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世界核心医学期刊文摘（儿科学分册） 2005年第5期1卷 33-33页

作者： Roy P. Aubert-Jac.uin c. avart c. Gontier c.郭战宏

This study aimed at evaluating the interest of a thic.ened infant formula with lac.ase ac.ivity by c.mparison with a standard infant formula in the management of benign digestive disorders in infants. Infants of both sex (N =109), ranging in age from 0 to 3:months, were inc.uded in a randomised double blind trial. In fants went to the paediatric.an bec.use of benign digestive disorders suc. as re gurgitation, eruc.ation or hic.up, c.lic. persistent c.ying and/or meteorism. Ni ne hundred and three infants were inc.uded and randomised in two parallel groups : they c.nsumed daily either the thic.ened infant formula with lac.ase ac.ivity or a standard infant formula. There were no signific.nt differenc. in the infant s inc.uded in both groups. Both formula were well ac.epted and tolerated. Growth of the infants and c.mplianc. during the study were identic.l and good in the t wo groups. The effic.enc. of the formula tested was showed on digestive symptoms through:a dec.ease of the intensity of the digestive disc.mforts more important in the test than in the standard formula group;a dec.ease of the intensity of t he gaz signific.ntly more important in the test than in the standard formula gro up;signific.nt dec.eases in frequenc. and intensity of gaz in the test group whi le there were no signific.nt diminution in the standard group; This study showed the good toleranc., ac.eptability and effic.enc. of a thic.ened infant formula with lac.ase ac.ivity on benign digestive disorders of young infants.

关键词：机能失调乳糖酶顺从性儿科医师随机双盲可接受性

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