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pregnancy and diabetic retinopathy-considerations for evaluation and treatment:a review

Annals of Eye Science 2023年第3期8卷 11-18页

作者： Tahreem A.Mir avni p.finn Department of Ophthalmology Vanderbilt University Medical CenterNashvilleTNUSA

The prevalence of diabetic retinopathy(DR)continues to increase in pregnant females;these individuals are also at a higher risk of disease *** lack of evidence regarding the safety and efficacy of current treatment options in pregnancy makes disease management particularly *** pregnant women with diabetes should have a prenatal DR screening,as well as receive counseling regarding the progression and management of DR during *** blood glucose and blood pressure control should be *** patients with proliferative diabetic retinopathy(pDR)in the absence of visually significant diabetic macular edema(DME),panretinal photocoagulation(pRp)remains a safe and effective treatment *** significant DME can be treated with focal laser if areas of focal leakage are identified in the macula on fluorescein angiogram,intravitreal steroids or anti-vascular endothelial growth factor(VEGF)agents,The theoretical risk of anti-VEGF agents to the fetus should be considered and the patients should be extensively counselled regarding the risks and benefits of initiating anti-VEGF therapy before initiating *** the decision is made to treat with anti-VEGF agents,Ranibizumab should be the agent of *** conclusion,ophthalmologists should make treatment decisions in pregnant patients with DR on a case-by-case basis taking into consideration disease severity,risk of permanent threat to vision,gestational age,and patient preferences.

关键词： Diabetic retinopathy(DR) pregnancy laser photocoagulation intravitreal steroids anti-vascular endothelial growth factor

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