from traditional pharmacopoeia. The objective of this study was to determine whether the hydroalcoholic extract of Terminalia avicennioides leaves has a preventive effect on the constriction of tracheal smooth muscle induced by Acetylcholine in Wistar strain rats. Methods: The species used in our experiments were male Wistar rats aged between 12 and 14 weeks. Rings of rat trachea were suspended in isolated organ chambers connected to tension sensors. Two pharmacological agents were used: acetylcholine, for its constrictor effect and adrenaline, for its dilating effect on the pulmonary trachea. Our plant material consisted of a hydroalcoholic extract of Terminalia avicennioides leaves. The experimental protocol was that of the preventive model which consisted of impregnating these rings with the extract at a defined concentration then testing its contractility in the presence of Acetylcholine which was the contractile agonist used in this study. The preventive effect of the extract was studied with an Acetylcholine contraction range on rings pre-incubated with Terminalia avicennioides extract. Results: The results showed that Acetylcholine contracts the trachea and the increase in its contractility was dependent on the dose of Ach added cumulatively (10−5 to 4 × 10−5 mol/l). The administration of the hydroalcoholic extract of Terminalia avicennioides leaves led to a modification of the contractile response to Acetylcholine. Indeed, this extract induced a significant attenuation of the contractile responses of the treated tracheal rings compared to those untreated. Conclusion: Terminalia avicennioides had a relaxing effect on tracheal smooth muscle and this effect

关键词： Bronchial Hyperreactivity Extract Hydroalcoholic of Terminalia Avicennioides Asthma

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Interest of Cardiac Rehabilitation in Patients with Heart Disease in a Cardiology Department in Senegal

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World Journal of Cardiovascular Diseases 2024年第4期14卷 217-227页

作者： awa ba-diop Abdou Khadir Sow Rim Mohamed Khaled Mor Diaw Mame Saloum Coly Fulgence Abdou Faye Amadou Ndiadé bamba Gaye Abdoulaye ba Abdoulaye Samb Laboratory of Physiology and Functional Explorations Department of Medicine Alioune Diop University of Bambey Bambey Senegal IRL3189 Environment Health Societies CNRS-UCAD Dakar Senegal The African Research Network Noncommunicable Diseases Dakar Senegal Laboratory of Physiology and Functional Explorations FMPOS UCAD Dakar Senegal Laboratory of Physiology and Functional Explorations UFR Sant&#233 UAS of Thi&#232s Thi&#232s Senegal INSERM U970 Team 4 Paris France

Cardiac rehabilitation helps improve the prognosis and quality of life for patients with heart disease. To show its interest in the African context, in the management of heart disease, a prospective study was carried out. Its objective was to evaluate the effects of physical rehabilitation on cardiac function. Methods: Patients were evaluated at the beginning and at the end of cardiovascular rehabilitation by cardiovascular, biological, and echocardiographic parameters including the size of the heart chambers, the kinetics of the walls, and the systolic function of the ventricles. Results: The study involved 12 patients, 67% of whom were men. After cardiac rehabilitation, the mean hemodynamic constants had not been significantly modified. However, a significant decrease in Total-Cholesterol, LDL-Cholesterol and triglyceride levels was noted. Mean fasting blood sugar decreased from 1.25 ± 0.48 g/L to 0.92 ± 0.18 g/L and glycated hemoglobin from 7.72% ± 0.01% to 6.45% ± 0.008%. The echocardiographic parameters studied showed an improvement in the dilation of the heart chambers in 8.33% of the patients, the normalization of the ejection fraction of the left ventricle in 16% patients, the improvement of the kinetic disorders in 16% of patients and recovery of right ventricular systolic function in all patients. Conclusion: Cardiac rehabilitation as a secondary preventive measure for cardiovascular disease has contributed significantly to improving the clinico-biological parameters of the disease.

关键词： Cardiac Rehabilitation Heart Disease Cardiovascular Disease

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Profile of Bone Mass and Its Determining Factors in Type 2 Diabetes: Case-Control Study

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Journal of Diabetes Mellitus 2021年第4期11卷 143-158页

作者： Maïmouna Touré Cheikh A. B. Mané Mbaye Sène Abdou K. Sow Ibrahima Diouf Mame S. Coly awa ba-diop Mor Diaw Salimata D. Houndjo Arame Mbengue Fatou Bintou Sar Modou O. Kane Mamadou Sarr Abdoulaye ba Lamine Gueye Abdoulaye Samb Laboratory of Physiology and Functional Explorations Faculty of Medicine Pharmacy and Odontology Cheikh Anta Diop University Dakar Senegal Laboratory of Pharmaceutical Physiology Faculty of Medicine Pharmacy and Odontology Cheikh Anta Diop University Dakar Senegal Physiology Laboratory Faculty of Health Sciences Thies Senegal Faculty of Health and Sustainable Development University Alioune Diop Bambey Senegal IRL 3189 “EHS: Environment Health Societies” CNRS CNRST Bamoko Cheikh Anta Diop University Dakar Senegal

background: Type 2 diabetes mellitus, beyond its well-known cardiovascular and neurological complications, is now increasingly recognized as having deleterious effects on bone tissue. It’s thus presented as an independent risk factor for bone fragility with a considerable fracture risk relating to many more or less intricate parameters. The general objective of our study is to assess bone mass during type 2 diabetes in Senegalese women. Methodology: We had carried out a cross-sectional and descriptive study. Socio-demographic characteristics were collected on the basis of a questionnaire. Then each of the subjects had undergone a complete clinical examination followed by a blood sample for a biological assessment of certain cardiovascular risk factors. Bone mass was measured using a bio-impedancemeter. Results: We recruited 88 women with type 2 diabetes and 83 healthy control women. The mean age of diabetic subjects was 52.7 years ± 6.8 (with extremes of 39 and 74 years). In control, the mean age was 51.0 ± 8.5 years (with extremes of 35 and 72 years). Among the diabetic subjects, 22 subjects or 25% practiced a regular walk against 27 (32.5%) in the control. Forty-three among the diabetic subjects (48.8%) were known hypertensive and followed. According to the body mass index, 71 patients (80.7%) were overweight compared to 59 (71.1%) controls. According to the waist size, 80 (90.9%) diabetic subjects had an elevated waist size compared to 69 control women (83.1%). Among diabetic subjects, 41 patients (46.5%) were hyperglycemic imbalance according to fasting blood glucose and 59 patients (67%) according to glycated hemoglobin level. Thirty-seven diabetics (42%), had both high fasting blood glucose and elevated glycated hemoglobin. The mean duration of diabetes was 8.68 ± 7.18 years. We found significantly higher bone mass in type 2 diabetic subjects (p = 0.03). Among diabetics, 27.3% had low bone mass compared to 36.

关键词： Bone Mass Bone Mineral Density Type 2 Diabetes Senegalese Women

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Phenotypic Detection of Enterobacterales Strains Susceptible of Producing OXA-48 Carbapenemase

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Advances in Microbiology 2024年第2期14卷 115-121页

作者： Abdoulaye Seck Abdou diop babacar Ndiaye Assane Dieng awa ba Amadou diop Chantal Mahou Douala-Djemba Thierno Abdoulaye Diallo Cheikh Anta diop University of Dakar Dakar Senegal Medical Biology Laboratory Pasteur Institute of Dakar Dakar Senegal

background: Nowadays, emergence of Carbapenemase-Producing Enterobacterales (CPE) throughout the world has become a public health problem, especially in countries with limited resources. In recent years, CPE of type OXA-48 (Ambler class D) have been identified in Dakar. The aim of this study was to evaluate the phenotypic detection of OXA-48 CPE using a temocillin disc (30 μg). Methodology: A retrospective study was carried out at Medical Biology Laboratory of Pasteur Institute in Dakar on Ertapenem-Resistant Enterobacterales (ERE) strains isolated from 2015 to 2017. These strains were then tested with a 30 μg temocillin disc. Any strain resistant to temocillin (inhibition diameter Results: Forty-one ERE isolated during the study period were tested, of which 34 (82.9%) were OXA-48 based on phenotypic detection using temocillin disc and confirmed by PCR (100%). OXA-48 CPE strains detected were composed of Klebsiella pneumoniae (n = 14;41.2%), Enterobacter cloacae (n = 8;23.5%), Escherichia coli (n = 7, 20.5%), Citrobacter freundii (n = 3;8.8%), Cronobacter sakazakii (n = 1;3%) and Morganella morganii (n = 1;3%). Conclusion: Temocillin resistance has a good positive predictive value for detecting OXA-48 CPE by phenotypic method, confirmed by PCR. Temocillin is therefore a good marker for detection of OXA-48 CPE except Hafnia alvei.

关键词： Ertapenem Temocillin Phenotypic Detection Carbapenemase-Producing Enterobacterales OXA-48

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Assessment of a Database Management System in a Mammogram Unit of a Radiologic Department in Fann Teaching Hospital (Senegal)

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International Journal of Medical Physics, Clinical Engineering and Radiation Oncology 2017年第4期6卷 401-409页

作者： Mamour Gueye awa Sadikh badiane Sokhna ba diop Mamadou Ly Mame Diarra Ndiaye Gueye Abdoulaye Dione diop Abdoulaye Ndoye diop Marame Fall Gynecologic and Obstetric Clinic Aristide Le Dantec Teaching Hospital Dakar Senegal Department or Radiology Fann Teaching Hospital Dakar Senegal

Objectives: To evaluate a medical data management system of a mammogram unit in a department of Radiology. Methods: This is a qualitative and quantitative assessment study in Fann Teaching Hospital between April 2014 and June 2015 one year after its implementation. The quantitative component consisted of the audit of the database to determine the socio-demographic characteristics of patients and the results of mammograms. The qualitative component assessed users’ experience. For analysis, quantitative data were extracted and transferred to Microsoft Excel. For scale variables, we calculated the averages and extremes. For qualitative variables, we established percentages. Results: During the study period, 433 patients underwent mammograms. The average age of patients was 48 years. The completion rate maintained above 85% was below 26% in the first two months of use. As to the completeness given examinations, it was still above 83%. The results of mammogram examinations were normal in the majority of cases: 96% for the right breast and 95.2% for the left breast. All users had a favourable opinion about the database. The reasons were better work organization, comprehensiveness, accessibility and standardization of information about the patient and especially the immediate availability of statistics. For 60% of these health professionals, complaints related to the use of the software were the time-consuming of filling data. Conclusion: This study mainly describes the perception of health professionals on the computerization of radiological examinations. It offers some advantages, proposes improvements and opens avenues for reflection on the globalization of the computerization of patient records in Radiology.

关键词： Electronic Medical Records Database Mammogram Radiology Dakar

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How a Cancer Registry Was Set Up in Senegal: An Example to Follow for a Developing Country

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Journal of Cancer Therapy 2023年第9期14卷 382-389页

作者： Salif baldé Sokhna diop Niang Oumar ba Mamadou diop Joliot Curie Institute Aristide Le Dantec Hospital Dakar Senegal Departmentof Internal Medicine Dalal Jamm Hospital Dakar Senegal Department of Internal Medicine Idrissa Pouye Hospital Dakar Senegal

Objectives: Senegal, with the support of WHO, had begun the establishment of a National Cancer Registry in 2009, although it had been at a standstill since 1969;the objective of this work was to test the reliability of data collection tools and feasibility stages necessary for the validation of media before the establishment of a national cancer registry. Methodology: We conducted a non-exhaustive preliminary study over a period of three months from the first of January to 31 March 2010 at four major hospitals in Dakar at the time. Results: Two hundred and eighty-nine cases had been identified: 44% of men (n = 127) and 56% of women (n = 162) with a sex ratio of 0.8. The ages ranged from 20 to 90 years with an average of 50 years. The main diagnostic mode was essentially histological, with 76% of cases (n = 219). The most frequent locations were: ORL (ENT meaning Ear, Nose and Throat) with 25% of cases, liver 7% and bronchopulmonary 4.5% of cases. In men, liver cancer was the most common location and women for cervical cancer with 16%. Squamous cell carcinoma was the most common histological type with 68% of cases followed by adenocarcinoma with 22% of cases. Thirty-eight percent of patients were classified as stage III and IV. A quarter of our patients had received palliative treatment. In contrast, 15 (15%) had received chemotherapy and 4% had received radiotherapy. Data collection was satisfactory. Conclusion: Cancer is a reality in Senegal but it remains underdiagnosed. The materials made it possible to make the cancer registry effective throughout the country.

关键词： Registry Cancer Senegal

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Study of the Variation in Total and Reducing Sugars Contents According to the Variety and According to the Position Where the Fruit (Mango) Was Harvested from Five Mango Varieties Exploited in Senegal

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Journal of Biosciences and Medicines 2020年第3期8卷 28-36页

作者： ba Ibrahima Fofana Mouhamadou diop Moussoukhoye Natural Products Laboratory (LPN) Department of Chemistry Faculty of Science and Technology Sheikh Anta Diop University of Dakar Dakar Senegal

In this study, the results show that total sugar contents depend on the variety and the position where the fruit (mango) has been harvested. This variation in total sugar contents is observed according to the following varieties: the Bk (Boukodiekhal) variety (bottom position 45 mg/100 mL) then Bk (intermediate and bottom position 40 mg/100 mL) and with the Dr (Diourou) variety the content according to the intermediate position is 63 mg/100 mL while the content according to its bottom position is 56 mg/100 mL. The same is observed for variety Knt (Kent). For the variety factor, we see that the Dr and Sl (Sierra Leone) varieties are the richest in total sugars. Compared to the variation in reducing sugar content, the effect of position is less pronounced. Nevertheless, the statistical results show that the contents vary according to the varieties. There is a very significant variation in reducing sugar content between certain varieties. The variety Kt (Keitt) (45 mg/100 mL) is the richest in reducing sugars but compared to the lower position of the variety Bk, they are statistically identical. Variety Knt remains the poorest in reducing sugars 20 mg/ 100 mL.

关键词： Mangifera indica L. Sugar Composition Mango Export and Local Consumption

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Family Planning Knowledge and Practices among Reproductive Age Women in Widou Thiengoly, Louga Region, Senegal

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Advances in Reproductive Sciences 2018年第1期6卷 1-11页

作者： Abdoul Aziz Ndiaye Niang Aminata Tall Alioune badara diop-ba awa Ngom-Gueye Ndeye Fatou Dia Mountaga Bop Martial Coly Gaye awa Gueye Lamine Tal-Dia Anta Department of Community Health University of Bambey Bambey Senegal Department Public Health University Cheikh Anta Diop Dakar Senegal

Family planning is an effective intervention to improve the health of the mother, newborn and child. It was introduced in Senegal in the 1960s. Significant disparities were noted between urban and rural areas. This research aimed at measuring family planning methods knowledge and practices among reproductive age women (RAW) in the village of Widou Thiengoly, Louga region, Senegal. A descriptive and analytical cross-sectional study was carried out from 12 to 20 August 2016 and involved 150 RAW with an average age of 29.34 years. They were mostly married (98%), with a fertility rate of 3.22 children/woman. 67.3% of RAW knew at least one FP method and the contraceptive prevalence was 40.7%. Birth spacing is the main reason or utilization for more than half of users, while for non-users, more than half were ignorant of FP. Knowledge and practices of contraception were not related to the age of WCA, or the number of children. Fears or experiences of side effects were barriers to initiation and continuous use of FP methods, hence the importance of focusing awareness campaigns on alleviating fears about side effects.

关键词： Knowledge Practices Family Planning Widou Thiengoly-Senegal

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Case-Control Study on the Vulnerability of Women to HIV, Kaolack, 2019

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Open Journal of Epidemiology 2022年第3期12卷 355-366页

作者： Abdoul Aziz Ndiaye Alioune badara Tall awa ba Diya diop Ndeye Fatou Ngom Papa Gallo Sow Martial Coly Bop Anta Tal Dia Université Alioune diop de bambey Bambey The Republic of Senegal Université Cheikh Anta diop Dakar Dakar The Republic of Senegal

Introduction: Despite a low prevalence that hides disparities between regions and genders, HIV infection in Senegal is progressing. Women are more vulnerable. The objective was to study the determinants of women’s vulnerability to HIV/AIDS infection. Methodology: This was a case-control study carried out at the Kasnack Health Center, Kaolack in 2019. And 80 HIV-positive cases and 240 HIV-negative controls participated in the study. A questionnaire was administered to the selected women after their consent. Data were entered and analyzed using Epi Info and Stata software. Results: the mean age of the cases was 32 ± 9.7 years and that of the controls was 29.5 ± 8.5 years. Women were often housewives or traders;half of them had no schooling. Care was accessible for 74.4% of women. The level of knowledge of means of HIV prevention was medium in 71.3% of cases and 0.8% of controls. That of the modes of transmission was medium in 47.5% of cases and 0.8% of controls. The majority of controls (99.2%) had a low level of knowledge of means of prevention and modes of HIV transmission. Risky practices were 40% and 7.9% among cases and controls, respectively, and vulnerability was 40% and 7.9%, respectively. Conclusion: The level of HIV knowledge is low among most women. It is better in HIV-positive women who are more exposed to risky practices that increase their vulnerability. Reducing this vulnerability requires improving their knowledge and their empowerment.

关键词： HIV Case-Control Knowledge Vulnerability

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