检索结果-南通市图书馆

Cryptanalysis of efficient semi-quantum secret sharing protocol using single particles

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Physics b 2024年第4期33卷 254-257页

作者：高甘 Department of Electrical Engineering Tongling UniversityTongling 244061China Anhui Engineering Research Center of Intelligent Manufacturing of Copper-based Materials Tongling UniversityTongling 244061China Anhui Joint Key Laboratory of Critical Technologies for High-End Copper-based New Materials Tongling UniversityTongling 244061China

In paper[***.b 32070308(2023)],Xing et *** a semi-quantum secret sharing protocol by using single *** study the security of the proposed protocol and find that it is not secure,that is,the three dishonest agents,bob,C... 详细信息

关键词： security loophole rearranging orders semi-quantum secret sharing single particles

On the improved dynamics approach in loop quantum black holes

在线全文

学校读者我要写书评

暂无评论

Communications in Theoretical Physics 2024年第3期76卷 138-143页

作者： Hongchao Zhang Wen-Cong gan Yungui Gong Anzhong Wang Institute for Theoretical Physics&Cosmology Zhejiang University of TechnologyHangzhou310023China United Center for Gravitational Wave Physics(UCGWP) Zhejiang University of TechnologyHangzhou310023China College of Physics and Communication Electronics Jiangxi Normal UniversityNanchang 330022China GCAP-CASPER Physics DepartmentBaylor UniversityWacoTX 76798-7316United States of America School of Physics Huazhong University of Science and TechnologyWuhanHubei 430074China Department of Physics School of Physical Science and TechnologyNingbo UniversityNingboZhejiang 315211China

In this paper,we consider the b?hmer–Vandersloot(bV)model of loop quantum black holes obtained from the improved dynamics *** adopt the Saini–Singh gauge,in which it was found analytically that the bV spacetime is geodesically *** show that black/white hole horizons do not exist in this geodesically complete ***,there exists only an infinite number of transition surfaces,which always separate trapped regions from anti-trapped *** on the improved dynamics approach adopted in other models of loop quantum black holes are also given.

关键词： loop quantum gravity black hole dynamics approach

Metabolic cell death in cancer:ferroptosis,cuproptosis,disulfidptosis,and beyond

在线全文

学校读者我要写书评

暂无评论

Protein & Cell 2024年第9期15卷 642-660页

作者： Chao Mao Min Wang Li Zhuang boyi gan Department of Experimental Radiation Oncology The University of Texas MD Anderson Cancer CenterHoustonTX 77030USA Department of Molecular and Cellular biology Baylor College of MedicineHoustonTX 77030USA The University of Texas MD Anderson UTHealth Graduate School of biomedical Sciences HoustonTX 77030USA

Cell death resistance represents a hallmark of *** studies have identified metabolic cell death as unique forms of regulated cell death resulting from an imbalance in the cellular *** review discusses the mechanisms of metabolic cell death—ferroptosis,cuproptosis,disulfidptosis,lysozincrosis,and alkaliptosis—and explores their potential in cancer *** review underscores the complexity of the metabolic cell death pathways and offers insights into innovative therapeutic avenues for cancer treatment.

关键词： cell death cancer treatment ferroptosis cuproptosis disulfidptosis

Dynamical Dark Energy in Light of Cosmic Distance Measurements.Ⅰ.A Demonstration Using Simulated Datasets

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Research in Astronomy and Astrophysics 2024年第6期24卷 7-14页

作者： gan Gu Xiaoma Wang Xiaoyong Mu shuo Yuan Gong-bo Zhao National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China University of Chinese Academy of Sciences Beijing 100049China Institute for Frontiers in Astronomy and Astrophysics Beijing Normal UniversityBeijing 102206China

We develop methods to extract key dark energy information from cosmic distance measurements including the bAO scales and supernova(SN) luminosity *** using simulated data sets of the complete DESI,LSST and Roman surveys designed for bAO and SN distance measurements,we show that using our method,the dynamical behavior of the energy,pressure,equation of state(with its time derivative) of dark energy and the cosmic deceleration function can all be accurately recovered from high-quality data,which allows for robust diagnostic tests for dark energy models.

关键词： (cosmology:)dark energy (cosmology:)large scale structure of universe (cosmology:)cosmic background radiation (cosmology:)cosmological parameters

Influence of ion species on extraction characteristicsof mixed ion beams

在线全文

学校读者我要写书评

暂无评论

Chinese Physics b 2024年第9期33卷 444-449页

作者： Ao Xu Pingping gan Xiang Wan Yuanjie shi Institute of Electronic Engineering China Academy of Engineering PhysicsMianyang 621999China

The spatial distributions of different kinds of ions are usually not completely the same in the process of *** order to study the reason for the different characteristics of ion extraction, a simplified simulation model of Cu+ andCr+ ions extraction process was established by 2D3V (two-dimensional in space and three- dimensional in velocity space)particle-in-cell (PIC) method. The effects of different extraction voltages from 0 V to 500 V on the density distribution ofCu+ and Cr+ ions and the change of plasma emission surface were analyzed. On the basis of this model, the ion densitydistribution characteristics of Cu+ ions mixed with Li+, Mg+, K+, Fe+, Y+, Ag+, Xe+, Au+, and Pb+ ions respectivelyunder 200-V extraction voltage are further simulated, and it is revealed that the atomic mass of the ions is the key reason fordifferent ion density distributions when different kinds of ions are mixed and extracted, which provides support for furtherunderstanding of ion extraction characteristics.

关键词： extraction ion species density distribution atomic mass

Oral peptide therapeutics for diabetes treatment: State-of-the-art and future perspectives

在线全文

学校读者我要写书评

暂无评论

Acta Pharmaceutica Sinica b 2024年第5期14卷 2006-2025页

作者： bingwen Ding Zhu Zhu Cong Guo Jiaxin Li Yong gan Miaorong Yu State Key Laboratory of Drug Research and Center of Pharmaceutics Shanghai Institute of Materia MedicaChinese Academy of SciencesShanghai 201203China University of Chinese Academy of Sciences Beijing 100049China School of Pharmacy Henan UniversityKaifeng 475004China NMPA Key Laboratory for Quality Research and Evaluation of Pharmaceutical Excipients National Institutes for Food and Drug ControlBeijing 100050China

Diabetes,characterized by hyperglycemia,is a major cause of death and disability ***,such as insulin and glucagon-like peptide-1(GLP-1)analogs,have shown promise as treatments for diabetes due to their ability to mimic or enhance insulin's actions in the *** to subcutaneous injection,oral administration of anti-diabetic peptides is a preferred ***,biological barriers significantly reduce the efficacy of oral peptide *** advancements in drug delivery systems and formulation techniques have greatly improved the oral delivery of peptide therapeutics and their efficacy in treating *** review will highlight(1)the benefits of oral anti-diabetic peptide therapeutics;(2)the biological barriers for oral peptide delivery,including pH and enzyme degradation,intestinal mucosa barrier,and biodistribution barrier;(3)the delivery platforms to overcome these biological ***,the review will discuss the prospects in this *** information provided in this review will serve as a valuable guide for future developments in oral anti-diabetic peptide therapeutics.

关键词： Oral peptides Diabetes Delivery platforms Insulin Glucagon-like peptide-1 biodistribution biological barriers Targeted delivery

Wearable ultrasensitive and rapid human physiological monitoring based on microfiber Sagnac interferometer

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China(Information Sciences) 2024年第3期67卷 281-290页

作者： Xin WANG Hongyou ZHOU Meihua CHEN Yongcheng HE Zhishen ZHANG Jiulin gan Zhongmin YANG State Key Laboratory Luminescent Materials and Devices Institute of Optical Communication MaterialsSpecial Glass Fiber and Device Engineering Technology Research and Development Center of Guangdong ProvinceGuangdong Provincial Key Laboratory of Fiber Laser Materials and Applied TechniquesSouth China University of Technology Guangdong-Hong Kong-Macao Joint Laboratory for Intelligent Micro-Nano Optoelectronic Technology Foshan University

High-sensitive and fast-responding flexible strain sensors are essential for the smart wearable devices that precisely and dynamically perceive the weak deformations induced by human physiological signals. Here, a flexible strain sensor via polydimethylsiloxane(PDMS)-encapsulated microfiber Sagnac interferometer was designed and prepared for monitoring the human pulse signals and sound vibrations. The sensor achieved a record-breaking sensitivity(gauge factor, GF = 9977) and an extremely low detection limit(0.00025%) due to the strong polarization-dependent coupling effect in the microfiber coupler and the polarization-mixing effect in the Sagnac loop. The relative intensity demodulation method also enabled a fast response time of 10 μs. The wearable pulse measurements were implemented by attaching this flexible strain sensor directly to human skin at various locations and the waveform details were accurately captured. Taking advantage of the ultra-high sensitivity and fast response performance of the prepared sensor, the real-time dynamic acquisition of the underwater weak signal, such as the hydro-acoustic waves with a wide range of 20 Hz–16.86 k Hz, has been demonstrated. These initial results pave the way for a new and innovative category of underwater wearable devices with rapid detection of human physiological signals and weak environmental vibrations.

关键词： flexible strain sensor microfiber Sagnac interferometer underwater detection

mIgM-mediated splenic marginal zone b cells targeting of folic acid for immunological evasion

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Acta Pharmaceutica Sinica b 2024年第2期14卷 808-820页

作者： Huan Wang Zhuxuan Jiang Zhiwei Guo gan Luo Tianhao Ding Changyou Zhan Department of Pharmacology School of Basic Medical Sciences&Department of PharmacyShanghai Pudong HospitalFudan UniversityShanghai 200032China Department of Pharmaceutical Sciences School of PharmacyNaval Medical UniversityShanghai 200433China shanghai Engineering Research Center for Synthetic Immunology Fudan UniversityShanghai 200032China

Folic acid is a fully oxidized synthetic folate with high bioavailability and stability which has been extensively prescribed to prevent congenital *** we revealed the immunosuppressive effect of folic acid by targeting splenic marginal zone b(MZb)*** acid demonstrates avid binding with the Fc domain of immunoglobulin M(IgM),targeting IgM positive MZb cells in vivo to destabilize IgM-b cell receptor(bCR)complex and block immune *** induced anergy of MZb cells by folic acid provides an immunological escaping window for *** conjugation of folic acid with therapeutic proteins and antibodies induces immunological evasion to mitigate the production of anti-drug antibodies,which is a major obstacle to the long-term treatment of biologics by reducing curative effects and/or causing adverse *** acid acts as a safe and effective immunosuppressant via IgM-mediated MZb cells targeting to boost the clinical outcomes of biologics by inhibiting the production of anti-drug antibodies,and also holds the potential to treat other indications that adverse immune responses need to be transiently shut off.

关键词： Membrane-bound IgM Anti-drugantibodies bcell anergy Folic acid Marginal zonebcells bcell receptor biologics Targeting

Synthesis and characterization of iron clusters with an icosahedral [Fe@Fe12]16+ Core

在线全文

学校读者我要写书评

暂无评论

National Science Review 2024年第4期11卷 123-129页

作者： gan Xu Yun-shu Cui Xue-Lian Jiang Cong-Qiao Xu Jun Li Xu-Dong Chen Jiangsu Collaborative Innovation Center of biomedical Functional Materials and Jiangsu Key Laboratory of New Power batteries School of Chemistry and Materials Science Nanjing Normal University Department of Chemistry and Guangdong Provincial Key Laboratory of Catalytic Chemistry Southern University of Science and Technology Department of Chemistry and Engineering Research Center of Advanced Rare-Earth Materials of Ministry of Education Tsinghua University State Key Laboratory of Coordination Chemistry Nanjing University

Iron-metal clusters are crucial in a variety of critical biological and material systems,including metalloenzymes,catalysts,and magnetic storage ***,a synthetic high-nuclear iron cluster has been absent due to the extreme difficulty in stabilizing species with direct iron-iron *** this work,we have synthesized,crystallized,and characterized a（Tp*）4W4S12(Fe@Fe12) cluster(Tp*=tris（3,5-dimethyl-1-pyrazolyl）borate（1-）),which features a rare trideca-nuclear,icosahedral[Fe@Fe12] cluster core with direct multicenter iron-iron bonding between the interstitial iron（Fei） and peripheral irons（Fep）,as well as Fep…Fepferromagnetic *** chemistry studies reveal that the stability of the cluster arises from the 18-electron shell-closing of the [Fe@Fe12]16+core,assisted by its bonding interactions with the peripheral tridentate [（Tp*）WS3]4-ligands which possess both S→Fe donation and spin-polarized Fe-Wσ *** ground-state electron spin is theoretically predicted to be S=32/2 for the *** existence of low oxidation-state（OS～+1.23） iron in this compound may find interesting applications in magnetic storage,spintronics,redox chemistry,and cluster catalysis.

关键词： Fe13 cluster iron-sulfur cluster low-valence iron iron−iron bond high spin complex